Flex-GTR: Open questions and proposals for ACL, PCL and MCL injury thresholds

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Bundesanstalt für Straßenwesen (Federal Highway Research Institute) TEG-078 Flex-GTR: Open questions and proposals for ACL, PCL and MCL injury thresholds 7th Meeting of the GRSP Flex PLI Technical Evaluation Group Bergisch Gladbach, December 8st, 2008 Oliver Zander Bundesanstalt für Straßenwesen Bundesanstalt für Straßenwesen (Federal Highway Research Institute)

Content ACL/PCL injury thresholds - history and tentative threshold values MCL injury threshold - development and tentative threshold values References Slide No. 2

Content ACL/PCL injury thresholds - history and tentative threshold values MCL injury threshold - development and tentative threshold values References Slide No. 3

ACL/PCL injury thresholds For cruciate ligament injuries, so far no injury risk curve has been developed due to the comparatively low priority within real car accidents. The IHRA/PS just described an example 10 mm from a computer simulation analysis carried out by Dominique Cesari (IHRA, 2004). The EEVC WG 17 PLI uses the knee shear displacement (relative displacement between tibia and femur at the knee joint level in lateral direction) to evaluate cruciate ligament (ACL, PCL) injuries (EEVC, 2002). Knee joint injuries as a reconstructive factors in car-to-pedestrian accidents, Forensic Science International 124 (2001) 74-82 [Source: Teresinski et al, 2001] Slide No. 4

ACL/PCL injury thresholds As no injury risk curve is available, for the time being, an injury threshold tried to be derived from impact tests with the Flex-PLI and the EEVC WG 17 PLI on identical impact locations of different vehicles representing a modern vehicle fleet (1box, sedan, SUV) According to a developed linear regression, it became obvious that the assessment of cruciate ligament protection provided by vehicle bumpers using the FlexPLI ACL/PCL elongation readings is not comparable to the assessment using the WG 17 PLI shearing displacement results and vice versa Slide No. 5

ACL/PCL injury thresholds Therefore, it appears more appropriate to stick with PMHS knee shearing results evaluated by Bhalla et al (2003) that state a tolerance of at least 12,7 mm for knee shear displacement of the 50th male, even though the timing of injury could not be clearly identified: Dynamic shear tests on the TRL legform and POLAR-II knee joint plotted along with two PMHS shear tests performed by UVA) [Source: Bhalla et al, 2003] Slide No. 6

Content ACL/PCL injury thresholds - history and tentative threshold values MCL injury threshold - development and tentative threshold values References Slide No. 7

ACL/PCL injury thresholds Conclusions / Proposal: 1. Under the previously made observations, the following, first estimation could be done: Flex-GT ACL/PCL elongation upper performance limit: 12,7 mm 2. In a next step, a more detailed correlation study between shearing displacement and cruciate ligament elongation could be done, using an appropriate amount of simulations on simplified test rigs and / or real car Tests, representing the current vehicle fleets. Anyway, as the cruciate (ACL) ligament injuries are expected to occur in conjunction with other (MCL) injuries, the common injury mechanisms have to be better understood. Therefore, and for the comparatively low relevance within real pedestrian accidents, for the time being, a threshold of 12,7 mm ACL/PCL elongation could be proposed as performance limit for monitoring purposes only. Slide No. 8

Content ACL/PCL injury thresholds - history and tentative threshold values MCL injury threshold - development and tentative threshold values References Slide No. 9

MCL injury threshold Currently proposed, tentative MCL injury threshold: 18 20 mm elongation 18 knee bending angle are based on Ivarsson et al (2004): Eight intact knee specimens were subjected to symmetric valgus 4-point bending. The only major load bearing structure injured was the MCL. Schematic of the set-up used in the valgus 4-point bending test of intact knee specimens [Source: Ivarsson et al, 2004] Moment-deflection responses were scaled down to 50th male Two definitions for knee injury occurence: a) time of first local moment peak and b) time of maximum moment Development of Weibull survival models predicting the risk of knee injury Development of dynamic response corridors around the characteristic average responses using standard deviation calculations Slide No. 10

MCL injury threshold Proposal for higher performance limit: 18 knee bending angle Univariate Weibull survival models predicting the risk of knee injury (MCL injury) in dynamic valgus bending of the 50th percentile male knee as function of bending angle [Source: Ivarsson et al, 2004] Questions: Why injury definition B (injury occurence at the time of maximum moment) and not definition A (injury occurence at time of first peak)? Why no use of the dynamic response corridor (16-20 / 12,5-15 ) but just the average value? Slide No. 11

MCL injury threshold 20 knee bending angle are based on Konosu et al (2001): Several dynamic PMHS tests from Kajzer et al (1997, 1999) were taken to obtain the human knee characteristics versus bending mode. A logistic analysis method from Nakahira et al (2000) was applied to the test results and an injury risk curve against the bending angle was obtained. From this risk curve, the bending angle at 50% injury risk is 19,8 Proposal for lower performance limit: 19,8 knee bending angle PMHS test results (dynamic impact test) [Source: Kajzer et al, 1997] Injury risk curve against bending angle [Source: Konosu et al, 2001] Slide No. 12

MCL injury threshold Transformation of human knee bending angle human model knee bending angle human model knee MCL elongation Flex-GT model knee MCL elongation Flex-GT knee MCL elongation Transformation of human knee bending angle [Source: Konosu 2007] Slide No. 13

MCL injury threshold Transformation of human model knee MCL elongation Flex-GT model knee MCL elongation a) not including high-bumper vehicles: b) including high-bumper vehicles: Deduction of Flex-GT MCL elongation thresholds [Source: Yamaguchi / Takahashi 2008] Questions: Number and kind of simplified vehicle models used for transformation of human model results? How many high-bumper vehicles included afterwards? Are simplified car models and car model fleet representative? Derivation from which statistics? Slide No. 14

MCL injury threshold Effect of muscle tone is estimated at 10% in valgus bending Anyway, a modification of the lower performance limit by 10% would mislead to the assumption of MCL failure / rupture at 23 (instead of 12,5 20) mm knee elongation The effect of muscle tone therefore should be considered within the knee stiffness This higher knee stiffness was understood being taken into account already within the development of the Flex-GTα: Knee bending characteristics [Source: Konosu 2006] Slide No. 15

Content ACL/PCL injury thresholds - history and tentative threshold values MCL injury threshold - development and tentative threshold values References Slide No. 16

MCL injury threshold Conclusions / Proposal: 1. As starting point, the dynamic bending limit response corridor according to injury definition B [approx 16 20 ] and the inkury risk curve by Konosu (2001) [19,8 ]for a 50% injury risk might be appropriate 2. Those bending limits could be used (as before) as human model knee bending angle and then be transformed accordingly into: human model knee MCL elongation Flex-GT model knee MCL elongation (= Flex-GT knee MCL EL) 3. Under the previously made observation (Human knee bending angle [deg] ~ Flex-GT MCL elongation [mm]) the following,first estimation could be done: Flex-GT MCL elongation lower performance limit: 20 mm Flex-GT MCL elongation upper performance limit: 16 mm 4. Note: Effect of muscle tone has already been taken into account High bumper vehicles still have to be taken into account in an appropriate, weighted manner Slide No. 17

Content ACL/PCL injury thresholds - history and tentative threshold values MCL injury threshold - development and tentative threshold values References Slide No. 18

References Bhalla K., Bose D., Madeley N., Kerrigan J., Crandall J. 2003. Evaluation of the response of mechanical pedestrian knee joint impactors in bending and shear loading. Paper no. 429 of ESV conference proceedings 2003. EEVC Working Group 17. 2002. Improved test methods to evaluate pedestrian protection afforded by passenger cars. December 1998 report with September 2002 updates. International Harmonised Research Activities (IHRA). Draft Meeting Minutes for the 16th Expert Meeting of IHRA Pedestrian Protection. Australia, 2004. Ivarsson J., Lessley D., Kerrigan J., Bhalla K., Bose D., Crandall J., Kent R. 2004. Dynamic response corridors and injury thresholds of the pedestrian lower extremities. IRCOBI conference proceedings 2004. Kajzer J., Matsui Y., Ishikawa H., Schroeder G., Bosch U. Shearing and bending effect at the knee joint at high speed Lateral Loading. SAE Paper No. 973326, 41st STAPP, 1997. Kajzer J., Matsui Y., Ishikawa H., Schroeder G., Bosch U., Shearing and bending effect at the knee joint at low speed lateral loading. SAE Paper No. 1999-01-0712, Occupant Protection SAE SP-1432, 1999. Konosu A., Ishikawa H., Tanahashi M. 2001. Reconsideration of injury criteria for pedestrian subsystem legform test - problems of rigid legform impactor -. Paper no. 01-S8-O-263 of ESV conference proceedings 2003. Konosu A. Information on the flexible pedestrian legform impactor GT alpha (Flex-GTα). 3rd meeting of FlexTEG (Technical Evaluation Group). Doc TEG-021, Bergisch Gladbach, Germany, 2006. Konosu A. Review of Injury Criteria and Injury Thresholds for Flex-PLI. 5th meeting of FlexTEG (Technical Evaluation Group). Doc TEG-048, Bergisch Gladbach, Germany, 2008. Nakahira Y. et al. A combined evaluation method and a modified maximum likelihood method for injury risk curves. IRCOBI 2000. Yamaguchi S., Takahashi Y. Proposed injury threshold for the FlexPLI medial collateral ligament. Japan Automobile Manufacturers Association Inc., Vehicle Safety Subcommittee and Pedestrian Safety WG. Slide No. 19

Thank you! Bundesanstalt für Straßenwesen (Federal Highway Research Institute) Slide No. 20