ARKANSAS TECH UNIVERSITY DEPARTMENT OF NURSING

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ARKANSAS TECH UNIVERSITY DEPARTMENT OF NURSING NUR/BIOL 3803-001 APPLIED PATHOPHYSIOLOGY Spring 2017

STATEMENT OF UNDERSTANDING I have read and understand the syllabus for the course NUR/BIOL 3803. I understand the requirements for this course and grading procedures. STUDENT SIGNATURE DATE 2

ARKANSAS TECH UNIVERSITY Department of Nursing Course: Nur/Biol 3803 Course Title: Applied Pathophysiology Course Faculty: Cynthia Jones, MN, RN Office: Dean Hall 224G Office Phone: 964-0438 Office Hours: Posted on bulletin boards E-mail: cjones1@atu.edu Course/Catalogue Description: Prerequisites: BIOL 2014 and BIOL 3074. This course focuses on the mechanisms and concepts of selected pathological disturbances to the human body. Emphasis is placed on how the specific pathological condition effects the functioning of the system involved as well as its impact on all other body systems. Optional Textbook: Story, L. (2015) Pathophysiology A Practical Approach (2 nd Ed.). Burlington: Jones & Bartlett. ISBN: 978-1-284-04389-1 Optional: Pathophysiology Made Incredibly Easy! (3 rd Ed.). Ambler: Lippincott, Williams, & Wilkins. Credit Hours: Contact Hours: Placement: 3 Semester Hours 3 Contact Hours/Weekly Summer, Fall or Spring Sophomore or Junior year Justification/Rationale for the Course This course assists the student to think critically and apply scientific and quantitative reasoning. 3

Course Objectives: Upon satisfactory completion of this course, the student will be able to: 1. Analyze various ways in which innate adaptive and compensatory physiological mechanisms are effected by specific pathological conditions. 2. Explain the physiological processes, interactions, and controls to be considered in maintaining dynamic equilibrium in the human body in the specific areas of: a. Oxygen and carbon-dioxide exchange and transport b. Fluid, electrolyte, and acid-base balance 3. Delineate the role and function of body defense mechanisms. 4. Predict multiple system responses to selected pathological states. Assessment Methods: l. Grading scale: A - 90-100 B - 80-90 C - 75-80 D - 68-74 F - 67 or below 2. A grade of "C" or above must be achieved in every nursing course to progress in the nursing program. 3. A grade of "I" may be recorded for a student whose work is incomplete due to circumstances beyond the student's control. The student must take responsibility for removal of the incomplete grade according to the Arkansas Tech University's catalog requirements. 4. Examinations will be taken at designated times. If a student cannot take the exam at the regularly scheduled time, he/she is responsible for notifying the instructor as soon as possible to make arrangements to make up the examination. The makeup exam will be in the form of an essay. 4

5. Course Grade The grade will be based on homework, (7) unit examinations and a comprehensive final examination. Unit Exams 85% Final Exam 15% Total 100% 5

CONDUCT OF THE COURSE POLICIES Attendance: As professionals, you must be responsible for your own learning experiences. You are responsible to make the most of all educational opportunities. This is a mark of professionalism. Attendance in class reflects your dedication and the value you place on your chosen profession. We, the faculty, expect you to attend ALL CLASSES. The Arkansas Tech University catalog provides content concerning class attendance. ATU is required to document attendance. Tardy Policy: Regular and timely attendance in theory classes and practicum is considered essential if students are to receive maximum benefit from the nursing courses. The Nursing Department has implemented a policy, which we believe will discourage unnecessary tardiness and absences, but will not punish those conscientious students who must be absent from time to time for unavoidable reasons. At the discretion of the instructor, a student who is tardy or absent may be allowed to complete a quiz or receive a handout if the student has been courteous enough to call the nursing department or call/e-mail the instructor before class to inform of the possibility of tardiness or absentness. This is solely at the discretion of the instructor. Students are responsible for obtaining any missed information after class. Disrupting the learning of other students to ask questions or copy notes of the missed class time while class is in progress is inconsiderate. Dress and Behavior: 1. Students are expected to dress appropriately while attending class. 2. Smoking and chewing tobacco are not permitted in any classroom. 3. Cell phones MUST be off during class. 4. No MP3, IPod, or any other electronic device used in class. Tape recorders allowed. 6

Academic Honesty: Students are expected to be honest and truthful in both classroom and practicum experiences. They are expected to adhere to the Code of Ethics and uphold current standards of care. Students are referred to the Arkansas Tech University Student Handbook for more specific regulations regarding academic honesty. Students are expected to only use authorized devices or materials for an examination and not copy from other Cell Phone Policy: There is a NO cell phone policy for all upper division testing/test review. This includes paper/pencil testing, test review, cooperative testing, and computer testing. If you are discovered with having a cell phone on your person, this will be considered a violation of the Academic Honesty Policy. If we discover that you have your cell phone with you during a unit exam/cooperative testing or unit exam review you will receive a 0 for the test grade. Teacher Role: Resource person, Evaluator, and Facilitator Student Roles: Learner, and Communicator Teacher-Learning Strategies: Lecture, class discussion, audiovisual material Discrimination Statement: Arkansas Tech University does not discriminate on the basis of color, sex, sexual orientation, gender identity, race, age, national origin, religion, veteran status, genetic information, or disability in any of our practices, policies, or procedures. If you have experienced any form of discrimination or harassment, including sexual misconduct (e.g. sexual assault, sexual harassment, stalking, domestic or dating violence), we encourage you to report this to the institution. If you report such an incident of misconduct to a faculty or staff member, they are required by law to notify Arkansas Tech University s Title IX Coordinator and share the basic fact of your experience. The Title IX Coordinator will then be available to assist you in understanding all of your options and in connecting you with all possible resources on and off campus. For more information please visit: http://www.atu.edu/titleix/index.php. Disability Statement: Arkansas Tech University adheres to the requirements of the Americans with Disabilities Act in order to prevent barriers to academic accessibility. If you need an accommodation due to a disability, please contact the ATU Office of Disability Services, located in Doc Bryan Student Center, Suite 171, or visit http://www.atu.edu/disabilities/index.php. 7

NUR/BIOL 3803 - Applied Pathophysiology UNIT I - Orientation to Pathophysiology/Fluid & Electrolytes/Acid & Base 1. Describe the course objectives and position in the curriculum. 2. Utilize knowledge of fluid, electrolytes, acid, base, and the inflammatory process to determine their effects in specific pathological conditions. NUR/BIOL 3803 - Applied Pathophysiology UNIT II - Respiratory Disorders 1. Discuss the normal anatomy and physiology of the respiratory system. 2. Discuss the pathophysiology of infectious/ inflammatory processes of the respiratory system including asthma, pneumonia, and tuberculosis. 3. Discuss the pathophysiology of degenerative/ deficient processes of the respiratory system including emphysema and respiratory distress syndrome. 4. Describe the pathophysiology of the genetic/ congenital abnormalities of the respiratory system including cystic fibrosis. 8

NUR/BIOL 3803 - Applied Pathophysiology UNIT III - Integumentary disorders 1. Discuss the normal anatomy of physiology of the integumentary system. 2. Discuss the pathophysiology of inflammatory processes of the integumentary system including burns and ultraviolet skin damage. NUR/BIOL 3803 - Applied Pathophysiology UNIT IV - Musculoskeletal Disorders 1. Discuss the normal anatomy and physiology of the musculoskeletal system. 2. Discuss the pathophysiology of infectious/ inflammatory processes of the musculoskeletal system including fractures, osteomyelitis, osteoarthritis, and gout. 3. Discuss the pathophysiology of degenerative/ deficiency processes of the musculoskeletal system including scoliosis, osteoporosis, and muscular dystrophy. 9

NUR/BIOL 3803 - Applied Pathophysiology UNIT V - Hematologic Disorders 1. Explain the functions of blood. 2. Trace the hematopoiesis of red blood cells and platelets. 3. Differentiate between red cell antigens and antibodies in persons with type A, B, AB, and O blood. 4. Explain the determination of the RH factor. 5. Explain the functions of blood vessels, platelets, and coagulation factors. 6. Cite normal values for hematologic tests including hemoglobin, red blood cells, hematocrit, white blood cells, and platelets. 7. Discuss the pathophysiology of infectious/ inflammatory processes of the hematologic system including sepsis and disseminated intravascular coagulation (DIC). 8. Discuss the pathophysiology of degenerative/deficiency processes of the hematologic system including acquired anemias (iron deficiency anemia, megaloblastic anemias, pernicious anemia, and folic acid deficiency anemia), anemias of bone marrow failure, hemolytic anemias, and secondary anemias. 9. Describe the disorders resulting from genetic/ congenital influences on the hematologic system including thalassemias, sickle cell anemia, and hemophilia. 10

NURBIOL/ 3803 - Applied Pathophysiology UNIT VI Endocrine metabolism 1. Describe the structure and function of the organs and hormones of the endocrine system and their regulation. 2. Cite diagnostic tests related to endocrine function including hormone levels and BMR. 3. Discuss the degenerative/deficiency processes of the endocrine system including the hypofunction of the pancreas (diabetes mellitus); and the hyperfunction and hypofunction of the thyroid, parathyroid, and adrenals, and anterior pituitary. 4. Discuss the effect of acute metabolic stress on the bodies metabolism. 5. Describe how insulin, catecholamines, thyroid hormone, cortisol and growth hormone effect the metabolism of fats, sugars, and proteins. NUR/BIOL 3803 - Applied Pathophysiology UNIT VII - Gastrointestinal Function, Biliary Tract, and Exocrine Pancreatic Disorders 1. Discuss the normal anatomy and physiology of the gastrointestinal system. 2. Discuss the pathophysiology of infectious/ inflammatory processes of the gastrointestinal system including gastroesophageal reflux disease, gastritis and inflammatory bowel disease. 3. Discuss the pathophysiology of degenerative/ deficient processes of the gastrointestinal system including ulcers and bowel obstruction. 4. Discuss the normal anatomy and physiology of the biliary tract, and exocrine function of the pancreas. 5. Discuss the pathophysiology of infections/ inflammatory processes of the biliary tract and the exocrine pancreas including hepatitis, cirrhosis, cholecystitis, cholelithiasis, and pancreatitis. 6. Discuss the pathophysiology of eating disorders. 11

NUR/BIOL 3803 - Applied Pathophysiology UNIT VIII - Urinary Disorders 1. Discuss the normal anatomy and physiology of the urinary system. 2. Discuss the pathophysiology of infectious/ inflammatory processes in relation to the urinary system including urinary tract infection, pyleonephritis, glomerulonephritis, and nephrotic syndrome. 3. Discuss the pathophysiology of the degenerative/ deficient processes of the urinary system including renal calculi and renal failure. NUR/BIOL 3803 - Applied Pathophysiology UNIT IX - Immunologic Disorders 1. Describe the structure and function of the immune system. 2. Describe mechanisms of infectious disease. 3. Discuss the pathophysiology of infectious/ inflammatory processes of the immune system including HIV, and rheumatoid arthritis. 12

NUR/BIOL 3803 - Applied Pathophysiology UNIT X - Neurologic Disorders/Sensory/Pain 1. Discuss the normal anatomy and physiology of the neurological system. 2. Discuss the pathophysiology of infectious/ inflammatory processes in relation to the neurological system including meningitis and head trauma. 3. Discuss the pathophysiology of the degenerative/ deficient disorders of the neurological system including multiple sclerosis, Parkinson s, CVA, and epilepsy. 4. Discuss the normal anatomy and physiology of the eyes. 5. Discuss the pathophysiology of degenerative/ deficient processes of the eyes including glaucoma, cataract formation, retinal detachment, diabetic retinopathy, and retinal degeneration. 6. Discuss the normal anatomy and physiology of the ears. 7. Discuss the pathophysiology of conductive hearing impairment and sensorineural hearing impairments. 8. Discuss the pathophysiology of degenerative/ deficient processes of the ear caused by the aging process. 9. Discuss the pathophysiology of pain; both acute and chronic. 10. Discuss how neurotransmission of pain signals modulated at the receptor, spinal cord, and brain. 13

NUR/BIOL 3803 - Applied Pathophysiology UNIT XI - Cardiovascular Disorders 1. Discuss the normal anatomy and physiology of the cardiovascular system. 2. Discuss the pathophysiology of the infectious/ inflammatory processes in relation to the cardiovascular system including pericarditis and thrombophlebitis. 3. Discuss the pathophysiology of the degenerative/deficient processes of the cardiovascular system including hypertension, CHF, hyperlipidemia, arteriosclerosis/ atherosclerosis, myocardial infarction, and cardiomyopathy. NUR/BIOL 3803 - Applied Pathophysiology UNIT XII - Neoplastic Disorders 1. Discuss basic principles of neoplastic disorders including common terms, epidemiology, incidence, pathogenesis, etiology, predisposing factors, and impact of cancer. 2. Describe the prevention and assessment of cancer including cancer cell growth, classification of neoplasms, prevention, diagnosis, staging, and grading. 3. Discuss the treatment of cancer including surgery, radiation, chemotherapy, hormonal therapy, biotherapy, targeted therapy, bone marrow, and peripheral blood stem cell transplantation. 14