LIVER DISEASE WRAP-UP

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20th Annual LIVER DISEASE WRAP-UP An Update on Advances in Clinical Hepatology An update on advances in clinical hepatology presented at the 2017 AASLD Meeting for Practicing Internists, Gastroenterologists, and Primary Care Physicians.

PROGRAM SCHEDULE 7:30 am Registration and Continental Breakfast 7:50 Welcome and Introduction 8:00 20th Anniversary of Hepatology at Michigan 8:20 Hepatitis B and C 8:30 NAFLD and Alcoholic Liver Disease Monica Konerman, MD 9:00 Hepatitis Case Discussions 9:45 Question and Answer Panel Moderator: Panel: Monica Konerman, MD 10:00 Break 10:20 Cirrhosis and Portal Hypertension 10:50 Hepatocellular Carcinoma and Hepatotoxicity 11:20 Advanced Liver Disease Case Discussions Jessica Mellinger, MD 12:00 pm Question and Answer Panel Moderator: Panel: Jessica Mellinger, MD 12:20 Course Adjourns COURSE FACULTY Professor, Medical Director, Liver Transplantation Monica Konerman, MD Assistant Dean for Clinical Research, Alice Lohrman Andrews Research Professor in Hepatology, Professor, Director, Clinical Hepatology Jessica Mellinger, MD Assistant Professor, PLANNING COMMITTEE Professor, Medical Director, Liver Transplantation Assistant Dean for Clinical Research, Alice Lohrman Andrews Research Professor in Hepatology, Professor, Director, Clinical Hepatology Chung Owyang, MD H. Marvin Pollard Professor, Chief, Director, Digestive Health Center

PROGRAM OBJECTIVES This seminar will summarize presentations made at the 68th American Association for the Study of Liver Diseases (AASLD) meeting held in Washington D.C. in October 2017. New information regarding the management of hepatitis C, fatty liver disease, liver cancer, and complications of portal hypertension and cirrhosis will be presented. In addition, case-based discussions on the current approach to patients with hepatitis C and patients with advanced liver disease will be provided. At the conclusion of this seminar, participants will be able to: determine what tests to order to diagnose chronic hepatitis B and C, when to initiate antiviral therapy, which treatment is appropriate, and how to monitor for response. understand the clinical course and predictors of outcomes of patients with fatty liver disease and alcoholic liver disease and be able to determine when treatment should be initiated, which treatment is most appropriate, and how to monitor for response. determine the most appropriate approach to the management of patients with hepatocellular carcinoma including the use of resection and transplantation. provide appropraite management for complications of portal hypertension in patients with cirrhosis including bleeding, ascites, and hepatic encephalopathy. TARGET AUDIENCE This course is directed to family and general practitioners, gastroenterologists, internists, and other primary care providers including nurse practitioners and physician assistants interested in expanding their knowledge of clinical hepatology. COURSE BACKGROUND The Liver Disease Wrap-up CME course has been a well-received educational forum for practicing physicians wanting to keep up with the latest developments in clinical hepatology. Experienced faculty from the University of Michigan, provide a mix of clinical research findings along with case-based learning in this program. COMMENTS FROM PAST ATTENDEES As always this conference does not disappoint. The speakers are always excellent and willing to talk to participants. You can t get any better than Dr. Lok and Dr. Fontana at a Hepatology Conference! Very good conference. The case discussions were a highlight! This conference is always the best that I attend each year. I always come away with practical management information that I can implement in patient care UPCOMING CME COURSES 30th Annual Update in Pulmonary & Critical Care Medicine Friday - Saturday, October 13-14, 2017 The Dearborn Inn, Dearborn, MI State of the Art: Kidney and Pancreas Transplantation Thursday, October 19, 2017 Hilton Garden Inn, Troy, MI Movement and Memory Disorders Update Friday, October 20, 2017 Laurel Manor, Livonia, MI 6th Annual Western Michigan Liver Round-Up Saturday, November 4, 2017 Amway Grand Plaza Hotel, Grand Rapids, MI 2017 - SAVE THE DATE Advancing Outpatient Diabetes Care Saturday, April 7, 2017 13th Annual Advanced Liver Disease and Liver Transplantation Update 2017 Friday, May 11, 2017 Sheraton Detroit Novi Hotel, Novi, MI 6th Annual Internal Medicine Spring Review Friday - Saturday, May 18-19, 2018 36th Annual Internal Medicine Update Friday - Sunday, July 27-29, 2018 Grand Hotel, Mackinac Island, MI 31st Annual Cardiology Update Friday - Sunday, August 17-19, 2018 Grand Hotel, Mackinac Island, MI

DATE & TIME, 7:30 am 12:20 pm LOCATION The Inn at St. John s 44045 Five Mile Rd., Plymouth, MI 48170 Phone: (734) 414-0600 Fax: (734) 414-0606 www.stjohnsgolfconference.com REGISTRATION You are encouraged to register as soon as you are certain of attending as we cannot guarantee educational materials for applicants who are not preregistered and prepaid by Friday, November 24, 2017. Payment must accompany registration. Checks should be made payable to the University of Michigan in U.S. currency. Payments by American Express, Discover, MasterCard or Visa are also accepted. The registration fee includes continental breakfast, coffee service, and course materials for participants. CONFIRMATION Conference registrations will be confirmed by email. If you have any questions, please call (734) 232-3469 or email intmedcme@umich.edu. ACCREDITATION The University of Michigan Medical School is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to provide continuing medical education for physicians. The University of Michigan Medical School designates this live activity for a maximum of 4 AMA PRA Category 1 Credits. Physicians should claim only the credit commensurate with the extent of their participation in the activity. Applications have been submitted to the American Osteopathic Association and the American Academy of Family Physicians for credits. Determination of credit is pending. Other credits by specialty may apply. ABIM MOC CREDIT Successful completion of this CME activity, which includes participation in the evaluation component, enables the participant to earn up to 4 MOC points in the American Board of Internal Medicine s (ABIM) Maintenance of Certification (MOC) program. Participants will earn MOC points equivalent to the amount of CME credits claimed for the activity. It is the CME activity provider s responsibility to submit participant completion information to ACCME for the purpose of granting ABIM MOC credit. CANCELLATION POLICY An administrative fee of $50 will be deducted from your registration payment. Refund requests must be received in writing, no later than Friday, November 24, 2017. No refunds will be made thereafter. COURSE SYLLABUS An electronic syllabus will be available to download during and a week after the course. The URL will be provided at the course. A printed syllabus can be purchased for an additional fee. The printed syllabus must be purchased no later than Friday, November 24, 2017. DRIVING DIRECTIONS From the East Follow I-96 until it turns into M-14. Follow M-14 west to Sheldon Road exit. Turn right onto Sheldon Road. Follow Sheldon Road for about half a mile. Turn right onto Five Mile Road. Entrance to The Inn at St. John s is on the right. From the West Follow M-14 east to Sheldon Road exit. Turn right onto Sheldon Road. Follow Sheldon Road for about half a mile. Turn right onto Five Mile Road. Entrance to The Inn at St. John s is on the right. From the South Take I-275 north to M-14. Exit onto M-14 west towards Ann Arbor. Follow M-14 west to Sheldon Road exit. Turn right onto Sheldon Road. Follow Sheldon Road for about half a mile. Turn right onto Five Mile Road. Entrance to The Inn at St. John s is on the right. From the North Take I-275 south to M-14. Exit onto M-14 west towards Ann Arbor. Follow M-14 west to Sheldon Road exit. Turn right onto Sheldon Road. Follow Sheldon Road for about half a mile. Turn right onto Five Mile Road. Entrance to The Inn at St. John s is on the right. CONTACT US University of Michigan Continuing Medical Education 24 Frank Lloyd Wright Dr., Lobby J, Suite 1200 Ann Arbor, MI 48106 Phone: (734) 232-3469 Fax: (734) 998-0085 Email: intmedcme@umich.edu www.med.umich.edu/intmed/cme

REGISTRATION FORM 20th Annual Liver Disease Wrap-Up Mail this form to: University of Michigan CME 24 Frank Lloyd Wright Dr. Lobby J, Suite 1200 Ann Arbor, MI 48106-5750 Online: medicine.umich.edu/dept/intmed Fax: (734) 998-0085 If you are purchasing a printed syllabus please register by Friday, November 24. REGISTRANT NAME (first, middle initial, last) DEGREE - select all that apply (as you would like it to appear on your name tag) MD DO PhD PA NP RN Other: SPECIALTY: PREFERRED MAILING ADDRESS...select one HOME BUSINESS ADDRESS CITY STATE ZIP OR POSTAL CODE COUNTRY CONTACT PHONE NUMBER(S): CELL / HOME EMAIL ADDRESS (Receipts and confirmations are sent via email. Please print clearly.) WORK SPECIAL ACCOMMODATIONS REGISTRATION OPTIONS GENERAL RATE U-M FACULTY & STAFF RATE GI DIVISION FACULTY & STAFF FULL COURSE $105 $50 $0 (pre-registration is still required) PRINTED SYLLABUS (BE GREEN!) Electronic syllabus is free $15 $15 $15 Please enclose a check (U.S. currency) payable to the University of Michigan or pay by credit card below. Payment must accompany registration. CREDIT CARD: AmEx Discover MasterCard Visa CARD # EXP. DATE SECURITY CODE NAME ON CARD (Please print) SIGNATURE (Not valid without signature) Liver Disease Wrap-Up December 2, 2017