Radiation Protection Research. From FP6 to FP7. Neale Kelly

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Transcription:

Radiation Protection Research From FP6 to FP7 Neale Kelly

Risks at low and protracted doses Topic % Radiobiology 46 Epidemiology 25 Medical uses 7 Risk and emergency management Other topics Radioecology and environmental protection 15 Dosimetry 0.6 Education and training 1 Distribution of FP6 budget 5

Trends between FP5 and FP6 FP5 % FP6 % Risks at low doses 47 71 Medical uses and natural radiation Risk and emergency management 12 7 18 15 Radioecology 10 5 Dosimetry 13 0.6

Radiobiology Integrated Projects RISC-RAD (16 M ) multi-disciplinary approach to better understanding of mechanisms and quantification of risk DNA damage and repair, genomic instability, mechanisms of tumorigenesis, genetic susceptibility, individual sensitivity, modelling NOTE (11 M ) non targeted effects of radiation mechanisms underlying NTE, effect on cancer risk at low doses, influence on non-cancer disease, etc implications for radiation protection

Radiobiology - STREPS ERA-PRO (0.4 M ) database of animal radiobiology studies in EU, US and JAP since 1960 GENRISK-T (4.4 M ) - genetic influence on the risk of radiation induced thyroid cancer GENEPI-ENTB2 (1.5 M ) - tissue bank for use in studies of the genetic determinants of individual radiosensitivity GENEPI-lowRT (1.8 M ) influence of genetic factors on individual radiosensitivity

Epidemiology Integrated Project SOUL - Southern Urals cohorts (12 M ) Cohorts o Mayak (external, plutonium) o Techa River (external, strontium) Effects o cancer incidence o cancer mortality o non cancer diseases Collaboration o RF, US and EU o Opportunities to broaden

Epidemiology - STREPS ALPHA RISK exposures to α radiation (4.4 M ) Cohorts o U miners o domestic radon o fuel cycle workers (U, Pu) GENE RAD RISK role of genetic susceptibility and radiation exposure in breast cancer (2 M ) RACE cardiovascular disease in breast cancer patients treated with radiotherapy (1.4 M )

Medical Uses of Radiation CT (3.1 M ) optimisation and justification of CT for a wide range of clinical applications including cardiac, interventional and paediatric good practice guidelines SENTINEL (0.7 M ) optimisation and justification of new and emerging imaging techniques (excluding CT) in diagnostic and interventional radiology physical and clinical image quality criteria good practice guidelines

Radioecology and Protection of the Environment ERICA (3.9 M ) integrated approach to assessing and managing the impact of radiation on the environment PROTECT (0.6 M ) evaluation of the merits and practicability of different approaches for regulating protection of the environment FUTURAE (0.7 M ) evaluation of potential for establishing deeper and sustainable integration of European research on radioecology, in particular through a Network of Excellence

Emergency Management EURANOS (14 M ) emergency management and rehabilitation strategies handbooks on countermeasurs for agricultural and inhabited areas improved decision support system (RODOS) demonstration projects strategies for and guidance on rehabilitation user driven TMT Handbook (0.7 M ) - monitoring and treatment of populations exposed to malevolent uses or radiation or radioacative materials

Protection of the Workplace CONRAD (0.3 M ) network to maintain and enhance European competence in radiation protection dosimetry analysis of options for achieving deeper and sustainable integration of European research working groups on computational dosimetry, internal dosimetry, complex mixed radiation fields and occupational exposure in medical radiology

Further information links to reports of completed projects in FP5 http://www.cordis.lu/fp5-euratom/src/lib_finalreports.htm links to ongoing projects in FP6 http://europa.eu.int/comm/research/energy/fi/fi_pubs/article_1 186_en.htm G N Kelly, EC, DG Research george-neale.kelly@ec.europa.eu

7 th Framework Programme (EURATOM) (2007-2011/13) Nuclear Fusion Nuclear Fission and Radiation Protection management of radioactive waste reactor systems radiation protection infrastructures human resources and training

Underlying Principles Continuity with the FP6 Simplification reduce red tape IPR funding schemes reporting

Content Radiation Protection Quantification of risks for low and protracted exposures epidemiological studies understanding mechanisms Medical uses of radiation enhance their safety and efficacy (in diagnosis and therapy) through new methodological and technological developments achieve balance between benefits and risks

Content Radiation Protection (cont d) Emergency management and rehabilitation improve coherence through development of common tools and strategies demonstrate efficacy in operational environments Malevolent uses Complementary to EC Security programme Other topics (dosimetry, radioecology, natural ) more effective integration of national research activities

Budgetary Resources FP6 190 M for 4 years ( 50 M per year) o RP 50 M FP7 initial Commission proposal 394 M for 5 years ( 80 M per year) o single budget no subdivision for RP FP7 revised Commission proposal 287 M for 5 years ( 60 M per year)

Work Programmes and Calls WP under preparation adoption by Commission in December (subject to timely approval of FP and SP by Council and Parliament) First call in late 06 or early 07 First deadline probably second quarter of 07 WP to be updated annually

Funding Schemes Collaborative Projects Networks of Excellence Coordination and Support Actions Actions to promote and develop human resources and mobility

Funding Schemes (cont d) Collaborative projects Details still under discussion between COM/Council/EP Maximum of 50% contribution likely to the be the general rule with some exceptions Additional Cost Model will probably disappear

Funding Schemes (cont d) Reimbursement at 100% Coordination and support actions Training, career development Frontier research (ERC)

Draft Work Programme 2007 Undergoing inter-service consultation within the Commission Sent to Members of CCE Fission Committee and will be informally discussed in early November To be finalised in December subject to approval of Framework and Specific Programmes Content/Timing influenced, inter alia, by status of and expected outcome of ongoing from FP6 projects Indicative budget 52 M

Quantification of risk for low and protracted exposures Non cancer effects, especially cardio- and cerebro-vascular diseases One or more Collaborative Project/s Feasibility of establishing a prospective cohort of medically exposed children A Support Action

Medical uses of radiation in diagnosis and therapy Reducing patient exposure Acquisition of key information for sound and scientifically based judgements on use of existing and emerging imaging techniques Quality criteria Synergy through networking Broadly applicable methodologies for assessing and reducing doses to peripheral tissues in therapy One or more Collaborative Project/s and/or Coordination Action/s

Emergency Management and Rehabilitation Optimising the design of monitoring systems o Develop methodology for optimising the design of monitoring systems at national or regional levels to better exploit state of the art decision support systems for emergency management (ie, to achieve more timely and better quality decisions) A collaborative project

Supporting infrastructure Data bases and tissue banks Design, refurbish, construct, operate and/or provide access to key data-bases or tissue banks for use in radiation protection research One or more Collaborative Project/Coordination Action or Support Action Radiobiology infrastructures Assess status of radiobiology infrastructures in Europe and evaluate adequacy for low-dose risk research A Support Action

Actions supporting programme implementation and other activities Dissemination of programme results Contributing to strategic objectives, notably ERA Preparation of future activities One or more Support Actions

Work Programme 2008 and beyond? WP 2008 expected to focus on low dose risk research radiobiology and epidemiology WP 2009 as WP 2008 plus further research on medical uses of radiation Consideration to be given to NoE in fields of dosimetry and radioecology subject to outcome of FP6 projects