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Lama Al-Khoury, MD Clinical Assistant Professor Neurology Department Stroke Center University of California Irvine (UCI) Medical Center 101 The City Drive South Building 53, Room 225 Orange, California 92868 Tel. 714-4567637 Fax 714-4562333 lalkhour@ uci.edu 1. SCHOOL AND RESIDENCY University Major Degree &Year American University of Beirut, Beirut, Lebanon Chemistry Bachelor of Science (B.S.), 1990 American University of Beirut Medical School Medical Doctor (M.D.), 1994 Medical Institution Residency/Fellowship Specialty&Year American University of Beirut MC, Beirut, Lebanon Internal Medicine Internal Medicine:1994-7 University of Arkansas MC, Little Rock, AR Neurology Neurology: 1997-2001 University of California San Diego (UCSD) Stroke Stroke: 2001-3 University of California San Diego (UCSD) Cerebrovascular Imaging 2003-2004 2. CURRENT PROFESSIONAL APPOINTMENTS AND CLINICAL RESPONSIBILITIES ACADEMIC APPOINTMENTS:: I) Faculty at the University of California Riverside (currently): a. Clinical Associate Professor at Dept. of Neurology (Aug 29, 2016-current) b. Program Director of Stroke c. Areas of expertise: Stroke and Headache Medicine II) Faculty at the University of California Irvine(previously): (Oct 2009-Aug 28, 2016) RESPONSIBILITIES: Clinical: Attending on Stroke and Headache clinics Teaching: supervision and teaching medical students, and residents Research!1

3. PUBLICATIONS 1. Resolution of chronic migraine headaches with intrathecal Ziconotide: a case report. Sachin Narain,, Lama Al-Khoury, Eric Chang.. Journal of Pain Research 2015:8 603 606 2. Book chapter Prevention of Ischemic Stroke : Al-Khoury L, Abcede HG, Jain V, Fisher M. ASPC Manual of Preventive Cardiology by Nathan D. Wong, Ezra A. Amsterdam, MD; and Roger S. Blumenthal. ASPC the American Society for Preventive Cardiology. 3. Case report abstract submitted to the 2015 AAN meeting: entitled Pineal Apoplexy With Cerebral Infarction, American Academy of Neurology 67th Annual Meeting, April 18 to April 25, 2015 4. Predictive Risk Factors of In-Hospital Mortality Following Acute Stroke in the United States: Data from the Nationwide Inpatient Database, 2006-2010 (P02.015). Nassim Naderi, Hermelinda Abcede, Lama Al-Khoury, Tahseen Mozaffar and Vivek Jain. 5. Book chapter: Intravenous Thrombolysis. The stroke reference book: Stroke: Pathophysiology, Diagnosis and Management, 5th Ed. Mohr, Wolf, Grotta. 2011. 6. 2005: book Chapter Community Experience with IV Thrombolysis. Thrombolytic Therapy for Stroke ; La2 nd Edition; Lama Al-KhourPatrick Lyden. Humana Press. 7. 2005: Assessment of Brain Perfusion in Stroke Patients with Echo Contrast Enhanced Transcranial Ultrasound: Preliminary Results. Academic Radiology, Volume 12, Issue 5 8. 2005: Prospective reliability of the STRokE DOC Wireless/Site Independent Telemedicine System. Neurology 2005; 64:1058-1060. 9. March 2004: book chapter: Intravenous Thrombolysis. Harcourt publishers March 2004 in the reference stroke book: Stroke: Pathophysiology, Diagnosis, and Management, 4 th Ed. Mohr, Choi, Grotta, Weir, Wolf, Eds. 10. 2004: Neuroprotection for Ischemic Stroke: Two Decades of Success and Failure The Journal of the American Society for Experimental Neurotherapeutics, volume 1, issue 1, page 36-45. 11. 2004: book chapter Emerging Therapies for Acute Ischemic Stroke published in the Blue Book of Practical Neurology: Prevention and Treatment of Acute Ischemic Stroke ; editors: Kasner and Gorelick; publishers: Butterworth-Heinemann, Boston.!2

12. Jan 2004: poster abstract Prospective Reliability and Validity of the Stroke Team Remote Evaluation Using a Digital Observation Camera (STRokE DOC) Wireless/ Site Independent Telemedicine Consultation Using the NIHSS and mnihss published in the journal Stroke in January 2004, page 294, poster 212. 4. MEDICAL BOARDS AND PROFESSIONAL MEMBERSHIP A. ABPN Board Certification in Neurology B. UCNS Board Certification in Headache Medicine 2014 C. American Academy of Neurology (member) D. American Heart Association (member) E. American Headache Society (member) F. International Headache Society (member) 5. RECENT RECOGNITIONS Top doctors-castle Connolly 2012, 2013, and 2015, posted in the OC magazine 6. LECTURES, CONFERENCES LED, AND PRESENTATIONS: a) I recently/newly joined UCR: I expect to continue providing lectures, grand rounds, and didactics, to academic groups/subspecialties at UCR, to residents and medical students, and to the community. b) Prior to joining UCR (end of Aug 2016) I alternated in leading stroke conference Mondays every 4-5 weeks c) Invited lecturer at the UCI Stroke Symposium 2012, 2014, 2015, most recently In Oct 2015 Secondary Stroke Prevention: What is Maximal Treament d) Invited lecturer at community hospitals to lecture at grand rounds on Stroke and Headache (List may be provided if needed), most recently on Feb 25th, 2016 to St Vincent Medical Center in Los Angeles. Secondary Stroke Prevention e) Lectures/ didactics on topics of Stroke and Headache to the medical students at UCI f) Lectures/didactics on topics of Stroke and Headache to the residents at UCI. g) Lectures/ didactics on Stroke to the Rehab fellows at UCI. h) Lectures/ didactics on Headache to the Pain fellow at UCI. 7. CURRENT CLINICAL RESEARCH Current Research: a. Principal Investigator at UCI: "Post-Treatment Blood Pressure and Outcomes In Acute Ischemic Stroke Treated with Endovascular Recanalization: A Retrospective study". 2014-Aug 2016 (In the process of analyzing the data)!3

b. Principal Investigator: An Open-Label Trial of Cilostazol in Preventing Progression of Cerebral Microbleeds in Mixed Cerebrovascular Disease. Study closed Aug 2016. c. Co-investigator: 2015: Solitaire FR With the Intention For Thrombectomy as Primary Endovascular Treatment for Acute Ischemic Stroke (SWIFT PRIME) Clinical Trial d. Trevo Device Registry. Sub-investigator at UCI (till Aug 2016). e. Co-investigator with PI Dr. Fisher: clinical trial: SOCRATES Acute Stroke Or Transient Ischemic Attack Treated with Aspirin or Ticagrelor and Patient Outcomes Previous older Research: a) August 2003-Oct. 2004: Principal Investigator (UCSD): Reliability and Validity of MRI in Detection of Intracranial Hemorrhage. b) 2003-2004: Sub-investigator in the core studies of the NIH SPOTRIAS grant: c) Intravascular Thrombolysis plus Hypothermia for Acute Treatment of Ischemic Stroke d) Stroke Team Remote Evaluation Using a Digital Camera Evaluation ( STROKE DOC ) e) Visualization of the Cerebral Arterial Circulation Using IMAGENT Contrast Enhanced Transcranial Doppler. f) 2001-2003: Sub-investigator in Intravascular Cooling in the Treatment of Stroke (ICTuS). g) 2001-2004: Sub-investigator in Brain perfusion using Ultrasound with Contrast Agent. h) 2001-2004: Sub-investigator in Atorvastatin as Prevention of Cerebrovascular Events in Patients With a Previous TIA of Stroke (SPARCL). i) 2001-2002: Sub-investigator in Siblings in Ischemic Stroke Study (SWISS). j) 2001-2002: Sub-investigator in Plasminogen Activator Plus YM872 or Tissue Plasminogen Activator Plus Placebo (ARTIST) in Acute ISCHEMIC Stroke. k) 2001-2003: Sub-investigator in Pilot Trial of TNK-TPA in Acute Ischemic Stroke. l) 2001-2003: Sub-investigator in Abciximab In Acute Ischemic Stroke (Reopro) m) 2001-2003: Sub-investigator in Warfarin vs. Aspirin for Symptomatic Intracranial Disease (WASID). n) 2001-2004: Sub-investigator in Management of Atherothrombosis with Clopidogrel in High-Risk Patients with Recent Transient Ischemic Attack or Ischemic Stroke (MATCH). o) 2002-2004: Sub-investigator in A Randomized, Double Blind, Placebo- Controlled Trial to Evaluate the Efficacy, Safety, Tolerability/ Pharmacokinetic/ Pharmacodynamic Effects of a Targeted Exposure of Intravenous Repinotan in Patients with Acute Ischemic Stroke.!4

Neurology References: Sam Ghostine, MD Associate Clinical Professor of Neurosurgery Chief of Neurosurgery UC Riverside SOM Riverside, CA Claudia Munoz, MD Assistant Clinical Professor of Neurology Director of Epilepsy UC Riverside SOM Riverside, CA Dr Neal Hermanowicz, M.D. Clinical Professor of Neurology UCI School of Medicine 100 Irvine Hall Irvine, CA 92697 nhermano@uci.edu 949-824-1047 Mark Fisher, MD Professor of Neurology UCI Medical Center 101 The City Drive South Shanbrom Hall, Room 121 Orange, CA 92868 mfisher@uci.edu 714.456.6856!5

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