Optimal repair of acute aortic dissection

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Optimal repair of acute aortic dissection Dept. of Vascular Surgery, The 2nd Xiang-Yale Hospital, Central-South University, China Hunan Major Vessels Diseases Clinical Center Chang Shu Email:changshu01@yahoo.com

Clinical Materials July, 2002 Feb, 2014 1057 Patients: Male: 695, Female: 362 Age: 19-86; Mean age: 51.2 Acute phase ( less than 2 weeks): 776 cases(2 hours-2weeks) Sub-acute and chronic phase (more than 2 weeks): 281 cases ( the longest history is 16 years)

Complicated acute aortic dissection Involving aortic arch: 137 cases AD associated with Marfan syndrome: 34 cases Retrograde type A aortic dissection: 49 cases With severe ischemia of visceral arteries, peripheral arteries and paralysis: 117 cases AD with huge hemothorax: 53 cases

Clinical Results Technically success: 99.9%(775/776) 6 cases died before TEVAR Recovered uneventfully: 749(96.5%) Peri-TEVAR complications (endoleak, respiratory distress, renal insufficience, et al.): 29(3.7%) Late complications (new entry tears, endoleak, migration, et al.):35 (4.5%) Fatal cases: 9 (1.2%, including the 5 cases died before TEVAR)

Endovascular strategy for aortic arch diseases Debranch LSA with stent-graft and/or PDF occluder Double Chimney technique Chimney technique for LCCA/LSA Hybrid technique Fenestrated technique 97 6 49 24 2

Complication Peri-operative complication rate: 3.7% Endoleak: 17(secondary TEVAR was performed, 14 stopped, 3 continued) Subclavian steal syndrome: 2 (surgery for 1, 1recovered spontaneously) Ischemia of the SMA and renal artery: 6 (conservative therapy for 5, 1 needed a stent) Respiratory distress: 4 (conservative treatment)

Complication Fatal cases: 9 (5 died before TEVAR) Myocardial infarction: 2 Cerebral infarction: 1 Respiratory failure: 1

Follow-up The mean duration of follow-up: 31.2months (1~ 139 months), True lumen enlarged, reduced of the false lumen, thrombosis fill in it : 739/776 Late complications happened: 33 19 new entry tears in distal aorta 2 stent-graft migration 6 distal false lumen dilated and formed aneurysm 3 unilateral renal atrophy 3 type A aortic dissection

Huge Aneurysmal Dissection Ruptured Contained Female, 74 years, Bp: 60/40, Heart rate:112/min

In order to transfer the second stent-graft, we have to use the balloon to pull the first stent-graft down

Aneurysm combined with dissection The patient is 163 cm high, but 115 K weight, severe chest pain

Marfan associated with AAD

The female, 39 years old. CT angiography detected chronic type B aortic dissection. Had been given Bentall before, Her son, 18 years old, acute dissecion: the CTA of him

We have done TEVAR for the son, no complications happened peri-evar One year later, the patient recovered well with thrombosis in the false lumen and aortic remodeling. CTA after TEVAR

Bentall technique was performed for the mother 3 years ago

Replacement of aortic root and valves was performed 3 years ago. Abrupt severe back pain was encountered caused by TBAD.

The aortic dissection in the descending aorta was occluded with remodeling of related distal aorta. Two weeks after TEVAR

4 years after TEVAR

Pre-TEVAR 2 weeks after 4 years later comparison Continuous dilatation also happened in abdominal aorta and bilateral iliac arteries.

MFS associated with puerperal state A female,29 years old, suffered from abrupt severe back pain 1 week after caesarean section. The primary entry tear located at the orifice of the LSA

MFS associated with puerperal state 1 month later, the patient recovered well without any symptoms. However, CT angiography detected mild contrast in the false lumen, and the patent false lumen communicated with LSA.

13 months later, CTA The left carotid artery was reconstructed with the chimney stent-graft. No endoleak continued!!

MFS associated with dissection and pregnancy

A 23-year-old female, gestated for 36 months. Widen mediastinum was found by chest X-ray. And CT angiography confirmed chronic type B aortic dissection. No signs of threatened labor.

Caesarean section was performed followed on emergent TEVAR. The patient recovered well, and the infant was healthy. No complication happened!

The whole lucky family

Retrograde type A AD with entry tear in descending aorta

Retrograde type A AD

Retrograde type A AD

Retrograde type A AD on set 2 weeks later

Retrograde type A AD --postoperation

TEVAR for retrograde type A AD Emergent TEVAR also can be used Pre-TEVAR

Post-operation: 2 weeks later

Aortic arch Dissection treated by Chimney SG

Chimney SG Male 60 years old Hypertension for more than 20 years Abrupt chest and back pain for two days

LSA is involved in the aneurym. aneurym and dissection overlap. The true lumen is narrow.

TEVAR associated with chimney SG to reconstruct the involved left common carotid artery is the best way to treat it.

Bi-chimney technique used in AD

A 50y male, suffered from abrupt chest and back pain. The primary entry tear was unclear in CT scans. Angiography indicated a typical non- A-non-B aortic dissection involve aortic arch. The primary entry tear was between the orifices of innominate artery and LCA.

Bi-chimney technique was used. Two Fluency stent-grafts were used to reconstruct IA and LCCA. The LSA was covered. The patient recovered well, without any complications. Until now, several cases have received bi-chimney technique in our hospital, short-term result is acceptable, no techniquerelated complications happen, but long-term result is unclear.

The patient recovered well, without any serious complications

AAD with mal-perfusion syndrome

Mal-perfusion of distal aorta There is no contrast in the distal abdominal aorta

The true lumen is completely compressed by the false lumen. Mal-perfusion of distal aorta

Mal-perfusion of distal aorta

Post-operation Post-TEVAR, the patient recovered well.

TBAD with renal failure

TBAD with renal failure TBAR with renal failure: The reason of acute renal failure should be distinguished: ischemia of RA. others disease, such as kidney tubules impairment.

TBAD with renal failure A patient with abrupt renal failure caused by acute TBAD

The orifice of left renal artery could not be found. The renal artery was originated from true lumen, but the orifice was narrow caused by compression. TBAD with renal failure

4 months after operation TBAD with renal failure

4 months after operation. The right renal was atrophied, but the left one and renal function recovered well. TBAD with renal failure

AAD with Acute Paraplegia

AAD with Acute Paraplegia Three patients with abrupt paraplegia was caused by ischemia of arteriae lumbales and arteriae intercostales. Emergent TEVAR was performed 1-9 hours after paraplegia. Drainage of CSF Stosstherapy with adrenal cortex hormone Rise up the BP: 140/80 Anticoagulation

The patient had been given Emergency TEVAR

AAD with Acute Paraplegia Myodynamia gradually recovered 4-24 hours after operation. When discharged 4-12 weeks after operation, the patients can walk by himself. But one patient need a catheter to release dysuria untill one year later.

Treatment of AD involving celiac artery

AD involved Visceral Arteries

The entry tear closes to the celiac artery. Visceral arteries were involved by AD.

Accurately deployment of the stent-graft was key point. The bottom of the stent-graft was deployed next to SMA. A short stent-graft was appropriate to exclude the AD and prevent paraplegia simultaneously. No visceral ischemia happened!!

AD involved visceral arteries The patient received aortic arch replacement previously. A new AD happened, involved the visceral arteries. The celiac artery was originated form the false lumen

The celiac artery was originated from the false lumen, and the entry tear was next to SMA.

Pre- Comparison Post-

TEVAR+PDA occlude

Familial AD + aberrant subclavian artery

Familial AD + aberrant subclavian A A 37-year-old female Her brother died several days before because of acute AD.

familial AD + aberrant subclavian artery

familial AD + aberrant subclavian artery

familial AD + aberrant subclavian artery

PDA occlude for type II endoleak AD related LSA Chimney tenique should be used

2 weeks after TEVAR, no type II endoleak lasted.

The apply of the distal restrictive bare stent A male, 66-year-old, encountered abrupt back pain. CT angiography indicated typical type B aortic dissection.

The distal restrictive bare stent With the distal restrictive bare stent technique, the distal thoracic aorta remodeling well.

Conclusion Most of the acute aortic dissection can be treated by TEVAR, Some Type A aortic dissection can also be treated by TEVAR; Some complicated acute TBAD can be treated endoluminally with advanced surgical skill and some assistant techniques: chimney, fenestration, branched stent-graft, hybrid-operation etc. It s conceived that Almost all aortic dissection can be treated with TEVAR in the future!

Thank you very much and welcome to the Second Xiang-Yale Hospital