Schedule of Accreditation issued by United Kingdom Accreditation Service 2 Pine Trees, Chertsey Lane, Staines-upon-Thames, TW18 3HR, UK

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Schedule of ccreditation United Kingdom ccreditation Service 2 Pine Trees, Chertsey Lane, Staines-upon-Thames, TW18 3HR, UK ccredited to Laboratory locations: Gavenny Court Brecon Road bergavenny Monmouthshire NP7 7RX Contact: Quality Manager Tel: +44 (0)1873 856688 Fax: +44 (0)1873 858984 E-Mail: labservices.info@synlabuk.com below s covered by the organisation and their relevant activities details ctivity code ddress Gavenny Court Brecon Road bergavenny Monmouthshire NP7 7RX Local contact Quality Manager Tel: +44 (0)1873 856688 Fax: +44 (0)1873 858984 Email: labservices.info@synlabuk.com Drugs of abuse analysis Quality Management Site activities performed away from the locations listed above: details ctivity code Commercial premises, Offices Local contact Quality Manager Specimen collection ( Hair, Saliva, Urine) B Tel: +44 (0)1873 856688 Fax: +44 (0)1873 858984 Email: labservices.info@synlabuk.com ssessment Manager: HM1 Page 1 of 11

Schedule of ccreditation United Kingdom ccreditation Service ccredited to DETIL OF CCREDITTION BODY FLUIDS, HIR ND PLSM Documented In-house Method Hair Presumptive Screening for Screening method using ELIS (enzyme immunoassay) mphetamines Benzoylecgonine, Cannabis, Barbiturates, Benzodiazepines, Opiates Ketamine, Phencyclidine, Method 9.0155 Oral fluid extracted from Quantisal collection kit Presumptive Screening for Screening method using CEDI immunoassay mphetamines Benzoylecgonine Cannabis Barbiturates, Benzodiazepines Opiates Method 9.0135 Method 9.0130 Method 9.0128 Method 9.0131 Method 9.0132 Method 9.0129 Method 9.0133 Urine Presumptive Screening for Screening method using DRI assay lcohol Method 9. 0108 Urine dulteration tests: Creatinine ph Specific Gravity Method 9.0117 using colourimetry Method 9.0116 using colourimetry Method 9.0119 using colourimetry ssessment Manager: HM Page 2 of 11

Schedule of ccreditation United Kingdom ccreditation Service ccredited to BODY FLUIDS, HIR ND PLSM Documented In-house Method Urine Presumptive screening for: using CEDI Immunoassay mphetamines Barbiturates Benzodiazepines Benzoylecogonine Buprenorphine Cannabis metabolites 6 Mono acetyl morphine Propoxyphene Phencyclidine (PCP) Opiates Methaqualone Presumptive screening for ethyl glucuronide (ethanol indicator and not as marker for alcohol abuse ) Presumptive screening for Ketamine Presumptive screening for Tramadol Presumptive screening for Lysergic acid diethylamide (LSD) Method 9.0103 Method 9.0104 Method 9.0105 Method 9.0106 Method 9.0113 Method 9.0102 Method 9.0114 Method 9.0110 Method 9.0111 Method 9.0107 Method 9.0109 Method 9.0112 Method 9.0124 using DRI Immunoassay Method 9.0125 DRI Immunoassay Method 9.0126 using Immunalysis Immunoassay Method 9.0118 using ELIS immunoassay ssessment Manager: HM Page 3 of 11

Schedule of ccreditation United Kingdom ccreditation Service ccredited to BODY FLUIDS ND TISSUES Documented In-House Methods using Urine of: mphetamine Benzoylecgonine 2-ethylidene-1,5-dimethyl-3,3- diphenylpyrrolidine (EDDP) 3,4-Methylenedioxyamphetamine (MD) 3,4-Methylenedioxy-Nethylamphetamine(MDE) 3,4-methylenedioxymeth amphetamine (MDM) Methamphetamine Method 12.0263 using solid phase extraction and LCMSMS Barbiturates: mylobarbital Butabarbital Pentobarbital Phenobarbital Secobarbital Method 12.0273 using Solid Phase extraction followed by LCMSMS Benzodiazepines: 7 amino nitrazepam 7 amino flunitrazepam Desmethyl Diazepam Diazepam Flunitrazepam Oxazepam Temazepam Method 12.0265 using hydrolysis followed by solid phase extraction and LCMSMS Buprenorphine Norbuprenorphine Method 12.0270 using hydrolysis and solid Phase extraction followed by LCMSMS Ketamine, Norketamine Method 12.0269 using Solid Phase extraction followed by LCMSMS 6-Mono-cetyl Method 12.0264 using Solid Phase extraction followed by LCMSMS ssessment Manager: HM Page 4 of 11

Schedule of ccreditation United Kingdom ccreditation Service ccredited to BODY FLUIDS ND TISSUES Documented In-House Methods using Urine of: 11-Nor 9-Tetrahydro Cannabinol-9-Carboxylic cid Method 12.0261 using hydrolysis followed by solid phase extraction, and LCMSMS S-Phenyl Mercapturic cid (SPM) Method 12.0303 by sample dilution and LC-MS-MS Confirmation and Quantitation of Opiates: ine Dihydrocodeine Method 12.0262 using hydrolysis followed by solid phase extraction, and LCMSMS Confirmation only of Opiates: Desmethylpapaverine Dihydromorphine Hydrocodone Noscapine Papaverine Pholcodine Thebaine Urine (unpreserved) Screening for; mphetamines; mphetamine Method 9.01574 using B Sciex Triple TOF with fast chromatography MDM MDE Methamphetamine Barbiturates; Phenobarbital Secobarbital Benzodiazepines; minonitrazepam minoflunitrazepam Flunitrazepam Hydroxyalprazolam ssessment Manager: HM Page 5 of 11

Schedule of ccreditation United Kingdom ccreditation Service ccredited to BODY FLUIDS ND TISSUES Urine (unpreserved) Screening for ; Benzodiazepines ; Lorazepam Method 9.01574 using B Sciex Triple TOF with fast chromatography Nordiazepam Oxazepam Phenazepam Temazepam Cannabinoids; Cannabinol THC THCC Cocainics; Benzoylecgonine Cocaethylene Cocaine Opiates; ine DHC 6-MM Opioids; Buprenorphine EDDP Fentanyl Norpropoxyphene o-desmethyltramadol Oxycodone Oxymorphone Propoxyphene Tramadol Psychoactives; mitriptyline Dihydronorketamine Gabapentin Ketamine Methaqualone Mirtazapine Norketamine ssessment Manager: HM Page 6 of 11

Schedule of ccreditation United Kingdom ccreditation Service ccredited to BODY FLUIDS ND TISSUES Urine (unpreserved) Screening for ; Method 9.01574 using B Sciex Triple TOF with fast chromatography Psychoactives ; PCP Pregabalin Quetiapine Cathinones; Cathinone Mephedrone KEDT Plasma from Blood Confirmation and Quantitation of: Clozapine Norclozapine Method 12.03510 using protein precipitation and LC-MS-MS Oral fluid (extracted from Quantisal collection kit) of : mphetamines: mphetamine, Methamphetamine, MDM, MDE. Method 12.071 using sample dilution in buffer and LC-MS-MS ssessment Manager: HM Page 7 of 11

Schedule of ccreditation United Kingdom ccreditation Service ccredited to BODY FLUIDS ND TISSUES Workplace/ Chemical Tests Documented In-house methods Oral fluid (extracted from Quantisal collection kit) of : Benzodiazepines: lprazolam, Desmethyldiazepam, Diazepam, Flunitrazepam, Lorazepam, Oxazepam, Temazepam, Method 12.071 using sample dilution in buffer and LC-MS-MS Cocainics: Cocaine, Benzoylecgonine, Cocaethylene. Opiates: ine, Dihydrocodeine, 6Monoacetylmorphine, Synthetic Opioids:, EDDP. Other psychoactive substance; Ketamine, Norketamine. Mephedrone Propoxyphene, Norpropoxyphene. Tramadol ssessment Manager: HM Page 8 of 11

Schedule of ccreditation United Kingdom ccreditation Service ccredited to BODY FLUIDS ND TISSUES (Cont d) Documented In-house method Hair of: mphetamines: mphetamine MDM MDE Method 12.0285 By extraction and LC-MS-MS Benzodiazepines: Desmethyl Diazepam Diazepam Flunitrazepam Lorazepam Nitrazepam Oxazepam Temazepam Cocainics: Cocaine: Benzoylecgonine Cocaethylene Norcocaine Opiates: cetyl ine ine Dihydrocodeine 6 Monoacetyl Heroin Synthetic Opiods: Other psychoactive substance: Ketamine Nor-ketamine Mephedrone Propoxyphene, Nor-propoxyphene Tramadol Zolpidem ssessment Manager: HM Page 9 of 11

Schedule of ccreditation United Kingdom ccreditation Service ccredited to BODY FLUIDS ND TISSUES Chemical Tests Documented In-house method Whole Blood of drugs of abuse; mphetamine Method 12.0322 using LC-MS-MS Clonazepam Diazepam Flunitrazepam Ketamine Lorazepam Methamphetamine Methylenedioxymethampheta mine (ecstasy) Oxazepam Temazepam Nordiazepam Norketamine Whole Blood (Preserved) Detection and quantitation of drugs Benzoylecgonine(50 µg/l) Cocaine (10 µg/l) Delta-9-tetrahydrocannabinol (2 µg/l) Method 12.03200 using protein precipitation and LC-MS-MS Method 12.03210 using liquid extraction and LC-MS-MS Whole Blood (preserved) of drugs of abuse: mphetamine Method 12.0322 using LC-MS-MS Benzolyecgonine Clonazepam Cocaine Diazepam Flunitrazepam Ketamine Lorazepam Methamphetamine MDM 6-monoacetylmorphine ssessment Manager: HM Page 10 of 11

Schedule of ccreditation United Kingdom ccreditation Service ccredited to BODY FLUIDS ND TISSUES Chemical Tests: Documented In-house method Whole Blood (preserved) of drugs of abuse: Oxazepam Method 12.0322 using LC-MS-MS Temazepam Nordiazepam Norketamine Opinion and interpretation Documented In-house Methods Drugs of buse in Urine, Oral fluid (Quantisal) and Hair Opinion and interpretation; relating to consistency of results with declared medication Method 10.0602 opinions and interpretation Sampling - Hair Hair Collection for subsequent drug of abuse analysis - Saliva Saliva Collection for subsequent drug of abuse analysis Method 6.0702 Method 6.0701 based on European Laboratory Guidelines for Legally Defensible Workplace Drug Testing, Version 1, 2002, using the Quantisal Device B B -Urine Specimen collection for subsequent drug of abuse analysis Method 6.0703 based on European Laboratory Guidelines for Legally Defensible Workplace Drug Testing, Version 1, 2002 B END ssessment Manager: HM Page 11 of 11