Instructions and Helpful Information for D-5 Form. Preliminary Approval of Dissertation and Request for Oral Defense (D-5)

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Instructins and Helpful Infrmatin fr D-5 Frm Preliminary Apprval f Dissertatin and Request fr Oral Defense (D-5) 1. DEADLINES D-5 must be submitted t the UGS at least 3 WEEKS BEFORE the date f the defense r by the UGS deadline (whichever date is the earliest). The defense annuncement must cnfrm t the UGS frmat, and bth a hard cpy and an electrnic versin must be submitted t ensure full prcessing f yur defense request. Deadlines fr submissin f frms t the UGS are available at http://gradschl.fiu.edu/calendar-deadlines/ Submit frms t the Academic units well befre the deadline t allw sufficient time fr apprval and signatures. Ultimately, it is the student's respnsibility t make sure frms are received by the University Graduate Schl n time and that all deadlines are met. 2. CONTINUOUS ENROLLMENT REQUIREMENTS Dctral candidates are required t be enrlled in at least 3 dissertatin credit hurs in the term in which they submit D-5. D-5 frm will nt be prcessed withut prf f current enrllment. Further infrmatin regarding the UGS cntinuus enrllment plicies is available at: https://plicies.fiu.edu/files/783.pdf. 3. INSTRUCTIONS All infrmatin must be typed. The final examinatin cmmittee will cnsist f all members f the dissertatin cmmittee and any ther members f the Graduate Faculty as may be appinted by the Dean f the UGS. Type the names f the cmmittee members and btain their riginal signatures. If ne f the cmmittee members is unavailable t sign, he/she can give the Department Chair written authrizatin t sign n his/her behalf. It is expected that all cmmittee members will be present fr the dissertatin defense. It is pssible fr ne cmmittee member t attend via vide cnference r telecnference technlgy, hwever prir apprval must be btained frm the UGS thrugh an electrnic Petitin fr Exceptin t Graduate Requirements. Please cntact yur academic unit t initiate this prcess. Cmplete checklist and attach dcumentatin as needed. Prvide a cpy f yur class schedule t shw prf f current enrllment in graduate credit hurs: Access: my.fiu.edu > Chse the Student Tab > Under Academics chse Class Schedule in the drp-bx > Chse the arrw next t the drp-bx t cntinue > Chse the current academic semester t cntinue > Shw nly the enrlled classes and filter > Click File > Print Preview > Pull drp-bx which states Only the selected frame > Print the entire enrllment class schedule Attach authrizatin if ne f the cmmittee members has authrized the Department Chair t sign n his/her behalf. Prvide a hard cpy f the entire Dissertatin in standard UGS frmat. This hard cpy is typically used by yur academic deans t make any cntent suggestins they may have. Prvide an electrnic versin t the UGS f the same Dissertatin submitted with yur D5 in standard UGS frmat. This electrnic versin is used fr frmatting review. T submit yur electrnic versin, yu will receive instructins via email t uplad t Digital Cmmns nce yur D5 and pertinent dcuments are received by the UGS. Regarding UGS frmat guidance, please refer t Regulatins fr Thesis and Dissertatin Preparatin Manual available at: http://gradschl.fiu.edu/dcuments/manual_regulatins.pdf. Be sure t include the fllwing in the dissertatin cpy: page (unsigned). Be advised that yu must use ne f the dissertatin apprval page templates fund at http://libguides.fiu.edu/etd (see example signature page belw). Title Page (mandatry), Abstract (mandatry), Table f cntents (mandatry), List f tables (mandatry fr 5 r mre tables), List f figures (mandatry fr 5 r mre figures), References (mandatry), VITA (mandatry), Cpyright Page (ptinal), Dedicatin (ptinal), Acknwledgments (ptinal), Appendices (ptinal). Prvide a hard cpy f the Dissertatin Defense Annuncement in standard UGS frmat.

Annuncement must cnfrm t the UGS standard. (See Additinal Infrmatin belw and attached example.) Prvide an electrnic versin f the dissertatin defense annuncement t the UGS as a Wrd dcument. Send t ugs@fiu.edu Submit D-5 frm and required dcumentatin t Chair/Prgram Directr and the Dean f the Cllege fr apprval. Submit hardcpy frm t the UGS fr final apprval. 4. ADDITIONAL INFORMATION DISSERTATION DEFENSE ANNOUNCEMENT The annuncement shuld be prepared in accrdance with the template available n the next page and at: http://gradschl.fiu.edu/thesis-dissertatin/. It shuld include the date, time, and venue and shuld be n lnger than ne page. The abstract, part f the annuncement, shuld be written in a schlarly style apprpriate t the discipline. AFTER APPROVAL OF YOUR DEFENSE Dissertatin hard cpy Yu will receive an email instructing yu t pick up yur hard cpy dissertatin draft frm the UGS ffice. This email will als include cnfirmatin that yur defense was apprved. Dissertatin electrnic cpy After the frmatting review f the electrnic versin f yur dissertatin has been cmpleted, yu will receive feedback regarding frmatting edits via email. This email will cntain a Cmmn Errr Checklist with a list f frmatting edits that must be crrected. Furthermre, yu will receive a cpy f yur electrnic dissertatin file with the frmatting edits marked thrughut yur dcument. If yur GPA is belw 3.0, see yur academic advisr in rder t make a plan t raise yur GPA abve 3.0.; yu cannt graduate with a GPA belw 3.0. T check the status f yur frm, please lg n t my.fiu.edu, and check under the T D List Sectin. REMINDER: Yu must apply fr graduatin in the same semester in which yu anticipate graduating. Please refer t https://nestp.fiu.edu/ fr graduatin deadlines.

Flrida Internatinal University University Graduate Schl UNIVERSITY GRADUATE SCHOOL BULLETIN ANNOUNCEMENT Dctral Dissertatin Defense Abstract The Relatinship f Thymulin Activity, Immune Parameters f HIV Disease Prgressin and Substance Use in a Chrt f HIV Serpsitive Alchl and Drug Users by Carlin Rafie Zinc is essential fr the activity f thymulin, a thymic hrmne invlved in T-lymphcyte differentiatin and activatin. Zinc deficiency is widespread in ppulatins with HIV infectin, and HIV+ drug users are particularly susceptible t zinc deficiency and immune suppressin. This dissertatin explred the relatinship f zinc-bund active thymulin t plasma zinc, CD4+ and CD8+ cell cunt, the CD4+/CD8+ rati, and drug use in HIV-infected drug users. Zinc-bund active thymulin was assessed in plasma f HIV+ drug users wh were participating in a 30 mnth zinc supplementatin trial. Plasma frm 80 participants at the 12 mnth visit, and 40 f these same participants, randmly selected, at the baseline visit were assessed fr zinc-bund active thymulin levels using a mdificatin f the rsette inhibitin assay. Thymulin activity was directly assciated with CD4+ cell cunt (β =0.127, p = 0.002) and inversely assciated with ccaine use (β = - 0.908, p = 0.026; R 2 = 0.188, p = 0.019) independent f HIV viral lad, age, gender and antiretrviral use. An increase in thymulin activity was 1.4 times mre likely when the CD4+ cell cunt increased (OR = 1.402, 95%CI: 1.006 1.956), independent f change in viral lad, antiretrviral use, and age. Participants wh used ccaine cnsistently, were 7.6 times less likely t have an increase in thymulin activity (OR = 0.133, 95%CI: 0.017 1.061). There was a direct crrelatin between change in plasma zinc and change in zinc-bund active thymulin (r = 0.243, p = 0.13). Analysis f CD4+ cell cunt decline in 222 participants in the zinc supplementatin trial acrss the 30 mnths shwed that bth crack ccaine use and heavy alchl use accelerated CD4+ cell cunt decline. Thymulin activity is directly assciated with HIV disease prgressin, measured by CD4+ cell cunt, and is depressed with ccaine use independent f antiretrviral use and HIV viral lad. Ccaine and heavy alchl accelerate CD4+ cell cunt decline. The effect f ccaine n thymic utput requires further evaluatin as a mechanism fr the assciatin f ccaine use with faster HIV disease prgressin. Date: Nvember 24, 2017 Time: 10:00 a.m. Place: University Park, HLSII 556 Department: Dietetics and Nutritin Majr Prfessr: Dr. Marianna Baum

T: Dean Michael Heithaus Cllege f Arts, Sciences and Educatin This dissertatin, written by Jhn A. Smith, and entitled The Perceived Effects f Fast- Fd Cnsumptin n Bdy Weight f Miami, Flrida Cllege Students, having been apprved in respect t style and intellectual cntent, is referred t yu fr judgment. We have read this dissertatin and recmmend that it be apprved. Jane E. Garcia Jhn P. De Christpher F. Jnes Mary A. Brwn, Majr Prfessr Date f Defense: August 8, 2017 The dissertatin f Jhn A. Smith is apprved. Dean Michael Heithaus Cllege f Arts, Sciences and Educatin Andrés G. Gil Vice President fr Research and Ecnmic Develpment and Dean f the University Graduate Schl Flrida Internatinal University, 2017 ii

ALL INFORMATION MUST BE TYPED FLORIDA INTERNATIONAL UNIVERSITY UNIVERSITY GRADUATE SCHOOL Preliminary Apprval f Dissertatin and Request fr Oral Defense (D-5) Name PID [Last] [First] [Middle] Primary telephne E-mail Ed.D. Ph.D. Prpsed Oral Defense Date, Time and Place INSTRUCTIONS: This frm must be submitted t the UGS at least 3 weeks befre the prpsed date f the defense r the UGS filing deadline, whichever date is earlier. The final examinatin cmmittee will cnsist f all members f the dissertatin cmmittee and any ther members f the Graduate Faculty as may be appinted by the Dean f the UGS. Dissertatin Title My signature belw affirms that I have read the dissertatin and find it prvisinally acceptable. In additin, I attest that the defense annuncement is an accurate abstract f the dissertatin. Majr Prf. / C-Majr Checklist f items that student MUST attach t frm befre submissin t Unit and Deans fr apprval. Prf f current enrllment in dissertatin credit hurs If ne f the cmmittee members is unavailable t sign, he/she can give the Department Chair authrizatin t sign n his/her behalf. (Attach authrizatin) One hard cpy f the Dissertatin in standard UGS frmat One electrnic cpy f the Dissertatin ready fr uplading fr frmatting review One hard cpy f the Dissertatin Defense Annuncement in standard UGS frmat Cnfirm: An electrnic versin f the dissertatin defense annuncement in Wrd has been sent t ugs@fiu.edu PLEASE NOTE: T uplad the electrnic versin f yur dissertatin, yu will receive an email with instructins t submit thrugh Digital Cmmns nce yur D5 and pertinent dcuments are received by UGS. REQUEST MADE BY: Date Student APPPROVED BY: APPROVED BY: APPROVED BY: FOR OFFICE USE ONLY: Date Chair/Prgram Directr Date Dean f Cllege r Schl Date Dean f University Graduate Schl REVIEWED BY: Enrllment in dissertatin credit hurs GPA f at least 3.0 Revised 02/18