RESPIRATORY VIRUS SURVEILLANCE REPORT

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RESPIRATORY VIRUS SURVEILLANCE REPORT Week Ending January 20, 2018 Wisconsin Department of Health Services Division of Public Health Bureau of Communicable Diseases Communicable Diseases Epidemiology Section https://www.dhs.wisconsin.gov/dph/bcd.htm dhsdphbcd@dhs.wi.gov

WISCONSIN DIVISION OF PUBLIC HEALTH RESPIRATORY VIRUS SURVEILLANCE REPORT WEEK ENDING January 20, 2018 INFLUENZA LIKE ILLNESS (ILI) ACTIVITY REGION V OF US (WI, MN, IL, MI, OH, IN) STATE OF WISCONSIN ILI: HIGH LEVELS ILI: MODERATE LEVELS UNITED STATES ILI: BELOW BASELINE ILI: INSUFFICIENT DATA AT-A-GLANCE: INFLUENZA-ASSOCIATED Weekly Respiratory Report Description PEDIATRIC DEATHS REPORTED: Predominant Virus of the Week: Week 3 (2018) October 1, 2017 to present Wisconsin 0 0 Nationwide 7 37 Influenza A/H3N2 CURRENT ALERTS: Influenza activity continues to increase statewide. 646 flu-associated hospitalizations were reported this week. RSV activity continues to be high statewide. For National US influenza surveillance statistics visit: http://www.cdc.gov/flu/weekly/ Page 2

Number of positive detections % Positive by PCR WISCONSIN LABORATORY SURVEILLANCE FOR RESPIRATORY VIRUSES BY PCR Wisconsin positive influenza results and subtypes by PCR A (unknown subtype) A (H3N2 seasonal) A (H1N1) A (H3N2v) 2,000 B (unknown subtype) B (Victoria) B (Yamagata) Influenza % positive 6 1,600 1,200 800 400 5 4 3 2 1 0 9/2 9/30 10/28 11/25 12/23 1/20 2/17 3/17 4/14 5/12 6/9 7/7 8/4 9/1 9/29 Cumulative number of positive influenza PCR tests by subtype September 3, 2017 to present Influenza A: 94% Influenza B: 6% A (2009 H1N1) A (H3N2) A (Unknown) B (Victoria) B (Yamagata) B (Unknown) Total positive (n) 65 1057 4939 4 47 336 6448 % of total positive 1% 16% 77% 1% 10 Total Page 3

% Positive by PCR (3-week moving average) WISCONSIN LABORATORY SURVEILLANCE FOR RESPIRATORY VIRUSES BY PCR Trends in respiratory virus activity by PCR 3 3 2 2 1 1 on January 20, 2018 Influenza RSV hmpv - - Rhino-Entero Adenovirus Parainfluenza - - Coronavirus Respiratory virus Positive (n) Positive (%) Influenza A Influenza B H3N2 2009 H1N1 Unknown Victoria Yamagata Unknown Influenza 5125 1755 34.2% 139 10 1487 1 9 109 Respiratory virus Positive (n) Positive (%) Parainfluenza 1 Parainfluenza 2 Parainfluenza 3 Parainfluenza 4 Parainfluenza 1088 13 1.2% 9 1 3 0 Respiratory virus Positive (n) Positive (%) CoV 229E CoV OC43 CoV NL63 CoV HKU1 Coronavirus (CoV) 519 22 4.2% 0 8 8 6 Respiratory virus Positive (n) Positive (%) RSV 1907 252 13.2% Human metapneumovirus 1111 40 3.6% Rhino-enterovirus 1047 36 3.4% Adenovirus 519 2 0.4% Page 4

% Positive by antigen detection Average % ILI WISCONSIN STATE SUMMARY Influenza rapid antigen tests RSV rapid antigen tests Influenza-like illness (ILI) Positive (n) Influenza A Influenza B Total % Positive Positive (n) % Positive ILI % Baseline Threshold 3872 1088 85 1173 30.3% 305 81 26.6% 4.4% 2.4% 3.6% ILI activity trend analysis 8% 7% Average % ILI Baseline Threshold 3 per. Mov. Avg. (Average % ILI) 6% 4% 3% 2% 1% Influenza and RSV trend analysis RSV Influenza 3 per. Mov. Avg. (RSV) 3 per. Mov. Avg. (Influenza) 5 4 4 3 3 2 2 1 1 Page 5

Influenza-associated hospitalizations, cumulative (n) Average % ILI (3-week moving average) WISCONSIN STATE SUMMARY ILI activity trend analysis by influenza season, Wisconsin 7% 6% 4% 3% 2% 1% 2013-14 - - 2014-15 2015-16 2016-17 2017-18 40 42 44 46 48 50 52 2 4 6 8 10 12 14 16 18 20 Influenza season week Influenza-associated hospitalizations, Wisconsin Electronic Disease Surveillance System September 1, 2017 to present Total Influenza subtype Required Age group Admitted Postpartum reported A (2009 A A Not mechanical Pregnant (years) B to ICU ( 6 weeks) (n) H1N1) (H3N2) (Unknown) reported ventilation <1 28 1 3 22 0 2 5 1 0 0 1-4 44 1 1 33 4 5 6 3 0 0 5-17 60 1 4 32 2 21 10 1 0 0 18-49 327 7 35 230 17 38 49 11 21 4 50-64 599 24 84 419 41 31 91 32 0 0 65+ 2138 21 280 1641 95 101 235 61 0 0 Total 3196 55 407 2377 159 198 396 109 21 4 Reported cumulative influenza-associated hospitalizations by influenza season, Wisconsin 3750 3000 2250 1500 750 2017-2018 2016-2017 2015-2016 2014-2015 2013-2014 0 44 45 46 47 48 49 50 51 52 1 2 3 4 Influenza season week Page 6

% Positive by antigen detection Average % ILI NORTHEASTERN REGION Influenza rapid antigen tests RSV rapid antigen tests Influenza-like illness (ILI) Positive (n) % Positive Positive (n) % Positive ILI % Baseline Threshold Influenza A Influenza B Total 1019 307 11 318 31.2% 83 22 26. 7. 2.6% 4. ILI activity trend analysis 8% 7% Average % ILI Baseline Threshold 3 per. Mov. Avg. (Average % ILI) 6% 4% 3% 2% 1% Influenza and RSV trend analysis RSV Influenza 3 per. Mov. Avg. (RSV) 3 per. Mov. Avg. (Influenza) 5 4 4 3 3 2 2 1 1 Page 7

% Positive by antigen detection Average % ILI NORTHWESTERN REGION Influenza rapid antigen tests RSV rapid antigen tests Influenza-like illness (ILI) Positive (n) Influenza A Influenza B Total % Positive Positive (n) % Positive ILI % Baseline Threshold 996 287 21 308 30.9% 122 37 30.3% 17. 1.9% 3.2% ILI activity trend analysis 8% 7% Average % ILI Baseline Threshold 3 per. Mov. Avg. (Average % ILI) 6% 4% 3% 2% 1% Influenza and RSV trend analysis RSV Influenza 3 per. Mov. Avg. (RSV) 3 per. Mov. Avg. (Influenza) 5 4 4 3 3 2 2 1 1 Page 8

% Positive by antigen detection Average % ILI SOUTHEASTERN REGION Influenza rapid antigen tests RSV rapid antigen tests Influenza-like illness (ILI) Positive (n) Influenza A Influenza B Total % Positive Positive (n) % Positive ILI % Baseline Threshold 1703 436 48 484 28.4% 74 14 18.9% 5.4% 3.9% 6.1% ILI activity trend analysis 8% 7% Average % ILI Baseline Threshold 3 per. Mov. Avg. (Average % ILI) 6% 4% 3% 2% 1% Influenza and RSV trend analysis RSV Influenza 3 per. Mov. Avg. (RSV) 3 per. Mov. Avg. (Influenza) 5 4 4 3 3 2 2 1 1 Page 9

% Positive by antigen detection Average % ILI SOUTHERN REGION Influenza rapid antigen tests RSV rapid antigen tests Influenza-like illness (ILI) Positive (n) Influenza A Influenza B Total % Positive Positive (n) % Positive ILI % Baseline Threshold 154 58 5 63 40.9% 26 8 30.8% 2.1% 2.1% 3.2% ILI activity trend analysis 8% 7% Average % ILI Baseline Threshold 3 per. Mov. Avg. (Average % ILI) 6% 4% 3% 2% 1% Influenza and RSV trend analysis RSV Influenza 3 per. Mov. Avg. (RSV) 3 per. Mov. Avg. (Influenza) 5 4 4 3 3 2 2 1 1 Page 10

Percent Vaccinated SEASONAL INFLUENZA VACCINATION Cumulative percentage of Wisconsin residents who received 1 or more doses of influenza vaccine, 2017-2018 influenza season 10 9 8 7 Healthy People 2020 Goal: 7 6 5 4 3 2 2016-2017 Total Vaccinated: 3 This season so far: 32.36% Last season, by this week, 32.5 of the WI population was vaccinated against Influenza. 1 Data source: All influenza vaccination rates presented were calculated using data from the Wisconsin Immunization Registry (numerator) and Wisconsin population estimates (denominator). Influenza vaccine composition 2017-2018: The trivalent vaccines for use in the 2017-2018 influenza season contain the following: A/Michigan/45/2015 (H1N1)pdm09-like virus A/Hong Kong/4801/2014 (H3N2)-like virus B/Brisbane/60/2008-like virus (B/Victoria lineage) It is recommended that quadrivalent vaccines containing two influenza B viruses contain the above three viruses and: B/Phuket/3073/2013-like virus (B/Yamagata lineage) Page 11

Race Ethnicity Percent of residents vaccinated SEASONAL INFLUENZA VACCINATION Percentage of Wisconsin residents who received one or more doses of influenza vaccine, by age group and influenza season 10 9 2014-2015 2015-2016 2016-2017 2017-2018 8 7 6 5 4 3 2 1 Each season includes doses administered during the same time period (August 1 through May 3). Age group Percentage of Wisconsin residents who received one or more doses of influenza vaccine, by race and ethnicity and region, 2017-2018 influenza season Non-Hispanic Hispanic White Wisconsin Northeastern Southeastern Southern Western Northern Black Asian American Indian 1 2 3 4 5 6 7 8 9 10 Percent of residents vaccinated Page 12