Pediatric Wounds: Basic to Complex Addressing Wound Management, Pressure Injury & NPWT

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Pediatric Wounds: Basic to Complex Addressing Wound Management, Pressure Injury & NPWT Tamara M. Meeker, MSN, CRNP, NNP-BC The Children s Hospital of Philadelphia Philadelphia, PA Disclosure Information I have nothing to disclose Any mention of Trade names of certain products are for familiarity & example and are not intended to be an advertisement or a recommendation Any examples given are not an all inclusive list Objectives 1. Describe the optimal wound healing environment 2. Choose the appropriate wound dressing based on the understanding of general wound dressing categories coupled with knowledge of wound characteristics 3. Identify most common causes of pressure injury in the neonatal/pediatric populations 4. Explain ways in which pressure injury in the neonatal/pediatric populations can be prevented 5. Describe the use of negative wound pressure therapy in the pediatric population 1

Our Skin Quick Facts: Our largest organ system Functions Protection Barrier to infection, chemicals, UV radiation Metabolism Vitamin D Thermoregulation Sweating, excretion of waste, fluid regulation Receives sensory input Receives 1/3 of the body s circulating blood Our Skin Layers of the Skin Epidermis Avascular Five layers Stratum basale Stratum spinosum Stratum granulosum Stratum lucidum Stratum corneum Inner layer Outer layer 2

Dermis Thickest layer Highly vascularized Primarily collagen and elastin Houses nerve & sensory organs Houses sweat & sebaceous glands Made up of two layers Layer of the Skin Papillary Dermis-supplies O 2 to epidermis Reticular Dermis-structural support Layers of the Skin Subcutaneous Tissue Functions to support skin Two Layers: Adipose tissue-large blood vessels, nerves, insulation, protection, stores energy Fascia-fibrous connective tissue, separates and surrounds almost all structures Types of Wounds Acute-traumatic Surgical Pressure Chronic Venous ulcers Arterial ulcers Diabetic ulcers 3

Types of Wound Healing Superficial Primary intention Delayed primary intention Partial-Thickness Secondary intention Superficial Wound Healing 1 st degree burns Scrapes Contusions Shear/friction injury Heal themselves with proper intervention (keeping clean and dry) Primary Intention Surgical wounds Wound edges approximated w/ sutures or staples Usually close in 7 days Usually minimal to no scarring 4

Delayed Primary Intention Traumatic wounds Wound is left open and sutured later (4-7 days) when risk for infection is decreased Common when Wound is contaminated/high risk for infection Large amount of tissue loss Large amount of tissue tension Partial Thickness Wound Healing When there is loss of the dermal layer Refers to: Abrasions, skin tears, 2 nd degree burns, Stage II pressure injury Goal is to keep moist and clean and to eliminate the source of trauma Secondary Intention a.k.a. Contraction Full thickness wounds only Edges cannot be approximated due to massive tissue loss or nonviable wound edges Usually have high microbial content, slough, and necrosis 5

Stages of Wound Healing Regardless of the type of wound, all wounds must heal in the following pattern: Hemostasis/Coagulation Inflammation (1-10 days) Proliferation (3-28 days) Maturation/Epithelialization Remodeling (9 days - years) Neonatal / Pediatric Wounds Surgical Extravasation Injury Thermal Pressure injury Chemical injury Mechanical Heel Sticks Ostomy Tracheostomy G-tubes Incontinence-associated dermatitis Moisture associated dermatitis Factors Affecting Wound Healing in Pediatrics Protein-calorie malnutrition Impaired perfusion Decreased oxygenation Edema Infection Decreased epidermal:dermal cohesion Deficient stratum corneum Impaired thermoregulation Immature immune system Immature renal & hepatic systems Age / Gestational age Use of steroids Comorbidities Bioburden Malnutrition-Vitamins A, C & Zinc Immobility 6

Optimal Wound Healing Environment Reduce or eliminate causative factors Systemic support-blood, O 2, fluid, nutrition, +/or antibiotics Remove necrotic tissue or foreign body Eliminate infection Obliterate dead space Absorb exudate Maintain moist environment Protect from further trauma Protect from bacterial invasion Provide thermal insulation Wound Dressings-Facts Matching wound characteristics w/ dressing features is paramount to healing Moist wounds heal faster than dry wounds Dry wounds should be kept moist by dressing Wounds with heavy exudate should be dried by the dressing Change dressings when soiled- in just 5 min Staph epi can migrate through 5 layers of moist gauze (Cochrane Collaboration, 2008) Once a day cleansing as a minimum Foreign body left in wound bed by dressing will impede healing Wound treatment that has not shown improvement in 10-14 days MUST be changed Wound Dressing-Categories Primary-contacts wound directly Secondary-covers the primary dressing Occlusive-completely covers wound environment and keeps all moisture at wound Semi-occlusive-allows some O 2 and moisture vapor through dressing 7

Dressing Selection Criteria Protect the wound Facilitate atraumatic removal Minimal changes required Remain in place in a humidified environment Correct size Meets wound's needs Protects peri-wound skin Price & cost ***A dressing is only as good as the clinician who selects it*** (Ovington, 2001) Wound Dressing-Types Gauze Non-adherent contact layers Hydrogel Hydrocolloid Transparent Film Calcium alginate Hydrofiber Foam Skin Sealant Enzymes Negative Pressure Wound Therapy (Kim) Gauze Examples: 2x2, 4x4, packing NuGauze Wet-to-damp for debridement Dry for draining wounds Contraindications: Healthy granulating wounds Dry wound bed 8

Non-Adherent Contact Layers Examples: Telfa (not latex free) Adaptic White petrolatum impregnated gauze Xeroform gauze Superficial wounds Draining wounds Non-stick occlusion Intact incisions Contraindications: known sensitivity to product Examples: Amorphous (Carrasyn gel) Sheet gels (Vigilon) Hydrogel/Gels Partial-thickness wounds Necrotic or granulating wounds Dry wound beds Burns Keep bladder plates moist (Bladder exstrophy patients) Contraindications: Grossly infected wounds Stage IV pressure injury Hydrocolloid Examples: DuoDerm DuoDerm thin DuoDerm paste Prevention Partial thickness Full thickness Autolysis Ulcers with cavity (paste only) Contraindications: Infected wounds Stage IV pressure injury Wounds with significant depth 9

Transparent Films Examples: Tegaderm Op-site Partial thickness wounds Debride eschar Autolysis Prevention Allows exchange of O 2 Prevents penetration by bacterial or fluid Contraindications: Skin tears Moist wounds Infected wounds Examples: Kaltostat Sorbsan Calcium Alginate Draining wounds Hemostatic properties Contraindications: Dry wound bed Examples: Aquacel Aquacel Ag Hydrofiber Exudate absorption absorbent material that turns into a gel when in contact with exudate Silver ion products have antimicrobial properties Contraindications: Dry wound beds 10

Foams Examples: Hydrasorb Lyofoam Mepilex Mepilex Lite Partial thickness wounds Skin tears Full thickness wounds Donor sites Burns (1, 2 ) Contraindications: Heavily exudating wounds Skin Sealant Examples: Skin prep (contains alcohol) 3M Cavilon NoSting (no alcohol) Healthy, intact skin-protectant Prevent friction Perianal intact skin Under tape, adhesives, wafers Crust method for denuded skin Contraindications: Open skin Patients < 30 days old Enzymes Example: Collagenase Necrotic slough Contraindications: Eschar, unless scored Healthy, granulating wounds 11

Common Causes of Pressure Injury Conventional Pressure Injury Immature skin Compromised perfusion Sub-optimal nutrition Impaired mobility / paralysis Fluid retention / edema Moisture Long OR cases Medical Device-Related Catheter hubs Pulse ox probes CPAP masks Nasal cannulas Tracheostomies Occiput injury Casts / splints Endotracheal tubes Collars Pressure Injury Prevention Positioning aides: Gel pillows Fluidized positioners Pressure distribution mattresses Moisture management Floating the heels Foam product: Under hubs for IV catheters and PAL catheters Under central lines Under tracheostomy and gastrostomy tubes Under CPAP masks and cannulas At pressure points of collars, cast, splints Thank you for your attention! 12

Negative Pressure Wound Therapy Kimberly McIltrot, DNP, CPNP, CWOCN Johns Hopkins University School of Nursing Baltimore, MD Disclosure Information I am the Editor-in-Chief of the Journal of Pediatric Surgery Outcomes The learner will: Discuss three indications and contraindications of Negative Pressure Wound Therapy (NPWT) 13

Healing is a matter of time, but also a matter of opportunity ~Hippocrates Negative Pressure Wound Therapy (NPWT) An active wound management system that utilizes controlled negative pressure which is applied uniformly to the wound through an open cell foam or other interface dressing in a constant or intermittent fashion Maintain a moist wound environment Control exudate and odor Reduce edema, infection and pain Promote perfusion and granulation Provide wound contraction Reduce dressing changes and cost NPWT Indications Chronic wounds Surgical wounds Acute wounds Traumatic wounds Dehisced incisions Diabetic wounds Pressure injury Meshed grafts Partial thickness burns Retrieved from researchgate.net 14

NPWT Considerations Will symptoms be managed more effectively? What are wound dimensions and can NPWT be easily applied? Any contraindications? Will placement of tubing be a problem? If discharged home can they manage therapy at home? Can wound bed be prepared effectively? Is patient and family willing and able to consent? Henderson, et al (2010) NPWT Contraindications/Precautions Patient non-compliance Dressing retention Foam adherence Bleeding Pain Malignant wounds Mobility hazard Untreated osteomyelitis Non-enteric and unexplored fistulas Necrotic tissue and eschar present Therapies such as MRI, defib etc. Don t place on organs, nerves, blood vessels, anastomotic sites Therapy Guidelines Start and stop therapy at appropriate times 24 Hour continuous therapy Dressing changes 48-72 hours Wound measurements at initiation of NPWT and at least weekly Progress to closure products and therapies 15

Application Steps Perform wound bed preparation Possible dressing interface application Perform application of the NPWT dressing Initiate Therapy Unit Dressing removal Bridging and Y Connecting Wounds Bridging connects multiple wounds in close proximity to each other by a foam strip Bridging may be used to position the pad/tubing away from an undesirable area (e.g. Sacral area) Y connecting connects 2 separate systems to one Therapy Unit Image of bridging Retrieved from: https://www.youtube.com/watch?v=erg8vy49jq0 Troubleshooting Leak detected Blockage Low Battery Canister/tubing problems Difficult areas to apply NPWT What if NPWT doesn t work Retrieved from ostomyoutdoors.com 16

Thank You! Questions? References Boxall, S., Carville, K., Leslie, G., & Jansen, S. (2007). Treatment of anticoagulated patients with negative pressure wound therapy. International Wound Journal, doi: 10.111/iwj.12737.[Epub ahead of print] Henderson, V., Timmons, J., Hurd, T., Maloney, S., & Sabo, S. (2010). NPWT in everyday practice Made Easy. Wounds International, 1 (5), retrieved from http://www.woundsinternational.com Jones, S., Banwell, P., & Shakespeare, P. (2005). Interface dressings influence the delivery of topical negative-pressure therapy. Plastic Reconstructive Surgery, 116(4), 1023-1028. McIltrot, K. (2013). Wound management in neonates, children, and adolescents. N. Browne, L. Flanigan, C. McComiskey & P. Pieper Editors in Nursing Care of the Pediatric Surgical Patient 3 rd Ed. Jones and Bartlett Learning; Burlington, MA. 162-163. Mushin, O., Bogue, J., Esquenazi, M., Tocsano, N., & Bell, D. (2017). Use of a home bacuum-assisted closure device in the burn population is both cost-effective and efficacious. Burns, (16), 30346-1. doi: 10.1016/j.burns.2016.08.036. Webster, J., Scuffham, P., Stankiewicz, M. & Chaboyer, W. (2014) Negative pressure wound therapy for skin grafts and surgical wounds healing by primary intention. Cochrane Database Systematic Review, 10, doi: 10.1002/14651858.CD009261.pub3 17