Friday 2nd and 3rd March 2018

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REGISTER NOW! fungalupdate.org 13th Annual Fungal Update Meeting The Great Hall and Haberdashers Hall, St Bart's, London CPD Accreditation: Royal College of Pathologists - 11 credits Friday 2nd and 3rd March 2018 Chairs: Prof Tony Pagliuca, Kings College, London and Dr Tom Chiller, CDC, USA 1st Imaging and Respiratory Challenges in the Immunocompromised Workshop The Court Room,Haberdashers Hall, St Bart's, London Friday 2nd March 2018 Chairs: Dr Athar Haroon (Barts Health NHS Trust, London) and Dr Paul Pfeffer (QMUL, London) PROGRAMME

PROGRAMME - MAIN FUNGAL UPDATE DAY 1-2nd MARCH Antifungal Management in Haemato-Oncology: Real World Implementation 10:10 Non empirical management Dutch courage - Prof Nicole Blijlevens, Haemato-Oncology, Nijmegen 10:35 11:00 11:55 Pre-emptive management where it started - Prof Johan Maertens, Haemato-Oncology, Leuven Empirical management pre and post Brexit - Dr Andy Peniket, Haemato-Oncology, Oxford 11:25 11:55 GREAT HALL - TEA BREAK Radiology driven non empirical management Italian image(s) - Dr Marta Stanzani, Haemato- Oncology Bologna, Italy 12:20 Q&A GREAT HALL : Lunch and Sponsor Stands 12:40 13:55 Lunch served 13:10 13:40 Industry short presentations (3 x 8-min slots) Main Plenary Livery Hall, Haberdashers 13:55 14:25 Symposium (sponsored) Diagnostics and Therapeutics For Fungal Pathogens A New Dawn? 14:30 Antibody-based diagnostics and therapeutics for fungal infections - Dr Fiona Rudkin, Aberdeen, UK 14:55 Antibodies for Mucorales - Prof Ashraf Ibrahim, UCLA, USA 15:20 15:50 GREAT HALL TEA BREAK 15:50 16:15 Antibodies for Diagnostic Immuno PET/MR Imaging - Dr Chris Thornton, Exeter Pan fungal detection - Dr Daniel Poulain, Lille, France 17:00 Q&A 17:45-18:05 Charity Event (all donations to go to CRUSE bereavement care): A recital by the world-renowned Canterbury Cathedral Boys Choir in the historic parish church of St Bartholomew s the Great - ALL WELCOME Evening Educational Session and Meeting Dinner at The Crowne Plaza Hotel 19:30 19:50 Just-a-minute: Each speaker has a one-minute slot, BUT as per the just-a-minute format: to talk on the subject for 60 seconds without hesitation, repetition or deviation BSMM vs BMS vs ISHAM vs Fungal Update DINNER

PROGRAMME - MA I N FUNGAL UPDATE DAY 2-3rd MARCH Main Plenary Livery Hall Chairs: Prof Tony Pagliuca, Kings College, London and Dr Tom Chiller, CDC, USA Challenging Clinical Cases Court Room Chairs: Dr Rohini Manuel, Public Health England, London; Dr Jonathan Lambourne, Barts Health NHS Trust, London and Dr Tom Chiller, CDC, USA 09:55 Introduction from the Chairs 09:55 Introduction from the Chairs Fungi, the host response and human disease 10:00 Macrophages, TLR - BTK signaling and Aspergillus fumigatus - Dr Darius Armstrong- James, Imperial College, London 10:00 Case Study 1 Is that a yeast or a mould? Challenges in tissue transplantation Dr Rohini Manuel, Public Health England, London 10:25 Fungal suppression by human γδ T-cells in mucosal immunity and inflammation - Dr Neil McCarthy, QMUL, London 10:50 Keynote Lecture : Overview of immunity to fungal pathogens and human disease - Prof Stuart Levitz, USA 11:20 11:50 GREAT HALL TEA BREAK 11:50 Q&A Generic Antifungals and Novel Agents 10:40 Case Study 2 Where did that come from? Dr Jonathan Lambourne, Barts Health NHS Trust, London 11:20 11:50 GREAT HALL TEA BREAK 11:50 Case Study 3 Chasing mould around hospitals: clinical challenges in outbreak response and prevention Dr Tom Chiller, CDC, USA 12:05 Generic antifungal agents what do we need to know - Prof William Hope, Liverpool, UK 12:30 Novel agents in clinical trials a drug revolution? Dr Roger Bruggemann, Radboud UMC, Nijmegen 12:55 Q&A 13:10 Lunch served GREAT HALL : Lunch and Sponsor Stands 13:40 14:10 Industry short presentations (3 x 8-min slots)

Main Plenary Livery Hall, Haberdashers 14:10 14:40 Symposium (sponsored) 14:55 Keynote Lecture: NHS perspective on antifungals (generics), stewardship and CQUINs - Malcolm Qualie, Pharmacy Lead, Specialised Services, NHS England 15:25 Q&A 15:40 GREAT HALL TEA BREAK Resistance and Global Issues 16:00 HIV-associated cryptococcal meningitis: Effective and sustainable regimens for resource-limited settings - Prof Tom Harrison, St George s Hospital, London, UK 16:25 Resistance Update - Candida auris Resistance Update - Aspergillus sp., - Dr Tom Chiller, CDC, USA - Prof Paul Verweij, Center of Expertise in Mycology,Radboudumc/CWZ. 17:20 Q&A and Meeting Close

IMAGING AND INFECTION WORKSHOP The Court Room, Hab erdas hers Hal l Fri day 2nd March Chairs: Dr Athar Haroon (Barts Health NHS Trust, London) and Dr Paul Pfeffer (QMUL, London) 10:00 Welcome from the Chairs Session 1: Imaging and Respiratory Infection 10:10 X-Ray and CT of the Chest Utility and Limitations - Dr Stephen Ellis, 10:40 Imaging Lead St Bartholomew s Hospital, Barts Health NHS Trust Diagnostic Work-up in the Immunocompromised - Prof Jeremy Brown, Respiratory Lead UCL/ UCLH, London 11:10 The Future of Laboratory Diagnostics - Dr Lewis White, Principal Clinical Scientist, PHW, Cardiff 11:40 Q&A 11:50 GREAT HALL TEA BREAK 12:10 Stereotactic-Navigated Bronchoscopy for Biopsy of Lung Nodules from Cancer to Infection? - Dr Kelvin Lau, Cardiothoracic Lead, St Bartholomew s Hospital, Barts Health Trust 12:40 CT-PA Driven Management of Lung Nodules in Haemato-Oncology - Dr Claudia Sassi, Bologna, 13:10 Q&A GREAT HALL : Lunch and Sponsor Stands 13:25 14:15 Lunch served 13:10 13:40 Industry short presentations (3 x 8-min slots) Session 2 : Imaging of Complications and Novel Diagnostics 14:30 Imaging of Graft Versus Host disease - Dr Khawaja Shabuddin, GI Radiology, Barts Health NHS Trust 15:05 Infection in the Central Nervous System - Dr Gerry Thompson, Centre for Clinical Brain Services, Edinburgh 15:35 PET/MRI and PET/CT in Infection: Role of New Biomarkers for Molecular Imaging Dr Athar Haroon, Radionuclide Radiologist, St Bartholomew s Hospital, Barts Health NHS Trust 16:15 Q&A 17:45-18:05 Charity Event (all donations to go to CRUSE bereavement care): A recital by the world-renowned Canterbury Cathedral Boys Choir in the historic parish church of St Bartholomew s the Great - ALL WELCOME

Registration FUNGALUPDATE.ORG To attend Fungal Update 2018 the following fees apply. (These prices are inclusive of VAT) Standard 80 Standard with Accomodation and Dinner 175 Trainee 50 Trainee with Accomodation and Dinner 120 One Day Imaging and Infection Workshop 50 One Day Imaging and Infection Workshop Trainee 35 One Day Imaging and Infection Workshop plus Day 2 of Fungal Update 80 and 50 for Trainee If you have any questions, please contact Andy Cockayne using the following details: E: organisers@fungalupdate.org T: +44 (0) 1353 780 060