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Table Of Content Using Multidimensional Prognostic Indices(MPI)to improve costeffectiveness of interventions in multimorbid frail older persons.... 2 Summary... 3 Coordinator, Leader contact and partners... 5 Univerzita Karlova v Praze... 5 Karolinska Institutet... 5 European Union Geriatric Medicine Society... 5 Servicio Madrileño De Salud... 5 Universitätsklinikum Köln AöR... 5 Fundación Para La Investigación Biomédica Del Hospital Universitario Ramón Y Cajal... 5 Erasmus Universitair Medisch Centrum Rotterdam... 5 Centre Hospitalier Universitaire de Poitiers... 5 Outputs... 7 D01 - Web-based Management Information Tool... 7 D02 - Interim Report (technical + financial)... 7 D03 - Final Report (technical + financial)... 7 D04 - Dissemination Strategy... 7 D05 - Develop and publish project leaflet... 7 D06 - Internal and External Evaluation Reports... 7 D07 - Analysis report on the use of predictive rules in clinical decision making in community-dwelling older adults... 7 D08 - Report on the use of CGA-based MPI in improving cost-effectiveness of drug treatments in older individuals... 7 D09 - Report on the application of MPIs in different settings to improve the costeffectiveness of interventions.... 7 D10 - Report with recommendations... 7 Page 1/9

Using Multidimensional Prognostic Indices(MPI)to improve costeffectiveness of interventions in multimorbid frail older persons. JA2015 - GPSD [705038] START DATE: 01/02/2014 END DATE: 01/02/2017 DURATION: 36 month(s) CURRENT STATUS: Finalised PROGRAMME TITLE: Second Programme of Community action in the Field of Health 2008-2013 PROGRAMME PRIORITY: - CALL: Promote Health (Hp-2013) TOPIC: PROMOTE HEALTH (HP-2013) EC CONTRIBUTION: 837572 EUR KEYWORDS: Chronic Diseases, Collection of Best Practices, Elderly, Health system, Innovation initiatives PORTFOLIO: Ageing Page 2/9

SUMMARY General objectives The project aims to use multidimensional prognostic indices(mpi)that predict survival, based on a Comprehensive Geriatric Assessment (CGA), to improve the cost-effectiveness of health interventions in older individuals with multimorbidity and polypharmacy. The best setting-specific MPI-profile in which individual interventions are effective and reference models for allocate resources in healthcare will be identified to promote integrated care pathways of interventions. The general objective is to reduce unnecessary use of health care resources according to appropriate and tailored, integrated multi-professional, planned interventions to the older subjects. Strategic relevance and contribution to the public health programme The strategic relevance of the project is related to decreasing health-related costs while increasing cost-effectiveness of interventions, in order to assure an appropriate distribution of health resources according to the health needs of the older subjects. According to the Innovation Union Communication (IUC) launched by the Commission in 2010, the multidimensional, multidisciplinary and predictive strategies proposed by the project give relevant contribution to the EC programme in creating common and shared solutions that are closed to the specific needs of the aging population. Moreover the core activities of the project relate specifically to generating and disseminating health information and knowledge seeking to create evidence for policy makers and translating clinical practice into policy strategy that represents one of the 3 principal objectives of the second programme of Community action in the field of health (2008-13). Methods and means A web platform that facilitates the communication and monitoring of the activities among partners will be developed. In WP4 a retrospective analysis on the use of predictive rules in community-dwelling older subjects will be performed using clinical, functional and administrative data. In WP5 the best cost-effective profile of different therapeutic interventions in older individuals with different MPI-based mortality-risk profile will be identified. Specific activities of WP4 and WP5 will be addressed to identify the MPI-profiles that allow the development of the most cost-effective individual interventions to reduce adverse outcomes. In WP6 about 1000 subjects of both genders will be prospectively recruited in 10 clinical centers. Efficacy of interventions will be evaluated after 12 months of follow-up. A systematic process of dissemination and recommendations will be complete through the wide involvement Page 3/9

of partners, external experts and stakeholders in meetings and web diffusion. Expected outcomes period 1) Identifying the most effective interventions according to the multidimensional prognostic life-expectancy profile; 2) Improving multi-professional interaction and collaboration in performing shared multidimensional integrated care pathways of interventions; 3) Reducing hospitalization and institutionalization rates; 4) Reducing inappropriate and unnecessary drug use; 5) Reducing costs related to hospitalization or institutionalization. Page 4/9

COORDINATOR, LEADER CONTACT AND PARTNERS COORDINATOR (Azienda Unità Locale Socio Sanitaria N.16) Via Enrico degli Scrovegni,14 I-35131 Padova Italy Project leader contact Name: Pilotto Alberto Email: alberto.pilotto@sanita.padova.it Phone: 0039 049 821 4187 PARTNERS Univerzita Karlova v Praze Street: Ovocný trh 3/5 City: CZ-116 36 Prague 1 Country: Czech Republic Karolinska Institutet Street: Gävlegatan 16 City: SE-113 30 Stockholm Country: Sweden European Union Geriatric Medicine Society Street: Marjory Warren House 31 St John's Square City: UK-EC1M 4DN London Country: United Kingdom Page 5/9

Servicio Madrileño De Salud Street: Plaza Carlos Trias Bertran, 7 City: E-28020 Madrid Country: Spain Universitätsklinikum Köln AöR Street: Kerpener Straße 62 City: D-50937 Köln Country: Germany Fundación Para La Investigación Biomédica Del Hospital Universitario Ramón Y Cajal Street: Ctra. Colmenar Viejo. Km 9,100 City: E-28034 MADRID Country: Spain Erasmus Universitair Medisch Centrum Rotterdam Street: s-gravendijkwal City: NL-3015 CE Rotterdam Country: Netherlands Centre Hospitalier Universitaire de Poitiers Street: 2 rue de la Milétrie City: 86021 Poitiers Country: France Page 6/9

OUTPUTS D01 - Web-based Management Information Tool D02 - Interim Report (technical + financial) D03 - Final Report (technical + financial) D04 - Dissemination Strategy D05 - Develop and publish project leaflet Page 7/9

D06 - Internal and External Evaluation Reports D07 - Analysis report on the use of predictive rules in clinical decision making in communitydwelling older adults D08 - Report on the use of CGA-based MPI in improving cost-effectiveness of drug treatments in older individuals D09 - Report on the application of MPIs in different settings to improve the costeffectiveness of interventions. Page 8/9

Powered by TCPDF (www.tcpdf.org) D10 - Report with recommendations Page 9/9