7th INTERNATIONAL HYPOTHERMIA & TEMPERATURE MANAGEMENT SYMPOSIUM Sheraton on the Park Sydney, Australia. August 28-30, 2018

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August 28-30, 2018 Sheraton on the Park Sydney, Australia WWW.IHTMS.ORG 7th INTERNATIONAL HYPOTHERMIA & TEMPERATURE MANAGEMENT SYMPOSIUM Proudly supported by:

The 7th IHTMS is proudly supported by: IHTMS 2018-2

IHTMS 2018 - DAY ONE Tuesday 28th August 2018 Session One PLENARY ONE - Traumatic Brian Injury Hypothermia for Traumatic Intracranial Hypertension the future after EUROTHERM CLINICAL TRIALS ONE - Cardiac Arrest Hypothermia for Paediatric cardiac arrest Hypothermia for Adult cardiac arrest (24 vs. 48 hours) J-Pulse-Hypo: Registry, two temperature targets Rationale + update for the TTM2 study PANEL DISCUSSION ONE Peter Andrews United Kingdom Session Chair: Kjetil Sunde Seetha Shankaran United States of America Hans Kirkegaard Denmark Hiroshi Nonogi Japan Niklas Nielsen Sweden IHTMS 2018-3

IHTMS 2018 - DAY ONE Tuesday 28th August 2018 Session Two Recovering from Cardiac Arrest and Traumatic Brain Injury: is there a problem with the measurement of outcome? Nyrie Palmer Simpson, Mother of a patient who has recovered from Traumatic Brain Injury; Tobias Cronberg, Neurologist, Sweden; Gisela Lilja, Occupational Therapist, Sweden; Leanne Togher, Speech Pathologist, NSW; Jamie Cooper, Clinical Trialist, VIC; Seetha Shankaran, Paediatrician, USA; Kjetil Sunde, Oslo CPR Research Network, Norway; Emily Fitzgerald, Research Nurse, Sydney; Legal Representative End of Meeting - Day One POSTER VIEWING - NETWORKING DRINKS 1800-1900 Tuesday 28th August IHTMS 2018-4

IHTMS 2018 - DAY TWO Wednesday 29th August 2018 Session Three PLENARY TWO - Basic Science / Translation The Basic Science of Induced Cooling for Intracerebral Haemorrhage PLENARY THREE - Basic Science / Translation The Basic Science of Induced Cooling for Perinatal Birth Asphyxia PLENARY FOUR - Basic Science / Translation Induced Cooling Improves Clinical Outcomes After Perinatal Birth Asphyxia LECTURE SESSION ONE - Basic Science / Translation Systematic Review of Animal Models of Cardiac Arrest Systematic Review of Animal Models of Traumatic Brain Injury Panel Discussion: Translation of Basic Science to Clinical Trials - Pitfalls, promises and the patient Fred Colbourne United States of America Alistair Gunn New Zealand Seetha Shankaran United States of America Session Chair: Dalton Dietrich Hans Friberg Sweden Peter Andrews United Kingdom IHTMS 2018-5

IHTMS 2018 - DAY TWO Wednesday 29th August 2018 Session Four LECTURE SESSION TWO - The Hiyashi Prize Best Oral Presentation Basic Science Oral Presentations Clinical Oral Presentations IHTMS 2018 - DAY TWO Wednesday 29th August 2018 Session Five LECTURE SESSION THREE - The Practical application of TTM and novel approaches Induction, Maintenance and Re-warming Complications of Induced Cooling: Why age may matter Novel Modalities of Cooling: Pharmacology and hibernation Stephen Bernard Australia Markus Skirfvars Finland Fred Rincon IHTMS 2018-6

IHTMS 2018 - DAY TWO Wednesday 29th August 2018 Session Five continued LECTURE SESSION THREE - The Practical application of TTM and novel approaches...continued Novel biomarkers of neurological injury Brain Temperature: The real target for TTM Fever Control: What is it? + How to do it Pharmacology and Induced Cooling: A two way street Cooling the Conscious Patient Cooling Challenges: The nursing perspective Keeping Kids Cool Panel Discussion Hans Friberg Sweden Raimund Helbok Austria Manoj Saxena Australia Gretchen Brophy Kelly Harbour Australia John Beca New Zealand IHTMS 2018-7

IHTMS 2018 - DAY TWO Wednesday 29th August 2018 Session Six PLENARY FIVE The Importance of Brain Temperature on Concussion Dalton Dietrich United States of America End of Meeting - Day Two IHTMS 2018-8

IHTMS 2018 - DAY THREE Thursday 30th August 2018 Session Seven CLINICAL TRIALS TWO - New Applications Hypothermia for Spinal Cord Injury Hypothermia for Subdural Haemorrhage Hypothermia for Myocardial Ischaemia Hypothermia for the Organ Donor Panel Discussion Dalton Dietrich United States of America Hitoshi Kobata Japan IHTMS 2018-9

IHTMS 2018 - DAY THREE Thursday 30th August 2018 Session Seven continued LECTURE SESSION FOUR - Extra Corporeal Membrane Oxygenation + TTM The CHEER study Pre-hospital ECMO CPR: Establishing a service and evaluating outcomes The SAVE-J Study: Prospective National Registry: E-CPR Vs standard care Prognostication and E-CPR for Cardiac Arrest Stephen Bernard Australia M Conterato United States of America Tetsuya Sakomoto Japan Noritoshi Ito Japan Panel Discussion IHTMS 2018-10

IHTMS 2018 - DAY THREE Thursday 30th August 2018 Session Eight LECTURE SESSION FIVE - Multimodal monitoring for neurological injury: International approaches Beyond ICP and CPP: Brain metabolism under fever and TTM Automated EEG for monitoring after cardiac arrest. Induced Cooling and Brain Tissue Oxygenation The COMACARE Study: Effect of oxygen, carbon dioxide and MAP on brain oxygenation in CA patients undergoing TTM Cerebrovascular Autoregulation During Cooling Panel Discussion Session Chairs: Andrew Cheng & Andrew Udy Raimund Helbok Austria Tobias Cronberg Sweden Jonathon Rhodes United Kingdom Markus Skirfvars Finland Anders Aneman Australia IHTMS 2018-11

IHTMS 2018 - DAY THREE Thursday 30th August 2018 Session Eight continued CLINICAL TRIALS THREE - Infections in the critically ill Paracetamol for Infections Normothermia for Septic Shock Hypothermia for Septic Shock Hypothermia for Meningitis Panel Discussion Session Chair: Raimund Helbok Paul Young New Zealand Frederique Schortgen France Morten Bestle Denmark Frederique Schortgen France IHTMS 2018-12

IHTMS 2018 - DAY THREE Thursday 30th August 2018 Session NIne PANEL DISCUSSION TWO Session Chair: Simon Finfer & Celia Bradford From Evidence to Guidelines and the patient in front of me: Making sense of it all and where to from here? Dalton Dietrich, United States of America; Kjetil Sunde, Norway; Frederique Schortgen, France; David Gaeski, United States of America; Hiroshi Nonogi, Japan; John Beca, Paediatrics, New Zealand; Michael Parr, ARC, ILCOR: NSW, Australia; Peter Andrews, United Kingdom; Paul Young, New Zealand; Naomi Hammond, Australia; Gisela Lilja, Sweden; Niklas Nielsen, Sweden; Patient / Relative; Lay person representative End of Meeting 7th INTERNATIONAL HYPOTHERMIA & TEMPERATURE MANAGEMENT SYMPOSIUM DINNER 1800-2200 Thursday 29th August IHTMS 2018-13

The 7th IHTMS gratefully acknowledges the support of our meeting sponsors: PLATINUM SPONSORS We also thank BARD for their provision of a fixed unrestricted educational grant. GOLD SPONSORS IHTMS 2018-14