THE INTERVENTIONAL RADIOLOGIST CHRISTIAAN VAN DER LEIJ, MD. EBIR. INTERVENTIONAL RADIOLOGY MAASTRICHT UMC+

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THE INTERVENTIONAL RADIOLOGIST CHRISTIAAN, MD. EBIR. INTERVENTIONAL RADIOLOGY MAASTRICHT UMC+

DISCLOSURES None

78 Y/O FEMALE Painful RUQ Fever Lab: Raised Leukocytes/CRP

CHOLECYSTITIS 3-9% patients ER w Abdominal pain 95% associated with stones Diagnosis Fever, raised leukocytes/crp, positive Murphy US (sens 81%, spec 83%) Stones, distension, wall thickening w hyperemia, impacted stone, PAIN CT (sens 92%, spec 99%) Stones, distension, wall thickening w hyperenhancement, pericholecystic fluid/stranding, liver parenchyma enhancement KIEWIET JJS, LEEUWENBURGH MMN, BIPAT S, BOSSUYT PMM, STOKER J, BOERMEESTER MA. A SYSTEMATIC REVIEW AND META- ANALYSIS OF DIAGNOSTIC PERFORMANCE OF IMAGING IN AC BENNETT GL, RUSINEK H, LISI V, ISRAEL GM, KRINSKY GA, SLYWOTZKY CM ET AL. CT FINDINGS IN ACUTE GANGRENOUS CHOLECYSTITIS. J ROENTGENOL 2002;178(20:275-81.

US CT

TREATMENT Cholecystectomy acute <7 days Conservative Drainage If conservative fails high risk patients (ASA IV) as diagnostic

PERCUTANEOUS CHOLECYSTOSTOMY Succes: 85% Transhepatic vs direct(transperitoneal) TH: Faster tract formation, better fixation, no colon-damage VS TP: less chance pneumothorax, bleeding, fistula Morbidity/mortality due to underlying disease Drain dislocation: up to 25% Peritonitis 6% HATZIDIKAS AA, KARAMPEKIOS S, PRASSEPOULOS P, XYNOS E, RAISSAKI M, VASILAKIS SI ET AL. MATURATION OF THE TRACT AFTER PERCUTANEOUS CHOLECYSTECTOMY WITH REGARD TO THE ACCE WINDBLADH A, GULLSTRAND P, SVANVIK J, SANDSTRÖM P. SYSTEMATIC REVIEW OF CHOLECYSTOSTOMY AS A TREATMENT OPTION IN ACUTE CHOLECYSTITIS. HPB (OXFORD) 2009;11(3):183-93.

HOW I DO IT Always ultrasound guided! w radiographic support (Interventional suite) (Almost) always direct Local anaesthetic Lidocain 1% 10 ml Locked pigtail 10 fr Suture

AFTER DRAINAGE Drain removal: 2 (TH) or 3(TP) weeks w cholecystography determine patency cystic duct

82 Y/O FEMALE PATIENT Cholangitis Fever, raised bilirubin,leukocytes, CRP US: bile duct dilatation Percutaneous Transhepatic Biliary Drainage (PTBD)

CHOLANGITIS Systemic inflammation, cholestasis, dilatation Treatment: decompression + AB Decompression ERCP (+papillotomy)/ptc/surgical ERCP vs surgery: morb 34% vs 66%, mort 10 vs 32% ERCP vs PTBD: no clear data LAI EC, MOK FP, TAN ES, LO CM, FAN ST, YOU KT ET AL. ENDOSCOPIC BILIARY DRAINAGE FOR SEVERE ACUTE CHOLANGITIS. N ENGL J MED 1992;326(24):1582-6.

CHOLEDOCHOLITHIASIS Prevalence: 3,4-16% patients w cholecystectomy indication Usually in combination with gallbladder stones Predictive factors Cholangitis, icterus, stones on US, dilatation, hyperbilirubinemia Diagnosis (Clinical) US (sens 38%, spec 100%) EUS (sens 94, spec 95%) MRCP (sens 92%, spec 94%) RICKES S, TREIBER G, MONKEMULLER K, PEITZ U, CSEPREGI A, KAHL S ET AL. IMPACT OF THE OPERATOR S EXPERIENCE ON VALUE OF HIGH RESOLUTION TRANSABDOMINAL ULTRASOUND IN THE DIAGNOSIS TSE F, LIU L, BARKUN A, ARMSTRONG D, MOAYYEDI P. EUS: A META-ANALYSIS OF TEST PERFORMANCE IN SUSPECTED CHOLEDOCHOLITHIASIS. GASTROINTEST ENDOSC 2008;67(2):235-44. GARROW D, MILLER S, SINHA D, CONWAY J, HOFFMAN BJ, HAWES RH ET AL. ENDOSCOPIC ULTRASOUND: A META-ANALYSIS OF TEST PERFORMANCE IN SUSPECTED BILIARY OBSTRUCTION. CLIN GASTROENT ABBOUD PA, MALET PF, BERLIN JA, STAROSCIK R, CABANA MD, CLARKE JR ET AL. PREDICTORS OF COMMON BILE DUCT STONES PRIOR TO CHOLECYSTECTOMY: A META-ANALYSIS. GASTROINTEST ENDOSC 1

CHOLEDOCHOLITHIASIS TREATMENT ERCP + papillotomy + stone extraction +/- Cholecystectomy Percutaneous stone extraction if ERCP not possible Altered anatomy (Bilioenteric anastomosis, Gastric bypass etc..) Not succesful ERCP +/- Rendez-Vous

PERCUTANEOUS CBD STONE EXTRACTION Preferentially under deep sedation, local anaesthetics PTBD left/right side Left side less catheter dislocation(?) Left side more comfortable Ultrasound and/or fluoroscopy guided Stone extraction: balloonpapillotomy stone extraction w balloon dormia basket/snares Flushing

PERCUTANEOUS TRANSHEPATIC STONE EXTRACTION Drainage tube external/internal drainage at least 10 days Next day cholangiography residual stones multiple sessions if needed Rendez-vous if needed/possible

RESULTS/OUTCOME/COMPLICATIONS

MALE 37 Y/O Choroid melanoma Imaging for dissemination: Left sided dilatation bile ducts No mass visible

1ST 2ND 3TH 4TH

1ST 2ND 3TH 4TH

1ST 2ND 3TH 4TH

1ST 2ND 3TH 4TH

1ST 2ND 3TH 4TH

INTRAHEPATIC STONES Perform PTBD where needed! Same techniques as CBD stones Dilatation up to 6/7 mm max!

MALE 44 Y/O Post cholecystectomy abdominal fluid collection

MRCP

MRCP

BILE DUCT INJURY Most iatrogenic incidence 0,04-1,5% cholecystectomy recognised during surgery in only 42% Types (Amsterdam Classification) A: Leaks of cystic duct or aberrant/peripheral radicles B: Major bile duct leaks w or w/o stricture C: stricture, no leakage D: Complete transection Bismuth, Strasberg, McMahon, Stewart-Way, Hannover, Mattox BERGMAN JJ1, VAN DEN BRINK GR, RAUWS EA, DE WIT L, OBERTOP H, HUIBREGTSE K, TYTGAT GN, GOUMA DJ TREATMENT OF BILE DUCT LESIONS AFTER LAPAROSCOPIC CHOLECYSTECTOMY. GUT. 1996 JAN;38(1)

STEWART-WAY HANNOVER STRASBERG BISMUTH

BILE DUCT INJURY - TREATMENT Peroperative: Direct anastomosis over T-drain Hepaticojejunostomy A/B/C: ERCP + stentplacement (type A: nasobiliary drain) successa/b/c: 94/80-90/50% D: reconstructive surgery A-D: Percutanous approach

AMSTERDAM TYPE D LESION (STRASBERG C) 1st step: peritoneal drain! as close to the point of leakage as possible containment PTBD Non dilated ducts Deep sedation which segment MRCP! External drainage - internal drainage (weeksmonths) Use peritoneal drain as marker

8 WEEKS LATER

TYPE A LESION

2 WEEKS LATER

TO CONCLUDE Gallbladder drainage after failure of conservative treatment, as diagnostic, in high risk patients Transhepatic/Transperitoneal PTBD in choledocholithiasis if ERCP is not possible/succesful (eg. altered anatomy) PTBD Preferentially under deep sedation, left side (less dislocation/more comfortable) Leave drain at least 10 days

TO CONCLUDE Percutaneous CBD stone removal is effective and safe one/multiple sessions Peripheral stones PTBC is effective in bile duct lesions Start with peritoneal drain (near hilum) Longstanding drainage external - internal

CHRISTIAAN.VANDER.LEIJ@MUMC.NL