Positive and Negative Symptoms of Psychosis The Care Transitions Network

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Positive and Negative Symptoms of Psychosis The Care Transitions Network National Council for Behavioral Health Montefiore Medical Center Northwell Health New York State Office of Mental Health Netsmart Technologies

Objectives By the end of this webinar, participants will be able to: Identify negative symptoms of psychosis Elicit positive symptoms of psychosis Identify various types of hallucinations Identify different delusional themes Evaluate severity of hallucinations and delusions

Symptoms of Psychosis Disorganized Symptoms Grossly Disorganized or Catatonic Behavior 4 5 Negative Symptoms Disorganized Speech 3 Positive Symptoms Delusions 2 Hallucinations 1

Negative Symptoms Inability to initiate and persist in goal-directed activities or diminished emotional expressiveness

Negative Symptoms These are the lack of a normal function: Lack of affect Impoverished speech Lack of motivation Decreased ability to enjoy things Social withdrawal

Month Day, Year 6

Negative Symptoms Can Also Present As Thought Disorder Poverty of Speech Lack of additional, unprompted spontaneous speech Insufficient speech One word answers It may represent a symptom of catatonia (mutism) This is distinguished from another form of Thought Disorder, Poverty of Content, in which the amount of speech is sufficient but little information is conveyed

Negative Symptoms Negative symptoms contribute to social and functional decline When present, they often remain as residual symptoms even when positive symptoms resolve They are often present for weeks or months prior to the initial onset of positive symptoms; when this happens they are called "Prodromal" symptoms Prodromal symptoms may also include attenuated positive symptoms When new onset negative symptoms occur without prior history of a "first break" of psychosis, it warrants screening for positive symptoms

Positive Symptoms

Hallucinations Perceptual experiences that occur without an external stimulus

Hallucination A perception-like experience with the clarity and impact of a true perception, but without the external stimulation of the relevant sensory organ e.g., hearing voices

Hallucinations They may occur in any sensory modality, but auditory hallucinations are the most common in schizophrenia and related disorders Auditory hallucinations can be experienced as voices whether familiar or unfamiliar and distinct from the individual s own thoughts They can also manifest as more acute hearing, or other noises such as buzzing, static, or beeping

Hallucinations Visual hallucinations are more common in medically-induced disorders such hallucinations associated with seizures or alcohol withdrawal Tactile hallucinations of bugs on the skin are often associated with alcohol withdrawal Hallucinations occurring while falling asleep (hypnagogic) or waking up (hypnopompic) are normal experiences

Questions to Elicit Hallucinations Do you ever hear things that other people can t, such as noises, or the voices of people whispering or talking? Do you ever have visions or see things that other people can t see? What about strange sensations on your skin, like feeling like something is creeping or crawling on or under your skin? How about the feeling of being touched or stroked? What about having unusual sensations inside a part of your body, like a feeling of electricity?

Questions to Elicit Hallucinations How about eating or drinking something that you thought tasted bad or strange even though everyone else who tasted it thought it was fine? What about smelling unpleasant things that other people couldn t smell, like decaying food or dead bodies?

Interview Techniques Ask if the hallucinatory experience occurred when waking up or falling asleep It is often helpful to ask specific questions and follow positive responses with open ended requests for more information, such as: Tell me about that Questioning about hallucinations can often be a segue into questioning about delusions, as hallucinations are often accompanied by a delusional interpretation

Evaluating Severity of Hallucinations For hallucinations, severity is based on: Frequency Level of Distress Impact on Behavior

Interview Techniques Follow up questions for severity, safety assessment, functional impairment, and distress are helpful: How often does this occur? How much does it bother you? Do the voices tell you to do things? Harmful things? Do you ever do what the voices say? Do you change your behavior in response to these experiences? Does this distract you concentration or your ability to focus on work or school? Do you talk to the voices? Do the voices comment of your actions? Do the voices have conversations with each other?

Month Day, Year 20

Delusions Fixed beliefs that are not amenable to change in light of conflicting evidence

Delusion A false belief based on incorrect inference about external reality The belief is firmly held despite what almost everyone else believes The belief is firmly held despite what constitutes incontrovertible and obvious proof or evidence to the contrary The belief is not one ordinarily accepted by other members of the person s culture or subculture

Delusions Delusions content may include a variety of themes: Persecutory Delusions Referential Delusions Grandiose Delusions Erotomanic Delusions Nihilistic Delusions Somatic Delusions

Delusions of Control Body control Thought insertion Thought withdrawal Thought broadcasting Mindreading

Delusional Misidentification Syndromes Capgras delusion Fregoli delusion Cotard delusion

Evaluating Severity of Delusions For delusions, severity is based on: Level of Conviction Impact on Behavior

Month Day, Year 28

Month Day, Year 30

Next Steps 1.Review the companion materials for helpful questions to elicit the presence of delusions and hallucinations 2.Schedule a training on diagnosing psychotic disorders for your clinicians 3.Stay tuned for the next webinar in which we review disorganized symptoms This will include disorganized behavior and catatonia It will also include disorganized language or thought disorder which can be represented as both a positive symptom, a negative symptom, or a sign of catatonia

References American Psychiatric Association. (2013). Diagnostic and statistical manual of mental disorders (5th ed.) First MB, Williams JBW, Karg RS, Spitzer RL: Structured Clinical Interview for DSM-5 Research Version (SCID-5 for DSM-5, Research Version; SCID-5-RV). Arlington, VA, American Psychiatric Association, 2015. Christodoulou GN. The Delusional Misidentification Syndromes. (1986). S. Karger AG, P.O. Box, CH-4009 Basel (Switzerland).

Thank you! www.caretransitionsnetwork.org CareTransitions@TheNationalCouncil.org The project described was supported by Funding Opportunity Number CMS-1L1-15-003 from the U.S. Department of Health & Human Services, Centers for Medicare & Medicaid Services. Disclaimer: The contents provided are solely the responsibility of the authors and do not necessarily represent the official views of HHS or any of its agencies.