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anesthesia & mass casualty events marc p steurer, md, desa president, trauma anesthesiology society (www.tashq.org) director, trauma anesthesiology UCSF/ SFGH associate professor UCSF

faculty disclosure Marc P Steurer, MD, DESA I am experienced in this area I have no conflicts of interest to disclose

why are we talking about this?

content SF current risk assessment best practice for mass casualty events for anesthesia

San Francisco General Hospital & Trauma Center Updated Hazard Vulnerability & Impact Analysis (HVA) annual analysis TJC mandate involves probability of occurrence risk preparedness status

TJC define point-in-time and longitudinal surge capacity aid agreements with others 48-72h stand alone capability (personnel and materials) direct caregivers; training & equipment maintain ability to provide routine care incident command program testing, <1/yr oversight of preparedness system

for the year 2015 (risk = probability * severity) major earthquake (78% risk) electrical power failure/ info system failure (61% risk) epidemic/ disease outbreak (50% risk) multi casualty incident (44% risk) active shooter (41% risk) water failure, internal flood, drought (39% risk)

content SF current risk assessment best practice for mass casualty events for anesthesia

role of anesthesia/ologist likelihood complexity provide care organize care triage organize systems

what do you need to be successful in those roles? organizational setup in place good clinical care

what do you need to be successful in those roles? trauma anesthesia/ resources checklists trauma anesthesia massive bleeding/transfusion mass casualty organization/ triage

www.tashq.org

what do you need? trauma anesthesia/ resources checklists trauma anesthesia massive bleeding/transfusion mass casualty organization/ triage

general trauma anesthesia checklist

SFGH trauma anesthesia checklist Stop%the%bleeding% Call%for%help% Control%airway%&%FiO2%100%% Activate%MTP% Consider%6x%O+%PRBC%in%main%OR% Large%bore%peripheral%(>16G)%or%central%access%(cordis/%MAC)% Belmont%rapid%infuser% Damage%control%resuscitation% o Permissive%hypotension%! SBP%<100mmHg%! MAP%50S60%! Individual%decision%if:%severe%TBI,%significant% carotid%stenosis/%cad% o Judicious%use%of%crystalloids/%colloids% o Early%use%of%blood%products%! Initial%transfusion%empiric%1:1:1%! Consider%1g%of%Calcium%for%every%3%blood%products%! Avoid%vasoconstrictors% Arterial%line%placement%&%point%of%care%testing%(ABG,%ROTEM)% Tailored%resuscitation% o Use%ROTEM%to%guide%coagulopathy%resuscitation% o Use%ABG%to%guide%hematocrit% o Use%clinical%signs%&%serial%Lactate/%BE%to%guide%fluid% administration% Prevent%hypothermia% o Esophageal%temperature%probe% o Warmed%fluids%only% o Bair%hugger%upper%body%&%lower%body% o Elevated%room%temperature% Consider%cell%saver% Repeat%point%of%care%testing%(ABG%&%ROTEM)%every%30%minutes% After%surgical%hemostasis% o Rapid%intravascular%filling% o Step%wise%deepening%of%anesthesia%! Repeated%Fentanyl%boluses%! Incremental%vapor%concentration% o Possible%use%of%vasoactive%infusions% o Goal:%normalization%of%Lactate%and%Base%Deficit% Consider%Foley%catheter% Constant%communication%with%all%team%members% Deactivate%MTP%when%appropriate% %

SFGH trauma anesthesia checklist Stop the bleeding Call for help Control airway & FiO2 100% Activate MTP Consider 6x O+ PRBC in main OR Large bore peripheral (>16G) or central access (cordis/ MAC) Belmont rapid infuser

SFGH trauma anesthesia checklist Damage control resuscitation Permissive hypotension SBP <100mmHg MAP 50-60 Individual decision if: severe TBI, significant carotid stenosis/ CAD Judicious use of crystalloids/ colloids Early use of blood products Initial transfusion empiric 1:1:1 Consider 1g of Calcium for every 3 blood products Avoid vasoconstrictors

SFGH trauma anesthesia checklist Arterial line placement & point of care testing (ABG, ROTEM) Tailored resuscitation Use ROTEM to guide coagulopathy resuscitation Use ABG to guide hematocrit Use clinical signs & serial Lactate/ BE to guide fluid administration Prevent hypothermia Esophageal temperature probe Warmed fluids only Bair hugger upper body & lower body Elevated room temperature

SFGH trauma anesthesia checklist Consider cell saver Repeat point of care testing (ABG & ROTEM) every 30 minutes After surgical hemostasis Rapid intravascular filling Step wise deepening of anesthesia Repeated Fentanyl boluses Incremental vapor concentration Possible use of vasoactive infusions Goal: normalization of Lactate and Base Deficit Consider Foley catheter Constant communication with all team members Deactivate MTP when appropriate

M"Steurer" " March"2014"! SFGH anesthesia coagulation algorithm! Preoperative History Bleeding HX Medication (Aspirin, GIIb/IIIa inhibitors, Coumadin, Heparin, LMWH etc.) Preoperative Coagulation Parameters INR, PT, PTT, Fibrinogen, plts IF Clopidogrel within 10days tranexamic acid/ amicar BLOOD LOSS >30-50% and ACTIVE, DIFFUSE BLEEDING ROTEM (extem, intem, fibtem, aptem) heptem if Heparin given (i.e. vascular case) ABG ROTEM (extem, intem, fibtem, aptem) as early as possible major vascular/ orthopedic surgery major tumor surgery trauma (TBI, multisystem trauma, chest trauma, hemorrhagic shock) obstetric catastrophe Always correct Temperature > 36 C (bair hugger, warm infusion, room temperature, HME) Calcium, ionized > 1.10 mmol/l Acidosis, ph > 7.20 Anemia, Hb > 7-9 g/l Hypertension, MAP 55-65 mmhg (TBI MAP 80-90 mmhg) Hypoxia, PaO2 >100, but < 200 mmhg Consider PRBC:FFP in a 2:1 ratio fibtem, A10 < 8 mm Cryoprecipitate 1-2 units (each unit is a 5pack) extem, A10 < 30 mm ( & fibtem A10 > 10mm) Platelet concentrates (each unit is a 6pack) extem/ intem > 15 % lysis 1 st choice: Tranexamic acid 1g alternative: Aminocaproic acid 4-5g intem, CT > 240 sec & CThep/CTin < 0.8 Protamine sulfate 1:1 Blood loss > 60% and ACTIVE, DIFFUSE BLEEDING ROTEM (extem, intem, fibtem, aptem) heptem if Heparin given Same goals as under 30-50% blood loss (i.e. vascular case) abga Consider PRBC:FFP in a 1:1 ratio INR, PT, PTT, Fibrinogen, plts Plts > 75,000/mcl BLOOD LOSS > 100-150% ROTEM (extem, intem, fibtem, aptem) heptem if Heparin given (i.e. vascular case) abga INR, PT, PTT, Fibrinogen, plts fibtem < 12 mm extem, A10 < 40 mm & fibtem A10 > 10mm extem/ intem > 15 % lysis extem CT > 90 sec2 ONGOING MASSIVE DIFFUSE HEMORRHAGE With corrected Acidosis Hypothermia Hypocalcemia Hct > 21 24% Fibrinogen level Plts > 100,000/mcl! Same goals as under 30-50% blood loss PRBC:FFP:plts in a 1:1:1 ratio (give 6pack of plts early) Plts > 100,000/mcl Cryoprecipitate 2 units (each unit is a 5pack) Platelet concentrates (each unit is a 6pack) 1 st choice: Tranexamic acid 1g alternative: Aminocaproic acid 4-5g Consider PCC (Kcentra ) 20-40 IU/kg Consider rfviia (NovoSeven) 40 90 mcg/kg bolus Repeat: half of initial dose after 2-4hours Consider 2) DDAVP

mass casualty checklist Consult Disaster Manual. Assign someone to activate the call-in disaster list. Assess the number of available ORs that you can staff immediately and over next several hours. Contact running ORs and alert them to finish as soon as safely possible and prepare for trauma. Assign free staff to set up for trauma/emergency cases. Anesthesia floor manager should co-locate with the OR nursing manager to ease communication and coordination. (Anesthesia floor manager should become OR Medical Director until relieved.) Hold up elective cases. Coordinate with anesthesia techs to ensure adequate supplies of fluids, drugs, disposables. Call PACU to accelerate transfer of post op patients to floors/icus. Send a senior anesthesiologist to the ED to act as a liaison (your eyes and ears). Consider assembling additional "stat" teams. If HAZMAT or WMD event, review special personal protective procedures such as DECON and isolation techniques. Consider if part of the OR or hallways should be considered "hot" or should have ventilation altered. Jay McIsaac, MD

SALT triage Lerner et al, USE OF SALT TRIAGE IN A SIMULATED MASS-CASUALTY INCIDENT, PREHOSPITAL EMERGENCY CARE. 2010;14:21 25

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