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Page 1 of 23 d Rituximab (Rituxan ) Palmetto GBA Jump to Section... Please note: This is a Future LCD. Please note: This is a Draft policy. Proposed/Draft LCDs are works in progress that are available on the Medicare Coverage Database site for public review. Proposed/Draft LCDs are not necessarily a reflection of the current policies or practices of the contractor. Contractor Name Contract Number Contract Type Palmetto GBA 11201 MAC - Part A Associated Contract Numbers (MAC - Part A - 11501) Palmetto GBA, (MAC - Part A - 11301) Palmetto GBA, (MAC - Part A - 11401) Palmetto GBA Proposed/Draft LCD Information

Page 2 of 23 Source LCD ID N/A Proposed LCD ID Original ICD-9 LCD ID Proposed LCD Version Number Proposed LCD Title AMA CPT / ADA CDT Copyright Statement CMS National Coverage Policy DL35185 Not applicable 2 Rituximab (Rituxan ) CPT only copyright 2002-2013 American Medical Association. All rights reserved. CPT is a registered trademark of the American Medical Association. Applicable FARS/DFARS Apply to Government Use. Fee schedules, relative value units, conversion factors and/or related components are not assigned by the AMA, are not part of CPT, and the AMA is not recommending their use. The AMA does not directly or indirectly practice medicine or dispense medical services. The AMA assumes no liability for data contained or not contained herein. The Code on Dental Procedures and Nomenclature (Code) is published in Current Dental Terminology (CDT). Copyright (c) American Dental Association. All rights reserved. CDT and CDT-2010 are trademarks of the American Dental Association. Title XVIII of the Social Security Act(SSA) 1862(a)(1)(A), Allows coverage and payment for only those services that are considered to be medically reasonable and necessary. Title XVIII of the Social Security Act (SSA) 1861(t)(2)(B), Drugs and Biologicals Title XVIII of the Social Security Act (SSA) 1833(e), prohibits Medicare payment for any claim lacking the necessary documentation to process the claim. Title XVIII of the Social Security Act (SSA) 1862(a)(1)(D), Investigational or Experimental. CMS Internet-Only Manual, Pub. 100-02, Medicare Benefit Policy Manual, Chapter 15, Section 50; 50.4.1, 50.4.2, 50.4.3, 50.4.5; Drugs and Biologicals. CMS Internet-Only Manual, Pub. 100-04, Medicare Claims Processing Manual, Chapter 17, Section 40; Discarded Drugs and Biologicals Jurisdiction SC Coverage Guidance Coverage Indications, Limitations and/or Medical Necessity Rituxan(rituximab) is a genetically engineered chimeric murine/human monoclonal IgG1 kappa antibody directed against the CD20 antigen. Rituximab binds specifically to the antigen CD20 (human B-lymphocyte-restricted differentiation antigen, Bp35), a hydrophobic transmembrane protein with a molecular weight of approximately 35 kd located on pre-b and mature B lymphocytes. The antigen is expressed on > 90% of B-cell Non-Hodgkin s Lymphomas (NHL), but the antigen is not found on hematopoietic stem cells, pro-b-cells, normal plasma cells or other

Page 3 of 23 normal tissues. B cells are believed to play a role in the pathogenesis of rheumatoid arthritis (RA) and associated chronic synovitis. In Non-Hodgkin s Lymphoma (NHL) patients, administration of Rituxan resulted in depletion of circulating and tissue-based B cells. In Wegeners Granulomatosis with Polyangiitis and Microscopic Polyangiitis patients, peripheral blood CD19 B-cells depleted to less than 10 cells/μl following the first two infusions of Rituxan, and remained at that level in most (84%) patients through Month 6. By Month 12, the majority of patients (81%) showed signs of B-cell return with counts >10 cells/μl Rituximab is indicated for the following FDA approved uses: 1. Non Hodgkin s Lymphoma (NHL Rituxan(rituximab)is indicated for the treatment of patients with: Relapsed or refractory, low-grade or follicular, CD20-positive, B-cell NHL as a single agent. Previously untreated follicular, CD20-positive, B-cell NHL in combination with first line chemotherapy and, in patients achieving a complete or partial response to Rituxan in combination with chemotherapy, as single-agent maintenance therapy. Non-progressing (including stable disease), low-grade, CD20-positive, B-cell NHL as a single agent after first-line CVP chemotherapy. Previously untreated diffuse large B-cell, CD20-positive NHL in combination with CHOP (Cyclophosphamide, Doxorubicin, Vincristine, and Prednisone)or other anthracycline-based chemotherapy regimens. 2.Chronic Lymphocytic Leukemia (CLL) Rituxan (rituximab) is indicated, in combination with fludarabine and cyclophosphamide (FC), for the treatment of patients with previously untreated and previously treated CD20-positive CLL. 3. Rheumatoid Arthritis (RA) Rituxan (rituximab) in combination with methotrexate is indicated for the treatment of adult patients with moderately- to severely- active rheumatoid arthritis who have had an inadequate response to one or more TNF antagonist therapies. 4. Granulomatosis with Polyangiitis (GPA) (Wegener s Granulomatosis) and Microscopic Polyangiitis(MPA) Rituxan(rituximab), in combination with glucocorticoids, is indicated for the treatment of adult patients with Granulomatosis with Polyangiitis (GPA) (Wegener s Granulomatosis) and Microscopic Polyangiitis (MPA). 5. Accepted Off-label Uses Approved by Palmetto GBA Second-line or salvage therapy with or without radiation therapy (RT) prior to autologous stem cell rescue for progressive disease or for relapsed disease in patients initially treated with chemotherapy with or without RT in combination with bendamustine. Low grade or follicular CD20-positive, B-cell non-hodgkin s lymphomas (re-induction treatment appropriate for responders and patients with stable disease). Intermediate and high grade NHL when used as a single agent, in combination with a CHOP (Cyclophosphamide, Doxorubicin, Vincristine, and Prednisone) chemotherapy regimen, or in combination with other agents active in the disease. Immune or idiopathic thrombocytopenia purpura Evans syndrome Waldenstrom s Macroglobulinemia

Page 4 of 23 For the treatment of refractory thrombotic thrombocytopenic purpura (TTP) for patients who do not respond to plasmapheresis. Autoimmune hemolytic anemia - Rituximab is covered for those patients with autoimmune hemolytic anemia condition that is refractory to conventional treatment (e.g., corticosteroid treatment and splenectomy). Multifocal Motor Neuropathy (NMN) second line (as a second line therapy) Multiple Sclerosis, relapsing, remitting (RRMS) (as a third line therapy) Neuromyelitis Optica Polymyositis (as a second or third line therapy) Myasthenia Gravis Anti-MAG Polyneuropathy Other off label uses will not be covered at this time. Proposed/Draft Process Information Associated Information Documentation Requirements Medical records must substantiate the medical need for the use of these chemotherapy drugs by clearly indicating the diagnoses for which these drugs are being used. We would expect the disease, the type of malignancy if cancer is the diagnosis; the staging, if applicable; all prior therapy and the patient s response to that therapy. For lymphoma patients receiving Rituximab, an explanation of lymphoma type and previous treatment(s) should be maintained in the medical record. All the documentation suggested here is usually found in the history and physical or the office/progress notes and must be available to Palmetto GBA on request. If the provider is other than the ordering/referring physician, that provider must maintain copies of the ordering/referring physician s order for the chemotherapy drug. The ordering/referring physician must state the clinical indication/medical need for using the chemotherapy drug in the order. For the off-label indication of autoimmune hemolytic anemia, in addition to the diagnosis and prior therapy requirements, other documentation required in the medical record: hemoglobin and hematocrit, reticulocyte count, bilirubin, liver function tests, and patient's subjective complaints. Sources of Information and Basis for Decision 1.Rituxan(rituximab) [package insert] Genentech, Inc. 1 DNA Way, South San Francisco, CA 2.Colombat P, Salles G, Brousse N, et al. Rituximab (anti-cd20 monoclonal antibody) as a single first-line therapy for patients with follicular lymphoma with a low tumor burden: clinical and molecular evaluation. Journal American Society of Hematology. 2001;97(1):101-106. This article supports off-labeled indications (1st line therapy) for this drug. 3.Edwards JC, Szczepanski L, Szechinski J, et al. Efficacy of B-Cell Targeted Therapy with Rituximab in Patients with Rheumatoid Arthritis. N Engl J Med. Jun 2004;350(25):2572-81. 4.Heidel, F., Lipka, D., et al. Addition of Rituximab to standard therapy improves response rate and progression-free survival in relapsed or refractory thrombotic thrombocytopenia purpura and autoimmune hemolytic anemia. Thrombosis and Hemostasis. 2007;97(2)228-233. 5.National Comprehensive Cancer Network (NCCN) Drugs & Biologics Compendium (2012).

Page 5 of 23 Rituximab. 6.National Comprehensive Cancer Network. Hodgkin Lymphoma: Principles of systemic therapy. Clinical Practice Guidelines in Oncology. 2012;1. HODG-B, 2. 7.Pamuk G, Turgut B, et al. The successful treatment of refractory autoimmune hemolytic anemia with rituximab in a patient with chronic lymphocytic leukemia.american Journal of Hematology. 2006;81:631-33. 8.Vose, J, Link, B, Grossbard M, Czuczman M, Grillo-Lopez A, Gilman P, et al. Phase II study of Rituximab in combination with CHOP chemotherapy in patients with previously untreated, aggressive non-hodgkin s lymphoma. Journal of Clinical Oncology. 2001;19(2):389-97. 9.LCD L29271, Rituxan, First Coast Service Options, Inc. 6/08/12 Open Meetings Meeting Date Meeting Information State 04/28/2014 via telephone conference North Carolina, South Carolina, Virginia, West Virginia Comment Period Start Date Comment Period End Date Released to Final LCD Date Reason for Proposed LCD Proposed LCD Contact 04/28/2014 06/12/2014 Not yet released. Provider Education/Guidance Margaret Cox Palmetto GBA PO Box 100238 Columbia, SC 29202 Margaret.Anne.Cox@Palmettogba.com Coding Information Bill Type Codes 011x Hospital Inpatient (Including Medicare Part A) 012x 013x 018x Hospital Inpatient (Medicare Part B only) Hospital Outpatient Hospital - Swing Beds

Page 6 of 23 021x Skilled Nursing - Inpatient (Including Medicare Part A) 022x 085x Skilled Nursing - Inpatient (Medicare Part B only) Critical Access Hospital Revenue Codes 0250 Pharmacy - General Classification 0636 Pharmacy - Drugs Requiring Detailed Coding CPT/HCPCS Codes Group 1: Paragraph Group 1: Codes J9310 INJECTION, RITUXIMAB, 100 MG Does the CPT 30% Coding Rule Apply? ICD-10 Codes that Support Medical Necessity Note: Performance is optimized by using code ranges. No Group 1: Paragraph Group 1: Codes C81.00 Nodular lymphocyte predominant Hodgkin lymphoma, unspecified site C81.01 Nodular lymphocyte predominant Hodgkin lymphoma, lymph nodes of head, face, and neck C81.02 Nodular lymphocyte predominant Hodgkin lymphoma, intrathoracic lymph nodes C81.03 Nodular lymphocyte predominant Hodgkin lymphoma, intra-abdominal lymph nodes C81.04 Nodular lymphocyte predominant Hodgkin lymphoma, lymph nodes of axilla and upper limb C81.05 Nodular lymphocyte predominant Hodgkin lymphoma, lymph nodes of inguinal region and lower limb C81.06 Nodular lymphocyte predominant Hodgkin lymphoma, intrapelvic lymph nodes C81.07 Nodular lymphocyte predominant Hodgkin lymphoma, spleen C81.08 Nodular lymphocyte predominant Hodgkin lymphoma, lymph nodes of multiple sites C81.09 Nodular lymphocyte predominant Hodgkin lymphoma, extranodal and solid organ sites C81.10 Nodular sclerosis classical Hodgkin lymphoma, unspecified site C81.11 Nodular sclerosis classical Hodgkin lymphoma, lymph nodes of head, face, and neck C81.12 Nodular sclerosis classical Hodgkin lymphoma, intrathoracic lymph nodes C81.13 Nodular sclerosis classical Hodgkin lymphoma, intra-abdominal lymph nodes C81.14 Nodular sclerosis classical Hodgkin lymphoma, lymph nodes of axilla and upper limb C81.15 Nodular sclerosis classical Hodgkin lymphoma, lymph nodes of inguinal region and lower limb

Page 7 of 23 C81.16 Nodular sclerosis classical Hodgkin lymphoma, intrapelvic lymph nodes C81.17 Nodular sclerosis classical Hodgkin lymphoma, spleen C81.18 Nodular sclerosis classical Hodgkin lymphoma, lymph nodes of multiple sites C81.19 Nodular sclerosis classical Hodgkin lymphoma, extranodal and solid organ sites C81.20 Mixed cellularity classical Hodgkin lymphoma, unspecified site C81.21 Mixed cellularity classical Hodgkin lymphoma, lymph nodes of head, face, and neck C81.22 Mixed cellularity classical Hodgkin lymphoma, intrathoracic lymph nodes C81.23 Mixed cellularity classical Hodgkin lymphoma, intra-abdominal lymph nodes C81.24 Mixed cellularity classical Hodgkin lymphoma, lymph nodes of axilla and upper limb C81.25 Mixed cellularity classical Hodgkin lymphoma, lymph nodes of inguinal region and lower limb C81.26 Mixed cellularity classical Hodgkin lymphoma, intrapelvic lymph nodes C81.27 Mixed cellularity classical Hodgkin lymphoma, spleen C81.28 Mixed cellularity classical Hodgkin lymphoma, lymph nodes of multiple sites C81.29 Mixed cellularity classical Hodgkin lymphoma, extranodal and solid organ sites C81.30 Lymphocyte depleted classical Hodgkin lymphoma, unspecified site C81.31 Lymphocyte depleted classical Hodgkin lymphoma, lymph nodes of head, face, and neck C81.32 Lymphocyte depleted classical Hodgkin lymphoma, intrathoracic lymph nodes C81.33 Lymphocyte depleted classical Hodgkin lymphoma, intra-abdominal lymph nodes C81.34 Lymphocyte depleted classical Hodgkin lymphoma, lymph nodes of axilla and upper limb C81.35 Lymphocyte depleted classical Hodgkin lymphoma, lymph nodes of inguinal region and lower limb C81.36 Lymphocyte depleted classical Hodgkin lymphoma, intrapelvic lymph nodes C81.37 Lymphocyte depleted classical Hodgkin lymphoma, spleen C81.38 Lymphocyte depleted classical Hodgkin lymphoma, lymph nodes of multiple sites C81.39 Lymphocyte depleted classical Hodgkin lymphoma, extranodal and solid organ sites C81.40 Lymphocyte-rich classical Hodgkin lymphoma, unspecified site C81.41 Lymphocyte-rich classical Hodgkin lymphoma, lymph nodes of head, face, and neck C81.42 Lymphocyte-rich classical Hodgkin lymphoma, intrathoracic lymph nodes C81.43 Lymphocyte-rich classical Hodgkin lymphoma, intra-abdominal lymph nodes C81.44 Lymphocyte-rich classical Hodgkin lymphoma, lymph nodes of axilla and upper limb C81.45 Lymphocyte-rich classical Hodgkin lymphoma, lymph nodes of inguinal region and lower limb C81.46 Lymphocyte-rich classical Hodgkin lymphoma, intrapelvic lymph nodes

Page 8 of 23 C81.47 Lymphocyte-rich classical Hodgkin lymphoma, spleen C81.48 Lymphocyte-rich classical Hodgkin lymphoma, lymph nodes of multiple sites C81.49 Lymphocyte-rich classical Hodgkin lymphoma, extranodal and solid organ sites C81.70 Other classical Hodgkin lymphoma, unspecified site C81.71 Other classical Hodgkin lymphoma, lymph nodes of head, face, and neck C81.72 Other classical Hodgkin lymphoma, intrathoracic lymph nodes C81.73 Other classical Hodgkin lymphoma, intra-abdominal lymph nodes C81.74 Other classical Hodgkin lymphoma, lymph nodes of axilla and upper limb C81.75 Other classical Hodgkin lymphoma, lymph nodes of inguinal region and lower limb C81.76 Other classical Hodgkin lymphoma, intrapelvic lymph nodes C81.77 Other classical Hodgkin lymphoma, spleen C81.78 Other classical Hodgkin lymphoma, lymph nodes of multiple sites C81.79 Other classical Hodgkin lymphoma, extranodal and solid organ sites C81.90 Hodgkin lymphoma, unspecified, unspecified site C81.91 Hodgkin lymphoma, unspecified, lymph nodes of head, face, and neck C81.92 Hodgkin lymphoma, unspecified, intrathoracic lymph nodes C81.93 Hodgkin lymphoma, unspecified, intra-abdominal lymph nodes C81.94 Hodgkin lymphoma, unspecified, lymph nodes of axilla and upper limb C81.95 Hodgkin lymphoma, unspecified, lymph nodes of inguinal region and lower limb C81.96 Hodgkin lymphoma, unspecified, intrapelvic lymph nodes C81.97 Hodgkin lymphoma, unspecified, spleen C81.98 Hodgkin lymphoma, unspecified, lymph nodes of multiple sites C81.99 Hodgkin lymphoma, unspecified, extranodal and solid organ sites C82.00 Follicular lymphoma grade I, unspecified site C82.01 Follicular lymphoma grade I, lymph nodes of head, face, and neck C82.02 Follicular lymphoma grade I, intrathoracic lymph nodes C82.03 Follicular lymphoma grade I, intra-abdominal lymph nodes C82.04 Follicular lymphoma grade I, lymph nodes of axilla and upper limb C82.05 Follicular lymphoma grade I, lymph nodes of inguinal region and lower limb C82.06 Follicular lymphoma grade I, intrapelvic lymph nodes C82.07 Follicular lymphoma grade I, spleen C82.08 Follicular lymphoma grade I, lymph nodes of multiple sites C82.09 Follicular lymphoma grade I, extranodal and solid organ sites C82.10 Follicular lymphoma grade II, unspecified site C82.11 Follicular lymphoma grade II, lymph nodes of head, face, and neck C82.12 Follicular lymphoma grade II, intrathoracic lymph nodes C82.13 Follicular lymphoma grade II, intra-abdominal lymph nodes C82.14 Follicular lymphoma grade II, lymph nodes of axilla and upper limb

Page 9 of 23 C82.15 Follicular lymphoma grade II, lymph nodes of inguinal region and lower limb C82.16 Follicular lymphoma grade II, intrapelvic lymph nodes C82.17 Follicular lymphoma grade II, spleen C82.18 Follicular lymphoma grade II, lymph nodes of multiple sites C82.19 Follicular lymphoma grade II, extranodal and solid organ sites C82.20 Follicular lymphoma grade III, unspecified, unspecified site C82.21 Follicular lymphoma grade III, unspecified, lymph nodes of head, face, and neck C82.22 Follicular lymphoma grade III, unspecified, intrathoracic lymph nodes C82.23 Follicular lymphoma grade III, unspecified, intra-abdominal lymph nodes C82.24 Follicular lymphoma grade III, unspecified, lymph nodes of axilla and upper limb C82.25 Follicular lymphoma grade III, unspecified, lymph nodes of inguinal region and lower limb C82.26 Follicular lymphoma grade III, unspecified, intrapelvic lymph nodes C82.27 Follicular lymphoma grade III, unspecified, spleen C82.28 Follicular lymphoma grade III, unspecified, lymph nodes of multiple sites C82.29 Follicular lymphoma grade III, unspecified, extranodal and solid organ sites C82.30 Follicular lymphoma grade IIIa, unspecified site C82.31 Follicular lymphoma grade IIIa, lymph nodes of head, face, and neck C82.32 Follicular lymphoma grade IIIa, intrathoracic lymph nodes C82.33 Follicular lymphoma grade IIIa, intra-abdominal lymph nodes C82.34 Follicular lymphoma grade IIIa, lymph nodes of axilla and upper limb C82.35 Follicular lymphoma grade IIIa, lymph nodes of inguinal region and lower limb C82.36 Follicular lymphoma grade IIIa, intrapelvic lymph nodes C82.37 Follicular lymphoma grade IIIa, spleen C82.38 Follicular lymphoma grade IIIa, lymph nodes of multiple sites C82.39 Follicular lymphoma grade IIIa, extranodal and solid organ sites C82.40 Follicular lymphoma grade IIIb, unspecified site C82.41 Follicular lymphoma grade IIIb, lymph nodes of head, face, and neck C82.42 Follicular lymphoma grade IIIb, intrathoracic lymph nodes C82.43 Follicular lymphoma grade IIIb, intra-abdominal lymph nodes C82.44 Follicular lymphoma grade IIIb, lymph nodes of axilla and upper limb C82.45 Follicular lymphoma grade IIIb, lymph nodes of inguinal region and lower limb C82.46 Follicular lymphoma grade IIIb, intrapelvic lymph nodes C82.47 Follicular lymphoma grade IIIb, spleen C82.48 Follicular lymphoma grade IIIb, lymph nodes of multiple sites C82.49 Follicular lymphoma grade IIIb, extranodal and solid organ sites C82.50 Diffuse follicle center lymphoma, unspecified site

Page 10 of 23 C82.51 Diffuse follicle center lymphoma, lymph nodes of head, face, and neck C82.52 Diffuse follicle center lymphoma, intrathoracic lymph nodes C82.53 Diffuse follicle center lymphoma, intra-abdominal lymph nodes C82.54 Diffuse follicle center lymphoma, lymph nodes of axilla and upper limb C82.55 Diffuse follicle center lymphoma, lymph nodes of inguinal region and lower limb C82.56 Diffuse follicle center lymphoma, intrapelvic lymph nodes C82.57 Diffuse follicle center lymphoma, spleen C82.58 Diffuse follicle center lymphoma, lymph nodes of multiple sites C82.59 Diffuse follicle center lymphoma, extranodal and solid organ sites C82.60 Cutaneous follicle center lymphoma, unspecified site C82.61 Cutaneous follicle center lymphoma, lymph nodes of head, face, and neck C82.62 Cutaneous follicle center lymphoma, intrathoracic lymph nodes C82.63 Cutaneous follicle center lymphoma, intra-abdominal lymph nodes C82.64 Cutaneous follicle center lymphoma, lymph nodes of axilla and upper limb C82.65 Cutaneous follicle center lymphoma, lymph nodes of inguinal region and lower limb C82.66 Cutaneous follicle center lymphoma, intrapelvic lymph nodes C82.67 Cutaneous follicle center lymphoma, spleen C82.68 Cutaneous follicle center lymphoma, lymph nodes of multiple sites C82.69 Cutaneous follicle center lymphoma, extranodal and solid organ sites C82.80 Other types of follicular lymphoma, unspecified site C82.81 Other types of follicular lymphoma, lymph nodes of head, face, and neck C82.82 Other types of follicular lymphoma, intrathoracic lymph nodes C82.83 Other types of follicular lymphoma, intra-abdominal lymph nodes C82.84 Other types of follicular lymphoma, lymph nodes of axilla and upper limb C82.85 Other types of follicular lymphoma, lymph nodes of inguinal region and lower limb C82.86 Other types of follicular lymphoma, intrapelvic lymph nodes C82.87 Other types of follicular lymphoma, spleen C82.88 Other types of follicular lymphoma, lymph nodes of multiple sites C82.89 Other types of follicular lymphoma, extranodal and solid organ sites C82.90 Follicular lymphoma, unspecified, unspecified site C82.91 Follicular lymphoma, unspecified, lymph nodes of head, face, and neck C82.92 Follicular lymphoma, unspecified, intrathoracic lymph nodes C82.93 Follicular lymphoma, unspecified, intra-abdominal lymph nodes C82.94 Follicular lymphoma, unspecified, lymph nodes of axilla and upper limb C82.95 Follicular lymphoma, unspecified, lymph nodes of inguinal region and lower limb C82.96 Follicular lymphoma, unspecified, intrapelvic lymph nodes C82.97 Follicular lymphoma, unspecified, spleen

Page 11 of 23 C82.98 Follicular lymphoma, unspecified, lymph nodes of multiple sites C82.99 Follicular lymphoma, unspecified, extranodal and solid organ sites C83.00 Small cell B-cell lymphoma, unspecified site C83.01 Small cell B-cell lymphoma, lymph nodes of head, face, and neck C83.02 Small cell B-cell lymphoma, intrathoracic lymph nodes C83.03 Small cell B-cell lymphoma, intra-abdominal lymph nodes C83.04 Small cell B-cell lymphoma, lymph nodes of axilla and upper limb C83.05 Small cell B-cell lymphoma, lymph nodes of inguinal region and lower limb C83.06 Small cell B-cell lymphoma, intrapelvic lymph nodes C83.07 Small cell B-cell lymphoma, spleen C83.08 Small cell B-cell lymphoma, lymph nodes of multiple sites C83.09 Small cell B-cell lymphoma, extranodal and solid organ sites C83.10 Mantle cell lymphoma, unspecified site C83.11 Mantle cell lymphoma, lymph nodes of head, face, and neck C83.12 Mantle cell lymphoma, intrathoracic lymph nodes C83.13 Mantle cell lymphoma, intra-abdominal lymph nodes C83.14 Mantle cell lymphoma, lymph nodes of axilla and upper limb C83.15 Mantle cell lymphoma, lymph nodes of inguinal region and lower limb C83.16 Mantle cell lymphoma, intrapelvic lymph nodes C83.17 Mantle cell lymphoma, spleen C83.18 Mantle cell lymphoma, lymph nodes of multiple sites C83.19 Mantle cell lymphoma, extranodal and solid organ sites C83.30 Diffuse large B-cell lymphoma, unspecified site C83.31 Diffuse large B-cell lymphoma, lymph nodes of head, face, and neck C83.32 Diffuse large B-cell lymphoma, intrathoracic lymph nodes C83.33 Diffuse large B-cell lymphoma, intra-abdominal lymph nodes C83.34 Diffuse large B-cell lymphoma, lymph nodes of axilla and upper limb C83.35 Diffuse large B-cell lymphoma, lymph nodes of inguinal region and lower limb C83.36 Diffuse large B-cell lymphoma, intrapelvic lymph nodes C83.37 Diffuse large B-cell lymphoma, spleen C83.38 Diffuse large B-cell lymphoma, lymph nodes of multiple sites C83.39 Diffuse large B-cell lymphoma, extranodal and solid organ sites C83.50 Lymphoblastic (diffuse) lymphoma, unspecified site C83.51 Lymphoblastic (diffuse) lymphoma, lymph nodes of head, face, and neck C83.52 Lymphoblastic (diffuse) lymphoma, intrathoracic lymph nodes C83.53 Lymphoblastic (diffuse) lymphoma, intra-abdominal lymph nodes C83.54 Lymphoblastic (diffuse) lymphoma, lymph nodes of axilla and upper limb C83.55 Lymphoblastic (diffuse) lymphoma, lymph nodes of inguinal region and lower limb

Page 12 of 23 C83.56 Lymphoblastic (diffuse) lymphoma, intrapelvic lymph nodes C83.57 Lymphoblastic (diffuse) lymphoma, spleen C83.58 Lymphoblastic (diffuse) lymphoma, lymph nodes of multiple sites C83.59 Lymphoblastic (diffuse) lymphoma, extranodal and solid organ sites C83.70 Burkitt lymphoma, unspecified site C83.71 Burkitt lymphoma, lymph nodes of head, face, and neck C83.72 Burkitt lymphoma, intrathoracic lymph nodes C83.73 Burkitt lymphoma, intra-abdominal lymph nodes C83.74 Burkitt lymphoma, lymph nodes of axilla and upper limb C83.75 Burkitt lymphoma, lymph nodes of inguinal region and lower limb C83.76 Burkitt lymphoma, intrapelvic lymph nodes C83.77 Burkitt lymphoma, spleen C83.78 Burkitt lymphoma, lymph nodes of multiple sites C83.79 Burkitt lymphoma, extranodal and solid organ sites C83.80 Other non-follicular lymphoma, unspecified site C83.81 Other non-follicular lymphoma, lymph nodes of head, face, and neck C83.82 Other non-follicular lymphoma, intrathoracic lymph nodes C83.83 Other non-follicular lymphoma, intra-abdominal lymph nodes C83.84 Other non-follicular lymphoma, lymph nodes of axilla and upper limb C83.85 Other non-follicular lymphoma, lymph nodes of inguinal region and lower limb C83.86 Other non-follicular lymphoma, intrapelvic lymph nodes C83.87 Other non-follicular lymphoma, spleen C83.88 Other non-follicular lymphoma, lymph nodes of multiple sites C83.89 Other non-follicular lymphoma, extranodal and solid organ sites C83.90 Non-follicular (diffuse) lymphoma, unspecified, unspecified site C83.91 Non-follicular (diffuse) lymphoma, unspecified, lymph nodes of head, face, and neck C83.92 Non-follicular (diffuse) lymphoma, unspecified, intrathoracic lymph nodes C83.93 Non-follicular (diffuse) lymphoma, unspecified, intra-abdominal lymph nodes C83.94 Non-follicular (diffuse) lymphoma, unspecified, lymph nodes of axilla and upper limb C83.95 Non-follicular (diffuse) lymphoma, unspecified, lymph nodes of inguinal region and lower limb C83.96 Non-follicular (diffuse) lymphoma, unspecified, intrapelvic lymph nodes C83.97 Non-follicular (diffuse) lymphoma, unspecified, spleen C83.98 Non-follicular (diffuse) lymphoma, unspecified, lymph nodes of multiple sites C83.99 Non-follicular (diffuse) lymphoma, unspecified, extranodal and solid organ sites C84.60 Anaplastic large cell lymphoma, ALK-positive, unspecified site

Page 13 of 23 C84.61 Anaplastic large cell lymphoma, ALK-positive, lymph nodes of head, face, and neck C84.62 Anaplastic large cell lymphoma, ALK-positive, intrathoracic lymph nodes C84.63 Anaplastic large cell lymphoma, ALK-positive, intra-abdominal lymph nodes C84.64 Anaplastic large cell lymphoma, ALK-positive, lymph nodes of axilla and upper limb C84.65 Anaplastic large cell lymphoma, ALK-positive, lymph nodes of inguinal region and lower limb C84.66 Anaplastic large cell lymphoma, ALK-positive, intrapelvic lymph nodes C84.67 Anaplastic large cell lymphoma, ALK-positive, spleen C84.68 Anaplastic large cell lymphoma, ALK-positive, lymph nodes of multiple sites C84.69 Anaplastic large cell lymphoma, ALK-positive, extranodal and solid organ sites C84.70 Anaplastic large cell lymphoma, ALK-negative, unspecified site C84.71 Anaplastic large cell lymphoma, ALK-negative, lymph nodes of head, face, and neck C84.72 Anaplastic large cell lymphoma, ALK-negative, intrathoracic lymph nodes C84.73 Anaplastic large cell lymphoma, ALK-negative, intra-abdominal lymph nodes C84.74 Anaplastic large cell lymphoma, ALK-negative, lymph nodes of axilla and upper limb C84.75 Anaplastic large cell lymphoma, ALK-negative, lymph nodes of inguinal region and lower limb C84.76 Anaplastic large cell lymphoma, ALK-negative, intrapelvic lymph nodes C84.77 Anaplastic large cell lymphoma, ALK-negative, spleen C84.78 Anaplastic large cell lymphoma, ALK-negative, lymph nodes of multiple sites C84.79 Anaplastic large cell lymphoma, ALK-negative, extranodal and solid organ sites C84.90 Mature T/NK-cell lymphomas, unspecified, unspecified site C84.92 Mature T/NK-cell lymphomas, unspecified, intrathoracic lymph nodes C84.93 Mature T/NK-cell lymphomas, unspecified, intra-abdominal lymph nodes C84.94 Mature T/NK-cell lymphomas, unspecified, lymph nodes of axilla and upper limb C84.95 Mature T/NK-cell lymphomas, unspecified, lymph nodes of inguinal region and lower limb C84.96 Mature T/NK-cell lymphomas, unspecified, intrapelvic lymph nodes C84.97 Mature T/NK-cell lymphomas, unspecified, spleen C84.98 Mature T/NK-cell lymphomas, unspecified, lymph nodes of multiple sites C84.99 Mature T/NK-cell lymphomas, unspecified, extranodal and solid organ sites C84.A0 C84.A1 C84.A2 C84.A3 C84.A4 Cutaneous T-cell lymphoma, unspecified, unspecified site Cutaneous T-cell lymphoma, unspecified lymph nodes of head, face, and neck Cutaneous T-cell lymphoma, unspecified, intrathoracic lymph nodes Cutaneous T-cell lymphoma, unspecified, intra-abdominal lymph nodes Cutaneous T-cell lymphoma, unspecified, lymph nodes of axilla and upper limb

Page 14 of 23 C84.A5 C84.A6 C84.A7 C84.A8 C84.A9 C84.Z0 C84.Z1 C84.Z2 C84.Z3 C84.Z4 C84.Z5 C84.Z6 C84.Z7 C84.Z8 C84.Z9 Cutaneous T-cell lymphoma, unspecified, lymph nodes of inguinal region and lower limb Cutaneous T-cell lymphoma, unspecified, intrapelvic lymph nodes Cutaneous T-cell lymphoma, unspecified, spleen Cutaneous T-cell lymphoma, unspecified, lymph nodes of multiple sites Cutaneous T-cell lymphoma, unspecified, extranodal and solid organ sites Other mature T/NK-cell lymphomas, unspecified site Other mature T/NK-cell lymphomas, lymph nodes of head, face, and neck Other mature T/NK-cell lymphomas, intrathoracic lymph nodes Other mature T/NK-cell lymphomas, intra-abdominal lymph nodes Other mature T/NK-cell lymphomas, lymph nodes of axilla and upper limb Other mature T/NK-cell lymphomas, lymph nodes of inguinal region and lower limb Other mature T/NK-cell lymphomas, intrapelvic lymph nodes Other mature T/NK-cell lymphomas, spleen Other mature T/NK-cell lymphomas, lymph nodes of multiple sites Other mature T/NK-cell lymphomas, extranodal and solid organ sites C85.10 Unspecified B-cell lymphoma, unspecified site C85.11 Unspecified B-cell lymphoma, lymph nodes of head, face, and neck C85.12 Unspecified B-cell lymphoma, intrathoracic lymph nodes C85.13 Unspecified B-cell lymphoma, intra-abdominal lymph nodes C85.14 Unspecified B-cell lymphoma, lymph nodes of axilla and upper limb C85.15 Unspecified B-cell lymphoma, lymph nodes of inguinal region and lower limb C85.16 Unspecified B-cell lymphoma, intrapelvic lymph nodes C85.17 Unspecified B-cell lymphoma, spleen C85.18 Unspecified B-cell lymphoma, lymph nodes of multiple sites C85.19 Unspecified B-cell lymphoma, extranodal and solid organ sites C85.20 Mediastinal (thymic) large B-cell lymphoma, unspecified site C85.21 Mediastinal (thymic) large B-cell lymphoma, lymph nodes of head, face, and neck C85.22 Mediastinal (thymic) large B-cell lymphoma, intrathoracic lymph nodes C85.23 Mediastinal (thymic) large B-cell lymphoma, intra-abdominal lymph nodes C85.24 Mediastinal (thymic) large B-cell lymphoma, lymph nodes of axilla and upper limb C85.25 Mediastinal (thymic) large B-cell lymphoma, lymph nodes of inguinal region and lower limb C85.26 Mediastinal (thymic) large B-cell lymphoma, intrapelvic lymph nodes C85.27 Mediastinal (thymic) large B-cell lymphoma, spleen C85.28 Mediastinal (thymic) large B-cell lymphoma, lymph nodes of multiple sites C85.29 Mediastinal (thymic) large B-cell lymphoma, extranodal and solid organ sites C85.80 Other specified types of non-hodgkin lymphoma, unspecified site

Page 15 of 23 C85.81 Other specified types of non-hodgkin lymphoma, lymph nodes of head, face, and neck C85.82 Other specified types of non-hodgkin lymphoma, intrathoracic lymph nodes C85.83 Other specified types of non-hodgkin lymphoma, intra-abdominal lymph nodes C85.84 Other specified types of non-hodgkin lymphoma, lymph nodes of axilla and upper limb C85.85 Other specified types of non-hodgkin lymphoma, lymph nodes of inguinal region and lower limb C85.86 Other specified types of non-hodgkin lymphoma, intrapelvic lymph nodes C85.87 Other specified types of non-hodgkin lymphoma, spleen C85.88 Other specified types of non-hodgkin lymphoma, lymph nodes of multiple sites C85.89 Other specified types of non-hodgkin lymphoma, extranodal and solid organ sites C85.90 Non-Hodgkin lymphoma, unspecified, unspecified site C85.91 Non-Hodgkin lymphoma, unspecified, lymph nodes of head, face, and neck C85.92 Non-Hodgkin lymphoma, unspecified, intrathoracic lymph nodes C85.93 Non-Hodgkin lymphoma, unspecified, intra-abdominal lymph nodes C85.94 Non-Hodgkin lymphoma, unspecified, lymph nodes of axilla and upper limb C85.95 Non-Hodgkin lymphoma, unspecified, lymph nodes of inguinal region and lower limb C85.96 Non-Hodgkin lymphoma, unspecified, intrapelvic lymph nodes C85.97 Non-Hodgkin lymphoma, unspecified, spleen C85.98 Non-Hodgkin lymphoma, unspecified, lymph nodes of multiple sites C85.99 Non-Hodgkin lymphoma, unspecified, extranodal and solid organ sites C86.0 Extranodal NK/T-cell lymphoma, nasal type C86.1 Hepatosplenic T-cell lymphoma C86.2 Enteropathy-type (intestinal) T-cell lymphoma C86.3 Subcutaneous panniculitis-like T-cell lymphoma C86.4 Blastic NK-cell lymphoma C86.5 Angioimmunoblastic T-cell lymphoma C86.6 Primary cutaneous CD30-positive T-cell proliferations C88.0 Waldenstrom macroglobulinemia C88.4 Extranodal marginal zone B-cell lymphoma of mucosa-associated lymphoid tissue [MALT-lymphoma] C91.00 Acute lymphoblastic leukemia not having achieved remission C91.01 Acute lymphoblastic leukemia, in remission C91.02 Acute lymphoblastic leukemia, in relapse C91.10 Chronic lymphocytic leukemia of B-cell type not having achieved remission C91.11 Chronic lymphocytic leukemia of B-cell type in remission C91.12 Chronic lymphocytic leukemia of B-cell type in relapse C91.40 Hairy cell leukemia not having achieved remission

Page 16 of 23 C91.41 Hairy cell leukemia, in remission C91.42 Hairy cell leukemia, in relapse C96.4 Sarcoma of dendritic cells (accessory cells) C96.9 Malignant neoplasm of lymphoid, hematopoietic and related tissue, unspecified C96.Z Other specified malignant neoplasms of lymphoid, hematopoietic and related tissue D59.0 Drug-induced autoimmune hemolytic anemia D59.1 Other autoimmune hemolytic anemias D69.3 Immune thrombocytopenic purpura D69.41 Evans syndrome D69.42 Congenital and hereditary thrombocytopenia purpura D69.49 Other primary thrombocytopenia G35 Multiple sclerosis G36.0 Neuromyelitis optica [Devic] G37.0 Diffuse sclerosis of central nervous system G37.5 Concentric sclerosis [Balo] of central nervous system G60.8 Other hereditary and idiopathic neuropathies G61.89 Other inflammatory polyneuropathies G62.89 Other specified polyneuropathies G64 Other disorders of peripheral nervous system G70.00 Myasthenia gravis without (acute) exacerbation G70.01 Myasthenia gravis with (acute) exacerbation M05.011 Felty's syndrome, right shoulder M05.012 Felty's syndrome, left shoulder M05.021 Felty's syndrome, right elbow M05.022 Felty's syndrome, left elbow M05.031 Felty's syndrome, right wrist M05.032 Felty's syndrome, left wrist M05.041 Felty's syndrome, right hand M05.042 Felty's syndrome, left hand M05.051 Felty's syndrome, right hip M05.052 Felty's syndrome, left hip M05.061 Felty's syndrome, right knee M05.062 Felty's syndrome, left knee M05.071 Felty's syndrome, right ankle and foot M05.072 Felty's syndrome, left ankle and foot M05.09 Felty's syndrome, multiple sites M05.211 Rheumatoid vasculitis with rheumatoid arthritis of right shoulder M05.212 Rheumatoid vasculitis with rheumatoid arthritis of left shoulder

Page 17 of 23 M05.221 Rheumatoid vasculitis with rheumatoid arthritis of right elbow M05.222 Rheumatoid vasculitis with rheumatoid arthritis of left elbow M05.231 Rheumatoid vasculitis with rheumatoid arthritis of right wrist M05.232 Rheumatoid vasculitis with rheumatoid arthritis of left wrist M05.241 Rheumatoid vasculitis with rheumatoid arthritis of right hand M05.242 Rheumatoid vasculitis with rheumatoid arthritis of left hand M05.251 Rheumatoid vasculitis with rheumatoid arthritis of right hip M05.252 Rheumatoid vasculitis with rheumatoid arthritis of left hip M05.261 Rheumatoid vasculitis with rheumatoid arthritis of right knee M05.262 Rheumatoid vasculitis with rheumatoid arthritis of left knee M05.271 Rheumatoid vasculitis with rheumatoid arthritis of right ankle and foot M05.272 Rheumatoid vasculitis with rheumatoid arthritis of left ankle and foot M05.29 Rheumatoid vasculitis with rheumatoid arthritis of multiple sites M05.30 Rheumatoid heart disease with rheumatoid arthritis of unspecified site M05.312 Rheumatoid heart disease with rheumatoid arthritis of left shoulder M05.321 Rheumatoid heart disease with rheumatoid arthritis of right elbow M05.322 Rheumatoid heart disease with rheumatoid arthritis of left elbow M05.331 Rheumatoid heart disease with rheumatoid arthritis of right wrist M05.332 Rheumatoid heart disease with rheumatoid arthritis of left wrist M05.341 Rheumatoid heart disease with rheumatoid arthritis of right hand M05.342 Rheumatoid heart disease with rheumatoid arthritis of left hand M05.351 Rheumatoid heart disease with rheumatoid arthritis of right hip M05.352 Rheumatoid heart disease with rheumatoid arthritis of left hip M05.361 Rheumatoid heart disease with rheumatoid arthritis of right knee M05.362 Rheumatoid heart disease with rheumatoid arthritis of left knee M05.371 Rheumatoid heart disease with rheumatoid arthritis of right ankle and foot M05.372 Rheumatoid heart disease with rheumatoid arthritis of left ankle and foot M05.39 Rheumatoid heart disease with rheumatoid arthritis of multiple sites M05.411 Rheumatoid myopathy with rheumatoid arthritis of right shoulder M05.412 Rheumatoid myopathy with rheumatoid arthritis of left shoulder M05.421 Rheumatoid myopathy with rheumatoid arthritis of right elbow M05.422 Rheumatoid myopathy with rheumatoid arthritis of left elbow M05.431 Rheumatoid myopathy with rheumatoid arthritis of right wrist M05.432 Rheumatoid myopathy with rheumatoid arthritis of left wrist M05.441 Rheumatoid myopathy with rheumatoid arthritis of right hand M05.442 Rheumatoid myopathy with rheumatoid arthritis of left hand M05.451 Rheumatoid myopathy with rheumatoid arthritis of right hip M05.452 Rheumatoid myopathy with rheumatoid arthritis of left hip M05.461 Rheumatoid myopathy with rheumatoid arthritis of right knee

Page 18 of 23 M05.462 Rheumatoid myopathy with rheumatoid arthritis of left knee M05.471 Rheumatoid myopathy with rheumatoid arthritis of right ankle and foot M05.472 Rheumatoid myopathy with rheumatoid arthritis of left ankle and foot M05.49 Rheumatoid myopathy with rheumatoid arthritis of multiple sites M05.511 Rheumatoid polyneuropathy with rheumatoid arthritis of right shoulder M05.512 Rheumatoid polyneuropathy with rheumatoid arthritis of left shoulder M05.521 Rheumatoid polyneuropathy with rheumatoid arthritis of right elbow M05.522 Rheumatoid polyneuropathy with rheumatoid arthritis of left elbow M05.531 Rheumatoid polyneuropathy with rheumatoid arthritis of right wrist M05.532 Rheumatoid polyneuropathy with rheumatoid arthritis of left wrist M05.541 Rheumatoid polyneuropathy with rheumatoid arthritis of right hand M05.542 Rheumatoid polyneuropathy with rheumatoid arthritis of left hand M05.551 Rheumatoid polyneuropathy with rheumatoid arthritis of right hip M05.552 Rheumatoid polyneuropathy with rheumatoid arthritis of left hip M05.561 Rheumatoid polyneuropathy with rheumatoid arthritis of right knee M05.562 Rheumatoid polyneuropathy with rheumatoid arthritis of left knee M05.571 Rheumatoid polyneuropathy with rheumatoid arthritis of right ankle and foot M05.572 Rheumatoid polyneuropathy with rheumatoid arthritis of left ankle and foot M05.59 Rheumatoid polyneuropathy with rheumatoid arthritis of multiple sites M05.611 Rheumatoid arthritis of right shoulder with involvement of other organs and M05.612 Rheumatoid arthritis of left shoulder with involvement of other organs and M05.621 Rheumatoid arthritis of right elbow with involvement of other organs and M05.622 Rheumatoid arthritis of left elbow with involvement of other organs and M05.631 Rheumatoid arthritis of right wrist with involvement of other organs and M05.632 Rheumatoid arthritis of left wrist with involvement of other organs and M05.641 Rheumatoid arthritis of right hand with involvement of other organs and M05.642 Rheumatoid arthritis of left hand with involvement of other organs and M05.651 Rheumatoid arthritis of right hip with involvement of other organs and M05.652 Rheumatoid arthritis of left hip with involvement of other organs and M05.661 Rheumatoid arthritis of right knee with involvement of other organs and M05.662 Rheumatoid arthritis of left knee with involvement of other organs and M05.671 Rheumatoid arthritis of right ankle and foot with involvement of other organs and

Page 19 of 23 M05.672 Rheumatoid arthritis of left ankle and foot with involvement of other organs and M05.69 Rheumatoid arthritis of multiple sites with involvement of other organs and M05.711 Rheumatoid arthritis with rheumatoid factor of right shoulder without organ or involvement M05.712 Rheumatoid arthritis with rheumatoid factor of left shoulder without organ or involvement M05.721 Rheumatoid arthritis with rheumatoid factor of right elbow without organ or involvement M05.722 Rheumatoid arthritis with rheumatoid factor of left elbow without organ or involvement M05.731 Rheumatoid arthritis with rheumatoid factor of right wrist without organ or involvement M05.732 Rheumatoid arthritis with rheumatoid factor of left wrist without organ or involvement M05.741 Rheumatoid arthritis with rheumatoid factor of right hand without organ or involvement M05.742 Rheumatoid arthritis with rheumatoid factor of left hand without organ or involvement M05.751 Rheumatoid arthritis with rheumatoid factor of right hip without organ or involvement M05.752 Rheumatoid arthritis with rheumatoid factor of left hip without organ or involvement M05.761 Rheumatoid arthritis with rheumatoid factor of right knee without organ or involvement M05.762 Rheumatoid arthritis with rheumatoid factor of left knee without organ or involvement M05.771 Rheumatoid arthritis with rheumatoid factor of right ankle and foot without organ or involvement M05.772 Rheumatoid arthritis with rheumatoid factor of left ankle and foot without organ or involvement M05.79 Rheumatoid arthritis with rheumatoid factor of multiple sites without organ or involvement M05.811 Other rheumatoid arthritis with rheumatoid factor of right shoulder M05.812 Other rheumatoid arthritis with rheumatoid factor of left shoulder M05.821 Other rheumatoid arthritis with rheumatoid factor of right elbow M05.822 Other rheumatoid arthritis with rheumatoid factor of left elbow M05.831 Other rheumatoid arthritis with rheumatoid factor of right wrist M05.832 Other rheumatoid arthritis with rheumatoid factor of left wrist M05.841 Other rheumatoid arthritis with rheumatoid factor of right hand M05.842 Other rheumatoid arthritis with rheumatoid factor of left hand M05.851 Other rheumatoid arthritis with rheumatoid factor of right hip M05.852 Other rheumatoid arthritis with rheumatoid factor of left hip M05.861 Other rheumatoid arthritis with rheumatoid factor of right knee M05.862 Other rheumatoid arthritis with rheumatoid factor of left knee M05.871 Other rheumatoid arthritis with rheumatoid factor of right ankle and foot

Page 20 of 23 M05.872 Other rheumatoid arthritis with rheumatoid factor of left ankle and foot M05.89 Other rheumatoid arthritis with rheumatoid factor of multiple sites M05.9 Rheumatoid arthritis with rheumatoid factor, unspecified M06.011 Rheumatoid arthritis without rheumatoid factor, right shoulder M06.012 Rheumatoid arthritis without rheumatoid factor, left shoulder M06.021 Rheumatoid arthritis without rheumatoid factor, right elbow M06.022 Rheumatoid arthritis without rheumatoid factor, left elbow M06.031 Rheumatoid arthritis without rheumatoid factor, right wrist M06.032 Rheumatoid arthritis without rheumatoid factor, left wrist M06.041 Rheumatoid arthritis without rheumatoid factor, right hand M06.042 Rheumatoid arthritis without rheumatoid factor, left hand M06.051 Rheumatoid arthritis without rheumatoid factor, right hip M06.052 Rheumatoid arthritis without rheumatoid factor, left hip M06.061 Rheumatoid arthritis without rheumatoid factor, right knee M06.062 Rheumatoid arthritis without rheumatoid factor, left knee M06.071 Rheumatoid arthritis without rheumatoid factor, right ankle and foot M06.072 Rheumatoid arthritis without rheumatoid factor, left ankle and foot M06.08 Rheumatoid arthritis without rheumatoid factor, vertebrae M06.09 Rheumatoid arthritis without rheumatoid factor, multiple sites M06.1 Adult-onset Still's disease M06.211 Rheumatoid bursitis, right shoulder M06.212 Rheumatoid bursitis, left shoulder M06.221 Rheumatoid bursitis, right elbow M06.222 Rheumatoid bursitis, left elbow M06.231 Rheumatoid bursitis, right wrist M06.232 Rheumatoid bursitis, left wrist M06.241 Rheumatoid bursitis, right hand M06.242 Rheumatoid bursitis, left hand M06.251 Rheumatoid bursitis, right hip M06.252 Rheumatoid bursitis, left hip M06.261 Rheumatoid bursitis, right knee M06.262 Rheumatoid bursitis, left knee M06.271 Rheumatoid bursitis, right ankle and foot M06.272 Rheumatoid bursitis, left ankle and foot M06.28 Rheumatoid bursitis, vertebrae M06.29 Rheumatoid bursitis, multiple sites M06.311 Rheumatoid nodule, right shoulder M06.312 Rheumatoid nodule, left shoulder M06.321 Rheumatoid nodule, right elbow

Page 21 of 23 M06.322 Rheumatoid nodule, left elbow M06.331 Rheumatoid nodule, right wrist M06.332 Rheumatoid nodule, left wrist M06.341 Rheumatoid nodule, right hand M06.342 Rheumatoid nodule, left hand M06.351 Rheumatoid nodule, right hip M06.352 Rheumatoid nodule, left hip M06.361 Rheumatoid nodule, right knee M06.362 Rheumatoid nodule, left knee M06.371 Rheumatoid nodule, right ankle and foot M06.372 Rheumatoid nodule, left ankle and foot M06.38 Rheumatoid nodule, vertebrae M06.39 Rheumatoid nodule, multiple sites M06.811 Other specified rheumatoid arthritis, right shoulder M06.812 Other specified rheumatoid arthritis, left shoulder M06.821 Other specified rheumatoid arthritis, right elbow M06.822 Other specified rheumatoid arthritis, left elbow M06.831 Other specified rheumatoid arthritis, right wrist M06.832 Other specified rheumatoid arthritis, left wrist M06.841 Other specified rheumatoid arthritis, right hand M06.842 Other specified rheumatoid arthritis, left hand M06.851 Other specified rheumatoid arthritis, right hip M06.852 Other specified rheumatoid arthritis, left hip M06.861 Other specified rheumatoid arthritis, right knee M06.862 Other specified rheumatoid arthritis, left knee M06.871 Other specified rheumatoid arthritis, right ankle and foot M06.872 Other specified rheumatoid arthritis, left ankle and foot M06.88 Other specified rheumatoid arthritis, vertebrae M06.89 Other specified rheumatoid arthritis, multiple sites M06.9 Rheumatoid arthritis, unspecified M30.0 Polyarteritis nodosa M30.1 Polyarteritis with lung involvement [Churg-Strauss] M30.2 Juvenile polyarteritis M30.8 Other conditions related to polyarteritis nodosa M31.1 Thrombotic microangiopathy M31.30 Wegener's granulomatosis without renal involvement M31.31 Wegener's granulomatosis with renal involvement M31.7 Microscopic polyangiitis M33.20 Polymyositis, organ involvement unspecified

Page 22 of 23 M33.21 Polymyositis with respiratory involvement M33.22 Polymyositis with myopathy M33.29 Polymyositis with other organ involvement M35.00 Sicca syndrome, unspecified M35.01 Sicca syndrome with keratoconjunctivitis M35.02 Sicca syndrome with lung involvement M35.03 Sicca syndrome with myopathy M35.04 Sicca syndrome with tubulo-interstitial nephropathy M35.09 Sicca syndrome with other organ involvement ICD-10 Codes that DO NOT Support Medical Necessity Note: Performance is optimized by using code ranges. Additional ICD- 10 Information Associated Documents Attachments There are no attachments for this LCD Related Local Coverage Documents Related National Coverage Documents All Versions This LCD version has no Related Local Coverage Documents. This LCD version has no Related National Coverage Documents. Version 2 - Updated on 04/01/2014 08:55:27 with effective dates 10/01/2014 - N/A (Approved). Version 1 - Updated on 03/31/2014 15:19:42, by Tiffany Stamps, with effective dates 10/01/2014 - N/A. Additional Information Contractor Only Notes Keywords Rituximab Saved By Antonietta Sculimbrene Saved On 04/01/2014 08:55:27 THIS IS A PROPOSED/DRAFT LCD Close