Eastern North Carolina Lung Cancer Symposium

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Eastern North Carolina Lung Cancer Symposium Friday, November 3, 2017 The East Carolina Heart Institute 115 Heart Drive, Greenville, NC Jointly provided by: The Department of Internal Medicine and the Office of Continuing Medical Education of The Brody School of Medicine at East Carolina University UNC Eshelman School of Pharmacy In association with the Eastern Area Health Education Center Illustration: Alan Branigan

Program Description Lung cancer is the leading cause of cancer death in both men and women in the state of North Carolina and the United States. Every day 438 Americans will die from lung cancer: one American death from lung cancer will occur every 3 minutes and 20 seconds, of every single day, of every single month, of the entire year. This conference aims to provide the most current advances and practical information on the screening, diagnosis, and treatment of lung cancer. Designed to help you understand the options that are available for all patients, both surgical and nonsurgical, this conference will address dilemmas faced by thoracic oncologists for lung cancer treatment. This information will also help the primary care provider to become part of the treatment team for their patients with lung cancer. Lectures, discussion periods and a Molecular Lung Cancer Tumor Board will offer opportunities for both formal and informal exchanges between faculty and participants, and a comprehensive course e-syllabus will provide useful information and references for future practice. The keynote Jon Moran Lung Cancer Lectureship is named in honor of Dr. Jon Moran who was the iconic pioneer of lung cancer surgery at the Brody School of Medicine and in eastern North Carolina. Past Honorees: 2014 Dr. Sharon Ben-Or The Management of Occult N2 Disease 2015 Dr. Julian Rosenman The Outcome Plateau in Stage III Lung Cancer Time for a New Strategy 2016 Dr. Mark Bowling Interventional Pulmonology: The Fourth Pillar of Thoracic Oncology Who Should Attend This conference has been planned for Physicians, Nurse Practitioners, Pharmacists, Physician Assistants and Registered Nurses, particularly those in the fields of Primary Care, Family Medicine, Internal Medicine, Pulmonary Medicine and Oncology. ACCREDITATION: This activity has been planned and implemented in accordance with the accreditation requirements and policies of the Accreditation Council for Continuing Medical Education (ACCME) through the joint providership of The Department of Internal Medicine and the Office of Continuing Medical Education of The Brody School of Medicine of East Carolina University, UNC Eshelman School of Pharmacy and Eastern Area Health Education Center. CREDIT: The Brody School of Medicine of East Carolina University designates this live activity for a maximum of 6.5 AMA PRA Category 1 Credits. Physicians should claim only those credits commensurate with the extent of their participation in the activity. CONTACT HOURS: Certificates reflecting 6.5 contact hours of education will be awarded at the completion of the program. PHARMACISTS This program, ACPE# 0046-9999-17-286-L01-P will provide 6.5 contact hours of continuing pharmacy education credit for full-program participation. To receive CE credit, attendance must be acknowledged at the registration desk upon arrival at the program. Participants must attend the entire session to receive CE credit. Statements of credit can be viewed and printed from CPE Monitor. The University of North Carolina Eshelman School of Pharmacy is accredited by the Accreditation Council for Pharmacy Education as a provider of continuing pharmacy education.

Course Content Upon completion of this knowledge-based program the participant should be able to integrate new developments in the following areas into practice: Racial Disparity in the Management of Lung Cancer Review the historical racial disparity data in the treatment of lung cancer. Identify an intervention strategy to reduce the racial disparity in the treatment of lung cancer. Discuss the results of a study that reduced the racial disparity in the treatment of lung cancer. Clinical Care Pathways in the Management of Lung Cancer Review the purpose and clinical importance of clinical care pathways in lung cancer. Outline the implementation of clinical care pathways within a regional health system. Discuss the impact of clinical care pathways in the outcome of lung cancer treatment. How I Treat: Malignant Pleural Effusions Review the diagnosis and clinical impact of malignant pleural effusion. Outline potential therapeutic approaches in the management of malignant pleural effusions. Discuss the thoracic surgical approach of managing malignant pleural effusions. New FDA Approved Drugs in the Treatment of Lung Cancer Review the new FDA approved drugs in the treatment of lung cancer over the past year. Discuss the mechanism of actions of these newly approved agents in the treatment of lung cancer. Outline the clinical use of newer targeted and immune therapies in lung cancer. A Debate: Smoking with Lung Cancer Treatment---Does it matter?... Yay or Nay? Review the data of how smoking impacts lung cancer treatment. Identify certain subsets of patients where smoking can be favorable with ongoing lung cancer treatment. Discuss the perspectives of a thoracic medical oncologist and a thoracic surgical oncologist and smoking with lung cancer treatment. How I Treat: Esophageal Cancer Review the epidemiology of esophageal cancers. Outline the needed multimodality workup and treatment for esophageal cancer. Discuss the foregut surgical specialist approach to treating esophageal cancers. Pulmonary Sarcomatoid and Large Cell Neuroendocrine Lung Carcinomas: Histology Tumors into Biology Reviews the morphologic basis of diagnosis pulmonary sarcomatoid and large cell neuroendocrine lung cancers. Outline the molecular basis of lung cancer beyond morphology. Discuss the molecular tumor biology of pulmonary sarcomatoid and large cell neuroendocrine lung cancers. Impact of Lung Cancer Screening at the Outer Banks Hospital Review the proven lung cancer death benefit of low-dose CT lung screening. Outline the implementation of a lung cancer screening at a community hospital. Discuss patient outcome and financial impact of lung cancer screening at the Outer Banks Hospital. Immune Therapy in Early Stage Lung Cancer Review the clinic benefit of immune therapy in advanced stage lung cancers. Discuss the studies of immune therapy in early stage lung cancer. Outline an approach of integrating immune therapy in early stage lung cancers. Molecular Tumor Board Analyze patient cases to emphasize the molecular tumor biology treatment approach in lung cancer. Participate in interactive discussion of integrating these approaches into individual patient care management and decision making.

Agenda Eastern North Carolina Lung Cancer Symposium Friday, November 3, 2017 Moderator: Paul R. Walker, MD, FACP 7:30 Registration/Breakfast 8:10 Welcome/Overview 8:20 Keynote: The Jon Moran Lung Cancer Lectureship Racial Disparity in the Treatment of Lung Cancer Sam Cykert, MD 9:05 Clinical Care Pathways in the Treatment of Lung Cancer Mark Bowling, MD 9:45 How I Treat: Malignant Pleural Effusions Aundrea Oliver, MD 10:15 Break 10:35 New FDA Approved Drugs in the Treatment of Lung Cancer Evelina Kolychev, PharmD 11:05 A Debate: Smoking with Lung Cancer Treatment Does it matter? Yay or Nay? Nay, it does not matter! Paul Walker, MD, FACP Yay, it does matter! Mark Iannettoni, MD 11:45 Lunch 12:45 How I Treat: Esophageal Cancer Carlos Anciano, MD 1:25 Pulmonary Sarcomatoid and Large Cell Neuroendocrine Lung Carcinomas: Histology Tumors into Biology Gina Murray, MD 2:05 Impact of Lung Cancer Screening at The Outer Banks Hospital Charles Shelton, MD 2:35 Break 2:55 Immune Therapy in Early Stage Lung Cancer Paul Walker, MD, FACP 3:30 Molecular Tumor Board Moderator: Nitika Sharma, MD 4:30 Questions/Adjourn

Faculty PROGRAM DIRECTORS Mark R. Bowling, MD, FCCP Paul R. and Kathryn M. Hettinger Walker Distinguished Professorship of Clinical Oncology Associate Chair of Internal Medicine for Clinical Affairs Director of Interventional Pulmonology Director of Pulmonary Diagnostics at Vidant Health Brody School of Medicine Paul R. Walker, MD, FACP Chief, Hematology/Oncology Program Director, Hematology/Oncology Fellowship Brody School of Medicine GUEST FACULTY Samuel Cykert, MD Professor of Medicine, Clinician and Researcher, Division of General Medicine & Clinical Epidemiology; Associate Director of Medical Education for NC AHEC Program; Clinical Director of the NC Regional Extension Center for Health Information Technology University of North Carolina School of Medicine Evelina Kolychev, PharmD, BCOP Clinical Pharmacy Specialist-Hematology/Oncology Vidant Medical Center Nitika Sharma, MD Medical Oncology, Thoracic Oncology Program Leo Jenkins Cancer Center Charles Shelton, MD Radiation Oncology The Outer Banks Hospital Radiation Therapy Center BSOM FACULTY Carlos J. Anciano, MD Assistant Professor Thoracic & Foregut Surgery Director of Minimally Invasive Thoracic Surgery Department of Cardiovascular Sciences Mark D. Iannettoni, MD MBA W. Randolph Chitwood, Jr, MD, Distinguished Chair Chair, Department of Cardiovascular Sciences Chief, Cardiovascular Service line, Vidant Health Professor and Chief, Division of Thoracic Surgery Program Director, Thoracic Surgery Residency Gina Murray, MD Clinical Assistant Professor Department of Pathology Aundrea L. Oliver, MD Assistant Professor Division of Thoracic Surgery

Nearby Lodging Candlewood Suites 1055 Waterford Commons Drive, Greenville, NC (252-317-3000) Holiday Inn Express 900 Moye Blvd. Greenville, NC (252-754-8300) Courtyard by Marriott 2225 Stantonsburg Road Greenville, NC (252-329-2900) Registration Information PREREGISTRATION AND FEE PAYMENT IS REQUIRED. Advance payment of fee is necessary to guarantee space. Registration fee includes educational sessions, breaks, lunch, and an e-syllabus. Registration Fees Physicians/PharmDs/Other Doctorates $125.00 Other Health Care Professionals $75.00 Residents/Medical Students $50.00 Registration is available online only at www.easternahec.net Eastern AHEC Cancellation Policy To be eligible for a refund, cancellations MUST be emailed to easternahec@ecu.edu at least one week in advance of the activity. No refunds will be given for cancellations less than one week prior to activity. For continuing professional development activities canceled more than one week prior to continuing professional development activity, A $35.00 cancellation fee will be deducted from the refund, OR The registrant may elect to apply the full amount toward a future Eastern AHEC continuing professional development activity being held within one year, OR Substitutions are welcome; advance notification encouraged. Please be sure to bring a sweater or jacket for your comfort throughout the symposium. A letter of confirmation which includes a link to a map and e-syllabus will be emailed approximately one week prior to the program date. Please be sure that we have a current email address for you upon registration in order to receive all follow-up course information. Hard copies will not be available. Please see registration information for further details. You may make any changes to your contact information by visiting MYAHEC at my.ncahec.net. My AHEC will allow you to set up an account to update personal information at any time as well as track your credit record. By attending this event, I acknowledge that Eastern AHEC staff and/or their designees including news media may take general (not close-up) photos or videos of this event for marketing/publicity purposes, and I further allow my likeness to be used in this manner. If I do not wish to appear in these photos or videos, I understand that it is my responsibility to notify Eastern AHEC staff so my preference can be met. Americans with Disabilities Act Individuals requesting accommodation under the Americans with Disabilities Act (ADA) should contact the Department of Disability Support Services at (252) 737-1016 (V/TTY) at least five business days prior to the program. For further assistance, please call Angie Campbell at 252.744.5208 or email at mcarthura@ecu.edu.