New Delhi International Ministerial Conference on Avian and Pandemic Influenza Dec 4-6th, 2007 Session IV Influenza Pandemic Preparedness Dr Paul R Gully Health Security and Environment, Geneva
Avian Influenza and Pandemic Influenza H5N1 infection in poultry continues to lead to human infections with a high mortality rate A novel virus will lead to a pandemic of influenza The novel virus may or may not be H5N1 We have to be prepared for a pandemic, whenever, wherever it starts and from whatever cause 2
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Cumulative Number of Confirmed Human Cases of H5N1 Reported to WHO As of 12 November 2007 Country 2007 Total '03-07 cases deaths cases deaths Azerbaijan 0 0 8 5 Cambodia 1 1 7 7 China 3 2 25 16 Djibouti 0 0 1 0 Egypt 20 5 38 15 Indonesia 38 33 113 91 Iraq 0 0 3 2 Lao PDR 2 2 2 2 Nigeria 1 1 1 1 Thailand 0 0 25 17 Turkey 0 0 12 4 Viet Nam 7 4 100 46 Total 72 48 335 206 5
Technical Workshop on Highly Pathogenic Avian Influenza and Human H5N1 Infection Rome, June 2007 Country plans may not extend to the local level Surveillance and diagnostic capacity is still weak Response capacity can be useful for many other emergency situations. Developing countries need tools to be tailored to their local situations Merit in establishing a country-by-country approach 6
Further Analysis Focus on pandemic preparedness is increasing national and international capacity to detect, respond, plan and maintain systems for all health threats and other crises Investment should not detract from other disease programmes Need to maintain attention on current threats such as avian influenza as examples of threats to health security which will continue to arise Multi-sectoral approach to pandemic preparedness across both governments and society seem to be increasing credibility of this approach 7
Further Advances The Global Pandemic Influenza Action Plan (GAP) to increase vaccine supply: 1st meeting of a WHO Advisory Group for GAP, October 2007 Confirmed the current directions WHO setting up a training hub to promote technology transfer in developing countries by 2012, the expected supply-demand gap will be bridged The Strategic Advisory Group of Experts on immunization (SAGE) Recommended WHO stockpile up to 150 million doses of H5N1 influenza vaccine 1/3 for rapid containment 2/3 for low and middle income countries in the event of a pandemic caused by H5N1. 8
Further Action 1 Global consultations on preparedness guidelines, disease control measures and surveillance Rapid Containment workshops Development and testing of plans Different regional approaches e.g., WPRO & AFRO AFRO - 42/46 Member States developed and carried out training WPRO - June 2007, 46 countries surveyed: general lack of preparedness PAHO most countries have adapted and "nationalized" a generic Protocol for Surveillance and are adjusting plans following use of PAHO self-assessment tool 9
Further Action 2 Event management and further development of partnerships e.g., GOARN Advocacy for and guidance on strategies for community mitigation Promotion of integration of pandemic preparedness priorities within broader public health initiatives Continuation of close work relationship with UN and NGO partners 10
Further Action 3 Enhance the Global Influenza Surveillance Network Develop and H5N1 vaccine stockpile according the SAGE recommendations Explore pandemic vaccine supply options Continue to advance the Global Action Plan Promote capacity to respond in humanitarian events and across all sectors 11