CONTACT INFORMATION: Site Selection and Information: Bobbie Theodore, Site Liaison Tel. (916) 939-6696 Fax (208) 575-3169 Email: clinicaltrials@alliancesites.com EDUCATION: David B. Weiss, M.D., F.A.P.A. Clinical Trials of the Rockies 3955 E. Exposition Avenue, Suite 100 Denver, CO 80209 Tel. 303-919-3846 1985-1989 Doctor of Medicine University of Colorado Health Sciences Center, Denver, CO 1982-1985 BA with Distinction in Molecular Biology University of Colorado, Boulder, CO INTERNSHIP and RESIDENCY: 1994-1995 Chief Resident Department of Psychiatry, Denver General Hospital, Denver, CO 1992-1995 Psychiatry Resident University of Colorado Health Sciences Center, Denver, CO 1991-1992 Radiology Resident Presbyterian/ St. Luke's Medical Center, Denver, CO 1989-1990 Internship Presbyterian/ St. Luke's Medical Center, Denver, CO CERTIFICATIONS & LICENCES: Colorado Medical License Current DEA License Current Re-Certification by American Board of Psychiatry and Neurology 2007-present Board Certified by American Board of Psychiatry and Neurology 1997-2007 Diplomate National Board of Medical Examiners 1990-present 1
PROFESSIONAL SOCIETIES: American Psychiatric Association Colorado Psychiatric Society INVESTIGATOR EXPERIENCE: Addictions Depression Eating Disorders Hyertriglyceridemia Schizophrenia PROFESSIONAL EXPERIENCE: Partner and Principal Investigator, 2015 - present Clinical Trials of the Rockies Lytle and Weiss, PLLC Partnering with Mountain View Clinical Research, Inc., Denver, CO Chief of Staff, Attending Psychiatrist, 2010 - present Highlands Behavioral Health System, Littleton, CO Investigator, 2012-2015 Western Affiliated Research Institute, Denver, CO Medical Director, 2010-2012 Highlands Behavioral Health System, Littleton, CO Medical Advisor, 2004 - present CHG, Salt Lake City, UT Attending Psychiatrist, 2004-2010 Denver Health Medical Center, Denver, CO Contract Psychiatrist, 2002-2004 Locum Tenens Psychiatrist, Pueblo, CO, Phoenix, AZ Chief Operating Officer, Clinician, 1999-2002 TriHealth Solutions, Inc., Denver, CO Co-Medical Director, 1997-1999 Pathmakers of Colorado, Inc., Denver,CO Attending Psychiatrist Merit, 1997-1998 Merit Behavioral Care, Denver, CO Attending Psychiatrist, 1996-1997 Ft. Logan Mental Health Institute, Denver, CO 2
PROFESSIONAL EXPERIENCE (continued): Consulting Psychiatrist, 1995-1997 Vencor Hospital, Denver, CO Medical Director, 1995-1996 Asian/ Pacific Mental Health Center, Denver, CO Attending Psychiatrist, 1995-1996 Denver General Hospital Psychiatric Emergency Room, Denver, CO Medical Staff Physician, 1990-1991 Ft. Logan Mental Health Institute, Denver, CO CLINICAL TRIAL EXPERIENCE: Addiction A Phase IV, Non-Treatment Follow-Up for Cardiac Assessments Following Use of Smoking Cessation Treatments in Subjects With and Without a History of Psychiatric Disorders. A Phase IV, Randomized, Double-Blind, Active and Placebo-Controlled, Multicenter Study Evaluating the Neuropsychiatric Safety and Efficacy of 12 Weeks XXX and XXX for Smoking Cessation in Subjects With and Without a History of Psychiatric Disorders. Depression A Phase III, Multicenter Randomized, Double-blind, Placebo-controlled Trial of the Safety and Efficacy of Fixed-dose XXX as Adjunctive Therapy in the Treatment of Adults with Major Depressive Disorder With and Without Anxious Distress. A Phase III, Multicenter Study of the Long-term Safety and Tolerability of XXX for the Adjunctive Treatment of Major Depressive Disorder in Adults who Have an Inadequate Response to Antidepressant Therapy. A Phase III, Efficacy and Safety Study of XXX for the Adjunctive Treatment of Major Depressive Disorders. Interventional, Open-Label, Long-Term, Extension Study to Evaluate the Safety and Tolerability of XXX as Adjunctive Treatment in Patients with Major Depressive Disorder. Interventional, Randomized, Double-Blind, Parallel-Group, Placebo-Controlled, Fixed-Dose, Study to Evaluate the Efficacy and Safety of XXX as Adjunctive Treatment in Elderly Patients with Major Depressive Disorder with an Inadequate Response to Antidepressant Treatment. 3
CLINICAL TRIAL EXPERIENCE (continued): Interventional, Open-Label, Flexible-Dose, Exploratory Study of XXX as Adjunctive Treatment of Irritability in Patients with Major Depressive Disorder and an Inadequate Response to Antidepressant Therapy. A Phase III, Open-label, Multicenter, 12-month Extension Safety and Tolerability Study of XXX in Combination with XXX in the Treatment of Adults with Major Depressive Disorder with Residual Symptoms or Inadequate Response Following Treatment with an Antidepressant. A Phase II, Multicenter, Double-Blind, Parallel-group, Randomized, Placebo-controlled, Forced-dose Titration, Dose-ranging Efficacy and Safety Study of XXX in Combination with XXX in the Treatment of Adults with Major Depressive Disorder with Inadequate Response to Prospective Treatment with an Antidepressant. A Multicenter, Double-Blind, 58-week Rollover Study to assess the Safety and Tolerability of XXX in Patients with Treatment Resistant Major Depression. A Multicenter, Randomized, Double-blind, Active-Controlled, Comparative, Fixed-Dose, Dose Response Study of the Efficacy and Safety of XXX in Patients with Treatment Resistant Major Depression. A Multicenter, Randomized, Double-Blind, Placebo-Controlled, Parallel-Group Study to Evaluate the Efficacy and Safety of 2 Fixed Doses of XXX in Adult Outpatients with Major Depressive Disorder. A Double-Blind, Placebo-Controlled Study of the Efficacy and Safety of XXX vs. Placebo in the Treatment of Psychotic Symptoms in Patients with Major Depressive Disorder with Psychotic Features. Eating Disorders A Phase III, Multicenter, Open-Label, 12 month Extension Safety and Tolerability Study of XXX in the Treatment of Adults with Binge Eating Disorder. Other Indications Long-Term Outcomes Study to Assess Statin Residual Risk Reduction with XXX in High Cardiovascular Risk Patients with Hyertriglyceridemia. Schizophrenia A Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Efficacy and Safety of XXX in Acutely Psychotic Subjects with Schizophrenia. 4
CLINICAL TRIAL EXPERIENCE (continued): A 12-week, Phase III, Multicenter, Randomized, Double-blind, Placebo-controlled Trial of XXX Intramuscular Depot in the Acute Treatment of Adults with Schizophrenia. COMMITTEE APPOINTMENTS: Member, Outpatient Task Force Committee, Highlands Behavioral Hospital 2012-2014 Member, Board of Directors, Highlands Behavioral Hospital 2010-2012 Co-Chair, Committee of the Whole, Highlands Behavioral Hospital 2010-2012 Chair, Medical Executive Committee, Highlands Behavioral Hospital Member, Peer Review Committee, Highlands Behavioral Hospital 2010-present 2010-present Member, Psychiatry Pharmacy RIE, Denver Health Medical Center 2009 Member, Behavioral Health ValueStream Committee Denver Health Medical Center 2008 Member, Psychiatric Emergency Room RIE, Denver Health Medical Center 2007 Co-Chair, Psychiatric Emergency Room Admissions and Flow Committee Denver Health Medical Center 2006-2009 Member, Residency Education Committee, UCHSC, Department of Psychiatry 2004-2009 Member, Residency Call Committee, UCHSC, Department of Psychiatry 2004-2009 Member, Residency Selection Committee, UCHSC, Department of Psychiatry 2004-2009 Member, Behavioral Health QI Committee, United Health Care of Colorado 2000-2001 Member, Utilization Management Review Committee PacifiCare Behavioral Health, Inc. 1998-1999 Co-Chair, Quality Management Committee, Pathmakers of Colorado 1998-1999 Member, Medical Advisory Board, Pathmakers of Colorado 1998-1999 Member, Public Information and Education Committee Colorado Psychiatric Society 1994-1995 Member, Resident Crisis Assistance Network, UCHSC, Department of Psychiatry 1994-1995 5
COMMITTEE APPOINTMENTS (continued): Member, Residency Advocacy Group, UCHSC, Department of Psychiatry 1994-1995 Chair, Denver General Hospital, Department of Psychiatry Administrative Reviews 1994-1995 Chair, Denver General Hospital, Department of Psychiatry Bed Control Committee 1994-1995 Chair, Denver General Hospital, Psychiatry Morbidity & Mortality Conference Committee 1994-1995 FACULTY APPOINTMENTS: Assistant Clinical Professor, Rocky Vista University, Parker, CO 2012-present Assistant Professor, Department of Psychiatry, UCHSC, Denver, CO 2004-2010 Instructor. Department of Psychiatry, UCHSC, Denver, CO 1995-1998 TEACHING APPOINTMENTS: Clinical Faculty Supervisor, third and fourth year medical students Rocky Vista University 2012-present Instructor, Human Behavior, Core Curriculum for second year Medical Students 2005-present Supervisor, third year medical students on Psychiatry rotation Denver General Hospital 1993-1995 and 2004-present Psychiatry Instructor, Kaplan Medical, Exam Prep Step 3 USMLE 2010-2012 Supervisor of Physician Assistant Training Program for Psychiatry Clerkship 2005-2010 Mock Board Examiner, Denver Health Medical Center, Department of Psychiatry 2004-2010 Clinical Faculty Supervisor, second year and fourth year Psychiatry residents 1995-1998 Supervisor, third year Psychiatry residents in Psychiatric Emergency Room and C/L Service 1994-1995 Lecturer, Core Lecture Series in Psychiatry for third year Medical Students 1994-1995 Instructor, Clinical Correlations Course for first year Medical Students 1994-1995 Instructor, Patient Interviewing Course for first year Medical Students 1993-1994 6
HONORS and AWARDS: Fellow, American Psychiatric Association 2015 Shore Award, Department of Psychiatry University of Colorado Health Sciences Center 2006 Chief Resident, Department of Psychiatry University of Colorado Health Sciences Center 1994-1995 Laughlin Fellow Award, Department of Psychiatry University of Colorado Health Sciences Center 1995 Phi Beta Kappa 1984 PUBLICATIONS: Gault, J., Weiss, D., et. al. "Elevated DISCI Transcript Levels in PBMCs during acute psychosis in patients with schizophrenia," Translational Biomedicine, Vol.2 No.1 :4, 2011. Boyer, J., Weiss, D.: "Diagnosis and Management of Conversion Disorder," Current Psychiatry, Submitted October, 2007. Gault, J., Olincy, A., Recksiek, P., Sullivan, B., Hollis, J., Ceilley, J., Helfrich, R., Ritvo, J., Weis, E., Weiss, D., Freedman, R., House, R.,: "Gene Expression Biomarkers of Psychosis," International Congress on Schizophrenia Research, Abstract submitted September, 2006. Stromberg, S., Weiss, D.: "Depression and Quality of Life Issues in Patients with Amyotrophic Lateral Sclerosis," Current Treatment Options in Neurology, September, 2006. Weiss, D., House, R., Dyrl, J.: "Psychiatric Manifestations of Autoimmune Disorders," Current Treatment Options in Neurology, September, 2005. Weiss, D., House, R., Beresford, T.: "Non-Compliance in the Neurological Patient," Current Treatment Options in Neurology, September, 2005 SCIENTIFIC PRESENTATIONS: "Psychopharmacology: An Update for Clinical Practice," Iowa Osteopathic Medical Association, May 1, 2014 "Anxiety Disorders," Rocky Vista University, April, 2013, April 2014 "Depressive Disorders," Rocky Vista University, April, 2013, April 2014 "Fundamentals of Psychiatry," Rocky Vista University, April, 2013, April 2014 7
SCIENTIFIC PRESENTATIONS (continued): "Anxiety Disorders and Effective Treatment Strategies," Denver Health Medical Center, Department of Social Work, October, 2009 "Schizophrenia: An Overview," Denver Health Medical Center, Department of Social Work, September, 2009 "Depression and Effective Treatment Strategies," Denver Health Medical Center, Department of Social Work, August, 2009 "Self Inflicted Gunshot Wounds to the Face: Challenges for the Consulting and Inpatient Psychiatrist," Grand Rounds, University of Colorado Department of Psychiatry, May, 2009 "Antipsychotic Medications," Denver Health Medical Center, Telemedicine Conference, Denver, July, 2007 Channel 2 News, Denver, Living Well Series, "Alzheimer's Disease Caregivers," March, 2000 Channel 2 News, Denver, Living Well Series, "Panic Disorder," September, 1999 Channel 2 News, Denver, Living Well Series, "Stress Management," May, 1999 Statewide DSM-IV Training, Pathmakers of Colorado, Denver, October, 1998 "Assessing Competency in the Acute Care Medical Setting," Vencor Hospital, Denver, April, 1997 "Understanding Depression," Columbine Civitan Club, Englewood, CO, April, 1996 "Substance Abuse in the Psychiatric Patient," School of Pharmacy, University of Colorado, Denver, February, 1996 "Psychiatric Emergencies," United States Army, Medical Detachment Unit 1835 th, 'Aurora, CO, November, 1995 "Somatoform Disorders, Factitious Disorders and Malingering," Asian/Pacific Mental Health Center, Denver, November, 1995 "Anxiety Disorders: Diagnosis and Treatment," CME Lecture, Porter's Hospital Behavioral Health Center, Denver, November, 1995 "Depression: The Diagnosis and Treatment," National Depression Screening Day, Mental Health Association of Denver, October, 1995 8
SCIENTIFIC PRESENTATIONS (continued): Grand Rounds, University of Colorado, Department of Psychiatry, "Difficult Case Conference: CNS Demyelinating Disease Presenting as Mania," April, 1994 Grand Rounds, University of Colorado, Department of Psychiatry, "Difficult Case Conference: Untreated Psychotic Depression." November, 1993. Resident Presentation, Presbyterian/St. Luke's Medical Center, Denver, CO "CT Scan of the Head: An Overview," April, 1992 Jahnigan D., Weiss D.: Study of latrogenic Events Occurring in Hospitalized Patients, Denver Veterans Administration Medical Center, presented at the Western Meeting, Carmel, CA, February, 1987 EXPERT WITNESS TESTIMONY: Herrington vs. Colorado Health Partnerships, LLC November, 2014 Provided expert testimony contributing to successful appeal in denial of payment for psychiatric services leading to change in contracting between Behavioral Health Organizations and providers. 9