Fundamentals of Cancer Prevention
David Alberts Lisa M. Hess Editors Fundamentals of Cancer Prevention Third Edition
Editors David Alberts College of Medicine Arizona Cancer Center University of Arizona Tucson, Arizona USA Lisa M. Hess Department of Obstetrics and Gynecology Indiana University Schools of Medicine and Public Health Indianapolis, Arizona USA ISBN 978-3-642-38982-5 ISBN 978-3-642-38983-2 (ebook) DOI 10.1007/978-3-642-38983-2 Springer Heidelberg New York Dordrecht London Library of Congress Control Number: 2013956353 Springer-Verlag Berlin Heidelberg 2014 This work is subject to copyright. All rights are reserved by the Publisher, whether the whole or part of the material is concerned, specifically the rights of translation, reprinting, reuse of illustrations, recitation, broadcasting, reproduction on microfilms or in any other physical way, and transmission or information storage and retrieval, electronic adaptation, computer software, or by similar or dissimilar methodology now known or hereafter developed. Exempted from this legal reservation are brief excerpts in connection with reviews or scholarly analysis or material supplied specifically for the purpose of being entered and executed on a computer system, for exclusive use by the purchaser of the work. Duplication of this publication or parts thereof is permitted only under the provisions of the Copyright Law of the Publisher's location, in its current version, and permission for use must always be obtained from Springer. Permissions for use may be obtained through RightsLink at the Copyright Clearance Center. Violations are liable to prosecution under the respective Copyright Law. The use of general descriptive names, registered names, trademarks, service marks, etc. in this publication does not imply, even in the absence of a specific statement, that such names are exempt from the relevant protective laws and regulations and therefore free for general use. While the advice and information in this book are believed to be true and accurate at the date of publication, neither the authors nor the editors nor the publisher can accept any legal responsibility for any errors or omissions that may be made. The publisher makes no warranty, express or implied, with respect to the material contained herein. Printed on acid-free paper Springer is part of Springer Science+Business Media (www.springer.com)
In my 45 years as a medical oncologist (38 of which were dedicated to building the University of Arizona Cancer Center), I have evolved from a hematologic malignancy specialist to a medical gynecologic oncologist, and fi nally to a clinical and translational cancer preventionist. If we are to stem the terrible tide of cancer in the 21st century, cancer prevention research, training and dissemination must become the dominant theme in our everyday medical lives! I hope that this will be my legacy while I turn to my magnifi cent wife, Heather (the most accomplished cancer preventionist in the Alberts Family), and my remarkable children, Sabrina, Danny, Tim, and Angelle, and amazing grandchildren, Sammy, Sophie, Sydney, Emma and Tate for love and comfort in the twilight of my exciting and fulfi lling medical career. Finally, a very heartfelt thank you to my brilliant Co-Editor, Dr. Lisa Hess, who has been most responsible for the success of Fundamentals of Cancer Prevention! Thank You, Dave
Contents 1 Introduction to Cancer Prevention............................ 1 David S. Alberts and Lisa M. Hess 2 Assessing Human and Economic Benefits of Cancer Prevention..... 15 Stephen Joel Coons and Benjamin M. Craig 3 The Role of Diet, Physical Activity, and Body Composition in Cancer Prevention....................................... 35 Cynthia A. Thomson 4 Innate and Adaptive Immune Responses to Cancer.............. 81 Karen Taraszka Hastings and Matthew P. Rausch 5 Hereditary Risk for Cancer................................. 123 Katherine S. Hunt, Jessica A. Ray, and Joanne M. Jeter 6 Cancer Health Disparities................................... 151 B. Lee Green, Jenna L. Davis, Desiree Rivers, Kyrel L. Buchanan, and Brian M. Rivers 7 Human Categories and Health: The Power of the Concept of Ethnicity............................................... 195 Kathryn Coe and Craig T. Palmer 8 Complementary and Alternative Approaches to Cancer Prevention....................................... 221 Linda K. Larkey, Heather Greenlee, and Lewis E. Mehl-Madrona 9 Telemedicine, Telehealth, and e-health Technologies in Cancer Prevention....................................... 259 Ana Maria Lopez 10 Global Cancer Prevention................................... 279 Janet Okamoto and Scott J. Leischow 11 Sunscreen-Based Skin Protection Against Solar Insult: Molecular Mechanisms and Opportunities..................... 301 Georg T. Wondrak vii
viii Contents 12 Skin Cancer Prevention..................................... 321 Maria Lluria-Prevatt, Sally E. Dickinson, and David S. Alberts 13 Prevention of Colorectal Cancer.............................. 377 Peter Lance and Patricia Thompson 14 Lung Cancer Prevention.................................... 409 Iman Hakim and Linda Garland 15 Breast Cancer Prevention................................... 445 Patricia A. Thompson, Christina M. Laukaitis, and Alison T. Stopeck 16 Prevention of Prostate Cancer............................... 491 Amit M. Algotar, M. Suzanne Stratton, William L. Harryman, and Anne E. Cress 17 Cervical Cancer Prevention................................. 533 Tomas Nuño, Jessamyn Bowling, and Francisco Garcia 18 Ovarian Cancer Prevention................................. 557 Setsuko K. Chambers and Lisa M. Hess 19 Endometrial Cancer Prevention.............................. 593 Mario M. Leitao Jr. and Richard R. Barakat 20 Cancer Survivorship....................................... 613 Steven Plaxe, Robert Krouse, and Noreen M. Aziz Index........................................................ 657