Swiss Medical Network Musculoskeletal Conference Surgical Technique and 30-Year Results of the Periacetabular Osteotomy (PAO)

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Swiss Medical Network Musculoskeletal Conference 2017 Surgical Technique and 30-Year Results of the Periacetabular Osteotomy (PAO) Simon D. Steppacher Department of Orthopedic Surgery, Inselspital, University of Bern

The Problem 1958 1984

Surgical Treatment of Hip Dysplasia before PAO Shelf Salter, Varus Osteotomy

Osteotomies of the pelvis > Shelf arthroplasty > Salter > Pemberton > Triple > Chiari

Osteotomies of the pelvis > Shelf arthroplasty > Salter > Pemberton > Triple > Chiari

Osteotomies of the pelvis > Shelf arthroplasty > Salter > Pemberton > Triple > Chiari

Osteotomies of the pelvis > Shelf arthroplasty > Salter > Pemberton > Triple > Chiari

Osteotomies of the pelvis > Shelf arthroplasty > Salter > Pemberton > Triple > Chiari

Osteotomies of the pelvis > Shelf arthroplasty* > Salter > Pemberton > Triple > Chiari* *Salvage procedures

Surgical Treatment of Hip Dysplasia before PAO Shelf Pain 8 years later PAO

Periacetabular Osteotomy (PAO) > First performed in March 1984 > Inventor Prof. R. Ganz Former Chairman Orthopaedic Department Inselspital > Surgical advantages > Long-lasting experience of >30 years

Periacetabular Osteotomy (PAO)

Advantages of the PAO > Large correction potential No soft-tissue restraints (sacrospinous ligaments) > Posterior column remains intact Intact continuity of pelvic ring Early partial weightbearing > True shape remains unchanged Normal childbirth Flückiger et al, Orthopäde, 2000

Surgical Technique > Patient positioning Supine Radiolucent table Freely draped leg

Surgical Technique > Modified Smith-Petersen approach: Ilioinguinal skin incision (Bikini incision)

Surgical Technique > Modified Smith-Petersen approach: Ilioinguinal skin incision (Bikini incision) Lateral cutaneus femoral nerve crossing

Surgical Technique > Approaching the joint: Detachment of inguinal ligament and sartorius muscle

Surgical Technique > Approaching the joint: Detachment of inguinal ligament and sartorius muscle Detachment of abdominal muscles and iliacus muscle (first ilioinguinal window)

Surgical Technique > Approaching the joint: Detachment of inguinal ligament and sartorius muscle Detachment of abdominal muscles and iliacus muscle (first ilioinguinal window) Origin of recuts muscle preserved

Surgical Technique > Performing osteotomies: Ischial osteotomy Spare ischial nerve Optional use of fluoroscopy Incomplete osteotomy

Surgical Technique > Performing osteotomies: Ischial osteotomy Pubic osteotomy Protect neurovascular bundle Medial to eminentia iliopectinea

Surgical Technique > Performing osteotomies: Ischial osteotomy Pubic osteotomy Supra- and retroacetabular osteotomies

Surgical Technique > Mobilizing the acetabular fragment

Surgical Technique > Intraoperative pelvic radiograph to verify correction

Surgical Technique > Fixation in optimized orientation of the fragment with three 3.5 cortical screws

30-Year Results of PAO 100 Survival Rate (%) 75 50 25 10-year: 88% (80% 95%) 20-year: 61% (49% 72%) Endpoints: - Conversion to THA - Progression of OA - Insufficient clinical result 0 0 30-year: 29% (17% 42%) 5 10 15 20 25 30 Steppacher et al, CORR, 2008 Lerch et al, CORR, 2017 Followup (years)

Results: Predictive factors for failure Category Parameter Hazard Ratio p-value Demographic Age at operation > 40 years 4.32 p<0.001 Clinical Preoperative Merle d Aubigné Postel score < 14 6.33 p<0.001 Preoperative limp 1.67 p=0.001 Preoperative pain in flexion/internal rotation 3.63 p<0.001 Preoperative pain in extension/external rotation 2.47 p=0.021 Preoperative internal rotation <20 4.29 p<0.001 Radiographic Preoperative OA Tönnis > grade 1 4.98 p<0.001

Results: Predictive factors for failure Category Parameter Hazard Ratio p-value Demographic Age at operation > 40 years 4.32 p<0.001 Clinical Preoperative Merle d Aubigné Postel score < 14 6.33 p<0.001 Preoperative limp 1.67 p=0.001 Preoperative pain in flexion/internal rotation 3.63 p<0.001 Preoperative pain in extension/external rotation 2.47 p=0.021 Preoperative internal rotation <20 4.29 p<0.001 Radiographic Preoperative OA Tönnis > grade 1 4.98 p<0.001

30-Year Results of PAO 100 Survival Rate (%) 75 50 25 Age < 20 Years Age < 30 Years Age > 40 Years Age > 45 Years 0 0 5 10 15 20 25 30 Followup (years)

Results: Predictive factors for failure Category Parameter Hazard Ratio p-value Demographic Age at operation > 40 years 4.32 p<0.001 Clinical Preoperative Merle d Aubigné Postel score < 14 6.33 p<0.001 Preoperative limp 1.67 p=0.001 Preoperative pain in flexion/internal rotation 3.63 p<0.001 Preoperative pain in extension/external rotation 2.47 p=0.021 Preoperative internal rotation <20 4.29 p<0.001 Radiographic Preoperative OA Tönnis > grade 1 4.98 p<0.001

Results: Predictive factors for failure Category Parameter Hazard Ratio p-value Demographic Age at operation > 40 years 4.32 p<0.001 Clinical Preoperative Merle d Aubigné Postel score < 14 6.33 p<0.001 Preoperative limp 1.67 p=0.001 Preoperative pain in flexion/internal rotation 3.63 p<0.001 Preoperative pain in extension/external rotation 2.47 p=0.021 Preoperative internal rotation <20 4.29 p<0.001 Radiographic Preoperative OA Tönnis > grade 1 4.98 p<0.001

30-Year Results of PAO 100 Survival Rate (%) 75 50 25 OA = 0 OA = 1 OA > 2 0 0 5 10 15 20 25 30 Followup (years)

10-year followup

10-year followup 20-year followup

10-year followup

Impingement following PAO

30-Year Results of PAO 100 Survival Rate (%) 80 60 40 20 Optimal orientation of acetabulum and offset Suboptimal orientation and offset 0 0 2 4 6 8 10 Followup (years) Albers et al, CORR, 2013

Hip Dysplasia Acetabular Retroversion

Treatment Options in Acetabular Retroversion Anteverting PAO Surgical Hip Dislocation

PAO for Acetabular Retroversion 100 Survival Rate (%) 80 60 40 p = 0.0002 Anteverting PAO Surgical hip dislocation with acetabular trimming 20 Zurmühle et al, CORR, 2017 0 0 2 4 6 8 10 12 14 16 Followup (years)

Size of the Acetabulum Dysplasia Retroversion Deep Hip Protrusio posterior anterior lateral medial Steppacher et al, Osteoarthritis Cartilage, 2014

Conclusion > The periacetabular osteotomy (PAO) Gold standard >30 years of experience > Key factors for a good long term result are Correct reorientation of the acetabular fragment Treatment of impingement if present Joint with no or only little degeneration

February 1 3, 2018