Day-at-a-Glance. Saturday, June 2, 2018

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Saturday, June 2, 2018 1:00 pm 5:30 pm Pre-Meeting Symposia (Additional Fee) Advanced Immunology Basic Science for the Clinician The Immunology of Kidney Transplantation Transplant Center QAPI and Advanced Leadership: Navigating the Complex Regulatory Waters The Art and Science of Transplantation: Assessment and Care of a Complex Patient Population (In Collaboration with NATCO / ITNS) Managing and Mitigating Transplant Infections Reaching Across the Diaphragm: Dilemmas Posed by Combined Heart and Liver Disease (Case-Focused Discussions) Immunobiology of ABMR Bench to Bedside 3:00 pm 4:00 pm Coffee Break Level 6 Foyer 5:30 pm 7:30 pm Opening Reception with Exhibits 5:30 pm 7:30 pm Poster Reception A in Exhibit Hall (Presenters in Attendance)

Sunday, June 3, 2018 7:00 am 8:15 am Sunrise Symposia: Interactive Keep It Going! Long-Term Success After Heart Transplantation Pulmonary Vascular Complications of Liver Disease: Management and Outcomes Pre- and Post-Transplant Virtual Transplant Diagnostic Testing Multidisciplinary Transplant Trainee Hot Topic Debate 7:00 am 8:15 am Sunrise Symposia: Didactic VCA: Where are We Now? Single vs. Dual Kidney Transplantation: 2 for 1 or 1 for 2? Understanding and Optimizing Liver Transplantation Outcomes in the Obese Cirrhotic Patient Frontiers in CMV - Bench to Bedside Decision-Making for the Complicated Diabetic Patient Role of Autophagy in Regulation of Immune Responses New Indications and Approaches in Targeting Tregs Special Considerations in Transplanting the Very Young 8:15 am 8:30 am Break 8:30 am 9:30 am Joint Plenary I 9:30 am 9:45 am Joint Award Session 9:45 am 10:00 am AST Awards

10:00 am 10:15 am AST Lifetime Achievement Award 10:15 am 10:30 am ASTS Awards 10:30 am 10:45 am ASTS Pioneer Award 10:30 am 2:00 pm Exhibit Hall and Poster Session B Viewing Open 10:45 am 11:15 am Coffee Break in Exhibit Hall 11:15 am 12:45 pm Midday Symposia: Interactive C4 Paper 11:15 am 12:45 pm Midday Symposia: Didactic Liver Transplantation for Alcohol Hepatitis Should We Continue Prioritizing Kidney-Heart and Kidney-Liver Transplant Candidates Over Kidney-Alone Candidates? Is It Time to Change the Pediatric Kidney Allocation Paradigm from Expedited Transplantation or to Delay Transplantation to Focus On Better Class II HLA Epitope Matching? Room 611-61 Challenges in Managing Antibody-mediated Allograft Injury To Pump or Not to Pump Quagmires in Donor Heart Allocation Acute and Chronic Antibody Mediated Rejection in Lung Transplant: Alloimmunity and Autoimmunity Top Papers in Transplant Infectious Diseases Bench to Bedside- Costimulatory and Co-Inhibitory Pathways in Transplantation

Epigenetic Regulation of T Cell Responses Emerging Areas in Regulation of Immunity and Immunosuppression VCA: From Head to Finger Update 12:45 pm 1:00 pm Break 1:00 pm 2:15 pm Sponsored Satellite Symposia @ Sheraton Seattle Hotel Sponsored by Sanofi Genzyme Grand Ballroom A/B, Second Floor Sponsored by One Lambda Metropolitan Ballroom A/B, Third Floor 1:00 pm 2:15 pm Luncheon Workshops (Additional Fee) Controversies in BK: A Case-Based Approach Room 205 Care of Allograft Recipients in Transition (CARE - ART) Room 204 Social Media in Organ Donation and Education Room 310 1:30 pm 4:30 pm Transplantation in Depth (Basic) Mechanisms of tissue Fibrosis and How They Apply to Chronic Allograft Injury 2:00 pm 3:45 pm Exhibit Hall and Poster Session B Viewing Closed 2:15 pm 2:30 pm Break 2:30 pm 4:00 pm Concurrent Oral Abstract Sessions Kidney Acute Antibody Mediated Rejection Kidney Deceased Donor Allocation 1 Liver: Immunosuppression and Rejection Liver: Recipient Selection Kidney Immunosuppression: mtori Based Regimens

Kidney Living Donor: Selection Xenotransplantation Antigen Presentation / Allorecognition / Dendritic Cells Kidney Infectious - Viral Hepatitis Islet Cell and Cell Transplantation Room 2AB Kidney: Pediatrics 1 Room 3AB Lung: From Allocation to Outcomes Room 303 Small Bowel: All Topics Room 210 Student Program The Science, The Art, And The Allure of Transplantation 2:30 pm 6:00 pm Multidisciplinary Transplant Professionals Symposium Assessing and Addressing Medication Non-Adherence in the Real World Clinical Setting 2:30 pm 6:00 pm Featured Nursing Symposium (In Collaboration with NATCO / ITNS) Innovation in Transplantation: Leadership and Education Health Literacy 3:45 pm 7:00 pm Exhibit Hall and Poster Session B Viewing Open 4:00 pm 4:30 pm Coffee Break in Exhibit Hall 4:30 pm 6:00 pm Concurrent Oral Abstract Sessions Kidney Complications: Disease Recurrence

Kidney Donor Selection / Management Issues 1 Liver - Kidney Issues in Liver Transplantation Kidney Immunosuppression: Co-stimulation Based Regimens Acute Rejection Novel Therapeutics Kidney Transplant Goes Viral The Guest That NEVER Leaves: Immunologic Challenges in Heart Transplantation Non-Organ Specific: Disparities to Outcome and Access to Healthcare Kidney Cardiovascular and Metabolic 1 Room 303 Kidney Psychosocial 1 Room 210 5:45 pm 7:00 pm ASTS Town Hall & Reception Room 400 6:00 pm 7:00 pm Poster Reception B in Exhibit Hall (Presenters in Attendance)

Monday, June 4, 2018 7:00 am 8:15 am Sunrise Symposia: Interactive Debates in Heart Transplantation The Art of a Successful Lung Transplant Challenges in ICU Management of Critically Ill Patients with ESLD How to Effectively Use the Good Livers with Bad Stories Should I Accept this Donor? When to call your ID Friends at 2 AM - A Case-Based Panel Non-Directed Living Donors - A Debate Clinical Practice, Teaching, AND Research Oh My! Tools to Ease the Transition to a New Pharmacist Position I Get by with a Little Help from My Friends: Multispecialty Evaluation of the Pediatric Solid Organ Transplant Candidate 7:00 am 8:15 am Sunrise Symposia: Didactic Unconventional Pathways in Transplant Rejection Variability of Organ Utilization by DSA: Analysis of Issues Including OPO Recovery Factors, Transplant Program Behaviors and Regulatory Influences Endemic Infections or Zebras? Perspectives in SOT Impact of Aging on Graft Immunogenicity and Injury 8:15 am 8:30 am Break 8:30 am 9:15 am Joint Plenary II 9:15 am 9:45 am ASTS Presidential Address

9:45 am 10:15 am AST Presidential Address 10:15 am 10:45 am State-of-the-Art Presentation VCA: Past, Present, and Future Jean-Michel Dubernard, MD, PhD 10:30 am 2:00 pm Exhibit Hall and Poster Session C Viewing Open 10:45 am 11:15 am Coffee Break in Exhibit Hall 11:15 am 12:45 pm Midday Symposia: Didactic Complicated Complications Complicate the Use of Mechanical Circulatory Support Living Donor Liver Transplant: Inflow, Outflow, How Low Can We Go Liver Transplantation in Challenging Cases: A Bridge too Far? Viral Infections: State-of-the-Art Prevention Hall B Bench to Bedside- Overcoming Sensitization and Donor Antibodies New Updates on T Cell Dysfunction/Exhaustion Emerging Role of Nanotechnology in Transplantation KPD Innovation Program Quality Assessment Medication Management through Transplanted Women's Life Stages Liver Transplantation for Metabolic Disease The Economic Consequence of our Actions and Inactions

12:45 pm 1:00 pm Break 1:00 pm 2:15 pm Sponsored Satellite Symposia @ Sheraton Seattle Hotel Sponsored by Shire/Merck Grand Ballroom A/B, Second Floor Sponsored by Novartis Metropolitan Ballroom A/B, Third Floor Sponsored by Transplant Genomics Grand Ballroom D, Third Floor Luncheon Workshops (Additional Fee) Optimized Islet Isolation Techniques for Improving Outcomes of Islet Auto-Transplantation Room 205 Prevention and Management of Long-term Viral Infections Room 310 Looking Under the Hood of High Impact Research: From Idea to AJT Publication Room 204 2:00 pm 3:45 pm Exhibit Hall and Poster Session C Viewing Closed 2:15 pm 2:30 pm Break 2:30 pm 4:00 pm Concurrent Oral Abstract Sessions Kidney Chronic Antibody Mediated Rejection Kidney Living Donation: Donor and Recipient Outcomes Ischemia Reperfusion Injury: Time to Change the Paradigm? Kidney Immunosuppression: Induction Therapy Liver Retransplantation and Other Complications Liver: Viral Hepatitis Novel Regulatory Pathways in Tolerance CMV: Bench to Bedside

B-cell / Antibody IRI Acute Injury: Basic Location, Location, Allocation in Heart Transplantation PTLD / Malignancies: All Topics Kidney: Pediatrics 2 Room 3AB Surgical Issues (Open, Minimally Invasive): All Organs Room 2AB VCA Room 303 Kidney Psychosocial 2 Room 210 2:30 pm 6:00 pm Multidisciplinary Transplant Professionals Symposium The Legal and Pseudo-Legal: Navigating Substance Use and Abuse in Transplantation 3:45 pm 7:00 pm Exhibit Hall and Poster Session C Viewing Open 4:00 pm 4:30 pm Coffee Break in Exhibit Hall 4:30 pm 6:00 pm Concurrent Oral Abstract Sessions Kidney Immunosuppression: Desensitization Kidney Complications: Late Graft Failure Liver: MELD, Allocation and Donor Issues 1 Kidney Complications: Diagnostic Considerations Kidney Living Donor: Long Term Outcomes

Addressing Re-Emerging Infectious Challenges to Transplantation Strategies to Promote Transplant Tolerance Liver: Pediatrics Endothelial Cell Biology Innate Immunity: Chemokines, Cytokines, Complement Pancreas and Islet 1 Non-Organ Specific: Economics, Public Policy, Allocation, Ethics 1 Kidney: Cardiovascular and Metabolic 2 Room 303 Psychosocial and Treatment Adherence Room 3AB Regulatory Issues Room 2AB Kidney: Surgical Consideration Room 210 5:45 pm 7:00 pm AST Town Hall & Reception Room 400 6:00 pm 7:00 pm Poster Reception C in Exhibit Hall (Presenters in Attendance)

Tuesday, June 5, 2018 7:00 am 8:15 am Sunrise Symposia: Interactive Expanding the Indications for Liver Transplantation The Right Choice for the Diabetic with ESRD Strategies to Ensure Transplant-Readiness : Preparing Patients for Post- Transplant Life in the Pre-Transplant Setting 7:00 am 8:15 am Sunrise Symposia: Didactic Management of the Kidney Waitlist Antibiotic Use, Drug Resistance and Stewardship in Solid Oran Transplant Recipients Understanding Chronic AMR in Liver Transplants Tissue Engineering and Xenotransplantation More than X or Y: Impact of Gender and Sex in Transplantation The Challenges for Adolescent and Young Adult Liver Transplant Candidates and Recipients It s More Than Just Transition! Why Is My Patient Sick? Tell Me Quick! Emerging Perfusion Technology: Challenges to Implementation Achieving Health Equity in Transplantation 8:15 am 8:30 am Break 8:30 am 9:30 am Joint Plenary III 9:30 am 10:00 am State-of-the-Art Presentation Systems Immunology in Health and Disease

Mark M. Davis, PhD 10:00 am 10:45 am Controversies in Transplantation - Basic Is the Microbiome Really Important in Transplantation? 10:00 am 10:45 am Controversies in Transplantation - Clinical Weeding out Fact from Fiction in Substance Abuse: How Much is Too Much for Transplantation or Donation? 10:30 am 2:00 pm Exhibit Hall and Poster Session D Viewing Open 10:45 am 11:15 am Coffee Break in Exhibit Hall 11:15 am 12:45 pm Midday Symposia: Interactive Reproductive Health in Solid Organ Transplantation 11:15 am 12:45 pm Midday Symposia: Didactic Damn the Torpedoes: Donors with HIV, HCV, and HBV New Aspects of Immune Memory The Science of Decision Making in Organ Allocation Well, Isn t that Special: Immunosuppression Management in Special Populations Efforts to Reduce Organ Discards Summary of the NKF s Consensus Conference Liver Transplantation Versus Simultaneous Liver Kidney Transplantation: Choosing The Road Less Traveled The Transplant Therapeutics Consortium: Progress in Bringing New Therapies to Patients Bench to Bedside - Overcoming Complement in Transplant Rejection

Broader Sharing in Liver Transplantation: Current Proposals for Allocation and Metrics Pancreas Transplantation: How I Do It? National Academy of Medicine (NAM) report on Donor Intervention Research: Summary and Future Outlook 12:45 pm 1:00 pm Break 1:00 pm 2:15 pm Sponsored Satellite Symposia @ Sheraton Seattle Hotel Sponsored by Novartis Grand Ballroom A/B, Second Floor Sponsored by CareDx Metropolitan Ballroom A/B, Third Floor 1:00 pm 2:15 pm Luncheon Workshops (Additional Fee) Getting your Patients Out the Door Challenges and Opportunities in the Medication Discharge Process Room 204 Transplant Dermatology: It's a New Frontier So Get on Board Room 205 mhealth in Transplant: The Path from Potential to Reality Room 210 2:00 pm 3:45 pm Exhibit Hall and Poster Session D Viewing Closed 2:15 pm 2:30 pm Break 2:30 pm 4:00 pm Concurrent Oral Abstract Sessions Kidney Paired Exchange Kidney Deceased Donor Allocation 2 Liver: MELD, Allocation and Donor Issues 2 Kidney Immunosuppression: General Considerations 1 Kidney: Acute Cellular Rejection Biomarkers, Immune Monitoring and Outcomes: Basic

Chronic Graft Injury Kidney Infectious - Pot-Pourri T Cell Biology Pancreas and Islet 2 Non-Organ Specific: Economics, Public Policy, Allocation, Ethics 2 Donor Management: All Organs Excluding Kidney Room 3AB Kidney: Polyoma Room 2AB 2:30 pm 6:00 pm Multidisciplinary Transplant Professionals Symposium Transplantation in Older Adults 2:30 pm 6:00 pm Pediatric Symposium Tolerance in Children and Improving Graft Longevity in Pediatric Transplantation 3:45 pm 7:00 pm Exhibit Hall and Poster Session D Viewing Open 4:00 pm 4:30 pm Coffee Break in Exhibit Hall 4:30 pm 6:00 pm Concurrent Oral Abstract Sessions Kidney Complications: Antibody & Late Outcomes Kidney Donor Selection / Management Issues 2 Kidney Living Donation: Programmatic Issues Liver: Hepatocellular Carcinoma and Other Malignancies

Kidney Immunosuppression: General Considerations 2 Biomarkers, Immune Monitoring and Outcomes: Clinical Stem Cell, Cellular Therapies and Regenerative Medicine Liver: Living Donors and Partial Grafts New Approaches to Target Regulatory T Cells New Frontiers in HIV and Hepatitis Non-Organ Specific: Economics, Public Policy, Allocation, Ethics 3 Late Breaking Room 3AB Quality Assurance Process Improvement Room 2AB Kidney: Perioperative Considerations Room 303 Tolerance: Clinical Studies Room 210 6:00 pm 7:00 pm Poster Reception D in Exhibit Hall (Presenters in Attendance) 7:30 pm 10:30 pm ATC Night Out (Additional Fee) Museum of Flight - Offsite

Wednesday, June 6, 2018 7:00 am 8:15 am Sunrise Symposia: Interactive Marijuana Use in Waitlist Candidates: True Risks and Operationalizing Risk Management Presumed Consent 7:00 am 8:15 am Sunrise Symposia: Didactic Ethical and Unique Issues for Women in Solid Organ Transplant Too Sick for Liver Transplant: Practical Strategies to Manage a Cirrhotic Patient at the End-of-Life Failure to Launch: Navigating Medication Access in the Ambulatory Setting Psychosocial Challenges in Pediatric Kidney Transplantation - Case Presentations Transplant Surgery Education and Accreditation: Our Generation and the Next Generation Room 608-620 Difficult Cases in Intestinal Transplantation - An Open Discussion Amongst Major Centers The Role of the Microbiome and in Transplant Outcomes Biomarkers of Clinical Transplant Tolerance Living Donor Follow-up: Improving Patient Engagement and Outcomes Emerging Areas of Transplantation: Opportunities for Basic Science 8:15 am 8:30 am Break 8:30 am 10:00 am Joint Plenary IV

10:00 am 10:15 am Coffee Break Atrium Lobby Foyer 10:15 am 11:30 am What s Hot; What s New (Basic, Translational, Clinical)