Transrectal ultrasound scan & prostate biopsies (TRUS)

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Transrectal ultrasound scan & prostate biopsies (TRUS) Exceptional healthcare, personally delivered

Why do I need this procedure? This procedure is performed primarily to check for prostate cancer. Your doctor will likely have recommended this if you have a raised prostate specific antigen (PSA), or an abnormalfeeling prostate gland. What does the procedure involve? Biopsy samples are taken from your prostate gland, using a transrectal (within the bottom) ultrasound scanning probe. Are there any alternatives? Prostate biopsies are the most reliable way to check for prostate cancer. Other options include: 1. PSA monitoring, and deferring biopsies until the PSA rises 2. MRI scanning the prostate may detect early high-grade cancers, but can fail to detect low-grade cancer 3. Trans-perineal prostate biopsies, performed under general anaesthetic, are taken through the perineal skin (between the scrotum and anus). What happens before the procedure? You will be provided with antibiotic tablets. It is important to take these as directed, usually starting the course two hours before the procedure. Please let us know if you are taking any blood-thinning medication (e.g. clopidogrel, aspirin, warfarin, dabigatran, rivaroxaban, apixaban). We will usually have asked you to hold these prior to the procedure. 2

Coming in to hospital Your appointment letter will contain full details. We normally request that you come to Gate 36, Level 1, Southmead Hospital. What happens during the procedure? The procedure and its risks will be explained to you by the doctor. We will ask you to remove your trousers and underwear, and lie on your left hand side on a couch. The doctor will examine your prostate gland with a gloved finger, before passing the ultrasound probe into your rectum. Whilst this can be uncomfortable, most men tolerate it well. The doctor will use the scanner to visualise the prostate gland. Local anaesthetic is injected around the prostate gland, under ultrasound guidance. The device we use to take the biopsies makes a loud clicking noise. Normally 10-18 samples are taken. (From: The Prostate small gland, big problem by Roger S Kirby, Prostate Research Campaign UK, 2000) How long does the procedure take? 10-20 minutes. 3

Are there any risks to the procedure?* n Common Almost all patients will notice blood in their urine, semen, or from the rectum following this procedure. Ensure you increase your fluid intake if you notice blood in your urine, to help flush your bladder through. Whilst generally the procedure is usually well tolerated, discomfort is common (10-50%). Take simple analgesia (e.g. paracetamol, ibuprofen (if not allergic/intolerant)) until the discomfort settles. noccasional We give antibiotics pre procedure to reduce the risk of infection; however, there is a still risk of an infection. Where serious, this can lead to sepsis (infection within the bloodstream, requiring hospital admission and IV antibiotics, occurring in about 2% of patients). If you feel unwell following the biopsy test, with fevers, shivers, shakes, it is essential you contact your doctor or come to the Emergency Department. Due to bruising, there is a temporary risk of erectile dysfunction (5%) Some men have urinary retention (difficulty passing urine) following the test, and this may require a catheter (2%). Pass urine before going home following the test and tell a member of staff if you are struggling. Small foci of cancer may be missed by the biopsies (2-10%). We will continue to monitor your PSA following the biopsies, and review your MRI scan. Further tests may be required if there is any ongoing concern. 4

n Rare There may be a need for repeat procedure (0.4-2%), if the biopsy samples are inconclusive. What happens following the procedure? You will be free to leave, after you have passed urine. We will provide you with a copy of you discharge letter, which also gets sent to your GP. You will be contacted with the biopsy results after they have been reviewed by our multi-disciplinary team. This can take 2-3 weeks. Seeing blood in your urine/semen or via the rectum is very common (see Side Effects). Ensure you increase your fluid intake if you notice blood in the urine. Blood in the semen can persist for a few weeks. If you feel unwell (fevers, shivers nausea), contact the urology department/your GP/attend the emergency department. Can I drive home following the procedure? Whilst driving following the procedure is allowed, it is your responsibility to ensure you are fit and safe to drive. You may wish for a friend/relative to drive you home in the event of any discomfort following the procedure. 5

Further information *British Association of Urological Surgeons www.baus.org.uk Southmead Hospital urology department 0117 4145000 Southmead Hospital urology cancer specialist nurses 0117 4140512 Prostate Cancer UK prostatecanceruk.org 0800 074 8383 Macmillan Cancer Support www.macmillan.org.uk 0808 808 00 00 6

How to contact us: Southmead Hospital Urology Department 0117 4145000 Southmead Hospital Urology cancer specialist nurses 0117 4140512 www.nbt.nhs.uk/urology If you or the individual you are caring for need support reading this leaflet please ask a member of staff for advice. North Bristol NHS Trust. This edition published June 2017. Review due June 2019. NBT002040