Partitioning of Growth of Pigs into Protein and Lipid

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Partitioning of Growth of Pigs into Protein and Lipid L. R. S. NOV 9, 2015 L. R. S. Partitioning of Growth of Pigs into Protein and Lipid NOV 9, 2015 1 / 27

Otherwise Known As what retired faculty do. L. R. S. Partitioning of Growth of Pigs into Protein and Lipid NOV 9, 2015 2 / 27

Background Indiana, corn, pigs Purdue, Cornell, Guelph Mixed models since 1950 Random regression models, 1994, 4th order Legendre polynomials Statistical models/animal Breeding L. R. S. Partitioning of Growth of Pigs into Protein and Lipid NOV 9, 2015 3 / 27

1970 Ithaca L. R. S. Partitioning of Growth of Pigs into Protein and Lipid NOV 9, 2015 4 / 27

Henderson MSc in Nutrition, 1935, Iowa St PhD in Animal Breeding, started in 1946 Hired as Associate Prof at Cornell, 1948 Full Professor in 1951. National Academy of Sciences (9 others) L. R. S. Partitioning of Growth of Pigs into Protein and Lipid NOV 9, 2015 5 / 27

Since Retirement History of Genetic Evaluation Methods in Dairy Cattle SAC for Genome Canada project on PRRS in swine Invited paper to WCGALP in Vancouver (on PRRS) Fiction novel (The Ferrari Affair) Meat and dairy sheep genetic evaluations (CEPOQ) Project in Atlantic salmon (sea lice) - genomics ELARES open journal, free, instant L. R. S. Partitioning of Growth of Pigs into Protein and Lipid NOV 9, 2015 6 / 27

Intro Knowing the protein and lipid deposition rates of individual pigs would allow changing the feed ingredients during the course of the test station growth period, and thereby save money and keep pigs from getting too fat. L. R. S. Partitioning of Growth of Pigs into Protein and Lipid NOV 9, 2015 7 / 27

Test Periods 60 to 200 days of age Up to 120 kg BWT (or 140 kg) 3 and more weights (7 would be better) Daily feed intake, visits to feeders, duration at feeder. 1-3 backfat scans, towards the end. L. R. S. Partitioning of Growth of Pigs into Protein and Lipid NOV 9, 2015 8 / 27

References Bridges, T. C., Turner, L. W., Smith, E. M., Stahly, T. S., Loewer, O. J. 1986. A mathematical procedure for estimating animal growth and body composition. Trans. ASAE 29:1342. Doeschl-Wilson, A. B., Knap, P. W., Kinghorn, B. P., Van der Steen, H. A. M. 2007. Using mechanistic animal growth models to estimate genetic parameters of biological traits. Animal:1:489=499. Knap, P. W., Roehe, R., Kolstad, K., Pomar, C., Luiting, P. 2003. Characterization of pig genotypes for growth modeling. J. Anim. Sci. 81:E187-E195. NRC 2012. Models for Estimating Nutrient Requirements of Pigs. Eleventh Revised Edition. L. R. S. Partitioning of Growth of Pigs into Protein and Lipid NOV 9, 2015 9 / 27

Refs Schinkel, A. P., de Lange, C. F. M. 1996. Characterization of growth parameters needed as inputs for pig growth models. J. Anim. Sci. 74:2021-2036. Schinkel, A. P., Einstein, M. E., Jungst, S., Booher, C., Newman, S. 2009. Evaluation of different mixed model nonlinear functions to describe the body weight growth of pigs of different sire and dam lines. The Professional Scientist 25:307-324. Schaeffer, L. R., de Lange, C. F. M. 2013. Method to partition growth of pigs on test into protein and lipid contributions. Elares:52. L. R. S. Partitioning of Growth of Pigs into Protein and Lipid NOV 9, 2015 10 / 27

Data 20,636 pigs with FI data and with pedigree info. Three breeds (YO, LA, DU). 2004 to 2012. Birth, start of test, end of test - minimum wts. Feed Intake: 14 consecutive days or more. L. R. S. Partitioning of Growth of Pigs into Protein and Lipid NOV 9, 2015 11 / 27

Procedure 1 Estimate daily body weights for each day 2 Estimate accumulated feed intake curve by day 3 Estimate daily protein and lipid deposition L. R. S. Partitioning of Growth of Pigs into Protein and Lipid NOV 9, 2015 12 / 27

Daily Body Weights BWT t = 1.5 + A [1.0 exp( exp(b) (t C ))] t = age in days. Birthweight of 1.5 kg assumed, unless known. Weights should be continuously increasing. A, B, and C estimated for each pig, then daily weights calculated over test period. (Differential Evolutionary Algorithms) L. R. S. Partitioning of Growth of Pigs into Protein and Lipid NOV 9, 2015 13 / 27

What are DE Algorithms? Start with a random group of 10 possible solutions. Define your Fitness function. Propose a challenger solution using Mutation and Recombination. If challenger has better Fitness than parent in group of 10, then replace parent. Iterate until group of 10 are identical. L. R. S. Partitioning of Growth of Pigs into Protein and Lipid NOV 9, 2015 14 / 27

Starting Solution Starting solutions for growth curve of a pig. Set A B C Fitness 1 268.5-11.8 1.72-1384. 2 272.3-12.8 2.67-1309. 3 268.7-10.8 1.69-1212. 4 263.6-15.8 2.62-1429. 5 259.8-8.8 1.76-1851. 6 264.9-7.7 1.67-1408. 7 266.1-11.7 1.63-1457. 8 270.4-13.7 1.71-1630. 9 259.1-14.8 2.70-1746. 10 261.0-9.5 1.64-1587. L. R. S. Partitioning of Growth of Pigs into Protein and Lipid NOV 9, 2015 15 / 27

Weight Curve Values Gender A B C Castrated 270.4-10.48923 2.01149 Females 253.6-10.12786 1.93885 L. R. S. Partitioning of Growth of Pigs into Protein and Lipid NOV 9, 2015 16 / 27

Graphs Average Growth Curves Body Weight, kg 0 20 40 60 80 100 120 140 Castrates 120kg Castrates 140kg Females 120kg Females 140kg 0 50 100 150 Age, d L. R. S. Partitioning of Growth of Pigs into Protein and Lipid NOV 9, 2015 17 / 27

Accumulated Feed Intake Curve acfi t = b 0 + b 1 BWT t + b 2 (BWT t ) 2 BWT = WT /(MaxWT ) to give numbers from 0 to 1. acfi scaled to make all of them a positive number. Simple linear regression. Gender b 0 b 1 b 2 Castrated -49.78 213.34 141.26 Females -50.74 223.17 121.51 L. R. S. Partitioning of Growth of Pigs into Protein and Lipid NOV 9, 2015 18 / 27

ACFI Curve Average Feed Intake Curve Feed Intake, kg 0 50 100 150 200 250 300 20 40 60 80 100 120 140 Body Weight, kg L. R. S. Partitioning of Growth of Pigs into Protein and Lipid NOV 9, 2015 19 / 27

Total Protein and Lipids TL t = c 0 + c 1 acfi t TP t = d 0 + d 1 BWT t and NRC formulas are 100% correct L. R. S. Partitioning of Growth of Pigs into Protein and Lipid NOV 9, 2015 20 / 27

DE Procedure I 1. Starting values for c 0, c 1, d 0, d 1. 2. Calculate TL and TP for all days on test. 3. Convert to daily lipid and protein values. 4. Determine PDmax. 5. Water content, h2o = 4.322 + 0.0044 PDmax 6. Empty body weight ebw 1 t = BWT t 0.3043 (BWT t ) 0.6 and ebw 2 t = (1.189 TP t + TL t ) + h2o (TP t ) 0.855 L. R. S. Partitioning of Growth of Pigs into Protein and Lipid NOV 9, 2015 21 / 27

DE Procedure II 7. and err t = ebw 1 t ebw 2 t cfit = cfit (err t ) 2 over all t. 8. Metabolizable energy intake, (total end of test) 9. Maintenance energy is 10. Difference is MEi = 3250 (DFI ) t MEm = NRG (BWT ) 0.6 t (MEi MEm) = 12.5 (TL end TL 60 )+10.6 (TP end TP 60 ). L. R. S. Partitioning of Growth of Pigs into Protein and Lipid NOV 9, 2015 22 / 27

DE Procedure III 11. NRG, energy requirement of pig is NRG = (MEi 12.5 (TL end TL 60 ) 10.6 (TP end TP 60 ( (BWT ) 0.6 ) 12. Lipid to Protein Ratio 13. Predicted backfat LPR = TL end TP end pbf = 5.0 + 12.3 LPR + 0.13 TP 14. Difference between pbf and actual BF minimized too. L. R. S. Partitioning of Growth of Pigs into Protein and Lipid NOV 9, 2015 23 / 27

Protein, Lipid Functions Gender c 0 c 1 d 0 d 1 Castrated 0.773 0.126 0.561 0.150 Females 0.655 0.117 0.377 0.158 L. R. S. Partitioning of Growth of Pigs into Protein and Lipid NOV 9, 2015 24 / 27

Example Animal 8400 156.39 80.05 127.5 172.46 18.2 Protein(blue), Lipid(red) g/d 0 100 200 300 400 500 600 700 20 40 60 80 100 120 140 Weight, kg L. R. S. Partitioning of Growth of Pigs into Protein and Lipid NOV 9, 2015 25 / 27

Heavy Pigs Project Item Castrated Females End Weight 120kg 140kg 120kg 140kg ADG(60-130d) 1.02 1.02 0.96 0.96 Gain/Feed 0.41 0.41 0.43 0.43 PDmax 174.7 174.7 170.2 170.0 Wt at PDmax 97.3 97.3 93.3 93.3 NRG 198.9 198.4 184.9 184.9 L/P 1.75 1.75 1.51 1.51 P gain 10.8 10.8 10.8 10.7 L gain 22.1 22.2 18.8 18.8 L. R. S. Partitioning of Growth of Pigs into Protein and Lipid NOV 9, 2015 26 / 27

The End Questions, Comments What more can or should be done? www.aps.uoguelph.ca/ lrs/cowsite/ L. R. S. Partitioning of Growth of Pigs into Protein and Lipid NOV 9, 2015 27 / 27