Exercise for Treating Chronic Pain. Christopher Sahler, M.D. December 2 nd, 2014

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Exercise for Treating Chronic Pain Christopher Sahler, M.D. December 2 nd, 2014

Who am I and where did I come from? Born in Rochester, NY Medical School: New York Medical College, Valhalla Physical Medicine and Rehabilitation, Board Certified 2014 Residency at Mount Sinai Hospital, NY Sports Medicine (ABFM), Board Certified 2014 Fellowship at Mount Sinai Hospital, NY

Objectives Brief review of chronic pain Exercise Exercise treatments for chronic pain Prevention of pain Steps to get started

A Quick Word of Caution This lecture is NOT intended to replace individualized medical advice

What is Chronic Pain? Acute pain is normal sensation triggered in the nervous system to alert you to possible injury Chronic pain is often different Pain signals keep firing in the nervous system for weeks, months, even years. There may have been an initial injury or an ongoing cause of pain (ex: arthritis, cancer) But some people suffer chronic pain in the absence of any past injury or evidence of body damage PAINMED.ORG

Chronic Pain is Common Condition Number of Patients in U.S. Reference Chronic Pain 100 million Institute of Medicine Diabetes 25.8 million American Diabetes Assoc. Coronary Heart Disease 16.3 million AHA Cancer 11.9 million American Cancer Society Stroke 7.0 million AHA - Institute of Medicine Report from the Committee on Advancing Pain Research, Care, and Education: Relieving Pain in America, A Blueprint for Transforming Prevention, Care, Education and Research. The National Academies Press, 2011. - Heart Disease and Stroke Statistics 2011 Update: A Report From the American Heart Association. Circulation 2011, 123:e18-e209, page 20.

Where is the pain felt? Location Prevalence Duration >3 months Occurs on >Half Days High Impact on Activities Headache 40% 66% 16% 11% Abdomen 23% 67% 30% 18% Back 39% 81% 45% 32% Neck 31% 81% 47% 32% Shoulder 29% 79% 51% 33% Hand/Wrist 23% 77% 52% 37% Hip/Knee 28% 83% 55% 40% Ankle/Foot 17% 80% 61% 42% http://www.fda.gov/downloads/drugs/newsevents/ucm307835.pdf

Back pain Back pain is a leading cause of disability in Americans More than 26 million Americans experience frequent back pain. Adults with low back pain are often in worse physical and mental health than people who do not have low back pain. Adults reporting low back pain were 3x as likely to be in fair or poor health and >4x as likely to experience serious psychological distress http://www.cdc.gov/nchs/data/hus/hus06.pdf

Pain is expensive U.S. Annual health care costs; $560 billion to $635 billion (in 2010 dollars) Institute of Medicine Report from the Committee on Advancing Pain Research, Care, and Education: Relieving Pain in America, A Blueprint for Transforming Prevention, Care, Education and Research. The National Academies Press, 2011.

Poor sleep An estimated 20% of American adults (42 million people) report that pain or physical discomfort disrupts their sleep a few nights a week or more National Sleep Foundation (http://www.sleepfoundation.org). Sleep in America poll. 2000.

Typical Chronic Pain Treatment Options Rest Topical modalities (heat, ice, TENS, E-Stim) Topical medications Acupuncture Chiropractic care Oral medications (Tylenol, NSAIDs, gabapentin, Opioids) Physical Therapy Injections Surgery

Chronic Pain and Long Term Pain Medication 51% felt they had little or no control over their pain. 60% experience breakthrough pain one or more times daily, severely impacting their quality of life and overall well-being. 59% reported an impact on their overall enjoyment of life. 2006 Voices of Chronic Pain Survey. (American Pain Foundation)

Now what? Hey Doc, I tried everything and still have pain

Goals When Living with Chronic Pain Reduce pain level to manageable levels Curing chronic pain or becoming pain free is often unrealistic in many chronic pain conditions Perform Activities of Daily Living (ADLs) independently with greater easy and comfort Participate in recreational and various activities you enjoy May be different for every person

Exercise and Increased Activity Level What type of exercise or activity? Frequency Duration of each session Duration of total program How do I get started?

Is Exercise Dangerous? There is no conclusive evidence in the medical literature that exercise or activity cause harm and should be avoided in chronic pain conditions

Won t Exercise Make My Pain Worse? INACTIVITY MAKES PAIN WORSE Even in acute back pain, bedrest for any longer than a day or two tends to result in greater pain

Risk Factors for Developing pain In 1999, British researchers studied 2,715 adults without back pain It was not physical activity that increased the risk of low back pain later on but poor health and being overweight

Back pain

Low Back Pain 2011 Italian study for chronic low back pain 261 people 310 patients 12 month physical Normal activity activity program Significantly improved overall health and pain

Low Back Pain Sixty-one randomized controlled trials including 6390 participants: Exercise therapy appears to be effective at decreasing pain and improving function in adults with chronic low-back pain, particularly in healthcare populations. In subacute low-back pain there is some evidence that a graded activity program improves absenteeism outcomes Hayden J, van Tulder MW, Malmivaara A, Koes BW. Exercise therapy for treatment of non-specific low back pain. Cochrane Database of Systematic Reviews 2005, Issue 3.

Return to work In 1992 Swedish researchers randomized 103 low back pain sufferers out of work on disability Exercise program Usual care Returned to work much faster A 2000 study in Finland and a 2005 Swiss study came to similar conclusions 2010 review of 61 studies involving 6,390 people agreed

Chronic/Recurrent Low back pain Back School 19 Randomized control trials which included 3584 patients were included in a review. Authors conclusion: There is moderate evidence suggesting that back schools: Reduce pain Improve function Return-to-work status Compared to exercises, manipulation, myofascial therapy, advice, placebo or waiting list controls Heymans MW, van Tulder MW, Esmail R, Bombardier C, Koes BW. Back schools for non-specific low-back pain.. Cochrane Database of Systematic Reviews 2004, Issue 4.

Back School Educational program teaching practical information: Back care Posture Body mechanics Back exercises (core strengthening, isometric abdominal exercises) Activity programs Prevention techniques Back school works only as well as you make it work by applying your back-care knowledge on a regular basis.

Total Body Resistance Exercise Program - LBP Total Body Resistance Lumbar Extensor Program Control Group Exercise Program Greatest reduction in perceived disability Greatest reduction in pain severity Vincent HK, George SZ, Seay AN, Vincent KR, Hurley RW. Resistance exercise, disability, and pain catastrophizing in obese adults with back pain. Med Sci Sports Exerc. 2014 Sep;46(9):1693-701

Pilates and Low Back pain Decreased pain and increased function with Pilates compared to usual care and physical activity in the short term (<6 months) Pilates is equivalent to other forms of exercise in terms of pain relief Wells C, Kolt GS, Marshall P, Hill B, Bialocerkowski A (2014) The Effectiveness of Pilates Exercise in People with Chronic Low Back Pain: A Systematic Review. PLoS ONE 9(7): e100402.

Iyengar yoga and Low Back Pain Iyengar Yoga Standard Core strengthening and stretching - Better pain reduction - Increased measured Health Related Quality of Life (HRQOL). Nambi GS, Inbasekaran D, Khuman R, Devi S, Shanmugananth, Jagannathan K. Changes in pain intensity and health related quality of life with Iyengar yoga in nonspecific chronic low back pain: A randomized controlled study. Int J Yoga 2014;7:48-53

Preventing Low back pain Review of 13 articles Moderate quality evidence Post-treatment exercises were more effective than no intervention Reducing the rate of recurrences at one year. Two studies demonstrated continue benefit for two years follow-up Conflicting evidence was found for treatment exercise. To me, exercise=good Choi BKL, Verbeek JH, Tam WWS, Jiang JY. Exercises for prevention of recurrences of low-back pain. Cochrane Database of Systematic Reviews 2010, Issue 1

Fibromyalgia Clincal syndrome of diffuse muscular pain: Chronic Non-inflammatory Muscular tender points No true damage to peripheral tissue Associated with headaches, chronic fatigue, irritable bowel syndrome, depression

Fibromyalgia Resistance Training Moderate and moderate to high intensity resistance training improves: Function Pain Tenderness Muscle strength Busch AJ, Webber SC, Richards RS, Bidonde J, Schachter CL, Schafer LA, Danyliw A, Sawant A, Dal Bello-Haas V, Rader T, Overend TJ. Resistance exercise training for fibromyalgia. Cochrane Database of Systematic Reviews 2013, Issue 12

Fibromyalgia Supervised aerobic exercise training has beneficial effects on physical capacity and FMS symptoms. 1 Eight weeks of aerobic exercise was superior to moderate-intensity resistance training for improving pain in women with fibromyalgia. 2 Busch A 1, Schachter CL, Peloso PM, Bombardier C. Exercise for treating fibromyalgia syndrome. Cochrane Database Syst Rev. 2002;(3):CD003786. Busch AJ, Webber SC, Richards RS, Bidonde J, Schachter CL, Schafer LA, Danyliw A, Sawant A, Dal Bello-Haas V, Rader T, Overend TJ. Resistance exercise training for fibromyalgia. Cochrane Database of Systematic Reviews 2013, Issue 12

Fibromyalgia Medications have not been shown to provide any greater benefit than exercise "Aerobic exercise is the most effective weapon we have; healthy people profit from continuous physical exercise, and so do patients with fibromyalgia. Dr. Hauser (European League Against Rheumatism Congress 2014). Nüesch E 1, Häuser W, Bernardy K, Barth J, Jüni P. Comparative efficacy of pharmacological and non-pharmacological interventions in fibromyalgia syndrome: network meta-analysis. Ann Rheum Dis. 2013 Jun;72(6):955-62.

Neck Pain Review of 31 articles There is strong evidence of benefit favoring a multimodal care approach of exercise combined with mobilizations or manipulations for subacute and chronic MND with or with headache in the short and long term. Kay TM, Gross A, Goldsmith CH, Hoving JL, Brønfort G. Exercises for mechanical neck disorders. Cochrane Database of Systematic Reviews 2005, Issue 3

Chronic Knee Pain Osteoarthritis Multiple Studies show increasing quadriceps strength reduces pain and reduces recurrence of knee pain Med Sci Sports Exerc. 2010 Nov;42(11) Effect of quadriceps strength and proprioception on risk for knee osteoarthritis.

Aquatic exercise for the treatment of knee and hip osteoarthritis. Aquatic exercise appears to have some beneficial short-term effects for patients with hip and/or knee OA Low impact Bartels EM, Lund H, Hagen KB, Dagfinrud H, Christensen R, Danneskiold-Samsøe B. Aquatic exercise for the treatment of knee and hip osteoarthritis. Cochrane Database Syst Rev. 2007 Oct 17;(4):CD005523.

Rheumatologic Disease Rheumatoid Arthritis: Inflammatory auto-immune disease Based on the evidence, aerobic capacity training combined with muscle strength training is recommended as routine practice in patients with RA. Tai Chi does not exacerbate symptoms of rheumatoid arthritis. In addition, Tai Chi has statistically significant benefits on lower extremity range of motion Han A, Judd M, Welch V, Wu T, Tugwell P, Wells GA. Tai chi for treating rheumatoid arthritis. Cochrane Database of Systematic Reviews 2004, Issue 3 Hurkmans E, van der Giesen FJ, Vliet Vlieland TPM, Schoones J, Van den Ende ECHM. Dynamic exercise programs (aerobic capacity and/or muscle strength training) in patients with rheumatoid arthritis. Cochrane Database of Systematic Reviews 2009, Issue 4

Prevention Exercise is a great way to prevent chronic pain. The epidemiological evidence is overwhelming

Prevention Starts in Early Years In 1997, Danish researchers tracked 640 school children over 25 years Those who were physically active for at least three hours a week had a lower life-time risk of back pain. Interest in sports and exercise during leisure time is often established in the adolescent period. Continuing physical activity in adulthood may reduce low back problems. Therefore, it seems important to encourage youth to participate in physical activity. Harreby M, Hesselsøe G, Kjer J, Neergaard K. Low back pain and physical exercise in leisure time in 38-year-old men and women: a 25-year prospective cohort study of 640 school children. Eur Spine J. 1997;6(3):181-6.

Prevention In 1998, Finnish researchers studied 498 adults and found that the fittest people had the lowest risk of back problems.

Prevention 2011 study of 46,533 adults, Norwegian researchers found that among young and middle-aged people, the prevalence of chronic pain was 10-12 percent lower for exercisers. The difference was even bigger 21 to 38 percent among women aged 65 or older and, with slightly less dramatic numbers, among older men Landmark T, Romundstad P, Borchgrevink PC, Kaasa S, Dale O. Associations between recreational exercise and chronic pain in the general population: evidence from the HUNT 3 study. Pain. 2011 Oct;152(10):2241-7. doi:

Adherance to Exercise Review of 42 trials with 8243 participants, mainly with osteoarthritis and spinal pain. Interventions such as supervised or individualized exercise therapy and self-management techniques may enhance exercise adherence. Accountability Partner Trainer Set a schedule and stick to it Jordan JL, Holden MA, Mason EEJ, Foster NE. Interventions to improve adherence to exercise for chronic musculoskeletal pain in adults. Cochrane Database of Systematic Reviews 2010, Issue 1.

Does running cause arthritis? A study presented at the annual meeting of the American College of Rheumatology Nov 2014. Recreational running at any ades does not appear to contribute to development of osteoarthritis In fact, it may even be protective in prevent OA. In people who do not have knee OA, there is no reason to restrict participation in habitual running at any time for fear of harming the knee joint Does not apply to people who already have knee OA

Non-pain related benefits Low level of physical activity increases mortality more so than smoking, obesity, hypertension, high cholesterol Active 80 year olds have a lower risk of death than inactive 60 year olds. Reduce mortality and risk of recurrent breast cancer by 50% Lower risk of colon cancer by over 60% Reduce The risk of Alzheimer s disease by 40% Lower risk of stroke, developing diabetes and treating diabetes http://www.exerciseismedicine.org/assets/page_documents/eim%20fact%20sheet%202014.pdf

How Do I Begin?

How Do I Begin? You should have a check up with your primary care physician prior to starting any new exercise routine Mention you are going to be increasing your activity level and starting to exercise Tell them if you have every had any previously problems when exercising Chest pain, Shortness of Breath, Fainting while working out, Family History

How Do I Begin? Start with an activity that you are familiar with and have done in the past If nothing comes to mind, start by going on short walks START SLOW!!

Conclusion Chronic pain is common Exercise and activity are very effective treatments Physical activity is protective in preventing chronic pain No magical single treatment, just start an activity that you enjoy

Remember that inactivity can make pain worse By default, any activity is better than none! The best exercise routine is the one you will actually do

Online Resources Exercise is Medicine www.health.gov/paguidelines www.cdc.gov/physicalactivity/everyone/guide lines/index.html THANK YOU!