COURSE DESCRIPTION COURSE LEA RN ING OBJECTIVES INTENDED AUDIENCE CREDIT

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COURSE DESCRIPTION The course will begin with a discussion of echocardiographic assessment of left and right ventricular function, including presentations on diastolic function and strain imaging for assessing myocardial function. We will then discuss a broad range of disease states for w hich echocardiography is useful, including ischemic heart disease, valvular heart disease, pericardial disease, and cardiomyopathies. The presentations will include basic concepts as well as advanced techniques including 3-D imaging and strain imaging. Throughout the course many cases w ill be presented. U ni que Featur es: Faculty members are clinical sonographers and echocardiologists Easy access to faculty members during the entire conference Afternoon on pediatric/ adult congenital echocardiography Lab accreditation (IAC Echocardiography) Live scanning hands-on Presentations involving multimodality imaging COURSE LEA RN ING OBJECTIVES Upon conclusion of this program, participants should be able to: Apply Doppler principles and hemodynamics to the assessment of valvular heart disease, including systematic assessment of prosthetic valves Use 2-D, Doppler strain methods to assess myocardial function Illustrate the appropriate use of echo Doppler in myocardial and pericardial disease Recognize the utility of echocardiography TEE including 3-D in the interventional practice Integrate the application of echocardiography in heart failure and the treatment Recognize clinical applications of stress echocardiography Attendance at this M ayo course does not indicate nor guarantee competence or proficiency in the performance of any procedures w hich may be discussed or taught in this course. INTENDED AUDIENCE This course is intended for adult cardiologists, cardiac sonographers, cardiology fellow s, surgeons, anesthesiologists, and those w ho have basic experience and know ledge of echocardiography. This course is designed to further advance their experience in clinical application of echocardiography. CREDIT Mayo Clinic College of Medicine is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians. Mayo Clinic College of Medicine designates this live activity for a maximum of 26.25 AMA PRA Category 1 Cr edi t s. Physicians should claim only the credit commensurate with the extent of their participation in the activity. Other H ealth Care Professionals A certificate of attendance w ill be provided to other health care professionals for requesting credits in accordance w ith state nursing boards, specialty societies, or other professional associations. Attendees should ensure in advance that their credentialing or licensing organization accepts AMA PRA Category 1 Credits from the sponsor of this activity.

GRANTS AND EXHIBITS At the time of this printing, a complete listing of commercial supporters (financial or in-kind) w as not available. Appropriate acknowledgment will be given to all supporters at the time of the meeting. Exhibits will be available for viewing at all scheduled breakfast and breaks. DATE AND LOCATION The Basic to A dvanced Echocardiography course will be held M ay 17-20, 2017. Course headquarters will be located at The Omni Grove Park Inn, 290 M acon A venue, A sheville, N C 28804. Phone: 828-252-2711/ Fax: 828-252-7053 All indoor sessions will be held on the 10 th floor of the hotel. General Session: H eritage A & B, Sammons Wing, 10 th Floor Exhibits/Breaks/Breakfast: H eritage Ballroom Foyer, Sammons Wing, 10 th Floor Reception: Skyline Room, Mountainview Terrace, Sammons Wing, 8 th Floor REGISTRA TION Registration is available online. The registration fee includes tuition, comprehensive course syllabus, continental breakfasts, break refreshments, lunch, and welcome reception. Although it is not Department of Cardiovascular Medicine (CV CME) policy to limit the number of registrants for a course, conference room facilities may necessitate closing of enrollment; therefore, early registration is advised. A letter of confirmation will be sent upon receipt of payment and completed registration form on-line. Please present the confirmation letter when checking in at the meeting registration desk. For additional information, contact: Mayo Clinic Cardiovascular Diseases 200 1 st Str eet SW/ GO6-138 Rochester, M N 55905 Website E-mail: cvcme@mayo.edu Phone: 800-283-6296 or 507-266-6703 TRA VEL/ A IRPORT Asheville Regional Airport (AVL) is the recommended airport for arrival. Taxi or rental car is recommended mode of transportation from the airport. The hotel is located approximately 20 minutes from the airport. Driving directions from the airport: Take I-240 into Asheville. Take Exit 5B/ Charlotte Street From I-240 East, turn left on Charlotte Street From I-240 West, turn right on Charlotte Street. Proceed north on Charlotte Street for approximately 0.7 miles. Turn right on Macon Avenue and continue for 0.8 miles. The Omni Grove Park Inn entrance w ill be on your left. Travel arrangements are the sole responsibility of the individual registrant.

LODGING ACCOMMODATIONS N estled in the Blue Ridge M ountains, just beyond Asheville downtown, The Omni Grove Park Inn is a sanctuary for the soul. Enchanting mountain vistas, lush green fairways, warm Southern charm, and passionate hospitality make The Omni Grove Park Inn an oasis for family vacations. The Omni Grove Park Inn is two miles from downtown Asheville, North Carolina. The hotel is located a short drive to the Biltmore Estate, Blue Ridge Parkway, N orth Carolina A rboretum, and Great Smoky M ountains N ational Park. Downtown Asheville is a vibrant and historic district with colorful sights, historic buildings and spectacular A rt Deco architecture. Explore the charming streets with a collection of restaurants, art galleries, quaint bookstores, eclectic shops, trendy coffee houses, and live music venues. Located three miles from The Omni Grove Park Inn, the Blue Ridge Parkw ay is named A merica s favorite drive and connects the Great Smoky Mountains National Park to Shenandoah N ational Park in Virginia. Enjoy stunning vistas of mountains, meadow s, old farms, and diverse flora and fauna. Discover miles of hiking trails, picnic areas, and scenic overlooks. To secure your room at The Omni Grove Park Inn, please call 800-438-5800 and state that you will be attending the ECH O program. The room rate is $249 single/double. N ote, the resort fee has been w aived for this group event. The resort fee includes: local calling, in-room high speed internet access, entrance to fitness center, in-room coffee/ tea, and new spaper available upon request. On-line Reservations The room block is scheduled to be held until M onday, April 17, 2017 but has been sold out before this date in the past. Therefore, w e advise you to register for the program and reserve your lodging as soon as possible. Check-in: 4:00 p.m. Check-out: 11:00 a.m. We encourage participation by all individuals. If you have a disability, advance notification of any special needs w ill help us better serve you. Lodging arrangements are the sole responsibility of the individual registrant. Department of Cardiovascular Diseases is not responsible for expenses incurred by an individual who is not confirmed and for whom space is not available at the meeting. Costs incurred by the registrant such as airline or hotel fees or penalties are the responsibility of the registrant. PARKING Parking is available at the hotel for an additional cost. SOCIAL PROGRAMS Welcome Reception Wednesday, M ay 17, 2017 6:00-7:00 p.m. A ttendees and their guest(s) are cordially invited to join the course faculty for the Welcome Reception on Wednesday, M ay 17. This casual reception w elcomes you to Asheville, officially opens the course, and offers you the perfect opportunity to make connections w ith existing and new colleagues.

RECREA TION / LEISURE A CTIVITIES The hotel concierge will be pleased to assist with any tours. Biltmore Estate Discount vouchers will be provided. Golfing H arrah s Cherokee Casino N atahala Outdoor Center including river rafting, kayak and canoe trips, mountain biking, hiking, fly fishing, zip lines, climbing and fishing adventures. Blue Ridge Parkw ay Gr eat Smoky M ountain N ational Park Great Smoky M ountain Railroad Excursions Star Watch Night Vision Tours Grandfather M ountain State Park North Carolina Arboretum NEXT YEAR S DATES N ext year s course will be held at the Marriott in Hilton Head Island, SC. Conference dates are M ay 16-19, 2018.

FA CULTY Fletcher A. M iller, Jr., M.D., FA CC, FA HA, FA SE Professor of Medicine, Mayo Clinic; Consultant, Department of Cardiovascular Diseases; Past Director, Cardiovascular Ultrasound Imaging and H emodynamic Laboratory, M ayo Clinic, Rochester, MN Roger L. Click, M.D., Ph.D., FA CC Associate Professor of Medicine, Mayo Clinic; Consultant, Department of Cardiovascular Diseases, M ayo Clinic, Rochester, MN Naser M. A mmash, M.D., FA CC, FA SE Professor of Medicine, Mayo Clinic; Consultant, Department of Cardiovascular Diseases; Vice-Chair for Clinical Practice, Department of Cardiovascular Diseases, Mayo Clinic, Rochester, MN and Jacksonville, FL Pamela R. Burgess, RDCS, RDM S, RVT, FA SE Clinical M anager, Cardiac Ultrasound and Stress Testing Lab, Wake Forest Baptist Health, Winston- Sal em, N C M ayo Faculty Lori A. Blauwet, M.D., M.A., FA CC, FA HA, FA SE Associate Professor of Medicine, Mayo Clinic; Consultant, Department of Cardiovascular Diseases, M ayo Clinic, Rochester, MN Crystal R. Bonnichsen, M.D. Assistant Professor of Medicine, Mayo Clinic; Consultant, Department of Cardiovascular Diseases and Internal Medicine, Mayo Clinic, Rochester, MN A llison K. Cabalka, M.D., FA CC, FA SE Professor of Pediatrics, Mayo Clinic; Consultant, Division of Pediatric Cardiology, Mayo Clinic, Rochester, MN Hari P. Chaliki, M.D., FA CC Associate Professor of Medicine, Mayo Clinic; Consultant, Division of Cardiovascular Diseases; Director, Valvular Heart Disease Clinic, Mayo Clinic, Scottsdale, AZ Michael W. Cullen, M.D., FA CC Assistant Professor of Medicine, Mayo Clinic; Medical Director for the SE Minnesota Regional Cardiologists; Senior Associate Consultant, Department of Cardiovascular Diseases, Mayo Clinic, Rochester, M N Regina (Gina) M. H arper, RDCS Clinical Sonographer, Cardiovascular Ultrasound Imaging and H emodynamic Laboratory, M ayo Clinic, Rochester, M N Garvan C. Kane, M.D., Ph.D., FA SE, FCCP Associate Professor of Medicine, Mayo Clinic; Co-Director, Cardiovascular Ultrasound Imaging and H emodynamic Laboratory; Director of Structural H eart Disease Research; Consultant, Department of Cardiovascular Diseases, Mayo Clinic, Rochester, MN Barry L. Karon, M.D., FA CC, FA SE Assistant Professor of Medicine, Mayo Clinic; Consultant, Department of Cardiovascular Diseases, M ayo Clinic, Rochester, MN

Rebecca (Becky) C. Klug, RDCS, (RT) R Clinical Instructor, M ayo School of Health Sciences Echocardiography Program; Clinical and Congenital Sonographer, Cardiovascular Ultrasound Imaging and H emodynamic Laboratory, M ayo Clinic, Rochester, M N A my W. Pollak, M.D., M.S. Assistant Professor of Medicine, Mayo Clinic; Consultant, Department of Cardiovascular Diseases, M ayo Clinic, Jacksonville, FL Jeremy J. Thaden, M.D. Senior Associate Consultant, Mayo Clinic; Department of Cardiovascular Diseases, Mayo Clinic, Rochester, M N Guest Faculty Beverly Gorman, RDCS Director of A ccreditation IAC Echocardiography, Ellicott City, MD Frederick W. Kremkau, Ph.D., FA CR, FA IMBE, FA IUM, FA SA Past President, A merican Institute of Ultrasound in Medicine; Professor and Co-Director, Program for Medical Ultrasound, Center for Applied Learning, Wake Forest University School of Medicine, Winston- Sal em, N C Thomas Ryan, M.D., FA CC, FA SE Professor of M edicine; Director, The Ohio State University Heart Center; John G. and Jeanne Bonnet McCoy Chair in Cardiovascular Medicine, Davis Heart & Lung Research Institute, Columbus, OH FACULTY DISCLOSURE As a provider accredited by ACCME, Mayo Clinic College of Medicine (Mayo School of Continuous Professional Development) must ensure balance, independence, objectivity and scientific rigor in its educational activities. Course director(s), planning committee, faculty, and all others who are in a position to control the content of this educational activity are required to disclose all relevant financial relationships with any commercial interest related to the subject matter of the educational activity. Safeguards against commercial bias have been put in place. Faculty also will disclose any off-label and/ or investigational use of pharmaceuticals or instruments discussed in their presentation. Disclosure of this information will be published in course materials so those participants in the activity may formulate their ow n judgments regarding the presentation.

TUESD AY, M AY 16, 2017 6:00-7:00 p.m. Pre-Registration H eritage Foyer WED N ESD AY, M AY 17, 2017 7:00 a.m. Registration and Continental Breakfast H eritage Foyer 7:30 a.m. Welcome Roger L. Click, M.D., Ph.D. FUNDAMENTALS Dr. Roger L. Click, presiding 7:40 a.m. Cases - Teasers Drs. Miller, Click, and Ammash 8:00 a.m. A ssessment of LV Systolic Function in 2017 Amy W. Pollak, M.D. 8:30 a.m. Diastolic Function Updates Fletcher A. Miller, Jr., M.D. 9:00 a.m. Real or Echo A rtifact? Fr eder i ck W. Kremkau, Ph.D. and Pam Burgess, RDCS, RDMS, RVT 9:30 a.m. RV Function in 2017 Garvan C. Kane, M.D., Ph.D. 10:00 a.m. Panel Discussion Drs. Pollak, Miller, Kr emkau, and Kane; Dr. Click, moderator 10:15 a.m. Refreshment Break 10:45 a.m. Challenging Cases for A ssessment of Pulmonary Pressures Michael W. Cullen, M.D. 11:00 a.m. Echo in Congestive Heart Failure: When and Why Barry L. Karon, M.D. 11:30 a.m. Echo in Restrictive Cardiomyopathies Naser M. Ammash, M.D. 12:00 p.m. Challenging H eart Failure Case Lori A. Blauwet, M.D. 12:15 p.m. Panel Discussion Drs. Cullen, Karon, Ammash, and Blauwet; Dr. Click, moderator 12:30 p.m. Lunch H eritage C ECHO FOR M YOCARDIAL AND PERICARDIAL DISEASE D r. Fl et cher A. M i ller, Jr., presiding 1:30 p.m. Echo A ssessment of H CM Hari P. Chaliki, M.D.

2:00 p.m. Cardiac Constriction Barry L. Karon, M.D. 2:30 p.m. Strain for M yocardial Diseases Fletcher A. Miller, Jr., M.D. 3:00 p.m. Panel Discussion Drs. Chaliki and Karon; Dr. M iller, moderator 3:15 p.m. Refreshment Break PARELLEL SESSI ONS SONOGRAPH ERS (Foyer) TEE (M ain Ballroom) 3:45-4:15 p.m. Sonographer Hands-on M s. Burgess, M s. Harper, and M s. Klug TEE for Source of Embolism Cases Roger L. Click, M.D., Ph.D. 4:15-4:45 p.m. TEE for Endocarditis Cases Jer emy J. Thaden, M.D. 4:45-5:00 p.m. Questions and A nsw ers 5:00 p.m. Adjourn Adjourn 6:00-7:00 p.m. Welcome Reception Skyline Room, Mountainview Terrace, Sammons Wing, 8 th Floor (A t t endees, guests, and faculty invited.) THURSD AY, M AY 18, 2017 7:00 a.m. Continental Breakfast H eritage Foyer I SCH EM I C H EART D I SEASE/AORTIC D I SEASE Dr. Naser M. Ammash, presiding 7:30 a.m. Contrast Echocardiography Thomas Ryan, M.D. 8:00 a.m. Cases in Exercise and Pharmacologic Stress Echo for Coronary Disease Michael W. Cullen, M.D. 8:30 a.m. Echo for Acute Coronary Syndromes Roger L. Click, M.D., Ph.D. 9:00 a.m. Cases for Coronary Artery Disease Amy W. Pollak, M.D. 9:30 a.m. Panel Discussion Drs. Ryan, Cullen, Click, and Pollak; Dr. Ammash, moderator 10:00 a.m. Refreshment Break 10:30 a.m. Surprises in Stress Echo Good and Bad Thomas Ryan, M.D. 11:00 a.m. Multimodality Imaging for A cute A ortic Syndromes Crystal R. Bonnichsen, M.D.

11:30 a.m. Value of Echo vs CT in Coronary Artery Anomalies Naser M. Ammash, M.D. 12:00 p.m. Panel Discussion Drs. Ryan and Bonnichsen; Dr. Ammash, moderator 12:30 p.m. Adjourn for the Afternoon IAC Echocardiography Accreditation Workshop Bring your laptop to work on your application. M s. Beverly Gorman (Sr. Director IAC) and M s. Pamela R. Burgess Time Agenda I tem 3:00-3:05 p.m. Welcome Gorman, Burgess 3:05-3:40 p.m. Brief overview of the IAC Echocardiography history and information regarding the structure of the IAC Why it was created, history. Purpose of accreditation, w hat it is, what it is not. Who the sponsoring organizations are and their role. IAC Echocardiography Board of Directors and their responsibilities. A bout the standards, basis for the program, minimum standards. Company mission - improving health care through accreditation. Reimbursement what the IAC does and doesn t do. 3:40-4:30 p.m. Steps to earning accreditation, reaccreditation Gather information w hat is needed to complete the application. Internal self-assessment what it is and how to perform, using the standards as their guide (attendees are encouraged bring their policies, protocols). Tips and questions answ ered on how to review. Case study requirements how many, what pathology, how to pick cases (w hat if it s not a perfect case?), final reports (how to review ). Sample documents. 4:30-4:45 p.m. D inner Break 4:45-5:30 p.m. Quality Improvement What it is, detailed discussion on the required QI measures (w hat they are, how much is required and how often). QI tool if used, meets the requirements, view w ebcast. Used for audits. QI meetings, what should be discussed, how many, who needs to attend, meeting minutes. 5:30-5:45 p.m. The online application overview of the application, questions and attachments 5:45-5:50 p.m. Pre-submission check what it is and what it isn t 5:50-6:00 p.m. Final submission, what happens next 6:00-6:20 p.m. Application decisions What they are and w hat to do if delayed. Decision letters and application review findings 6:20-6:30 p.m. How your lab should run on a daily basis 6:30-6:40 p.m. Resources overview of the website, samples, On D emand, live webinars 6:40-7:00 p.m. Closing Q&A

FRI D AY, M AY 19, 2017 7:00 a.m. Continental Breakfast H eritage Foyer ECH O FOR V ALV E D I SEASE Dr. Roger L. Click, presiding 7:30 a.m. Echo for Aortic Stenosis: How To Fl et cher A. Miller, Jr., M.D. 8:00 a.m. Low Output Low Gradient Aortic Stenosis Hari P. Chaliki, M.D. 8:30 a.m. Echo for Aortic Regurgitation Thomas Ryan, M.D. 9:00 a.m. Echo for Right-Sided Valves Garvan C. Kane, M.D., Ph.D. 9:30 a.m. Panel Discussion Drs. Miller, Chaliki, Ryan, and Kane; Dr. Click, moderator 10:00 a.m. Refreshment Break 10:30 a.m. Echo for Mitral Regurgitation: How To Quantify Lori A. Blauwet, M.D. 11:00 a.m. 3-D/TEE for Mitral Valve Interventions Jer emy J. Thaden, M.D. 11:30 a.m. Cases in Stress Echo for H emodynamic A ssessment Garvan C Kane, M.D., Ph.D. 12:00 p.m. Panel Discussion Drs. Blauwet, Thaden, and Kane; Dr. Click, moderator 12:30 p.m. Lunch H eritage C

PARELLEL SESSI ONS CONGENITAL HEART D I SEASE (M ain Ballroom) Dr. Naser M. Ammash, presiding 1:30-2:00 p.m. Echocardiography in the Evaluation of RV Enlargement. Where Is That Shunt? Naser M. Ammash, M.D. 2:00-2:30 p.m. Echo in Postop Simple Congenital H eart Disease Crystal R. Bonnichsen, M.D. 2:30-3:00 p.m. Interventional Echo for Congenital H eart Disease Allison K. Cabalka, M.D. 3:00-3:30 p.m. Panel Discussion Drs. Ammash, Bonnichsen, and Cabalka; Dr. Ammash, moderator 3:30 p.m. Adjourn Adjourn TEE SI M ULATOR (Foyer) Dr. Fletcher A. M iller, Jr., M s. Klug, and M s. Harper SATURDAY, MAY 20, 2017 7:00 a.m. Continental Breakfast H eritage Foyer M ORE VALVULAR AND SPECI AL TOPI CS Dr. Roger L. Click, presiding 7:30 a.m. Echo for Aortic Prostheses Jer emy J. Thaden, M.D. 8:00 a.m. Echo for TAVR: Pre and Post Hari P. Chaliki, M.D. 8:30 a.m. Echo for M itral Prostheses Lori A. Blauwet, M.D. 9:00 a.m. Cardiac M asses Roger L. Click, M.D., Ph.D. 9:30 a.m. Panel Discussion Drs. Thaden, Chaliki, and Blauwet; Dr. Click, moderator 9:45 a.m. Refreshment Break 10:00 a.m. Case Competition: You Be the Judge! Dr. Thomas Ryan, moderator Drs. Bonnichsen, Cullen, Pollak, Kr emkau, Karon, Cabalka, and M s. Burgess 11:45 a.m. Adjourn

Registration Online Registration Fee: Course Registration (M D, PhD, DO, PharmD) $750.00 Course Registration (Fellows in Training, Sono, RN ) $565.00 Mayo Clinic Department of Cardiovascular Diseases implemented an online conference registration system in January 2012. If this is your first time using the online system, you will need to create a profile. The attendee s email address is required upon registration. A letter of confirmation and receipt will be forw arded to this email address upon receipt of submitted registration and payment. Present this letter when checking in at the meeting registration desk. The registration fee includes tuition, electronic course syllabus, continental breakfasts, break refreshments, lunch, and reception. Although it is not Department of Cardiovascular Diseases policy to limit the number of registrants for a course, conference room facilities may necessitate closing of enrollment; therefore, early registration is advised. Enrollment for this program is limited. For additional information, contact: Cardiovascular Continuing Education 200 First Street SW Gonda 6-138 Rochester, M N 55905 E-mail: cvcme@mayo.edu Phone: 800-283-6296 or 507-266-6703 Website CANCELLATION POLICY If you cancel your participation in this course, your registration fee, less a $75 administrative fee, will be refunded w hen w ritten notification is received by Department of Cardiovascular Diseases (CV CME) before Wednesday, M ay 3, 2017 (cvcme@mayo.edu or fax#: 507-266-7403). N o refunds w ill be made on or after Wednesday, M ay 3, 2017. Canceled registrations are non-transferable. CV CME reserves the right to cancel or postpone any course due to unforeseen circumstances. In the unlikely event CV CME must cancel or postpone this course, CV CME w ill refund the registration fee, but is not responsible for any related costs, charges, or expenses to participants, including fees assessed by airline/ travel/ lodging agencies.