SydPath Reference Intervals for Clinical Trials (Contract Pathology Unit) Unauthorised Copy

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HAEMATOLOGY APTT 1 150 M 25 35 sec APTT 1 150 F 25 35 sec Basophils Cord 2 weeks M 0.0 0.4 10^9/L Basophils Cord 2 weeks F 0.0 0.4 10^9/L Basophils 2 wks 3 mths M 0.0 0.2 10^9/L Basophils 2 wks 3 mths F 0.0 0.2 10^9/L Basophils 3 mths 6 mths M 0.0 0.1 10^9/L Basophils 3 mths 6 mths F 0.0 0.1 10^9/L Basophils 6 mths 2 yrs M 0.0 0.1 10^9/L Basophils 6 mths 2 yrs F 0.0 0.1 10^9/L Basophils 2 yrs 4 yrs M 0.0 0.1 10^9/L Basophils 2 yrs 4 yrs F 0.0 0.1 10^9/L Basophils 4 yrs 8 yrs M 0.0 0.1 10^9/L Basophils 4 yrs 8 yrs F 0.0 0.1 10^9/L Basophils 8 yrs 12 yrs M 0.0 0.1 10^9/L Basophils 8 yrs 12 yrs F 0.0 0.1 10^9/L Basophils 12 150 M 0.0 0.1 10^9/L Basophils 12 150 F 0.0 0.1 10^9/L Basophils 0 150 M % Basophils 0 150 F % Eosinophils Cord 2 weeks M 0.0 1.3 10^9/L Eosinophils Cord 2 weeks F 0.0 1.3 10^9/L Eosinophils 2 wks 3 mths M 0.0 1.0 10^9/L Eosinophils 2 wks 3 mths F 0.0 1.0 10^9/L Eosinophils 3 mths 6 mths M 0.0 1.0 10^9/L Eosinophils 3 mths 6 mths F 0.0 1.0 10^9/L Eosinophils 6 mths 2 yrs M 0.0 1.0 10^9/L Eosinophils 6 mths 2 yrs F 0.0 1.0 10^9/L Eosinophils 2 yrs 4 yrs M 0.0 1.0 10^9/L Eosinophils 2 yrs 4 yrs F 0.0 1.0 10^9/L Eosinophils 4 yrs 8 yrs M 0.0 1.0 10^9/L Eosinophils 4 yrs 8 yrs F 0.0 1.0 10^9/L Eosinophils 8 yrs 12 yrs M 0.0 1.0 10^9/L Eosinophils 8 yrs 12 yrs F 0.0 1.0 10^9/L Eosinophils 12 150 M 0.0 0.4 10^9/L Eosinophils 12 150 F 0.0 0.4 10^9/L Eosinophils 0 150 M % Eosinophils 0 150 F % Erythropoietin 1 150 M 4 19 miu/ml Erythropoietin 1 150 F 4 19 miu/ml ESR 12 150 M 0 10 mm/h ESR 12 150 F 0 10 mm/h Fibrinogen 0 150 M 2.0 4.0 g/l Fibrinogen 0 150 F 2.0 4.0 g/l Haematocrit Cord 2 weeks M 0.37 0.60 Haematocrit Cord 2 weeks F 0.37 0.60 Haematocrit 2 wks 3 mths M 0.30 0.40 Haematocrit 2 wks 3 mths F 0.30 0.40 Haematocrit 3 mths 6 mths M 0.28 0.40 Haematocrit 3 mths 6 mths F 0.28 0.40 Haematocrit 6 mths 2 yrs M 0.30 0.40 Haematocrit 6 mths 2 yrs F 0.30 0.40 Haematocrit 2 yrs 4 yrs M 0.30 0.40 Haematocrit 2 yrs 4 yrs F 0.30 0.40 Haematocrit 4 yrs 8 yrs M 0.30 0.40 Haematocrit 4 yrs 8 yrs F 0.30 0.40 Haematocrit 8 yrs 12 yrs M 0.30 0.45 Haematocrit 8 yrs 12 yrs F 0.30 0.45 Haematocrit 12 150 M 0.40 0.54 Haematocrit 12 150 F 0.37 0.47 Haemoglobin Cord 2 weeks M 120 220 g/l Haemoglobin Cord 2 weeks F 120 220 g/l Haemoglobin 2 wks 3 mths M 100 130 g/l Haemoglobin 2 wks 3 mths F 100 130 g/l Haemoglobin 3 mths 6 mths M 100 120 g/l Haemoglobin 3 mths 6 mths F 100 120 g/l Haemoglobin 6 mths 2 yrs M 100 130 g/l LOC:3 Auth: Contract Pathology Manager Effective Date: 5th March 2010 Page 1 of 12

HAEMATOLOGY Haemoglobin 6 mths 2 yrs F 100 130 g/l Haemoglobin 2 yrs 4 yrs M 100 140 g/l Haemoglobin 2 yrs 4 yrs F 100 140 g/l Haemoglobin 4 yrs 8 yrs M 110 140 g/l Haemoglobin 4 yrs 8 yrs F 110 140 g/l Haemoglobin 8 yrs 12 yrs M 110 145 g/l Haemoglobin 8 yrs 12 yrs F 110 145 g/l Haemoglobin 12 150 M 130 180 g/l Haemoglobin 12 150 F 115 165 g/l INR 0 150 M INR 0 150 F Lymphocytes Cord 2 weeks M 2.0 9.0 10^9/L Lymphocytes Cord 2 weeks F 2.0 9.0 10^9/L Lymphocytes 2 wks 3 mths M 3.0 9.0 10^9/L Lymphocytes 2 wks 3 mths F 3.0 9.0 10^9/L Lymphocytes 3 mths 6 mths M 3.0 10.0 10^9/L Lymphocytes 3 mths 6 mths F 3.0 10.0 10^9/L Lymphocytes 6 mths 2 yrs M 2.0 9.0 10^9/L Lymphocytes 6 mths 2 yrs F 2.0 9.0 10^9/L Lymphocytes 2 yrs 4 yrs M 2.0 7.0 10^9/L Lymphocytes 2 yrs 4 yrs F 2.0 7.0 10^9/L Lymphocytes 4 yrs 8 yrs M 1.5 5.5 10^9/L Lymphocytes 4 yrs 8 yrs F 1.5 5.5 10^9/L Lymphocytes 8 yrs 12 yrs M 1.5 4.5 10^9/L Lymphocytes 8 yrs 12 yrs F 1.5 4.5 10^9/L Lymphocytes 12 150 M 1.5 4.0 10^9/L Lymphocytes 12 150 F 1.5 4.0 10^9/L Lymphocytes 0 150 M % Lymphocytes 0 150 F % MCH Cord 2 weeks M 30.0 38.0 pg MCH Cord 2 weeks F 30.0 38.0 pg MCH 2 wks 3 mths M 29.0 34.0 pg MCH 2 wks 3 mths F 29.0 34.0 pg MCH 3 mths 6 mths M 23.0 30.0 pg MCH 3 mths 6 mths F 23.0 30.0 pg MCH 6 mths 2 yrs M 23.0 30.0 pg MCH 6 mths 2 yrs F 23.0 30.0 pg MCH 2 yrs 4 yrs M 23.0 30.0 pg MCH 2 yrs 4 yrs F 23.0 30.0 pg MCH 4 yrs 8 yrs M 26.0 31.0 pg MCH 4 yrs 8 yrs F 26.0 31.0 pg MCH 8 yrs 12 yrs M 26.0 31.0 pg MCH 8 yrs 12 yrs F 26.0 31.0 pg MCH 12 150 M 27.0 32.0 pg MCH 12 150 F 27.0 32.0 pg MCHC 0 150 M 320 360 g/l MCHC 0 150 F 320 360 g/l MCV Cord 2 weeks M 100 120 fl MCV Cord 2 weeks F 100 120 fl MCV 2 wks 3 mths M 84 100 fl MCV 2 wks 3 mths F 84 100 fl MCV 3 mths 6 mths M 68 85 fl MCV 3 mths 6 mths F 68 85 fl MCV 6 mths 2 yrs M 70 85 fl MCV 6 mths 2 yrs F 70 85 fl MCV 2 yrs 4 yrs M 70 90 fl MCV 2 yrs 4 yrs F 70 90 fl MCV 4 yrs 8 yrs M 75 90 fl MCV 4 yrs 8 yrs F 75 90 fl MCV 8 yrs 12 yrs M 75 90 fl MCV 8 yrs 12 yrs F 75 90 fl MCV 12 150 M 76 96 fl MCV 12 150 F 76 96 fl Monocytes Cord 2 weeks M 0.2 4.0 10^9/L Monocytes Cord 2 weeks F 0.2 4.0 10^9/L Monocytes 2 wks 3 mths M 0.2 1.1 10^9/L Monocytes 2 wks 3 mths F 0.2 1.1 10^9/L LOC:3 Auth: Contract Pathology Manager Effective Date: 5th March 2010 Page 2 of 12

HAEMATOLOGY Monocytes 3 mths 6 mths M 0.2 1.1 10^9/L Monocytes 3 mths 6 mths F 0.2 1.1 10^9/L Monocytes 6 mths 2 yrs M 0.2 1.1 10^9/L Monocytes 6 mths 2 yrs F 0.2 1.1 10^9/L Monocytes 2 yrs 4 yrs M 0.2 1.0 10^9/L Monocytes 2 yrs 4 yrs F 0.2 1.0 10^9/L Monocytes 4 yrs 8 yrs M 0.2 1.0 10^9/L Monocytes 4 yrs 8 yrs F 0.2 1.0 10^9/L Monocytes 8 yrs 12 yrs M 0.2 1.0 10^9/L Monocytes 8 yrs 12 yrs F 0.2 1.0 10^9/L Monocytes 12 150 M 0.2 1.0 10^9/L Monocytes 12 150 F 0.2 1.0 10^9/L Monocytes 0 150 M % Monocytes 0 150 F % Neutrophils Cord 2 weeks M 4.0 21.0 10^9/L Neutrophils Cord 2 weeks F 4.0 21.0 10^9/L Neutrophils 2 wks 3 mths M 1.0 5.0 10^9/L Neutrophils 2 wks 3 mths F 1.0 5.0 10^9/L Neutrophils 3 mths 6 mths M 1.0 4.5 10^9/L Neutrophils 3 mths 6 mths F 1.0 4.5 10^9/L Neutrophils 6 mths 2 yrs M 1.0 6.0 10^9/L Neutrophils 6 mths 2 yrs F 1.0 6.0 10^9/L Neutrophils 2 yrs 4 yrs M 1.5 7.0 10^9/L Neutrophils 2 yrs 4 yrs F 1.5 7.0 10^9/L Neutrophils 4 yrs 8 yrs M 1.5 8.0 10^9/L Neutrophils 4 yrs 8 yrs F 1.5 8.0 10^9/L Neutrophils 8 yrs 12 yrs M 1.5 8.0 10^9/L Neutrophils 8 yrs 12 yrs F 1.5 8.0 10^9/L Neutrophils 12 150 M 2.0 7.5 10^9/L Neutrophils 12 150 F 2.0 7.5 10^9/L Neutrophils 0 150 M % Neutrophils 0 150 F % Platelets Cord 2 weeks M 150 450 10^9/L Platelets Cord 2 weeks F 150 450 10^9/L Platelets 2 wks 3 mths M 200 650 10^9/L Platelets 2 wks 3 mths F 200 650 10^9/L Platelets 3 mths 6 mths M 200 650 10^9/L Platelets 3 mths 6 mths F 200 650 10^9/L Platelets 6 mths 2 yrs M 200 550 10^9/L Platelets 6 mths 2 yrs F 200 550 10^9/L Platelets 2 yrs 4 yrs M 200 500 10^9/L Platelets 2 yrs 4 yrs F 200 500 10^9/L Platelets 4 yrs 8 yrs M 200 500 10^9/L Platelets 4 yrs 8 yrs F 200 500 10^9/L Platelets 8 yrs 12 yrs M 150 450 10^9/L Platelets 8 yrs 12 yrs F 150 450 10^9/L Platelets 12 150 M 150 400 10^9/L Platelets 12 150 F 150 400 10^9/L PT 1 150 M 11 15 sec PT 1 150 F 11 15 sec RBC Cord 2 weeks M 3.3 5.4 10^12L RBC Cord 2 weeks F 3.3 5.4 10^12L RBC 2 wks 3 mths M 3.3 4.0 10^12L RBC 2 wks 3 mths F 3.3 4.0 10^12L RBC 3 mths 6 mths M 3.3 4.9 10^12L RBC 3 mths 6 mths F 3.3 4.9 10^12L RBC 6 mths 2 yrs M 3.8 5.1 10^12L RBC 6 mths 2 yrs F 3.8 5.1 10^12L RBC 2 yrs 4 yrs M 3.8 5.1 10^12L RBC 2 yrs 4 yrs F 3.8 5.1 10^12L RBC 4 yrs 8 yrs M 3.9 5.1 10^12L RBC 4 yrs 8 yrs F 3.9 5.1 10^12L RBC 8 yrs 12 yrs M 3.9 5.2 10^12L RBC 8 yrs 12 yrs F 3.9 5.2 10^12L RBC 12 150 M 4.5 6.5 10^12L RBC 12 150 F 3.8 5.8 10^12L RDW Cord 2 weeks M 11.5 20.0 % LOC:3 Auth: Contract Pathology Manager Effective Date: 5th March 2010 Page 3 of 12

HAEMATOLOGY RDW Cord 2 weeks F 11.5 20.0 % RDW 2 wks 3 mths M 11.5 16.0 % RDW 2 wks 3 mths F 11.5 16.0 % RDW 3 mths 6 mths M 11.5 16.0 % RDW 3 mths 6 mths F 11.5 16.0 % RDW 6 mths 2 yrs M 11.5 16.0 % RDW 6 mths 2 yrs F 11.5 16.0 % RDW 2 yrs 4 yrs M 11.5 16.0 % RDW 2 yrs 4 yrs F 11.5 16.0 % RDW 4 yrs 8 yrs M 11.5 15.0 % RDW 4 yrs 8 yrs F 11.5 15.0 % RDW 8 yrs 12 yrs M 11.5 14.5 % RDW 8 yrs 12 yrs F 11.5 14.5 % RDW 12 150 M 11.5 14.5 % RDW 12 150 F 11.5 14.5 % Reticulocytes Cord 2 weeks M % Reticulocytes Cord 2 weeks F % Reticulocytes 2 wks 3 mths M 0.5 2.5 % Reticulocytes 2 wks 3 mths F 0.5 2.5 % Reticulocytes 3 mths 6 mths M 0.5 2.5 % Reticulocytes 3 mths 6 mths F 0.5 2.5 % Reticulocytes 6 mths 2 yrs M 0.5 2.5 % Reticulocytes 6 mths 2 yrs F 0.5 2.5 % Reticulocytes 2 yrs 4 yrs M 0.5 2.5 % Reticulocytes 2 yrs 4 yrs F 0.5 2.5 % Reticulocytes 4 yrs 8 yrs M 0.5 2.5 % Reticulocytes 4 yrs 8 yrs F 0.5 2.5 % Reticulocytes 8 yrs 12 yrs M 0.5 2.5 % Reticulocytes 8 yrs 12 yrs F 0.5 2.5 % Reticulocytes 12 150 M 0.5 2.5 % Reticulocytes 12 150 F 0.5 2.5 % Reticulocytes Cord 2 weeks M n/a n/a 10^9/L Reticulocytes Cord 2 weeks F n/a n/a 10^9/L Reticulocytes 2 wks 3 mths M 20 65 10^9/L Reticulocytes 2 wks 3 mths F 20 65 10^9/L Reticulocytes 3 mths 6 mths M 20 105 10^9/L Reticulocytes 3 mths 6 mths F 20 105 10^9/L Reticulocytes 6 mths 2 yrs M 20 105 10^9/L Reticulocytes 6 mths 2 yrs F 20 105 10^9/L Reticulocytes 2 yrs 4 yrs M 20 105 10^9/L Reticulocytes 2 yrs 4 yrs F 20 105 10^9/L Reticulocytes 4 yrs 8 yrs M 20 105 10^9/L Reticulocytes 4 yrs 8 yrs F 20 105 10^9/L Reticulocytes 8 yrs 12 yrs M 20 105 10^9/L Reticulocytes 8 yrs 12 yrs F 20 105 10^9/L Reticulocytes 12 150 M 20 110 10^9/L Reticulocytes 12 150 F 20 110 10^9/L Thrombin Time 1 150 M 10 12 sec Thrombin Time 1 150 F 10 12 sec WBC Cord 2 weeks M 9.0 30.0 10^9/L WBC Cord 2 weeks F 9.0 30.0 10^9/L WBC 2 wks 3 mths M 5.0 14.0 10^9/L WBC 2 wks 3 mths F 5.0 14.0 10^9/L WBC 3 mths 6 mths M 5.0 14.0 10^9/L WBC 3 mths 6 mths F 5.0 14.0 10^9/L WBC 6 mths 2 yrs M 5.0 14.0 10^9/L WBC 6 mths 2 yrs F 5.0 14.0 10^9/L WBC 2 yrs 4 yrs M 5.0 13.0 10^9/L WBC 2 yrs 4 yrs F 5.0 13.0 10^9/L WBC 4 yrs 8 yrs M 4.5 13.0 10^9/L WBC 4 yrs 8 yrs F 4.5 13.0 10^9/L WBC 8 yrs 12 yrs M 4.5 13.0 10^9/L WBC 8 yrs 12 yrs F 4.5 13.0 10^9/L WBC 12 150 M 4.0 11.0 10^9/L WBC 12 150 F 4.0 11.0 10^9/L LOC:3 Auth: Contract Pathology Manager Effective Date: 5th March 2010 Page 4 of 12

CHEMISTRY 25 - OH Vit D 0 150 M 35 150 nmol/l 25 - OH Vit D 0 150 F 35 150 nmol/l Albumin 0 150 M 36 52 g/l Albumin 0 150 F 36 52 g/l Albumin excre. 0 150 M 0 29.0 mg/d Albumin excre. 0 150 F 0 29.0 mg/d Alk. phos. 0 5 M 70 320 U/L Alk. phos. 5 10 M 140 360 U/L Alk. phos. 10 15 M 90 480 U/L Alk. phos. 15 19 M 70 360 U/L Alk. phos. 19 150 M 30 100 U/L Alk. phos. 0 9 F 140 360 U/L Alk. phos. 9 15 F 50 400 U/L Alk. phos. 15 19 F 50 130 U/L Alk. phos. 19 150 F 30 100 U/L ALT 0 150 M 0 30 U/L ALT 0 150 F 0 30 U/L Amylase 0 150 M 0 100 U/L Amylase 0 150 F 0 100 U/L AST 0 150 M 0 30 U/L AST 0 150 F 0 30 U/L Bicarbonate 0 150 M 24 31 mmol/l Bicarbonate 0 150 F 24 31 mmol/l Bilirubin - conj. * 0 150 M 0 10 umol/l Bilirubin - conj. * 0 150 F 0 10 umol/l Bilirubin - Total * 0 150 M 0 18 umol/l Bilirubin - Total * 0 150 F 0 18 umol/l Bilirubin - Unconj. * 0 150 M 0 18 umol/l Bilirubin - Unconj. * 0 150 F 0 18 umol/l Caeruloplasmin 0 150 M 250 630 mg/l Caeruloplasmin 0 150 F 250 630 mg/l Calcium 0 150 M 2.10 2.60 mmol/l Calcium 0 150 F 2.10 2.60 mmol/l Chloride 0 150 M 95 110 mmol/l Chloride 0 150 F 95 110 mmol/l Cholesterol 0 150 M 0 6.0 mmol/l Cholesterol 0 150 F 0 6.0 mmol/l Cortisol 0 150 M 200 700 nmol/l Cortisol 0 150 F 200 700 nmol/l C-peptide 0 150 M 0.7 2.5 ug/l C-peptide 0 150 F 0.7 2.5 ug/l Creat. excret. 0 150 M 5 16 mmol/d Creat. excret. 0 150 F 5 16 mmol/d Creat.Cl(calc) 0 150 M 1.5 2.5 ml/s Creat.Cl(calc) 0 150 F 1.5 2.5 ml/s Creat.Cl(calc) 0 150 M 90 150 ml/min Creat.Cl(calc) 0 150 F 90 150 ml/min Creatinine kinase 0 150 M 0 130 U/L Creatinine kinase 0 150 F 0 110 U/L CKMB 0 150 M 0 5.0 ug/l CKMB 0 150 F 0 5.0 ug/l Creatinine 0 150 M 60 120 umol/l Creatinine 0 150 F 40 90 umol/l CRP 0 150 M <10.0 mg/l CRP 0 150 F <10.0 mg/l Digoxin 0 150 M 0.5 1.0 ug/l Digoxin 0 150 F 0.5 1.0 ug/l Ferritin 0 16 M 20 200 ug/l Ferritin 16 150 M 30 400 ug/l LOC:3 Auth: Contract Pathology Manager Effective Date: 5th March 2010 Page 5 of 12

CHEMISTRY Ferritin 0 16 F 20 200 ug/l Ferritin 16 50 F 15 150 ug/l Ferritin 50 150 F 30 400 ug/l Free T3 1 150 M 3.0 6.2 pmol/l 08/10/09 Free T3 1 150 F 3.0 6.2 pmol/l 08/10/09 Free Testost. 0 150 M 31.0 163.0 pmol/l Free Testost. 0 150 F 2.4 12.5 pmol/l Free thyroxine* 1 150 M 11.0 22.0 pmol/l 08/10/09 Free thyroxine* 1 150 F 11.0 22.0 pmol/l 08/10/09 GGT 0 150 M 0 35 U/L GGT 0 150 F 0 35 U/L Globulins 0 150 M 22 38 g/l Globulins 0 150 F 22 38 g/l Glucose-fasting 0 150 M 3.0 5.5 mmol/l Glucose-fasting 0 150 F 3.0 5.5 mmol/l Glucose-random 0 150 M 3.0 7.8 mmol/l Glucose-random 0 150 F 3.0 7.8 mmol/l Growth hormone 0 150 M 0 10.0 mu/l Growth hormone 0 150 F 0 10.0 mu/l HBA1c 1 0 150 M <6.0 % HBA1c 1 0 150 F <6.0 % HDL Cholesterol 0 150 M >1.0 mmol/l HDL Cholesterol 0 150 F >1.0 mmol/l Insulin 0 150 M 0.0 17.0 mu/l Insulin 0 150 F 0.0 17.0 mu/l Ionised calcium 0 150 M 1.15 1.30 mmol/l Ionised calcium 0 150 F 1.15 1.30 mmol/l Lactate 0 150 M 0.0 2.2 mmol/l Lactate 0 150 F 0.0 2.2 mmol/l LDH 0 150 M 0 430 U/L LDH 0 150 F 0 430 U/L LDL Cholesterol 0 150 M 0.0 4.0 mmol/l LDL Cholesterol 0 150 F 0.0 4.0 mmol/l Lipase 0 150 M 0 60 U/L Lipase 0 150 F 0 60 U/L Magnesium 0 150 M 0.70 1.05 mmol/l Magnesium 0 150 F 0.70 1.05 mmol/l MB Index 0 150 M 0.0 3.0 MB Index 0 150 F 0.0 3.0 Neopterin 0 150 M 0 13 nmol/l Neopterin 0 150 F 0 13 nmol/l Osmolality 0 150 M 275 295 mm/kg Osmolality 0 150 F 275 295 mm/kg Osteocalcin 0 150 M 3.0 18.0 ug/l Osteocalcin 0 150 F 3.0 18.0 ug/l Phosphate 0 150 M 0.70 1.40 mmol/l Phosphate 0 150 F 0.70 1.40 mmol/l Potassium 0 150 M 3.5 5.0 mmol/l Potassium 0 150 F 3.5 5.0 mmol/l Prealbumin 0 150 M 190 400 mg/l Prealbumin 0 150 F 190 400 mg/l Prolactin 0 150 M 50 350 miu/l 24/11/09 Prolactin 0 150 F 50 500 miu/l 24/11/09 PSA 20 40 M 0.00 2.50 ug/l 23/02/10 LOC:3 Auth: Contract Pathology Manager Effective Date: 5th March 2010 Page 6 of 12

CHEMISTRY PSA 40 50 M 0.00 3.00 ug/l 23/02/10 PSA 50 60 M 0.00 4.00 ug/l 23/02/10 PSA 60 150 M 0.00 5.50 ug/l 23/02/10 PTH (Intact) 0 150 M 1.0 7.0 pmol/l PTH (Intact) 0 150 F 1.0 7.0 pmol/l PTHrP 1 0 150 M <1.3 pmol/l PTHrP 1 0 150 F <1.3 pmol/l Red Cell Folate 0 150 M > 630 nmol/l Red Cell Folate 0 150 F > 630 nmol/l Serum B12 0 150 M >180 pmol/l Serum B12 0 150 F >180 pmol/l Serum Folate 1 150 M > 8.0 nmol/l Serum Folate 1 150 F > 8.0 nmol/l Serum Iron 1 150 M 10 30 umol/l Serum Iron 1 150 F 10 30 umol/l SHBG 0 150 M 10.0 70.0 nmol/l SHBG 0 150 F 20.0 120.0 nmol/l Sodium 0 150 M 137 146 mmol/l Sodium 0 150 F 137 146 mmol/l Total protein 0 150 M 66 82 g/l Total protein 0 150 F 66 82 g/l Transferrin 1 150 M 2.0 3.5 g/l Transferrin 1 150 F 2.0 3.5 g/l Transferrin Sat 1 150 M 15 50 % Transferrin Sat 1 150 F 15 50 % Triglycerides 0 150 M 0.0 2.0 mmol/l Triglycerides 0 150 F 0.0 2.0 mmol/l Troponin I 1 0 150 M <0.06 ug/l Troponin I 1 0 150 F <0.06 ug/l TSH* 1 150 M 0.40 4.20 miu/l 08/10/09 TSH* 1 150 F 0.40 4.20 miu/l 08/10/09 Urea 0 150 M 3.0 8.5 mmol/l Urea 0 150 F 3.0 8.5 mmol/l Uric acid 0 150 M 0.25 0.50 mmol/l Uric acid 0 150 F 0.20 0.40 mmol/l Urine Amylase (spot) 0 150 M 0 459 U/L Urine Amylase (spot) 0 150 F 0 459 U/L Urine Creatinine (spot) 0 150 M 8.0 16.0 mmol/l Urine Creatinine (spot) 0 150 F 8.0 16.0 mmol/l NOTE 1: Reference range is normally charted in SydPath reports as <X. However, where EDI is required for specific clinical trials, then it is primed in the SydPath test database as 0-X. NOTE: * Reference range for some analytes is from 0, however the limits of detection of some of these assays may not reach zero. In such instances, SydPath reports as <Limit of Detection (eg for ALT, reference range is from 0-30 U/L. Sydpath reports down to 5, and then <5). Excludes Paediatric Range LOC:3 Auth: Contract Pathology Manager Effective Date: 5th March 2010 Page 7 of 12

ANALYTE / SEX PHASE REFERENCE REFERENCE SI UNITS REVISION TEST LOW HIGH DATE Human Chorionic Gonadotrophin (hcg) - serum/plasma F Pre-menopausal <10 IU/L F Post-menopausal <10 IU/L F Preg - negative <10 IU/L F Preg - borderline 10 25 IU/L F Preg - positive >25 IU/L M <10 IU/L Luteinising Hormone (LH): F Follicular 2.4 13.0 IU/L 8/10/2009 F Mid cycle 14.0 97.0 IU/L 8/10/2009 F Luteal 1.0 12.0 IU/L 8/10/2009 F Post Menopausal 7.7 60.0 IU/L 8/10/2009 M Adult 1.7 8.6 IU/L 8/10/2009 M/F Child <2.0 IU/L Oestradiol (E2) F Follicular 75 750 pmol/l F Mid cycle 500 1500 pmol/l F Luteal 150 600 pmol/l F Post menopausal <100 pmol/l F Preg - 1st Trim <11 nmol/l F Preg - 2nd Trim 8 20 nmol/l F Preg - 3rd Trim 11 130 nmol/l M Adult 50 150 pmol/l Testosterone (TESTO) F Adult <3.0 nmol/l M Adult 12.0 36.0 nmol/l M Early Puberty 3.0 12.0 nmol/l M/F Child <3.0 nmol/l Follicle Stimulating Hormone (FSH): F Follicular 3.5 13.0 IU/L 8/10/2009 F Mid cycle 4.7 22.0 IU/L 8/10/2009 F Luteal 1.7 7.7 IU/L 8/10/2009 F Post Menopausal 25.0 140.0 IU/L 8/10/2009 M Adult 1.5 13.0 IU/L 8/10/2009 Progesterone: F Follicular 0.0 5.0 nmol/l F Luteal >15.0 nmol/l F Pregnancy 30.0 120 nmol/l M Adult 0.0 3.0 nmol/l LOC:3 Auth: Contract Pathology Manager Effective Date: 5th March 2010 Page 8 of 12

ANALYTE / AGE SEX NORMAL RESULT CUT/OFF SI UNITS REVISION TEST DATE Urine Drug Screens Amphetamines All Ages M/F Negative 300 ug/l Barbituates All Ages M/F Negative 200 ug/l Benzodiazepines All Ages M/F Negative 200 ug/l Cannabinoids All Ages M/F Negative 50 ug/l Cocaine All Ages M/F Negative 300 ug/l Methadone All Ages M/F Negative 300 ug/l Methaqualone All Ages M/F Negative 300 ug/l Opiates All Ages M/F Negative 300 ug/l Phencyclidine All Ages M/F Negative 25 ug/l Propoxyphene All Ages M/F Negative 300 ug/l TCA-tricylics All Ages M/F Negative 300 ug/l LOC:3 Auth: Contract Pathology Manager Effective Date: 5th March 2010 Page 9 of 12

IMMUNOLOGY A-1 Antitrypsin 0 150 M 0.9 2.0 g/l A-1 Antitrypsin 0 150 F 0.9 2.0 g/l Beta2 Microglob 0 150 M <2.4 mg/l Beta2 Microglob 0 150 F <2.4 mg/l C3 0 150 M 0.8 1.8 g/l C3 0 150 F 0.8 1.8 g/l CD3+ % 0 150 M 59 83 % CD3+ % 0 150 F 59 83 % CD3+ Count 0 150 M 780 2600 10^6/L CD3+ Count 0 150 F 780 2600 10^6/L CD4:CD8 Ratio 0 150 M 1.4 3.7 CD4:CD8 Ratio 0 150 F 1.4 3.7 CD4+ % 0 150 M 30 57 % CD4+ % 0 150 F 30 57 % CD4+ Count 0 150 M 500 1650 10^6/L CD4+ Count 0 150 F 500 1650 10^6/L CD8+ % 0 150 M 14 35 % CD8+ % 0 150 F 14 35 % CD8+ Count 0 150 M 210 1000 10^6/L CD8+ Count 0 150 F 210 1000 10^6/L dsdna 0 150 M <7 IU/mL dsdna 0 150 F <7 IU/mL Haptoglobin 0 150 M 0.3 2.0 g/l Haptoglobin 0 150 F 0.3 2.0 g/l IgG 0 3 months M/F 2.6 7.3 g/l IgG 3 months 6 months M/F 2.0 10.8 g/l IgG 6 months 2 years M/F 2.7 14.7 g/l IgG 2 3 M/F 2.5 13.3 g/l IgG 3 4 M/F 4.0 12.2 g/l IgG 4 6 M/F 5.5 15.4 g/l IgG 6 9 M/F 5.5 14.8 g/l IgG 9 12 M/F 7.5 14.0 g/l IgG 12 16 M/F 7.0 10.5 g/l IgG 16 150 M/F 6.7 14.4 g/l Rheumatoid Factor 0 150 M <9 IU/mL 01/07/08 Rheumatoid Factor 0 150 F <9 IU/mL 01/07/08 Total T cells 0 150 M 780 2600 10^6/L Total T cells 0 150 F 780 2600 10^6/L LOC:3 Auth: Contract Pathology Manager Effective Date: 5th March 2010 Page 10 of 12

ANALYTE / AGE SEX NORMAL REVISION TEST RESPONSE DATE SEROLOGY Hepatitis B Surface Antigen All Ages M/F Non Reactive (NR) Hepatitis C Antibodies All Ages M/F Non Reactive (NR) HIV Antibody/Antigen All Ages M/F Non Reactive (NR) Syphilis CMIA Total Antibody All Ages M/F Non Reactive (NR) Rubella IgG CMIA All Ages M/F 0.0-4.9 IU/mL = Negative 5.0-9.9 IU/mL = Equivocal 10.0-500.0 IU/mL = Positive HTLV I & II All Ages M/F Negative added 19/03/08 ANALYTE / AGE SEX NORMAL ABNORMAL ANALYTICAL RANGE REVISION TEST RESPONSE RESPONSE DATE MOLECULAR DIAGNOSTICS COBAS Amplicor HIV-1 VL All Ages M/F Not Detected Detected 40-10,000,000 copies 01/09/08 LOC:3 Auth: Contract Pathology Manager Effective Date: 5th March 2010 Page 11 of 12

ANALYTE / AGE SEX REFERENCE SI UNITS REVISION TEST RANGE DATE URINALYSIS Blood All Ages M/F Negative Glucose All Ages M/F Negative Ketones All Ages M/F Negative Leucocyte Esterase All Ages M/F Negative Nitrite All Ages M/F Negative ph All Ages M/F 5.0-8.0 Specific Gravity All Ages M/F 1.003-1.030 Bilirubin All Ages M/F Negative Protein All Ages M/F Negative Urobilinogen All Ages M/F Negative MICROSCOPY White Cells (WBC) All Ages M/F <10 10^6/L Red Cells (RBC) All Ages M/F <10 10^6/L Squamous Epithelial Cells All Ages M/F Nil 10^6/L Non-squamous Epithelial Cells All Ages M/F Nil 10^6/L Hyaline Casts All Ages M/F Nil N/A Granular Casts All Ages M/F Nil N/A Cellular Casts All Ages M/F Nil N/A Crystals All Ages M/F Nil N/A Bacteria All Ages M/F None Seen N/A Yeast All Ages M/F None Seen N/A LOC:3 Auth: Contract Pathology Manager Effective Date: 5th March 2010 Page 12 of 12