Global Measles and Rubella Update. April 2018

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Transcription:

Global Measles and Rubella Update April 218

Measles

Number of Reported Measles by WHO Regions 218 Region Member States* Suspected cases Measles cases Clin Epi Lab Jan Feb Mar Apr May Jun Jul Aug Sep Oct Nov Dec Date Received AFR 38/47 197 7361 5645 623 193 282 383 1476 218-4 AMR 26/35 265 376 376 3 9 364 218-4 EMR 15/21 3173 155 79 53 923 824 211 2 218-4 EUR 49/53 9172 8449 4265 263 3921 5476 2851 122 218-4 SEAR 1/11 1328 8733 7372 921 44 5195 3417 121 218-4 WPR 25/27 5425 215 1269 1 88 1485 665 218-4 Total 163/194 426 28124 1863 1861 7633 15785 1236 213 217 Region Member States* Suspected cases Measles cases Clin Epi Lab Jan Feb Mar Apr May Jun Jul Aug Sep Oct Nov Dec Date Received AFR 43/47 51541 24814 1992 8836 4986 321 2896 3642 237 226 1859 1475 1412 1519 1695 1315 1395 218-4 AMR 31/35 9997 895 895 2 1 19 13 5 1 4 36 85 116 62 542 218-4 EMR 2/21 3364 11392 936 693 9763 176 947 965 1578 1724 942 819 532 435 719 771 884 218-4 EUR 52/53 28851 2236 4844 5145 12371 115 1874 39 2883 2832 1555 1382 868 819 116 2111 2762 218-4 SEAR 11/11 97269 75377 5639 13216 5771 8683 979 13116 1324 7528 4384 3628 427 3389 29 3827 3619 218-4 WPR 26/27 5229 1518 2975 11 7442 785 899 159 1228 1129 833 776 717 741 78 629 492 218-4 Total 183/194 273552 145356 76137 27991 41228 14861 16335 2226 18396 15244 9574 884 7835 6988 737 8715 9694 Notes: Based on data received 218-4 - This is surveillance data, hence for the last month, the data may be incomplete. * Member States Reporting / Total Member States in Region

214-1 214-2 214-3 214-4 214-5 214-6 214-7 214-8 214-9 214-1 214-11 214-12 215-1 215-2 215-3 215-4 215-5 215-6 215-7 215-8 215-9 215-1 215-11 215-12 216-1 216-2 216-3 216-4 216-5 216-6 216-7 216-8 216-9 216-1 216-11 216-12 217-1 217-2 217-3 217-4 217-5 217-6 217-7 217-8 217-9 217-1 217-11 217-12 218-1 218-2 218-3 218-4 Measles cases (Lab+Epi+Clinical) Measles case distribution by month and WHO Region (214-218) 4 35 3 WPR SEAR EUR EMR AMR AFR 25 2 15 1 5 Notes: Based on data received 218-4 - Data Source: IVB Database - This is surveillance data, hence for the last month(s), the data may be incomplete.

Measles Incidence Rate per Million (12M period) Top 1** Country Rate India 51626 38.99 Nigeria 1391 55.87 Indonesia 779 29.83 Ukraine 7758 174.58 Pakistan 6151 31.84 China 5492 3.91 Italy 541 84.82 Romania 4474 226.21 Bangladesh 3225 19.79 Serbia 2827 32.52 Other countries with high incidence rates*** Country Rate Liberia 141 225.63 Gabon 394 199.1 Greece 1851 165.51 Georgia 379 96.55 Malaysia 2227 71.41 Tajikistan 539 61.71 Measles cases from countries with known discrepancies between case-based and aggregate surveillance, as reported by country Country Year Data Source DR Congo 217 45,165 218 5143 SITUATION EPIDEMIOLOGIQUE DE LA ROUGEOLE EN RDC, Week of 27/3/218 Somalia 217 23,353 218 4294 Somali EPI/POL Weekly Update Week 14, 218 Notes: Based on data received 218-4 and covering the period between 217-3 and 218-2 - Incidence: / population* * 1, - * World population prospects, 217 revision - ** Countries with the highest number of cases for the period - *** Countries with the highest incidence rates (excluding those already listed in the table above)

Number of Reported Measles (6M period) Top 1* Country India 18515 Ukraine 6184 Nigeria 3157 Serbia 2822 Pakistan 248 Indonesia 1959 Greece 174 Philippines 1684 China 1567 Malaysia 1167 Notes: Based on data received 218-4 - Surveillance data from 217-9 to 218-2 - * Countries with highest number of cases for the period

214-1 214-2 214-3 214-4 214-5 214-6 214-7 214-8 214-9 214-1 214-11 214-12 215-1 215-2 215-3 215-4 215-5 215-6 215-7 215-8 215-9 215-1 215-11 215-12 216-1 216-2 216-3 216-4 216-5 216-6 216-7 216-8 216-9 216-1 216-11 216-12 217-1 217-2 217-3 217-4 217-5 217-6 217-7 217-8 217-9 217-1 217-11 217-12 218-1 218-2 218-3 218-4 Number of measles cases Measles case distribution (AFR), 214-218 8 Uganda Others Nigeria Niger Liberia Gabon Ethiopia Equatorial Guinea DR Congo Cameroon Angola 6 4 2 Notes: Based on data received 218-4 - Data Source: IVB Database DRC has experienced a nationwide epidemic that has affected all Provinces, however, only a small proportion of the measles cases in the IDSR aggregate reporting system are reflected in the case based data. As of 27 May 213, South Sudan has reassigned to the Africa region (AFR) from the Eastern Mediterranean region (EMR). For data presentation and statistical purposes, South Sudan data is presented in AFR for all the

Incidence rate per 1,, 216-3 216-4 216-5 216-6 216-7 216-8 216-9 216-1 216-11 216-12 217-1 217-2 217-3 217-4 217-5 217-6 217-7 217-8 217-9 217-1 217-11 217-12 218-1 218-2 218-3 218-4 Measles cases: Benin 2 1 Discarded Clinical Epi Lab 25 2 15 1 5 Benin age distribution, vaccination status, and incidence, 217-3 to 218-2 148.7 77.3 64.3 23.6 12 4.2 1 <1 year 1-4 years 5-9 years 1-14 years 15-24 years 25-39 years 4+ years Age at onset doses 1 dose 2+ doses Unknown 15 1 5 Year Confirmed 26 223 27 351 28 68 29 914 21 246 211 423 212 285 213 757 214 761 215 53 216 98 217 192 218 272

Incidence rate per 1,, 216-3 216-4 216-5 216-6 216-7 216-8 216-9 216-1 216-11 216-12 217-1 217-2 217-3 217-4 217-5 217-6 217-7 217-8 217-9 217-1 217-11 217-12 218-1 218-2 218-3 218-4 Measles cases: Democratic Republic of the Congo 4 Rollover-Nat (6-59 M) Cov: 12% Sub-national (6-59 M) Cov: 13.5% 3 2 1 Sub-national (6-59 M) Cov: 99.5% Discarded Clinical Epi Lab National SIA Sub-national SIA Democratic Republic of the Congo age distribution, vaccination status, and incidence, 217-3 to 218-2 15 148.6 121.8 15 1 1 5 35.4 5 1.7 6.4 3.3.4 <1 year 1-4 years 5-9 years 1-14 years 15-24 years 25-39 years 4+ years Age at onset doses 1 dose 2+ doses Unknown Year Confirmed 26 112 27 539 28 214 29 83 21 28 211 1651 212 2332 213 2527 214 1649 215 529 216 4932 217 3597 218 44

Incidence rate per 1,, 216-3 216-4 216-5 216-6 216-7 216-8 216-9 216-1 216-11 216-12 217-1 217-2 217-3 217-4 217-5 217-6 217-7 217-8 217-9 217-1 217-11 217-12 218-1 218-2 218-3 218-4 Measles cases: Ethiopia 1 Sub-national (6 M-<15 Y) Cov: 97% Sub-national (9 M-14 Y) Cov: 96.3% Sub-national (6-179 M) Cov: 98% 8 6 4 2 Discarded Clinical Epi Lab National SIA Sub-national SIA 6 5 4 3 2 1 Ethiopia age distribution, vaccination status, and incidence, 217-3 to 218-2 29.6 24.8 25.3 21.2 14.8 9.5.6 <1 year 1-4 years 5-9 years 1-14 years 15-24 years 25-39 years 4+ years Age at onset doses 1 dose 2+ doses Unknown 3 2 1 Year Confirmed 26 1278 27 1472 28 3161 29 2642 21 625 211 3552 212 4616 213 6137 214 14282 215 17778 216 4568 217 1912 218 324

Incidence rate per 1,, 216-3 216-4 216-5 216-6 216-7 216-8 216-9 216-1 216-11 216-12 217-1 217-2 217-3 217-4 217-5 217-6 217-7 217-8 217-9 217-1 217-11 217-12 218-1 218-2 218-3 218-4 Measles cases: Guinea Extent unknown (6-59 M) 3 2 1 Discarded Clinical Epi Lab National SIA Sub-national SIA 3 25 2 15 1 5 Guinea age distribution, vaccination status, and incidence, 217-3 to 218-2 157.7 18.1 47.5 12.9 4.8 2.1 <1 year 1-4 years 5-9 years 1-14 years 15-24 years 25-39 years 4+ years Age at onset doses 1 dose 2+ doses Unknown 15 1 5 Year Confirmed 26 2 27 6 28 92 29 216 21 58 211 2 212 14 213 59 214 216 215 29 216 334 217 596 218 22

Incidence rate per 1,, 216-3 216-4 216-5 216-6 216-7 216-8 216-9 216-1 216-11 216-12 217-1 217-2 217-3 217-4 217-5 217-6 217-7 217-8 217-9 217-1 217-11 217-12 218-1 218-2 218-3 218-4 Measles cases: Liberia 6 5 4 3 2 1 National (9-59 M) Discarded Clinical Epi Lab National SIA Sub-national SIA 4 3 2 1 Liberia age distribution, vaccination status, and incidence, 217-3 to 218-2 713.5 566.5 236.4 121 38.9 8.4 <1 year 1-4 years 5-9 years 1-14 years 15-24 years 25-39 years 4+ years Age at onset doses 1 dose 2+ doses Unknown 8 6 4 2 Year Confirmed 26 27 1 28 1 29 1 21 11 211 24 212 4 213 214 215 436 216 4 217 392 218 892

Incidence rate per 1,, 216-3 216-4 216-5 216-6 216-7 216-8 216-9 216-1 216-11 216-12 217-1 217-2 217-3 217-4 217-5 217-6 217-7 217-8 217-9 217-1 217-11 217-12 218-1 218-2 218-3 218-4 Measles cases: Mali 3 2 1 Discarded Clinical Epi Lab 6 5 4 3 2 1 Mali age distribution, vaccination status, and incidence, 217-3 to 218-2 31.5 19.8 7.5 4.8 3.5 3.4.4 <1 year 1-4 years 5-9 years 1-14 years 15-24 years 25-39 years 4+ years Age at onset doses 1 dose 2+ doses Unknown 3 2 1 Year Confirmed 26 126 27 2 28 96 29 2929 21 1712 211 26 212 366 213 36 214 281 215 232 216 19 217 21 218 213

Incidence rate per 1,, 216-3 216-4 216-5 216-6 216-7 216-8 216-9 216-1 216-11 216-12 217-1 217-2 217-3 217-4 217-5 217-6 217-7 217-8 217-9 217-1 217-11 217-12 218-1 218-2 218-3 218-4 Measles cases: Niger 3 2 1 Discarded Clinical Epi Lab 25 2 15 1 5 Niger age distribution, vaccination status, and incidence, 217-3 to 218-2 68.4 62.4 29.9 19.9 12.7 8.3 1.3 <1 year 1-4 years 5-9 years 1-14 years 15-24 years 25-39 years 4+ years Age at onset doses 1 dose 2+ doses Unknown 8 6 4 2 Year Confirmed 26 49 27 276 28 1233 29 797 21 38 211 771 212 311 213 786 214 376 215 756 216 77 217 392 218 336

Incidence rate per 1,, 216-3 216-4 216-5 216-6 216-7 216-8 216-9 216-1 216-11 216-12 217-1 217-2 217-3 217-4 217-5 217-6 217-7 217-8 217-9 217-1 217-11 217-12 218-1 218-2 218-3 218-4 Measles cases: Nigeria 4 3 2 1 Sub-national (6 M-1 Y) Extent unknown (9-59 M) Discarded Clinical Epi Lab National SIA Sub-national SIA 6 4 2 Nigeria age distribution, vaccination status, and incidence, 217-3 to 218-2 236.3 13.2 83.1 27.2 12.3 9.8 4.8 <1 year 1-4 years 5-9 years 1-14 years 15-24 years 25-39 years 4+ years Age at onset doses 1 dose 2+ doses Unknown 25 2 15 1 5 Year Confirmed 26 119 27 3129 28 1453 29 1498 21 972 211 1962 212 6423 213 55392 214 685 215 12391 216 17581 217 11188 218 197

Incidence rate per 1,, 216-3 216-4 216-5 216-6 216-7 216-8 216-9 216-1 216-11 216-12 217-1 217-2 217-3 217-4 217-5 217-6 217-7 217-8 217-9 217-1 217-11 217-12 218-1 218-2 218-3 218-4 Measles cases: Uganda 3 2 1 Discarded Clinical Epi Lab 6 5 4 3 2 1 Uganda age distribution, vaccination status, and incidence, 217-3 to 218-2 12 97.4 41.6 18.2 3.8 1.7.4 <1 year 1-4 years 5-9 years 1-14 years 15-24 years 25-39 years 4+ years Age at onset doses 1 dose 2+ doses Unknown 12 1 8 6 4 2 Year Confirmed 26 135 27 291 28 115 29 86 21 41 211 132 212 72 213 46 214 315 215 466 216 252 217 892 218 248

214-1 214-2 214-3 214-4 214-5 214-6 214-7 214-8 214-9 214-1 214-11 214-12 215-1 215-2 215-3 215-4 215-5 215-6 215-7 215-8 215-9 215-1 215-11 215-12 216-1 216-2 216-3 216-4 216-5 216-6 216-7 216-8 216-9 216-1 216-11 216-12 217-1 217-2 217-3 217-4 217-5 217-6 217-7 217-8 217-9 217-1 217-11 217-12 218-1 218-2 218-3 Number of measles cases Measles case distribution (AMR), 214-218 12 11 1 9 Venezuela (Bolivarian Republic of) USA Peru Others Mexico Ecuador Colombia Chile Canada Brazil Argentina 8 7 6 5 4 3 2 1 Notes: Based on data received 218-4 - Data Source: IVB Database

Incidence rate per 1,, 216-3 216-4 216-5 216-6 216-7 216-8 216-9 216-1 216-11 216-12 217-1 217-2 217-3 217-4 217-5 217-6 217-7 217-8 217-9 217-1 217-11 217-12 218-1 218-2 218-3 218-4 Measles cases: Venezuela (Bolivarian Republic of) Note: Given the current outbreaks in the country, data reporting delays are occurring. Data shown here are a combination of aggregate data for the epicurve and case-based data for the age/vaccination status, which are currently not entirely up to date. Additionally, the large numbers of cases in December 217 and March 218 (with none in January-February) are reporting artifacts. 5 4 3 2 1 Discarded Clinical Epi Lab 15 1 5 Venezuela (Bolivarian Republic of) age distribution, vaccination status, and incidence, 217-3 to 218-2 148.7 53.6 2.2 21.7 <1 year 1-4 years 5-9 years 1-14 years 15-24 years 25-39 years 4+ years Age at onset 4 1.5.9 doses 1 dose 2+ doses Unknown 15 1 5 Year Confirmed 28 29 21 211 212 1 213 214 215 216 217 727 218 279

214-1 214-2 214-3 214-4 214-5 214-6 214-7 214-8 214-9 214-1 214-11 214-12 215-1 215-2 215-3 215-4 215-5 215-6 215-7 215-8 215-9 215-1 215-11 215-12 216-1 216-2 216-3 216-4 216-5 216-6 216-7 216-8 216-9 216-1 216-11 216-12 217-1 217-2 217-3 217-4 217-5 217-6 217-7 217-8 217-9 217-1 217-11 217-12 218-1 218-2 218-3 Number of measles cases Measles case distribution (EMR), 214-218 3 25 Yemen United Arab Emirates Syrian Arab Republic Sudan Somalia Pakistan Others Iraq Iran (Islamic Republic of) Egypt Afghanistan 2 15 1 5 Notes: Based on data received 218-4 - Data Source: IVB Database

Incidence rate per 1,, 216-3 216-4 216-5 216-6 216-7 216-8 216-9 216-1 216-11 216-12 217-1 217-2 217-3 217-4 217-5 217-6 217-7 217-8 217-9 217-1 217-11 217-12 218-1 218-2 218-3 218-4 Measles cases: Pakistan 2 1 Discarded Clinical Epi Lab 4 2 Pakistan age distribution, vaccination status, and incidence, 217-3 to 218-2 295.4 172.7 41.2 8.5 1.2.6.1 <1 year 1-4 years 5-9 years 1-14 years 15-24 years 25-39 years 4+ years Age at onset doses 1 dose 2+ doses Unknown 3 2 1 Year Confirmed 26 35 27 33 28 53 29 472 21 1111 211 2676 212 848 213 83 214 137 215 1117 216 286 217 6631 218 367

Incidence rate per 1,, 216-3 216-4 216-5 216-6 216-7 216-8 216-9 216-1 216-11 216-12 217-1 217-2 217-3 217-4 217-5 217-6 217-7 217-8 217-9 217-1 217-11 217-12 218-1 218-2 218-3 218-4 Measles cases: Syrian Arab Republic 2 1 Discarded Clinical Epi Lab 25 2 15 1 5 Syrian Arab Republic age distribution, vaccination status, and incidence, 217-3 to 218-2 334.5 123.8 7.5 48.4 13.5 13.2 1.7 <1 year 1-4 years 5-9 years 1-14 years 15-24 years 25-39 years 4+ years Age at onset doses 1 dose 2+ doses Unknown 4 3 2 1 Year Confirmed 26 471 27 38 28 1 29 36 21 9 211 2 212 13 213 42 214 594 215 45 216 66 217 738 218 113

214-1 214-2 214-3 214-4 214-5 214-6 214-7 214-8 214-9 214-1 214-11 214-12 215-1 215-2 215-3 215-4 215-5 215-6 215-7 215-8 215-9 215-1 215-11 215-12 216-1 216-2 216-3 216-4 216-5 216-6 216-7 216-8 216-9 216-1 216-11 216-12 217-1 217-2 217-3 217-4 217-5 217-6 217-7 217-8 217-9 217-1 217-11 217-12 218-1 218-2 218-3 Number of measles cases Measles case distribution (EUR), 214-218 6 Ukraine Serbia Russian Federation Romania Others Kyrgyzstan Kazakhstan Italy Germany Georgia Bosnia and Herzegovina 5 4 3 2 1 Notes: Based on data received 218-4 - Data Source: IVB Database

Incidence rate per 1,, 216-3 216-4 216-5 216-6 216-7 216-8 216-9 216-1 216-11 216-12 217-1 217-2 217-3 217-4 217-5 217-6 217-7 217-8 217-9 217-1 217-11 217-12 218-1 218-2 218-3 218-4 Measles cases: France 6 5 4 3 2 1 Discarded Clinical Epi Lab 3 2 1 France age distribution, vaccination status, and incidence, 217-3 to 218-2 12.5 8.4 39.3 22.3 26.6 23.3 2 <1 year 1-4 years 5-9 years 1-14 years 15-24 years 25-39 years 4+ years Age at onset doses 1 dose 2+ doses Unknown 14 12 1 8 6 4 2 Year Confirmed 26 16 27 4 28 66 29 1541 21 519 211 15214 212 859 213 272 214 267 215 373 216 79 217 52 218 745

Incidence rate per 1,, 216-3 216-4 216-5 216-6 216-7 216-8 216-9 216-1 216-11 216-12 217-1 217-2 217-3 217-4 217-5 217-6 217-7 217-8 217-9 217-1 217-11 217-12 218-1 218-2 218-3 218-4 Measles cases: Georgia 3 2 1 Discarded Clinical Epi Lab 14 12 1 8 6 4 2 Georgia age distribution, vaccination status, and incidence, 217-3 to 218-2 1181.5 298 157.5 231.8 84.2 127.2 4.8 <1 year 1-4 years 5-9 years 1-14 years 15-24 years 25-39 years 4+ years Age at onset doses 1 dose 2+ doses Unknown 14 12 1 8 6 4 2 Year Confirmed 26 8 27 2 28 55 29 23 21 22 211 64 212 3 213 7868 214 319 215 43 216 14 217 96 218 283

Incidence rate per 1,, 216-3 216-4 216-5 216-6 216-7 216-8 216-9 216-1 216-11 216-12 217-1 217-2 217-3 217-4 217-5 217-6 217-7 217-8 217-9 217-1 217-11 217-12 218-1 218-2 218-3 218-4 Measles cases: Greece 5 4 3 2 1 Discarded Clinical Epi Lab 6 5 4 3 2 1 Greece age distribution, vaccination status, and incidence, 217-3 to 218-2 223.4 1214.9 679.3 343.9 139.3 118.2 25 <1 year 1-4 years 5-9 years 1-14 years 15-24 years 25-39 years 4+ years Age at onset doses 1 dose 2+ doses Unknown 25 2 15 1 5 Year Confirmed 26 215 27 1 28 1 29 2 21 149 211 4 212 3 213 2 214 1 215 1 216 217 164 218 787

Incidence rate per 1,, 216-3 216-4 216-5 216-6 216-7 216-8 216-9 216-1 216-11 216-12 217-1 217-2 217-3 217-4 217-5 217-6 217-7 217-8 217-9 217-1 217-11 217-12 218-1 218-2 218-3 218-4 Measles cases: Italy 12 1 8 6 4 2 Discarded Clinical Epi Lab 2 15 1 5 Italy age distribution, vaccination status, and incidence, 217-3 to 218-2 622 283.5 154.2 19.1 88.4 65.5 23.7 <1 year 1-4 years 5-9 years 1-14 years 15-24 years 25-39 years 4+ years Age at onset doses 1 dose 2+ doses Unknown 6 4 2 Year Confirmed 26 222 27 76 28 1619 29 173 21 861 211 5189 212 67 213 2256 214 3286 215 265 216 862 217 541 218 411

Incidence rate per 1,, 216-3 216-4 216-5 216-6 216-7 216-8 216-9 216-1 216-11 216-12 217-1 217-2 217-3 217-4 217-5 217-6 217-7 217-8 217-9 217-1 217-11 217-12 218-1 218-2 218-3 218-4 Measles cases: Russian Federation 4 3 2 1 Discarded Clinical Epi Lab 5 4 3 2 1 Russian Federation age distribution, vaccination status, and incidence, 217-3 to 218-2 93.4 57.8 14.5 7.2 6.9 6.6 1.4 <1 year 1-4 years 5-9 years 1-14 years 15-24 years 25-39 years 4+ years Age at onset doses 1 dose 2+ doses Unknown 1 8 6 4 2 Year Confirmed 26 1129 27 172 28 27 29 11 21 152 211 783 212 1975 213 251 214 3263 215 635 216 179 217 868 218 41

Incidence rate per 1,, 216-3 216-4 216-5 216-6 216-7 216-8 216-9 216-1 216-11 216-12 217-1 217-2 217-3 217-4 217-5 217-6 217-7 217-8 217-9 217-1 217-11 217-12 218-1 218-2 218-3 218-4 Measles cases: Serbia 14 12 1 8 6 4 2 Discarded Clinical Epi Lab 15 1 5 Serbia age distribution, vaccination status, and incidence, 217-3 to 218-2 2991.3 1467.1 34.8 176.1 93 185.3 298.1 <1 year 1-4 years 5-9 years 1-14 years 15-19 years 2-29 years 3+ years Age at onset doses 1 dose 2+ doses Unknown 3 2 1 Year Confirmed 26 27 147 28 2 29 1 21 8 211 358 212 213 1 214 35 215 368 216 14 217 72 218 2131

Incidence rate per 1,, 216-3 216-4 216-5 216-6 216-7 216-8 216-9 216-1 216-11 216-12 217-1 217-2 217-3 217-4 217-5 217-6 217-7 217-8 217-9 217-1 217-11 217-12 218-1 218-2 218-3 218-4 Measles cases: Ukraine 3 2 1 Discarded Clinical Epi Lab 2 15 1 5 Ukraine age distribution, vaccination status, and incidence, 217-3 to 218-2 19.9 937.1 721.6 452.9 163 91.8 48 <1 year 1-4 years 5-9 years 1-14 years 15-19 years 2-29 years 3+ years Age at onset doses 1 dose 2+ doses Unknown 12 1 8 6 4 2 Year Confirmed 26 945 27 232 28 41 29 24 21 42 211 1313 212 12744 213 338 214 2326 215 141 216 9 217 4767 218 33

214-1 214-2 214-3 214-4 214-5 214-6 214-7 214-8 214-9 214-1 214-11 214-12 215-1 215-2 215-3 215-4 215-5 215-6 215-7 215-8 215-9 215-1 215-11 215-12 216-1 216-2 216-3 216-4 216-5 216-6 216-7 216-8 216-9 216-1 216-11 216-12 217-1 217-2 217-3 217-4 217-5 217-6 217-7 217-8 217-9 217-1 217-11 217-12 218-1 218-2 218-3 Number of measles cases Measles case distribution (SEAR (excl. India)), 214-218 35 3 Timor-Leste Thailand Sri Lanka Nepal Myanmar Maldives Indonesia DPR Korea Bhutan Bangladesh 25 2 15 1 5 Notes: Based on data received 218-4 - Data Source: IVB Database

Incidence rate per 1,, 216-3 216-4 216-5 216-6 216-7 216-8 216-9 216-1 216-11 216-12 217-1 217-2 217-3 217-4 217-5 217-6 217-7 217-8 217-9 217-1 217-11 217-12 218-1 218-2 218-3 218-4 Measles cases: Indonesia 6 Sub-national (9-59 M) Cov: 86% Sub-national (9 M-15 Y) Cov: 1.5% 4 2 Discarded Clinical Epi Lab National SIA Sub-national SIA 12 1 8 6 4 2 Indonesia age distribution, vaccination status, and incidence, 217-3 to 218-2 47.2 48.5 35.4 21.4 9.9 3.1 <1 year 1-4 years 5-9 years 1-14 years 15-24 years 25-39 years 4+ years Age at onset doses 1 dose 2+ doses Unknown 4 2 Year Confirmed 26 21911 27 2837 28 16417 29 218 21 23471 211 2351 212 16786 213 193 214 9498 215 629 216 724 217 11389 218 254

214-1 214-2 214-3 214-4 214-5 214-6 214-7 214-8 214-9 214-1 214-11 214-12 215-1 215-2 215-3 215-4 215-5 215-6 215-7 215-8 215-9 215-1 215-11 215-12 216-1 216-2 216-3 216-4 216-5 216-6 216-7 216-8 216-9 216-1 216-11 216-12 217-1 217-2 217-3 217-4 217-5 217-6 217-7 217-8 217-9 217-1 217-11 217-12 218-1 218-2 Number of measles cases Measles case distribution (SEAR, India), 214-218 15 India 1 5 Notes: Based on data received 218-4 - Data Source: IVB Database

Incidence rate per 1,, 216-3 216-4 216-5 216-6 216-7 216-8 216-9 216-1 216-11 216-12 217-1 217-2 217-3 217-4 217-5 217-6 217-7 217-8 217-9 217-1 217-11 217-12 218-1 218-2 218-3 218-4 Measles cases: India 4 Rollover-Nat (9 M-15 Y) 3 2 1 Discarded Clinical Epi Lab National SIA Sub-national SIA 6 4 5.1 India age distribution, vaccination status, and incidence, 217-3 to 218-2 59.8 48.7 6 4 Year Confirmed 214 836 215 8326 216 7798 217 5632 218 7645 2 13.8 2 <1 year 1-4 years 5-9 years 1-14 years 15-24 years 25-39 years 4+ years Age at onset 2.1.5.1 doses 1 dose 2+ doses Unknown

214-1 214-2 214-3 214-4 214-5 214-6 214-7 214-8 214-9 214-1 214-11 214-12 215-1 215-2 215-3 215-4 215-5 215-6 215-7 215-8 215-9 215-1 215-11 215-12 216-1 216-2 216-3 216-4 216-5 216-6 216-7 216-8 216-9 216-1 216-11 216-12 217-1 217-2 217-3 217-4 217-5 217-6 217-7 217-8 217-9 217-1 217-11 217-12 218-1 218-2 Number of measles cases Measles case distribution (WPR), 214-218 22 2 18 16 14 12 1 8 6 4 2 Viet Nam Singapore Republic of Korea Philippines Papua New Guinea Others Mongolia Malaysia Japan China Australia Notes: Based on data received 218-4 - Data Source: IVB Database

Incidence rate per 1,, 216-3 216-4 216-5 216-6 216-7 216-8 216-9 216-1 216-11 216-12 217-1 217-2 217-3 217-4 217-5 217-6 217-7 217-8 217-9 217-1 217-11 217-12 218-1 218-2 218-3 218-4 Measles cases: Philippines 1 8 6 4 2 Discarded Clinical Epi Lab 1 8 6 4 2 Philippines age distribution, vaccination status, and incidence, 217-3 to 218-2 279.5 91.7 18.2 9 15.7 9 1.8 <1 year 1-4 years 5-9 years 1-14 years 15-24 years 25-39 years 4+ years Age at onset doses 1 dose 2+ doses Unknown 3 25 2 15 1 5 Year Confirmed 26 216 27 612 28 838 29 1351 21 6363 211 6519 212 1441 213 4855 214 5396 215 221 216 647 217 162 218 855

Distribution of measles genotypes (last 12 months) Notes: Data Source: MeaNS database (Genotypes) and IVB Database (Incidence) as of 218-4-16 and covering the period 217-3-1 to 218-2-28 - Pie charts proportional to the number of sequenced viruses

Rubella

Number of Reported Rubella by WHO Regions 218 Region Member States* Rubella cases Clin Epi Lab Jan Feb Mar Apr May Jun Jul Aug Sep Oct Nov Dec Date Received AFR 29/47 323 323 212 97 14 218-4 AMR 19/35 218-4 EMR 15/21 126 1 125 59 67 218-4 EUR 21/53 116 11 1 14 57 59 218-4 SEAR 9/11 329 2 327 186 13 13 218-4 WPR 9/27 152 27 7 118 99 53 218-4 Total 12/194 146 129 1 97 613 46 27 217 Region Member States* Rubella cases Clin Epi Lab Jan Feb Mar Apr May Jun Jul Aug Sep Oct Nov Dec Date Received AFR 42/47 4569 4569 278 515 586 328 343 372 212 331 388 647 459 11 218-4 AMR 26/35 218-4 EMR 2/21 897 43 1 853 7 111 17 114 175 18 42 19 22 45 46 38 218-4 EUR 3/53 724 588 18 118 63 61 89 71 85 59 55 47 39 6 49 46 218-4 SEAR 11/11 7538 2171 5367 583 199 1557 1225 799 356 319 57 339 358 243 153 218-4 WPR 13/27 2283 258 162 1863 153 21 342 38 295 194 195 129 115 81 18 162 218-4 Total 142/194 1611 889 2352 1277 1147 1987 2681 246 1697 189 823 133 93 1191 95 59 Notes: Based on data received 218-4 - This is surveillance data, hence for the last month, the data may be incomplete. * Member States Reporting / Total Member States in Region

215-1 215-2 215-3 215-4 215-5 215-6 215-7 215-8 215-9 215-1 215-11 215-12 216-1 216-2 216-3 216-4 216-5 216-6 216-7 216-8 216-9 216-1 216-11 216-12 217-1 217-2 217-3 217-4 217-5 217-6 217-7 217-8 217-9 217-1 217-11 217-12 218-1 218-2 218-3 Rubella cases (Lab+Epi+Clinical) Rubella Case Distribution by Month and WHO Region (215-218) 55 5 45 WPR SEAR EUR EMR AFR 4 35 3 25 2 15 1 5 Notes: Based on data received 218-4 - Data Source: IVB Database - This is surveillance data, hence for the last month(s), the data may be incomplete.

1 2 3 4 5 6 7 8 9 1 11 12 13 14 15 16 17 18 19 2 21 22 23 24 25 26 27 28 29 3 31 32 33 34 35 36 37 38 39 4 41 42 43 44 45 46 (IgM+ only) 216-3 216-4 216-5 216-6 216-7 216-8 216-9 216-1 216-11 216-12 217-1 217-2 217-3 217-4 217-5 217-6 217-7 217-8 217-9 217-1 217-11 217-12 218-1 218-2 218-3 218-4 (IgM+ only) Rubella cases: AFR AFR Rubella Case Distribution (April 216-March 218) 6 Top 1 countries (last 12 M) 4 label RCV in RI % of Total 2 South Africa No 153 43 DR Congo No 631 18 Others - 284 8 Ethiopia No 272 8 Uganda No 249 7 Not introduced in EPI Introduced <5 years ago (after 212) Introduced >=5 years ago (212 and before) Nigeria No 168 5 Cote d'ivoire No 161 5 Madagascar No 111 3 6 AFR Age distribution of Rubella IgM+ cases by vaccine introduction status in the National EPI Programme (April 217-March 218) Mozambique 217 51 1 Algeria 217 45 1 Sierra Leone 217 38 1 4 2 Age at onset (in years) Rubella vaccine not introduced before 1 January 217 Rubella vaccine introduced before 1 January 217 Notes: Based on data received 218-4 Data Source: IVB Database. RCV in RI: Rubella-containing vaccine in Routine Immunization as of 31 Dec 216.

Incidence rate per 1,, 216-4 216-5 216-6 216-7 216-8 216-9 216-1 216-11 216-12 217-1 217-2 217-3 217-4 217-5 217-6 217-7 217-8 217-9 217-1 217-11 217-12 218-1 218-2 218-3 218-4 Rubella cases: Algeria 15 1 5 Clinical Epi Lab 2 15 1 5 Algeria age distribution, vaccination status, and incidence, 217-3 to 218-2 5 2.7 2.1.6.1 <1 year 1-4 years 5-9 years 1-14 years 15-24 years 25-39 years 4+ years Age at onset 6 4 2 Year Confirmed 215 2 216 11 217 22 218 29 doses 1 dose 2+ doses Unknown

1 2 3 4 5 6 7 8 9 1 11 12 13 14 15 16 17 18 19 2 21 22 23 24 25 26 27 28 29 3 31 32 33 34 35 36 37 38 39 4 41 42 43 44 45 46 (lab + epi-linked + clinical) 216-3 216-4 216-5 216-6 216-7 216-8 216-9 216-1 216-11 216-12 217-1 217-2 217-3 217-4 217-5 217-6 217-7 217-8 217-9 217-1 217-11 217-12 218-1 218-2 218-3 218-4 (lab + epi-linked + clinical) Rubella cases: EMR 4 EMR Rubella Case Distribution (April 216-March 218) 3 Top 1 countries (last 12 M) 2 label RCV in RI % of Total 1 Pakistan No 365 5 Sudan No 187 25 Saudi Arabia 1991 3 4 Afghanistan No 29 4 Others - 26 4 Not introduced in EPI Introduced <5 years ago (after 212) Introduced >=5 years ago (212 and before) United Arab Emirates 1985 26 4 Egypt 1999 21 3 1 EMR Age distribution of Rubella cases by vaccine introduction status in the National EPI Programme (April 217-March 218) Iran (Islamic Republic of) 24 17 2 Yemen 215 14 2 8 Lebanon 1995 12 2 6 4 Tunisia 24 8 1 2 Age at onset (in years) Rubella vaccine not introduced before 1 January 217 Rubella vaccine introduced before 1 January 217 Notes: Based on data received 218-4 Data Source: IVB Database. RCV in RI: Rubella-containing vaccine in Routine Immunization as of 31 Dec 216.

(lab + epi-linked + clinical) (lab + epi-linked + clinical) 1 2 3 4 5 6 7 8 9 1 11 12 13 14 15 16 17 18 19 2 21 22 23 24 25 26 27 28 29 3 31 32 33 34 35 36 37 38 39 4 41 42 43 44 45 46 216-3 216-4 216-5 216-6 216-7 216-8 216-9 216-1 216-11 216-12 217-1 217-2 217-3 217-4 217-5 217-6 217-7 217-8 Notes: Based on data received 218-4 Data Source: IVB Database. RCV in RI: Rubella-containing vaccine in Routine Immunization as of 31 Dec 216. Spikes in age-distribution curve are an artifact of reporting by age bands ( =<1 yrs, 2=1-4 yrs, 7=5-9 yrs, 12=1-14 yrs, 17=15-19 yrs, 25=2-29 yrs, 45=3+yrs) instead of by age from some member states. 217-9 217-1 217-11 217-12 218-1 218-2 218-3 218-4 Rubella cases: EUR 2 EUR Rubella Case Distribution (April 216-March 218) 1 label Top 1 countries (last 12 M) RCV in RI % of Total Poland 1988 448 71 Germany 1991 64 1 Italy 1972 45 7 2 Not introduced in EPI Introduced <5 years ago (after 212) Introduced >=5 years ago (212 and before) EUR Age distribution of Rubella cases by vaccine introduction status in the National EPI Programme (April 217-March 218) Austria 1973 22 4 Others - 13 2 Georgia 24 11 2 Romania 22 8 1 Russian Federation 2 6 1 Kyrgyzstan 21 4 1 Turkey 26 3 1 United Kingdom of Great Britain and Northern Ireland 197 3 Age at onset (in years) Rubella vaccine not introduced before 1 January 217 Rubella vaccine introduced before 1 January 217

1 2 3 4 5 6 7 8 9 1 11 12 13 14 15 16 17 18 19 2 21 22 23 24 25 26 27 28 29 3 31 32 33 34 35 36 37 38 39 4 41 42 43 44 45 46 (lab + epi-linked + clinical) 216-3 216-4 216-5 216-6 216-7 216-8 216-9 216-1 216-11 216-12 217-1 217-2 217-3 217-4 217-5 217-6 217-7 217-8 217-9 217-1 217-11 217-12 218-1 218-2 218-3 218-4 (lab + epi-linked + clinical) Rubella cases: SEAR (excl. India) SEAR (excl. India) Rubella Case Distribution (April 216-March 218) 6 4 label Top 1 countries (last 12 M) RCV in RI % of Total 2 Indonesia No 394 91 Bangladesh 212 258 8 Nepal 213 18 1 Thailand 1993 16 Bhutan 26 4 Not introduced in EPI Introduced <5 years ago (after 212) Introduced >=5 years ago (212 and before) Timor-Leste 216 4 Myanmar 215 2 Sri Lanka 1996 1 3 2 1 SEAR (excl. India) Age distribution of Rubella cases by vaccine introduction status in the National EPI Programme (April 217-March 218) Age at onset (in years) Rubella vaccine not introduced before 1 January 217 Rubella vaccine introduced before 1 January 217 Notes: Based on data received 218-4 Data Source: IVB Database. RCV in RI: Rubella-containing vaccine in Routine Immunization as of 31 Dec 216.

1 2 3 4 5 6 7 8 9 1 11 12 13 14 15 16 17 18 19 2 21 22 23 24 25 26 27 28 29 3 31 32 33 34 35 36 37 38 39 4 41 42 43 44 45 46 (lab + epi-linked + clinical) 216-3 216-4 216-5 216-6 216-7 216-8 216-9 216-1 216-11 216-12 217-1 217-2 217-3 217-4 217-5 217-6 217-7 217-8 217-9 217-1 217-11 217-12 218-1 218-2 218-3 218-4 (lab + epi-linked + clinical) Rubella cases: SEAR, India 4 SEAR, India Rubella Case Distribution (April 216-March 218) 3 2 label Top 1 countries (last 12 M) RCV in RI % of Total 1 India No 1231 1 Not introduced in EPI Introduced <5 years ago (after 212) Introduced >=5 years ago (212 and before) 2 SEAR, India Age distribution of Rubella cases by vaccine introduction status in the National EPI Programme (April 217-March 218) 1 Age at onset (in years) Rubella vaccine not introduced before 1 January 217 Rubella vaccine introduced before 1 January 217 Notes: Based on data received 218-4 Data Source: IVB Database. RCV in RI: Rubella-containing vaccine in Routine Immunization as of 31 Dec 216.

1 2 3 4 5 6 7 8 9 1 11 12 13 14 15 16 17 18 19 2 21 22 23 24 25 26 27 28 29 3 31 32 33 34 35 36 37 38 39 4 41 42 43 44 45 46 (lab + epi-linked + clinical) 216-3 216-4 216-5 216-6 216-7 216-8 216-9 216-1 216-11 216-12 217-1 217-2 217-3 217-4 217-5 217-6 217-7 217-8 217-9 217-1 217-11 217-12 218-1 218-2 218-3 218-4 (lab + epi-linked + clinical) Rubella cases: WPR WPR Rubella Case Distribution (April 216-March 218) 2 1 label Top 1 countries (last 12 M) RCV in RI % of Total China 28 1273 73 Philippines 21 267 15 Malaysia 1998 1 6 Viet Nam 215 76 4 Mongolia 29 8 Not introduced in EPI Introduced <5 years ago (after 212) Introduced >=5 years ago (212 and before) Cambodia 213 3 Lao People's Democratic Republic 212 3 12 1 8 6 4 2 WPR (Excl. China) Age distribution of Rubella cases by vaccine introduction status in the National EPI Programme (April 217-March 218) Singapore 199 3 Fiji 1995 2 Japan 1989 2 Others - 2 Age at onset (in years) Rubella vaccine not introduced before 1 January 217 Rubella vaccine introduced before 1 January 217 Notes: Based on data received 218-4 Data Source: IVB Database. RCV in RI: Rubella-containing vaccine in Routine Immunization as of 31 Dec 216.

Distribution of rubella genotypes (last 12 months) Notes: Data Source: RubNS database (Genotypes) and IVB Database (Incidence) as of 218-4-16 and covering the period 217-3-1 to 218-2-28 - Pie charts proportional to the number of sequenced viruses

Laboratory

Measles and Rubella IgM Data Summary 218 Region Member States* Specimens received Measles tested Measles positive n(%) Measles equivocal n(%) Measles negative n(%) Rubella tested Rubella positive n(%) Rubella equivocal n(%) Rubella negative n(%) AFR 26/47 2546 2546 614 (24) 59 (2) 1873 (74) 1986 339 (17) 11 (5) 1546 (78) AMR 23/35 1947 174 44 (3) 2 (1) 151 (86) 1638 59 (4) 55 (3) 1384 (84) EMR 16/21 3731 3159 945 (3) 4 () 221 (7) 2769 141 (5) 18 (1) 261 (94) EUR 35/53 871 8535 254 (29) 75 (1) 5856 (69) 4793 84 (2) 14 () 4679 (98) SEAR 11/11 2977 2542 126 (5) 97 (4) 1181 (46) 1462 176 (12) 34 (2) 127 (87) WPR 27/27 353 3369 662 (2) 52 (2) 1727 (51) 276 93 (3) 46 (2) 1284 (47) Total 138/194 23414 21891 629 (28) 37 (1) 14348 (66) 1548 892 (6) 268 (2) 12773 (83) 217 Region Member States* Specimens received Measles tested Measles positive n(%) Measles equivocal n(%) Measles negative n(%) Rubella tested Rubella positive n(%) Rubella equivocal n(%) Rubella negative n(%) AFR 39/47 35227 35227 4639 (13) 665 (2) 29923 (85) 29657 4964 (17) 1263 (4) 2343 (79) AMR 27/35 8453 7722 215 (3) 65 (1) 6777 (88) 7219 137 (2) 118 (2) 639 (87) EMR 2/21 35426 33959 1197 (3) 127 () 23635 (7) 31658 187 (3) 99 () 3472 (96) EUR 38/53 39842 3523 13482 (38) 272 (1) 2739 (59) 24479 42 (2) 66 () 23925 (98) SEAR 11/11 35286 32241 13118 (41) 768 (2) 18332 (57) 23 4832 (24) 733 (4) 14728 (73) WPR 27/27 16467 15211 21 (14) 333 (2) 11952 (79) 12656 66 (5) 418 (3) 1748 (85) Total 162/194 1771 159383 43751 (27) 223 (1) 111358 (7) 125969 1228 (1) 2697 (2) 19612 (87) Notes: Based on data received 218-4 - * Member States Reporting / Total Member States in Region

Performance of Surveillance

Surveillance sensitivity reporting rate of measles and rubella (12 months, discarded cases* per 1, population) Notes: Based on data received 218-4 and covering the period between 217-3 and 218-2 - Target: >= 2 discarded cases* / 1, population** - * Suspected cases investigated and discarded as non-measles non-rubella using laboratory testing and/or epidemiological linkage to another etiology ** World population prospects, 217 revision

Supplementary Immunization Activities

Next 6 months MMR, MR and Measles campaigns Region Name Activity Type Year StartDate EndDate Age Group(s) Extent Target AFR Angola CatchUp MR 218 218-4-9 218-4-23 9 M-14 Y National 12291331 AFR Mozambique CatchUp MR 218 218-4-9 218-5-25 9 M-14 Y National 1269883 AFR Benin CatchUp MR 218 218-5-21 218-5-27 9 M-14 Y National 514253 SEAR Timor-Leste FollowUp MR 218 218-7-1-9-59 M National 17 SEAR Indonesia CatchUp MR 218 218-8-1 218-9-3 9 M-15 Y Rollover-Nat 3.4e+7 AFR Ghana FollowUp MR 218 218-1-1-9-59 M National 46561

Regional Bulletins and Newsletters AFR Monthly feedback tables AMR: Weekly bulletin (published every Friday) EMR: Home page EUR : Periodical bulletin Monthly data SEAR: Monthly bulletin EPI country fact sheets WPR: Periodical newsletter Country profiles Link to global Measles Surveillance HQ website