SUPPLEMENTAL MATERIAL Table 1: International Classification of Diseases, Ninth Revision, Clinical Modification (ICD-9) codes identifying variables used to calculate propensity scores Medical Conditions ICD-9 Codes Description History of intracerebral 431 Intracerebral hemorrhage hemorrhage 1 History of Major Bleeding 1 423.0 Hemopericardium 430 Subarachnoid hemorrhage 431 Intracerebral hemorrhage 432 Other and unspecified intracranial hemorrhage 455.2 Internal hemorrhoids with other complication 455.5 External hemorrhoids with other complication 455.8 Unspecified hemorrhoids with other complication 459.0 Hemorrhage, unspecified 456.0 Esophageal varices with bleeding 456.2 Esophageal varices in diseases classified elsewhere 530.7 Gastroesophageal laceration-hemorrhage syndrome 530.8 Other specified disorders of esophagus 531.0 Acute gastric ulcer with hemorrhage 531.2 Acute gastric ulcer with hemorrhage and 531.4 Chronic or unspecified gastric ulcer with hemorrhage 531.6 Chronic or unspecified gastric ulcer with hemorrhage and 532.0 Acute duodenal ulcer with hemorrhage 532.2 Acute duodenal ulcer with hemorrhage and 532.4 Chronic or unspecified duodenal ulcer with hemorrhage 532.6 Chronic or unspecified duodenal ulcer with hemorrhage and
533.0 Acute peptic ulcer of unspecified site with hemorrhage 533.2 Acute peptic ulcer of unspecified site with hemorrhage and 533.4 Chronic or unspecified peptic ulcer of unspecified site with hemorrhage 533.6 Chronic or unspecified peptic ulcer of unspecified site with hemorrhage and 534.0 Acute gastrojejunal ulcer with hemorrhage 534.2 Acute gastrojejunal ulcer with hemorrhage and 534.4 Chronic or unspecified gastrojejunal ulcer with hemorrhage 534.6 Chronic or unspecified gastrojejunal ulcer with hemorrhage and 535.0 Acute gastritis 535.1 Atrophic gastritis 535.2 Gastric mucosal hypertrophy 535.3 Alcoholic gastritis 535.4 Other specified gastritis 535.5 Unspecified gastritis and gastroduodenitis 535.6 Duodenitis 537.8 Other specified disorders of stomach and duodenum 562.0 Diverticula of small intestine 562.1 Diverticula of colon 568.8 Other specified disorders of peritoneum 569.3 Hemorrhage of rectum and anus 569.85 Angiodysplasia of intestine with hemorrhage 578 Gastrointestinal hemorrhage 593.8 Other specified disorders of kidney and ureter 599.7 Hematuria
623.8 Other specified noninflammatory disorders of vagina 626.2 Excessive or frequent menstruation 626.6 Metrorrhagia 719.10 Hemarthrosis, site unspecified 719.11 Hemarthrosis, shoulder region 719.12 Hemarthrosis, upper arm 719.13 Hemarthrosis, forearm 719.14 Hemarthrosis, hand 719.15 Hemarthrosis, pelvic region and thigh 719.16 Hemarthrosis, lower leg 719.17 Hemarthrosis, ankle and foot 719.18 Hemarthrosis, other specified sites 784.7 Epistaxis 786.3 Hemoptysis 852 Subarachnoid subdural and extradural hemorrhage following injury 853 Other and unspecified intracranial hemorrhage following injury Congestive heart failure used to calculate CHADS 2 score 2 398.91 Rheumatic heart failure (congestive) 402.01 Malignant hypertensive heart disease with heart failure 402.11 Benign hypertensive heart disease with heart failure 402.91 Unspecified hypertensive heart disease with heart failure 428.x Heart failure 518.4 Acute edema of lung unspecified Stroke/TIA used to calculate CHADS 2 score 2 434 Occlusion of cerebral arteries 435 Transient cerebral ischemia 436 Acute but ill-defined cerebrovascular disease Diabetes used to calculate 250.x Diabetes CHADS 2 score 2
Hypertension used to calculate CHADS 2 score 2 401.x Essential hypertension 402.x Hypertensive heart disease 403.x Hypertensive chronic kidney disease 404.x Hypertensive heart and chronic kidney disease 405.x Secondary hypertension Rebleeding Risk - Prior bleed used to calculate HEMORR 2 HAGES score 430.xx 431.xx 432.xx Subarachnoid hemorrhage Intracerebral hemorrhage Other and unspecified intracranial hemorrhage 3, 4 E934.2 Anticoagulants causing adverse effects in therapeutic use 246.3 Hemorrhage and infarction of thyroid 286.5 Hemorrhagic disorder due to intrinsic circulating anticoagulants 362.81 Hemorrhagic disorder due to intrinsic circulating anticoagulants 363.61 Choroidal hemorrhage unspecified 363.62 Expulsive choroidal hemorrhage 379.23 Vitreous hemorrhage 386.8 Other disorders of labyrinth 388.69 Other otorrhea 448.9 Other and unspecified capillary diseases 456.0 Esophageal varices with bleeding 456.20 Esophageal varices in disease classified elsewhere, with bleeding 459.0 Other disorders of circulatory system 523.8 Other specified periodontal diseases 528.9 Other and unspecified diseases of the oral soft tissues 530.82 Esophageal hemorrhage 531.0 Acute gastric ulcer with hemorrhage 531.2 Acute gastric ulcer with hemorrhage and 531.4 Chronic or unspecified gastric ulcer with hemorrhage
531.6 Chronic or unspecified gastric ulcer with hemorrhage and 532.0 Acute duodenal ulcer with hemorrhage 532.2 Acute duodenal ulcer with hemorrhage and 532.4 Chronic or unspecified duodenal ulcer with hemorrhage 532.6 Chronic or unspecified duodenal ulcer with hemorrhage and 533.0 Peptic ulcer site unspecified 533.2 Acute peptic ulcer of unspecified site with hemorrhage and 533.4 Chronic or unspecified peptic ulcer of unspecified site with hemorrhage 533.6 Chronic or unspecified peptic ulcer of unspecified site with hemorrhage and 534.0 Acute gastrojejunal ulcer with hemorrhage 534.2 Acute gastrojejunal ulcer with hemorrhage and 534.4 Chronic or unspecified gastrojejunal ulcer with hemorrhage 534.6 Chronic or unspecified gastrojejunal ulcer with hemorrhage and 537.83 Angiodysplasia of stomach and duodenum with hemorrhage 562.03 Diverticulitis of small intestine with hemorrhage 562.13 Diverticulitis of colon with hemorrhage 568.81 Hemoperitoneum (nontraumatic) 569.3 Hemorrhage of rectum and anus 569.83 Perforation of intestine 578.xx Gastrointestinal hemorrhage 596.8 Other specified disorders of bladder 599.7 Hematuria
626.6 Metrorrhagia 627.1 Postmenopausal bleeding 719.1x Hemarthrosis 727.89 Other disorders of synovium tendon and bursa 784.7 Epistaxis 784.8 Hemorrhage from throat 786.3 Hemoptysis 958.2 Secondary and recurrent hemorrhage as an early complication of trauma Hepatic or renal disease used to calculate HEMORR 2 HAGES score 3 identified using codes coinciding with end stage renal disease, cirrhosis, and high creatinine 570 Acute and subacute necrosis of liver 571.4x Chronic hepatitis 571.5 Cirrhosis of liver without mention of alcohol 571.6 Biliary cirrhosis 571.8 Other chronic nonalcoholic liver disease 571.9 Unspecified chronic liver disease without mention of alcohol 572 Liver abscess and sequelae of chronic liver disease 573 Other disorders of liver 585 Chronic kidney disease (ckd) 585.3 Chronic kidney disease, stage iii (moderate) 585.4 Chronic kidney disease, stage iv (severe) 585.5 Chronic kidney disease, stage v 585.6 End stage renal disease 585.9 Chronic kidney disease, unspecified 794.4 Nonspecific abnormal results of function study of kidney Ethanol (Alcohol) abuse used to calculate HEMORR 2 HAGES score 3 291.0 Alcohol withdrawal delirium 291.1 Alcohol-induced persisting amnestic disorder 291.2 Alcohol-induced persisting dementia 303.x Alcohol dependence syndrome
305.0x Nondependent abuse of drugs 535.3 Alcoholic gastritis 571.0 Alcoholic fatty liver 571.1 Acute alcoholic hepatitis 571.2 Alcoholic cirrhosis of liver 571.3 Alcoholic liver damage unspecified V11.3 Personal history of alcoholism Malignancy 141 Malignant neoplasm of tongue 142 Malignant neoplasm of major salivary glands 143 Malignant neoplasm of gum 144 Malignant neoplasm of floor of mouth 145 Malignant neoplasm of other and unspecified parts of mouth 146 Malignant neoplasm of oropharynx 147 Malignant neoplasm of nasopharynx 148 Malignant neoplasm of hypopharynx 149 Malignant neoplasm of other and ill-defined sites within the lip oral cavity and pharynx 150 Malignant neoplasm of esophagus 151 Malignant neoplasm of stomach 152 Malignant neoplasm of small intestine including duodenum 153 Malignant neoplasm of colon 154 Malignant neoplasm of rectum rectosigmoid junction and anus 155 Malignant neoplasm of liver and intrahepatic bile ducts 156 Malignant neoplasm of gallbladder and extrahepatic bile ducts 157 Malignant neoplasm of pancreas 158 Malignant neoplasm of retroperitoneum and peritoneum 159 Malignant neoplasm of other and ill-defined sites within the digestive organs and peritoneum
160 Malignant neoplasm of nasal cavities middle ear and accessory sinuses 161 Malignant neoplasm of larynx 162 Malignant neoplasm of trachea bronchus and lung 163 Malignant neoplasm of pleura 164 Malignant neoplasm of thymus heart and mediastinum 165 Malignant neoplasm of other and ill-defined sites within the respiratory system and intrathoracic organs 166 No match 167 No match 168 No match 169 No match 170 Malignant neoplasm of bone and articular cartilage 171 Malignant neoplasm of connective and other soft tissue 172 Malignant melanoma of skin 174 Malignant neoplasm of female breast 175 Malignant neoplasm of female breast 176 Kaposi's sarcoma 177 No match 178 No match 179 Malignant neoplasm of uterus-part unspecified 180 Malignant neoplasm of cervix uteri 181 Malignant neoplasm of placenta 182 Malignant neoplasm of body of uterus 183 Malignant neoplasm of ovary and other uterine adnexa 184 Malignant neoplasm of other and unspecified female genital organs 185 Malignant neoplasm of prostate
186 Malignant neoplasm of testis 187 Malignant neoplasm of penis and other male genital organs 188 Malignant neoplasm of bladder 189 Malignant neoplasm of kidney and other and unspecified urinary organs 190 Malignant neoplasm of eye 191 Malignant neoplasm of brain 192 Malignant neoplasm of other and unspecified parts of nervous system 193 Malignant neoplasm of thyroid gland 194 Malignant neoplasm of other endocrine glands and related structures 195 Malignant neoplasm of other and ill-defined sites 196 Secondary and unspecified malignant neoplasm of lymph nodes 197 Secondary malignant neoplasm of respiratory and digestive systems 198 Secondary malignant neoplasm of other specified sites 199 Malignant neoplasm without specification of site 200 Lymphosarcoma and reticulosarcoma and other specified malignant tumors of lymphatic tissue 201 Hodgkin's disease 202 Other malignant neoplasms of lymphoid and histiocytic tissue 203 Multiple myeloma and immunoproliferative neoplasms 204 Lymphoid leukemia 205 Myeloid leukemia 206 Monocytic leukemia 207 Other specified leukemia 208 Leukemia of unspecified cell type
Reduced platelet count or 287.x Purpura and other hemorrhagic conditions function used to calculate HEMORR 2 HAGES score 3 identified using codes coinciding with reduced platelet count or function Hypertension used to calculate HEMORR 2 HAGES score 3 401.x Essential hypertension 402.x Hypertensive heart disease 403.x Hypertensive chronic kidney disease 404.x Hypertensive heart and chronic kidney disease 405.x Secondary hypertension Anemia used to calculate HEMORR 2 HAGES score 3 280.x Iron deficiency anemias 281.x Other deficiency anemias 282.0 Hereditary spherocytosis 282.1 Hereditary elliptocytosis 282.2 Anemias due to disorders of glutathione metabolism 282.3 Other hemolytic anemias due to enzyme deficiency 282.4 Thalassemias 282.60 Sickle-cell disease unspecified 282.69 Other sickle-cell disease with crisis 283.x Acquired hemolytic anemias 284.x Aplastic anemia and other bone marrow failure syndromes 285.x Other and unspecified anemias Excessive fall risk or neuropsychiatric disease E880 E888 Accidental fall on or from stairs or steps Other and unspecified fall used to calculate HEMORR 2 HAGES score 3 identified using codes 332 Parkinson's disease 334 Spinocerebellar disease 781.2 Abnormality of gait
coinciding with falling, dementia, Parkinson diesease, or psychiatric disease 290.0 Senile dementia uncomplicated 294.0 Amnestic disorder in conditions classified elsewhere 458.0 Orthostatic hypotension 780.4 Dizziness and giddiness 357.2 Polyneuropathy in diabetes 357.5 Alcoholic polyneuropathy 296.0 Bipolar i disorder, single manic episode 296.4 Bipolar i disorder, most recent episode (or current) manic 296.89 Bipolar disorder, other 296.2 Major depressive disorder single episode 296.3 Major depressive disorder recurrent episode 311 Depressive disorder not elsewhere classified 295 Schizophrenic disorders 295.0 Simple type schizophrenia 295.1 Disorganized type schizophrenia 295.2 Catatonic type schizophrenia 295.3 Paranoid type schizophrenia 295.4 Schizophreniform disorder 295.5 Latent schizophrenia 295.6 Schizophrenic disorder, residual type 295.7 Schizoaffective disorder 295.8 Other specified types of schizophrenia 295.9 Unspecified schizophrenia 297 Delusional disorders 297.0 Paranoid state simple 297.1 Delusional disorder 297.2 Paraphrenia 297.3 Shared psychotic disorder
297.8 Other specified paranoid states 297.9 Unspecified paranoid state Prior stroke used to calculate Charlson Myocardial infarction used to calculate Charlson 434 Occlusion of cerebral arteries 435 Transient cerebral ischemia 436 Acute but ill-defined cerebrovascular disease 410 Acute myocardial infarction 412 Old myocardial infarction Congestive heart failure 428 Heart failure used to calculate Charlson Peripheral vascular disease used to calculate Charlson Comorbidity 441 Aortic aneurysm and dissection 443.9 Peripheral vascular disease, unspecified 785.4 Gangrene Index 5 V434 Occlusion of cerebral arteries NOT PVD 38.48 Resection and replacement of lower limb arteries Cerebrovascular disease used to calculate Charlson 430 Subarachnoid hemorrhage If traumatic the vessels may be normal 431 Intracerebral hemorrhage ditto 432 Other and unspecified intracranial hemorrhage ditto 433 Occlusion and stenosis of precerebral arteries 434 Occlusion of cerebral arteries 435 Transient cerebral ischemia 436 Acute but ill-defined cerebrovascular disease 437 Other and ill-defined cerebrovascular disease 438 Late effects of cerebrovascular disease Dementia used to 290 Dementias calculate Charlson
Chronic pulmonary disease used to calculate Charlson Comorbidity Index 5 490 Bronchitis not specified as acute or chronic 491 Chronic bronchitis 492 Emphysema 493 Asthma 494 Bronchiectasis 495 Extrinsic allergic alveolitis 496 Chronic airway obstruction not elsewhere classified 500 Coal workers' pneumoconiosis 501 Asbestosis 502 Pneumoconiosis due to other silica or silicates 503 Pneumoconiosis due to other inorganic dust 504 Pneumonopathy due to inhalation of other dust 505 Pneumoconiosis unspecified 506.4 Chronic respiratory conditions due to fumes and vapors Rheumatologic disease used to calculate Charlson 710.0 Systemic lupus erythematosus 710.1 Systemic sclerosis 710.4 Polymyositis 714.0 Rheumatoid arthritis 714.1 Felty's syndrome 714.2 Other rheumatoid arthritis with visceral or systemic involvement 725 Polymyalgia rheumatica 714.81 Rheumatoid lung Peptic ulcer disease used to calculate Charlson 531.0 Acute gastric ulcer with hemorrhage 531.00 Acute gastric ulcer with hemorrhage without obstruction 531.01 Acute gastric ulcer with hemorrhage with obstruction 531.1 Acute gastric ulcer with without obstruction 531.11 Acute gastric ulcer with with obstruction
531.2 Acute gastric ulcer with hemorrhage and 531.2 Acute gastric ulcer with hemorrhage and without obstruction 531.21 Acute gastric ulcer with hemorrhage and with obstruction 531.3 Acute gastric ulcer without mention of hemorrhage or 531.3 Acute gastric ulcer without hemorrhage or without obstruction 531.31 Acute gastric ulcer without hemorrhage or with obstruction 531.9 Gastric ulcer unspecified as acute or chronic without mention of hemorrhage or 531.9 Gastric ulcer unspecified as acute or chronic without hemorrhage or without obstruction 531.91 Gastric ulcer unspecified as acute or chronic without hemorrhage or with obstruction 532.0 Acute duodenal ulcer with hemorrhage 532.00 Acute duodenal ulcer with hemorrhage without obstruction 532.01 532.01 Acute duodenal ulcer with hemorrhage with obstruction 533.1 Acute duodenal ulcer with 532.1 Acute duodenal ulcer with without obstruction 532.11 Acute duodenal ulcer with with obstruction 532.2 Acute duodenal ulcer with hemorrhage and 532.2 Acute duodenal ulcer with hemorrhage and without obstruction 532.21 Acute duodenal ulcer with hemorrhage and with obstruction
532.3 Acute duodenal ulcer without mention of hemorrhage or 532.3 Acute duodenal ulcer without hemorrhage or without obstruction 532.31 Acute duodenal ulcer without hemorrhage or with obstruction 533.0 Acute peptic ulcer of unspecified site with hemorrhage 533.00 Acute peptic ulcer of unspecified site with hemorrhage without obstruction 533.01 Acute peptic ulcer of unspecified site with hemorrhage with obstruction 533.4 Chronic or unspecified peptic ulcer of unspecified site with hemorrhage 534.0 Acute gastrojejunal ulcer with hemorrhage 534.1 Acute gastrojejunal ulcer with 534.2 Acute gastrojejunal ulcer with hemorrhage and 534.3 Acute gastrojejunal ulcer without mention of hemorrhage or 534.4 Chronic or unspecified gastrojejunal ulcer with hemorrhage 534.5 Chronic or unspecified gastrojejunal ulcer with 534.6 Chronic or unspecified gastrojejunal ulcer with hemorrhage and 534.7 Chronic gastrojejunal ulcer without mention of hemorrhage or 534.8 No match 534.9 Gastrojejunal ulcer unspecified as acute or chronic without mention of hemorrhage or Mild liver disease used to 571.2 Alcoholic cirrhosis of liver
calculate Charlson 571.4 Chronic hepatitis 571.5 Cirrhosis of liver without alcohol 571.6 Biliary cirrhosis Diabetes (mild to moderate) used to calculate Charlson 250.0 Diabetes mellitus without mention of complication 250.1 Diabetes with ketoacidosis 250.2 Diabetes with hyperosmolarity 250.3 Diabetes with other coma 250.7 Diabetes with peripheral circulatory disorders Diabetes with chronic complications used to calculate Charlson 250.4 Diabetes with renal manifestations 250.5 Diabetes with ophthalmic manifestations 250.6 Diabetes with neurological manifestations Hemiplegia or paraplegia used to calculate Charlson 342 Hemiplegia and hemiparesis 344.1 Paraplegi Renal disease used to calculate Charlson 582 Chronic glomerulonephritis 585 Chronic kidney disease (ckd) 586 Renal failure unspecified 588 Disorders resulting from impaired renal function 583.0 Nephritis and nephropathy not specified as acute or chronic with lesion of proliferative glomerulonephritis 583.1 Nephritis and nephropathy, not specified as acute or chronic, with lesion of membranous glomerulonephritis 583.2 Nephritis and nephropathy, not specified as acute or chronic, with lesion of membranoproliferative glomerulonephritis 583.4 Nephritis and nephropathy, not specified as acute or chronic, with lesion of rapidly progressive glomerulonephritis 583.6 Nephritis and nephropathy, not specified as acute or chronic,
with lesion of renal cortical necrosis 583.7 Nephritis and nephropathy not specified as acute or chronic with lesion of renal medullary necrosis Any malignancy, including lymphoma and leukemia used to calculate Charlson Comorbidity Index 5 140 Malignant neoplasm of lip 141 Malignant neoplasm of tongue 142 Malignant neoplasm of major salivary glands 143 Malignant neoplasm of gum 144 Malignant neoplasm of floor of mouth 145 Malignant neoplasm of other and unspecified parts of mouth 146 Malignant neoplasm of oropharynx 147 Malignant neoplasm of nasopharynx 148 Malignant neoplasm of hypopharynx 149 Malignant neoplasm of other and ill-defined sites within the lip oral cavity and pharynx 150 Malignant neoplasm of esophagus 151 Malignant neoplasm of stomach 152 Malignant neoplasm of small intestine including duodenum 153 Malignant neoplasm of colon 154 Malignant neoplasm of rectum rectosigmoid junction and anus 155 Malignant neoplasm of liver and intrahepatic bile ducts 156 Malignant neoplasm of gallbladder and extrahepatic bile ducts 157 Malignant neoplasm of pancreas 158 Malignant neoplasm of retroperitoneum and peritoneum 159 Malignant neoplasm of other and ill-defined sites within the digestive organs and peritoneum 160 Malignant neoplasm of nasal cavities middle ear and accessory sinuses 161 Malignant neoplasm of larynx
162 Malignant neoplasm of trachea bronchus and lung 163 Malignant neoplasm of pleura 164 Malignant neoplasm of thymus heart and mediastinum 165 Malignant neoplasm of other and ill-defined sites within the respiratory system and intrathoracic organs 166 No match 167 No match 168 No match 169 No match 170 Malignant neoplasm of bone and articular cartilage 171 Malignant neoplasm of connective and other soft tissue 172.0 Malignant melanoma of skin 172.1 Malignant melanoma of skin of eyelid including canthus 172.2 Malignant melanoma of skin of ear and external auditory canal 172.3 Malignant melanoma of skin of other and unspecified parts of face 172.4 Malignant melanoma of skin of scalp and neck 172.5 Malignant melanoma of skin of trunk except scrotum 172.6 Malignant melanoma of skin of upper limb including shoulder 172.7 Malignant melanoma of skin of lower limb including hip 172.8 Malignant melanoma of other specified sites of skin 172.9 Melanoma of skin site unspecified 174 Malignant neoplasm of female breast 175 Malignant neoplasm of male breast 176 Kaposi's sarcoma 177 No match 178 No match 179 Malignant neoplasm of uterus-part unspecified
180 Malignant neoplasm of cervix uteri 181 Malignant neoplasm of placenta 182 Malignant neoplasm of body of uterus 183 Malignant neoplasm of ovary and other uterine adnexa 184 Malignant neoplasm of other and unspecified female genital organs 185 Malignant neoplasm of prostate 186 Malignant neoplasm of prostate 187 Malignant neoplasm of penis and other male genital organs 188 Malignant neoplasm of bladder 189 Malignant neoplasm of kidney and other and unspecified urinary organs 190 Malignant neoplasm of eye 191 Malignant neoplasm of brain 192 Malignant neoplasm of other and unspecified parts of nervous system 193 Malignant neoplasm of thyroid gland 194 Malignant neoplasm of other endocrine glands and related structures 195 Malignant neoplasm of other and ill-defined sites 200 Lymphosarcoma and reticulosarcoma and other specified malignant tumors of lymphatic tissue 201 Hodgkin's disease 202 Other malignant neoplasms of lymphoid and histiocytic tissue 203 Multiple myeloma and immunoproliferative neoplasms 204 Lymphoid leukemia 205 Myeloid leukemia 206 Monocytic leukemia
207 Other specified leukemia 208 Leukemia of unspecified cell type Moderate or severe liver disease used to calculate Charlson Comorbidity Index 5 572.2 Hepatic encephalopathy 572.3 ortal hypertension 572.4 Hepatorenal syndrome 572.8 Other sequelae of chronic liver disease 456.0 Esophageal varices with bleeding 456.1 Esophageal varices without mention of bleeding 456.2 Esophageal varices in diseases classified elsewhere Metastatic solid tumor used to calculate Charlson 196.0 Secondary and unspecified malignant neoplasm of lymph nodes of head face and neck 196.1 Secondary and unspecified malignant neoplasm of intrathoracic lymph nodes 196.2 Secondary and unspecified malignant neoplasm of intraabdominal lymph nodes 196.3 Secondary and unspecified malignant neoplasm of lymph nodes of axilla and upper limb 196.5 Secondary and unspecified malignant neoplasm of lymph nodes of inguinal region and lower limb 196.6 Secondary and unspecified malignant neoplasm of intrapelvic lymph nodes 196.8 Secondary and unspecified malignant neoplasm of lymph nodes of multiple sites 196.9 Secondary and unspecified malignant neoplasm of lymph nodes site unspecified 197.0 Secondary malignant neoplasm of lung 197.1 Secondary malignant neoplasm of mediastinum 197.2 Secondary malignant neoplasm of pleura
197.3 Secondary malignant neoplasm of other respiratory organs 197.4 Secondary malignant neoplasm of small intestine including duodenum 197.5 Secondary malignant neoplasm of large intestine and rectum 197.6 Secondary malignant neoplasm of retroperitoneum and peritoneum 197.7 Malignant neoplasm of liver secondary 197.8 Secondary malignant neoplasm of other digestive organs and spleen 198.0 Secondary malignant neoplasm of kidney 198.1 Secondary malignant neoplasm of other urinary organs 198.2 Secondary malignant neoplasm of skin 198.3 Secondary malignant neoplasm of brain and spinal cord 198.4 Secondary malignant neoplasm of other parts of nervous system 198.5 Secondary malignant neoplasm of bone and bone marrow 198.6 Secondary malignant neoplasm of ovary 198.7 Secondary malignant neoplasm of adrenal gland 198.8 Secondary malignant neoplasm of other specified sites 199.0 Disseminated malignant neoplasm 199.1 Other malignant neoplasm of unspecified site AIDS used to calculate Charlson Comorbidity Index 5 42 Human immunodeficiency virus (hiv) disease 43 No match 44 No match
Supplemental References 1. White RH, Beyth RJ, Zhou H, Romano PS. Major bleeding after hospitalization for deep-venous thrombosis. Am J Med. 1999;107:414-424. 2. Gage BF, Waterman AD, Shannon W, Boechler M, Rich MW, Radford MJ. Validation of clinical classification schemes for predicting stroke: results from the National Registry of Atrial Fibrillation. JAMA. 2001;285:2864-2870. 3. Gage BF, Yan Y, Milligan PE, Waterman AD, Culverhouse R, Rich MW, Radford MJ. Clinical classification schemes for predicting hemorrhage: results from the National Registry of Atrial Fibrillation (NRAF). Am Heart J. 2006;151:713-719. 4. Harley CR, Riedel AA, Hauch O, Nelson M, Wygant G, Reynolds M. Anticoagulation therapy in patients with chronic atrial fibrillation: a retrospective claims data analysis. Curr Med Res Opin. 2005;21:215-222. 5. Deyo RA, Cherkin DC, Ciol MA. Adapting a clinical comorbidity index for use with ICD-9-CM administrative databases. J Clin Epidemiol. 1992;45:613-619.