New Brunswick Report on Sexually Transmitted and Blood Borne Infections, 2016

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New Brunswick Report on Sexually Transmitted and Blood Borne Infections, 6

Table of Contents. Introduction.... Methodology... 3. Data Limitations.... Definitions used... 3 5. Overview of STBBI epidemiology in New Brunswick, 6... 3 6. Specific Diseases... A. Chlamydia... i. Overview... B. Gonorrhea... 6 i. Overview... 6 ii. Risk Factors... 7 C. Hepatitis B... 9 i. Acute hepatitis B... 9 ii. Chronic hepatitis B... D. Hepatitis C... 3 i. Overview... ii. Risk Factors... E. HIV/AIDS... 6 i. HIV... 6 ii. AIDS... 7 F. Infectious Syphilis... 7 i. Overview... 7 ii. Risk Factors... 8 7. Summary and conclusion... Appendix... Appendix... 3 Appendix 3... 3 Appendix... Page

New Brunswick Report on Sexually Transmitted and Blood Borne Infections Enhanced surveillance data, 6. Introduction Under the Public Health Act of New Brunswick, select sexually transmitted and blood borne infections (STBBIs) are reported to Regional Public Health and subsequently to the Office of the Chief Medical Officer of Health (OCMOH). Included among these STBBIs are chlamydia, gonococcal Infections, syphilis, hepatitis B, hepatitis C, and Human Immunodeficiency Virus/Acquired Immunodeficiency Syndrome (HIV/AIDS). In 6, an enhanced surveillance program for all reportable STBBIs except chlamydia was implemented to better describe risk factors among patients and identify at-risk groups for the purpose of informing the prevention and control of STBBIs in New Brunswick.. Methodology Data collection begins in the seven Health Regions in New Brunswick (See map in Appendix ). All positive laboratory-confirmed cases are sent to Regional Public Health. Basic information on all reportable STBBIs is entered into the Reportable Diseases Surveillance System (RDSS). In addition, cases (excluding chlamydia) are followed up with an enhanced surveillance questionnaire by Public Health Nurses to assess risk factors. Information obtained from the enhanced surveillance is entered into a database designed for that purpose. The seven Health Regions extract a monthly line list of all cases and send the data to the Office of the Chief Medical Officer of Health (OCMOH). 3. Data Limitations It should be noted that the numbers cited in this report reflect only those of confirmed cases that meet the National Case Definitions and which are reported to Public Health. As a result, the data may underrepresent the true number of cases in the population. This is particularly relevant for those diseases where cases remain asymptomatic or diseases that have a wide clinical spectrum. Numbers and rates in the report are based on 6 notifications received as April 7, and may be subject to minor changes in future reports. Please use caution when interpreting age-specific, gender-specific or region-specific annual incidence rates for some diseases: the relatively low number of cases can result in major fluctuations in the rate from year to year. Page

Pourcentage National data provided by the Public Health Agency of Canada (PHAC) that are used in this report are also subject to change.. Definitions used Men Having Sex with Men (MSM): Sexual orientation can be homosexual, bisexual. Types of sexual partners: Regular partner: a sexual partner with whom you have an emotional connection Casual partner: a sexual partner with whom you have no emotional connection Anonymous partner: a sexual partner of unknown identity Paraphernalia: snorting, sniffing or smoking equipment used during illicit drug use. 5. Overview of STBBI epidemiology in New Brunswick, 6 The most common reported STBBI is chlamydia, followed by hepatitis C (unspecified) and chronic hepatitis B. In 6, higher incidence rates of chlamydia, gonorrhea, chronic and acute hepatitis B, and AIDS were observed compared to the previous 5-year average. However, incidence rates remained stable for cases of hepatitis C and HIV and incidence rate was lower for Syphilis. Individuals aged to 39 years old were the highest affected (highest incidence rates) by overall reportable STBBIs. Graph. Sexually Transmitted and Blood Borne Infections (STBBI) in New Brunswick, 6 % 8% 8% 6% % % % 8% Chlamydia Hepatitis C Hepatitis B (acute and chronic) 3% 3% %.5% Gonorrhea Syphilis (infectious) HIV/AIDS Page 3

Rates per, population Rates per, population Rates per, population Figure. Age specific incidence rates by sex for different reportable STBBIs (excluding Chlamydia), New Brunswick, 6 A. Incidence rates by Disease and Age without Chlamydia 8 6 Gonorrhea Syphilis (Infectious) Hepatitis B Hepatitis C HIV/AIDS < 5.9. 5.3.. -39 9.3 7.3 8.6 5.7.8-59 5.. 5. 5.. 6+....8.5 8 B. Incidence rates by Disease and Age for Males C. Incidence rates by Disease and Age for Females 8 6 6 Gonorrhea Syphilis (Infectious) Hepatitis B Hepatitis C HIV/AIDS <.6. 5..6. -39 3. 3. 8.7 66.. -59 6..9.9 39..9 6+... 7.8. Gonorrhea Syphilis (Infectious) Hepatitis B Hepatitis C HIV/AIDS < 9.5. 5. 5.. -39.. 8.5.7 3.5-59.. 8.8. 3.5 6+...8.6. 6. Specific Diseases A. Chlamydia i. Overview Chlamydia is the most commonly reported sexually transmitted infection. In 6, 98 chlamydia cases were reported with an incidence rate of 5.8 per, population. In the past 5 years, the average case count was 86 cases per year, with a 5-year average incidence rate of.5 per, population. After a slight decrease in 3 and, the incidence rate increased in 5 and 6 to comparable levels to years prior to 3. Overall, the incidence rate for New Brunswick is lower than the Canadian rate. Page

Rate per, population Rates per, population Females remain largely overrepresented among chlamydia cases, accounting for more than two thirds of all notifications (66%) in 6. In 6, higher incidence rates were observed in all age groups, compared to their 5-year average, with the highest incidence rate observed amongst young adults aged to years old in both males and females. Compared to 5, the highest increases in incidence rates were observed in Region, followed by Region 5 and Region 3. Graph. Chlamydia Incidence Rates per, population Overall and by Sex for New Brunswick and Canada, -6. 3.... 3 5 6 NB Rates (Males) 6.3 6.8 57. 5.3 78.3 77. NB Rates (Females) 3.7 33.6 38.8 38. 38.8 33.3 NB Rates 53.5 55. 33.8 3.5 9. 5.8 Canadian Rates 9. 98.7 95.8 37. 3.9 Graph 3. Chlamydia Case Counts and Incidence Rate per, by Sex and Age group, New Brunswick, -6 5.. 5.. 5.. <5 5-9 - 5-9 3-39 -59 6+ <5 5-9 - 5-9 3-39 -59 6+ Male Female 6 Count 7 9 6 389 76 7 9 37-5 Average Count 59 33 85 8 3 8 389 5 88 6 3 6 Rate. 7. 3.6 673.9 5.5 36.5.. 989. 98.3 93. 9.8 3..9-5 Average Rate. 39. 59.9 589.5 85. 5. 3. 5. 87.8 6. 885. 5.3.. Page 5

Rates per, population B. Gonorrhea i. Overview In 6, 73 cases of gonorrhea were reported to Public Health with an incidence rate of 9.6 cases per, people. This is the highest number of cases and incidence rate reported in years. Despite this increase, rates for gonorrhea in New Brunswick continue to be well below national rates. Most of the cases were reported in Regions (3 cases), Region 3 ( cases) and Region ( cases). 68% of the cases (5 cases) occurred in the second half of 6, of which 3 cases were females. The number of reported male cases (n=) slightly increased compared to the previous 5-year average (n=3). Four male cases had previously repeated gonorrhea infections. An increasing trend started to be observed among females in and 5, and continued in 6. A similar increase was noted in and, possibly related to increase testing due to the chlamydia campaign at that time, as well as the - syphilis outbreak. On average, male cases were almost double female cases: 5-year average female to male ratio was :.8. There was a disproportionate increase in female cases compared to male cases that was observed in 5 which continued in 6 with a female to male ratio of :.. The increase in the male cases was mainly noted among individuals aged to 9 years old, with the highest incidence observed among those aged 5 to 9 years old. On the other hand, the increase in female cases was mainly among those aged 5 to years old age, with the highest incidence observed among those in the to years age group. The changes in annual age-specific and region- specific rates for gonorrhea should be interpreted with caution; low numbers can cause large fluctuations in rates. Graph. Gonorrhea Incidence Rates per, population Overall and by Sex for New Brunswick and Canada, -6 6.... 3 5 6 NB Rates (Males). 6.9 8.8 8.6 7.5.7 NB Rates (Females) 8. 3. 3.7 3. 5.8 8.6 NB Rates 9. 5. 6. 5.8 6.6 9.6 Canadian Rates 33. 36. 39.3 5.8 55.36 National data are presumably a mix of genital and extra-genital gonorrhea cases Page 6

Percentage of cases Rate per, population Graph 5. Gonorrhea Case Counts and Incidence Rate per, by Sex and Age group, New Brunswick, -6 7 6 5 3 <5 5-9 - 5-9 3-39 -59 6+ <5 5-9 - 5-9 3-39 -59 6+ Male Female 6 Counts 6 7 7 7 5-5 Average Count. 5. 9.8 5. 7. 3.8.. 5. 6. 3.6 3... 6 Rate. 9.3 6. 63.3 3. 6... 35.8 6. 9.3 5.8.. -5 Average Rate..7. 3.9 5.7 3.3...7 7. 7. 6.9.. ii. Risk Factors Among males who provided information on their sexual orientation, 53% identified themselves as men having sex with men (MSM), whereas.5% of females have identified themselves as bisexual. Highrisk sexual behavior was noted in both male and female gonorrhea cases. In the 6 days prior to the interview, % of male cases and % of female cases had 3 or more sexual partners. 6% of male cases had casual or anonymous sexual partners; whereas, 5% of female cases had casual or anonymous partners. Practicing unsafe sex, whether vaginal, oral or anal, was noted in both male and female cases. This was particularly prominent in those practicing oral sex, for which 96% of females and 7% of males have either never used condoms or rarely used it in the months prior to the interview. Graph 6. Condom use among male gonorrhea cases* in New Brunswick, 6 % 8% 6% % % % 8% % 9% % Oral sex (n=3) 9% % 57% Vaginal sex (n=) % 35% 9% % Anal sex (n=7) % Rimming (n=) Graph 7. Condom use among female gonorrhea cases* in New Brunswick, 6 % 8% 6% % % % 8% 3% 3% 6% 7% % 7% Oral sex (n=5) Vaginal sex (n=3) 33% 33% 33% 5% 5% Anal sex (n=3) Rimming (n=) Never use condom Condom use some time Condom use everytime condom use * only cases reporting practicing oral, vaginal, anal sex or rimming are represented Page 7

Table. Socio-demographic and behavioral risk factors in male and female gonorrhea cases in 6, New Brunswick Sociodemographic and behavioral RF Males (N=) Females (N=33) Median age in years (range) 5 8-58) 5 (6-57) Reason for testing Symptomatic Routine STI check-up 8 5 8 Pregnancy screening Contact of case N/A 6 3 3 Co-infection Chlamydia: 8, HIV: Chlamydia: 9 Sexual orientation Heterosexual Homosexual Bisexual # of sexual partners 3-9 #of cases by type of sexual partners* Regular Casual Anonymous Out of province Practicing oral sex: Yes/Total answered % condom use for oral sex Never Some of the time Every time Practicing vaginal sex: Yes/Total answered % condom use for vaginal sex Never Some of the time Every time Practicing anal sex: Yes/Total answered % condom use for anal sex Never Some of the time Every time *Not mutually exclusive. 5 6 8 9 8 7 3/7 8% % 9% % / % 9% % 36% 7/3 % 35% 9% % 8 6 3 8 8 5/8 8% 6% % % 3/3 3% 3% 7% 7% 3/8 % 33% 33% 33% Page 8

Case counts Rate per, population C. Hepatitis B Acute HBV infection can clear spontaneously or progress to chronic infection. i. Acute hepatitis B Overview In 6, there were cases of acute hepatitis B reported to Public Health with an incidence rate of.3 cases per, people. This was the highest number of cases reported in the last years. All the cases were males from Region. The median age of the cases was 7 years old (age range 3-58 years). Individuals aged between 5 and 59 years old represented 7% of all cases. Most of the cases (6%) were reported between September and November 6. Risk Factors Seventy percent of the cases identified themselves as MSM. None had previously received the hepatitis B vaccine. Most of the cases reported high-risk sexual behavior. Forty percent had or more sexual contacts in the last months; all of the contacts were anonymous. All of those who provided information on their pattern of condom use while practicing oral sex (5 cases) never used condoms. Cases who provided information on their pattern of condom use with anal sex (3 cases) used condoms some of the time. Half of the cases reported using non-injection street drugs, with only one reporting sharing drug paraphernalia. Graph 8. Acute Hepatitis B Case Counts and Rates by sex per, population in New Brunswick, -6 8 6 3..5..5..5 3 5 6. N-B Counts (Males) N-B Counts (Females) N-B Rates (Males) N-B Rates (Females) Page 9

Rates per, population ii. Chronic hepatitis B Overview In 6, 69 cases of chronic hepatitis B were reported to Public Health with an incidence rate of 9. cases per, people. Most of the cases were reported among new immigrants (6%). These cases were mainly from endemic countries. The remainder of chronic hepatitis B cases might still have some new immigrants among them; however, this could not be confirmed by the information we are currently collecting. The number of cases reported in 6 was the highest reported in the last years. Ninety-four percent of the cases were reported in Region 3 (%), Region (38%) and Region (6%). Males represented 56% of all chronic hepatitis B cases reported, with 35% among those age to 9 years old and 9% among this age 3 to 3 years old. Among females, % were between 35 and 39 years old and 6% were in the 5-9 years age group. Cases aged 3-39 years old had the highest rate among males, whereas cases aged 5-9 years old had highest rates old among females. The median age of all cases was 37 years old (range -75 years). Graph 9. Hepatitis B (acute and chronic) Incidence Rates per, population Overall and by Sex for New Brunswick and Canada, -6 6.... 8. 6.... 3 5 6 NB Rates-Males (Acute and Chronic) 5.6 7.7 7. 7. 7.5.6 NB Rates-Females (Acute and Chronic).9 3..7 3.. 8. NB-Rates (Acute and Chronic). 5.5 5.8 5. 5.8. Canadian Rates (Acute and Chronic) 9. 9. 5. 3.9 3. Page

Rate per, population Case Counts Rate by, population Graph. Chronic and Acute Hepatitis B Case Counts and Rates per, in New Brunswick, - 6. 8. 6.... 3 5 6 Hepatitis B(Chronic)-NB-Count. 39. 3. 3. 3. 69. Hepatitis B(Acute)- NB-Count 8. 3.. 9... Hepatits B(Acute)- NB-Rate......3 Hepatits B(Chronic)- NB-Rate 3. 5. 5.7. 5.7 9.. 8. 6.... Graph. Chronic Hepatitis B Case Counts and Incidence Rate per, by Sex and Age groups, New Brunswick, -6 3 5 5 5 < - 5-9 3-39 -59 6+ < - 5-9 3-39 -59 6+ Male Female 6 Count 3 3 9 6 5 9-5 Average Count 5 9 3 5 6 Rate 5..6 3.6..6. 5. 9... 8.8.8-5 Average Rate. 9. 5.3.3 8. 3..8.7 9. 9.5.3.8 Risk Factors Risk factors are only presented for the chronic hepatitis B cases who probably had acquired their infection in Canada (n=5). Some chronic hepatitis B cases were missing information about their risk factors. Nine cases (3% of cases with completed answers) reported living in the same household with other hepatitis B cases. Among those with reported risk factors, all cases identified themselves as heterosexuals. 77% reported not using condoms regularly when performing oral or vaginal sex in the last months. Three cases reported having received blood transfusion (no dates available); five cases underwent surgery (surgery dates ranged from 5 to 5). Seven cases (% of cases with available answer to this question) reported sharing their personal hygiene items with others. These cases might still have acquired their infection outside of Canada; however, this could not be confirmed by the information we are currently collecting. Page

Table. Socio-demographic and behavioral risk factors in male and female chronic hepatitis B cases in New Brunswick, 6. Sociodemographic and behavioral RF Males (N=5) Females (N=) *Not mutually exclusive. Median age in years (range) 3 (-75) 3 (3-7) Reason for testing Symptomatic Routine blood work Pregnancy screening Contact of case Other 6 N/A 3 Co-infection --- Syphilis: Living with a Hepatitis B case in same household Partner Parent Sibling Sharing personal hygiene items with others 6 Sexual orientation Heterosexual Homosexual Bisexual # of sexual partners 3-9 # of cases by type of sexual partners* Regular Casual Anonymous Out of province Practicing oral sex: Yes/Total answered % condom use for oral sex Never Some of the time Every time Practicing vaginal sex: Yes/Total answered % condom use for oral sex Never Some of the time Every time 5 9 9 /3 % % % % 5/6 6% % % % 8 5 7 /3 % % % % /5 5% 5% % 5% Page

Rate per, population Rates per, population D. Hepatitis C Hepatitis C is the most commonly reported blood-borne infection in New Brunswick. i. Overview In 6, the incidence rate of hepatitis C diagnosis was 3.9 cases per, people with 8 cases of hepatitis C reported to Public Health, of which were confirmed new infections (i.e. documented seroconversion to anti-hcv positive in a person who was previously seronegative within the last months). Two-thirds (67%) of all reported cases were males. Forty-three percent of the male cases were among individuals aged 5-39 years old, with the highest incidence in those aged 3 to 3 years old. Among females, 63% of the newly diagnosed cases were aged to 39 years old, with the highest incidence among those in the 35-39 year olds. The number of hepatitis C cases was more or less stable over the last years. More than one third of the cases (35%) were reported in Region, 8% were reported in Region, 7% in Region 3 and 6% in Region 7. Graph. Hepatitis C Incidence Rates per, population Overall and by Sex for New Brunswick and Canada, -6. 35. 3. 5.. 5.. 5.. 3 5 6 NB Rates (Males) 3. 9.6 3. 33. 33.3 3.6 NB Rates (Females).5 7.5. 5.. 5. NB Rates.6 3.5 6.3 3.9 3.6 3.9 Canadian Rates 8.8 9.3 9.6 9. 3. Graph 3. Hepatitis C Case Counts and Incidence Rate per, by Sex and Age groups, New Brunswick, -6. 8. 6.... <5 5-9 - 5-9 3-39 -59 6+ <5 5-9 - 5-9 3-39 -59 6+ Male Female 6 Count 6 33 3 7 3 3 3 5-5 Average Count..8 5. 9. 7.6 3. 9.8. 3. 9.8. 5. 7.6.8 6 Rate. 9.3 6. 7. 73.7 39. 7.8..5 5.8. 5...6-5 Average Rate.. 6. 85.7 6. 38..3. 6. 3.3 5.8 3. 5..8 Page 3

Number of cases Percentage of cases ii. Risk Factors On average, 6% of the cases provided answers to the questions related to risk factors. This percentage was particularly lower for questions related to sexual behavior. Of the cases who provided an answer to whether they were using illicit drugs, 8 cases (9%) answered that they were using drugs with the majority (8 %) using both injection and non-injection drugs. More than half of the cases (5%) reported sharing needles, and around two thirds (66%) shared drug paraphernalia. 7% had tattoos and 5% had body piercings. Thirty-eight percent of cases, with an answer to this question, were admitted to a correctional facility in the previous months. Despite the fact that hepatitis C is mainly a blood born infection and that sexual route does not play a major role in its transmission 3, the prevalence of high-risk sexual behavior was high among our cases. Fourteen percent of the cases had been previously diagnosed with an STI. One fourth of the cases, who provided information on the number of their sexual partners (6% of all cases), reported having or more partners in the last months. Of those who reported practicing oral sex in the last months, 75% were mostly not using condoms. Out of those with completed answer to this question (6% of all cases), 8% reported living with a household member infected with hepatitis C. Prevalence of risk factors among newly infected cases was comparable to the other hepatitis C cases with the exception of the risk factors related to sexual behavior, which was not noted among the newly infected individuals. Graph. Illicit drug use in male and female Hepatitis C cases* in New Brunswick, 6. Graph 5. Needles/paraphernalia sharing in male and female Hepatitis C cases* in New Brunswick, 6. 6 5 3 7 5 8 No drugs Street drugs Injection drugs 56 38 Both street and injection drugs % 8% 6% % % % 53% 8% Sharing needles 69% 63% Sharing paraphernalia Male Female *only cases providing answers are represented 3 Chan DP, Sun HY, Wong HT, Lee SS, Hung CC. Sexually acquired hepatitis C virus infection: a review. Int J Infect Dis. 6;9:7 58. http://www.ijidonline.com/article/s-97(6)373-6/fulltext Page

Table 3. Socio-demographic and behavioral risk factors in male and female hepatitis C cases in New Brunswick, 6. Sociodemographic and behavioral RF Males (N=) Females (N=59) Median age in years (range) 39 (8-75) 35 (7-65) Newly acquired infections 8 3 Reason for testing Symptomatic High-risk behaviour (IVDU) Methadone program screening Pregnancy screening Contact of case Screening in correctional facilities Other 5 9 7 N/A 6 5 38 6 6 5 6 9 3 Co-infection Chlamydia:; Hepatitis B: Chlamydia: Living with a Hepatitis C case in same household Partner Parent Son/Daughter Sibling Roommate Sharing personal hygiene items with others: Yes/total answered /6 7/38 Using illicit drugs : Yes/total answered Street drugs Injection drugs Both 8 7 5 7/76 5 56 6/53 8 38 Shared needles: Yes/total answered 5/7 3/7 Shared paraphernalia: Yes/total answered 5/65 9/6 Admitted to a correctional facility: Yes/total answered 3/65 /39 Sexual orientation Heterosexual Homosexual Bisexual # of sexual partners 3-more than 9 # of cases by type of sexual partners* Regular Casual Anonymous Out of province 6 3 55 36 7 9 59 6 7 3 5 9 3 6 3 8 3 6 Page 5

Sociodemographic and behavioral RF (cont.) Males (N=) Females (N=59) Practicing oral sex: Yes/Total answered % condom use for oral sex Never Some of the time Every time 3/ 58% 3% % 9% /5 /3 5% 3% % % 8/35 Practicing vaginal sex: Yes/Total answered % condom use for oral sex Never % 3% Some of the time 9%.5% Every time %.5% 59% % Practicing anal sex: Yes/Total answered 6/36 5/7 *Not mutually exclusive. E. HIV/AIDS i. HIV Rates for HIV in New Brunswick continue to be well below national rates. In 6, there were seven cases (5 females and males) of newly diagnosed HIV reported to Public Health, with an incidence rate of.9 cases per, people. Four cases (57%) were new immigrants to Canada, and would have acquired the infection prior to their arrival in the country. Among cases who would probably have acquired the infection within Canada (n=3), two were sexual partners and one was an illicit drug user. Among all the cases, three had co-infections: one with hepatitis C, one with hepatitis B and one with both hepatitis B and syphilis. The annual changes in the HIV and AIDS incidence rates should be interpreted with caution; the relatively low number of cases can result in major fluctuations in the rate from year to year. Page 6

Rate per, population Graph 6. HIV and AIDS Case Counts and Incidence Rates per, population for New Brunswick and Canada, -6. 8 6 3 5 6 HIV-NB Count 5 9 7 HIV-NB Rate.3.5.7.5..9 HIV-Canadian Rate 6. 5.9 5.9 5.8 5.9 AIDS-NB Count AIDS-NB Rate..3..3..5 AIDS-Canadian Rate.6.7.9.7 ii. AIDS Rates for AIDS in New Brunswick continue to be well below national rates. In 6, there were four cases ( males and females) of newly diagnosed AIDS reported to Public Health with an incidence rate of.5 cases per, people. All but one were new comers to New Brunswick (whether from another country or another province). The annual changes in the HIV and AIDS incidence rates should be interpreted with caution; the relatively low number of cases can result in major fluctuations in the rate from year to year. F. Infectious Syphilis i. Overview In 6, there were cases of infectious syphilis reported to Public Health with an incidence rate of.8 cases per, people. Cases reported in 6 were the lowest reported since the syphilis outbreak was declared over in early 3. However, most of the cases occurred in the fourth quarter of 6 during which 8 cases (57% of total cases in 6) were reported. Risk factors of cases reported in the first 3 quarters of 6 were comparable to those reported in the last quarter. All but one case reported in 6 were males. Infections primarily occurred among males aged -3 years (86% of all cases). The median age of all cases was 3 years old (range: -7). Cases in the last quarter of 6 were slightly older than those reported in the first three quarters: median age 3 versus years respectively. Most of the cases were reported from Regions (n=6) and 3 (n=5). Page 7

Rate per, population Rates per, population Graph 7. Infectious Syphilis Incidence Rates per, population Overall and by Sex for New Brunswick and Canada, -6. 6.... 8. 6.... 3 5 6 NB Rates (Males) 3..5 8.8 7. 7.5 3.5 NB Rates (Females)...3.3..3 NB Rates 7..8.5 3.6..8 Graph 8. Infectious Syphilis Case Counts and Incidence Rate per, by Sex and Age groups, New Brunswick, -6 3 5 5 5 <5 5-9 - 5-9 3-39 -59 6+ <5 5-9 - 5-9 3-39 -59 6+ Male Female 6 Count 5 5-5 Average Count 7 6 Rate... 9...9......3.. -5 Average Rate. 9.6 7. 7.7 9...8. 3.8.8.9..7. The changes in annual rates for syphilis should be interpreted with caution; low numbers can cause large fluctuations in rates. ii. Risk Factors All the male cases identified themselves as MSM with the most common risk factors reported for syphilis infections being not practicing safe sex and having multiple sexual partners. Among cases reported in 6, 69% of cases did not use a condom while performing oral, vaginal or anal sex in the last months. Never using condoms was higher among those who reported performing rimming (86%) and oral sex (8%) versus those performing anal sex (36%). Thirty-six percent reported having two or three sexual partners, and more than one quarter (7%) reported having five or more sexual partners in the last months, with 6% reporting having casual or anonymous sexual contacts. Half of the cases used illicit drugs, mostly non-injection, in the last months. Three had concurrent coinfection with Page 8

Percentage of cases other STIs ( with chlamydia and with hepatitis B); while four had been previously diagnosed with other STIs ( chlamydia, gonorrhea and syphilis). Graph 9. Condom use among in male cases of infectious syphilis * in New Brunswick, 6. % 8% 6% % % % 8% 36% 36% 9% 8% 9% 9% 86% % Oral sex (n=) Anal sex (n=) Rimming (n=7) condom use Condom use everytime Condom use some time Never use condom *only cases reporting practicing oral, anal sex or rimming are represented Table. Socio-demographic and behavioral risk factors in infectious syphilis male cases in New Brunswick, 6 Sociodemographic and behavioral RF Males (N=3) Median age in years (range) 8 (-7) Reason for testing Symptomatic Routine STI check-up Pregnancy screening N/A Contact of case 5 Other Chlamydia:, Co-infection Hepatitis B: Sexual orientation Heterosexual Homosexual Bisexual # of sexual partners 3-9 #of cases by type of sexual partners* Regular Casual Anonymous Out of province 6 5 3 5 Page 9

Sociodemographic and behavioral RF (cont.) Practicing oral sex: Yes/Total answered % condom use for oral sex Never Some of the time Every time Practicing anal sex: Yes/Total answered % condom use for anal sex Never Some of the time Every time Practicing rimming: Yes/Total answered % condom use with rimming Never Some of the time Every time Males (N=3) / 8% 9% % 9% / 36.5% 36.5% 8% 9% 7/9 86% % % % *Not mutually exclusive. Page

7. Summary and conclusion In 6, higher incidence rates of chlamydia, gonorrhea, chronic and acute hepatitis B, and AIDS were observed compared to the previous 5-year averages. However, incidence rates remained stable for cases of hepatitis C and HIV. Missing information related to the sexual history, drug use history as well other risk factors was noted for some diseases e.g. Hepatitis C and Hepatitis B (both acute and chronic) which did not allow for further analysis and interpretation of patterns of behavior among different age groups. For sexually transmitted infections, all cases reported high-risk sexual behavior, with the most prominent being the practice of unsafe oral sex, in addition to the other types of sex. For blood borne infections, illicit drug use (whether injectable or non-injectable) and sharing needles or paraphernalia was very prominent among the cases. Effective messaging related to practicing safe sex as well as reducing harm while using illicit drugs is crucial to control and prevent STBBIs in New Brunswick. Page

Appendix Map of New Brunswick Health Regions Page

Appendix : STBBIs in New Brunswick in -6 (counts and incidence rates by, population) Sexually Transmitted and Bloodborne Infections NB 3 5 6 N Rate N Rate N Rate N Rate N Rate N Rate AIDS..3..3..5 HIV.3.5 6.8.5 9. 7.9 Chlamydia (genital) 97 53.7 93 55. 767 33.8 738 9.6 88 9. 98 5.8 Gonorrhea (genital) 7 9. 38 5. 7 6. 5.8 5 6.6 73 9.6 Hepatitis B (Acute) 8. 3.. 9...3 Hepatitis B (Chronic) 3. 39 5. 3 5.7 3. 3 5.7 69 9. Hepatitis C 56.6 77 3. 97 6. 8 3.8 78 3.6 8 3.9 Syphilis (Infectious) 58 7.7.8 3.5 7 3.6 3..8 Syphilis (All) 7 9.5 3 5.7 8 6. 6 6. 5 6. 3. Appendix 3: STBBIs in New Brunswick in 6 by Region (counts and incidence rates by, population) Region Region Region 3 Region Region 5 Region 6 Region 7 N Rate N Rate N Rate N Rate N Rate N Rate N Rate N Rate Sexually Transmitted and Bloodborne Infections Chlamydia (genital) 65 35. 33 97.5 588 333.7 8 79. 6 79.8 7 7.3 97. 98 5.8 Gonorrhea (genital) 3. 8..9. 3.9 5 6.6. 73 9.6 Hepatitis B (Acute).7.......3 Hepatitis B (Chronic) 6. 6.3 8 5.9.3..3. 69 9. Hepatitis C 6 9.9 33 9. 3 7. 3 6. 8 3.3 8.6 9 6. 8 3.9 Syphilis (Infectious) 6.8.6 5.8. 3.9.3..8 Syphilis (All) 5.6. 9 5.. 3.9 7 9.3. 3. NB Page 3

Appendix : STBBIs in New Brunswick in 6 by age group and sex (counts and incidence rates by, population) NB Age groups < - 5-9 - 5-9 - 5-9 3-39 -59 6+ N Rate N Rate N Rate N Rate N Rate N Rate N Rate N Rate N Rate N Rate Total Rate Sexually Transmitted and Bloodborne Infections Male.........9..5 AIDS Female........3.9..5 Total.........9.5.5 Male...........5 HIV Female.......8.3 3.6. 5.3 Total.......3. 3.3. 7.9 Male.... 7. 7 3.6 9 673.9 5.5 36.5. 663 77. Chlamydia (genital) Female... 6 33. 389 989. 76 98.3 7 93. 9 9.8 37 3..9 65 33.3 Total... 6 5.9 9 9.3 78 66. 376 876.9 3 58. 77 3..5 98 5.8 Male.... 9.3 6. 63.3 6 3. 7 6...7 Gonorrhea (genital) Female.... 7 35.8 6. 9.3 7 5.8 5.. 33 8.6 Total.... 9.9 6. 8. 3.6 5.. 73 9.6 Male........ 8 7.3..7 Hepatitis B (Acute) Female........... Total........ 8 3.6..3 Male.... 9.3 3.6 3 3.6 9. 6.6. 37 9.9 Hepatitis B (Chronic) Female... 5.5 3 5.3 9. 5. 9. 8.8.8 3 8. Total... 3 8. 5. 5. 8 8.7 8. 6.6. 69 9. Male.... 9.3 6. 6 7. 33 73.7 3 39. 7 7.8 3.6 Hepatitis C Female.....5 5.8 3. 3 5. 3. 5.6 59 5. Total.... 6.6 8. 9.3 56 6.9 56 5..8 8 3.9 Male..... 5. 9. 5..9. 3 3.5 Syphilis (Infectious) Φ Female........3...3 Total..... 5..7 6 6.7...8 Male..... 7 9. 3 3.6 8 7.9.9. 3 6. Syphilis (All) Female...... 9.6 9..8. 8. Total..... 7 5. 5.7 3.5 3.3. 3. Page