Contraception for Adolescents: What s New?

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Contraception for Adolescents: What s New? US Medical Eligibility Criteria for Contraceptive Use Kathryn M. Curtis, PhD Division of Reproductive Health, CDC Expanding Our Experience and Expertise: Implementing Teenage Pregnancy Prevention Programs March 12-14, 2012 Baltimore, MD National Center for Chronic Disease Prevention and Health Promotion Division of Reproductive Health

Objectives Understand trends in teen pregnancy and contraceptive use Describe the current evidence-based recommendations about the safety of contraceptive methods for teens Describe current contraceptive methods available to teens, including LARCs

Pregnancy, birth and abortion rates for teens 15-19 years Kost et al., Guttmacher Institute 2012

Most teens use contraception: Use among sexually experienced females 15-19 years

Use of contraception at first sex among females 15-19 years

So why are teen pregnancy rates so high? 46% due to non-use of contraception 54% due to contraceptive failure Effectiveness of method Consistent and correct use Santelli et al., 2006

Typical Effectiveness of Family Planning Methods Long acting reversible contraceptives (LARCs) Tier 1 Tier 2 Tier 3 Tier 4 Adapted from: WHO. Family Planning: A Global Handbook

Long Acting Reversible Contraception (LARC) Forgettable contraception Not dependent on compliance/adherence Available in US: IUDs: copper and hormonal Implant expanding access to LARC for young women has been declared a national priority (IOM) Encourage implants and IUDs for all appropriate candidates, including nulliparous women and adolescents. (ACOG 2009)

Method choice Use of contraception at last sex among females ages 15-19, who had sex in the last 3 months, 2006-2010 Method % Any method 86 Condoms (Tier 3) 52 Pills (Tier 2) 31 Other hormonals (Tier 1-2) 12 Other methods (Tier 1-4) 11 No method 17 Martinez et al., Vital Health Stat 23(31), 2011.

Contraceptive Methods for Adolescents: What s New? US Medical Eligibility Criteria for Contraceptive Methods Contraceptive methods and adolescents

U.S. Medical Eligibility Criteria for Contraceptive Use (MEC)

US MEC Evidence-based recommendations on the use of contraceptive methods among women with medical conditions or other characteristics (age) Adapted from global guidance, World Health Organization Purpose of recommendations: To assist health care providers in counseling about contraceptive method choice To serve as source of clinical guidance Health care providers should always consider individual clinical circumstances

MEC Categories 1. A condition for which there is no restriction for the use of the contraceptive method. 2. A condition where the advantages of using the method generally outweigh the theoretical or proven risks. 3. A condition where the theoretical or proven risks usually outweigh the advantages of using the method. 4. A condition which represents an unacceptable health risk if the contraceptive method is used.

Smoking and Contraceptive Use CONDITION CHC POP DMPA IMP Cu-IUD LNG-IUD SMOKING a) Age<35 2 1 1 1 1 1 b) Age>35 (i) <15 cigarettes/day 3 1 1 1 1 1 (ii) >15 cigarettes/day 4 1 1 1 1 1

Summary of MEC by age Method COC, Patch, Ring POP Implant Barrier Injection IUD Age < 40 All ages All ages All ages <18 < 20 MEC 1 1 1 1 2 2 1 No restriction 2 Generally can use 3 Generally do not use 4 Do not use

Tier 1 Methods Very Effective Levonorgestrel-releasing intrauterine system Copper IUD Implant

Levonorgestrel-releasing intrauterine system (IUS) Effective for at least 5 years Side effects: irregular bleeding US MEC For ages < 20: 2 For nulliparous women: 2 For increased risk of STIs: 2/3 Does not protect against sexually transmitted infections (STIs)

Copper intrauterine device (IUD) Effective for at least 12 years Side effects: irregular bleeding, heavy bleeding US MEC For ages < 20: 2 For nulliparous women: 2 For increased risk of STIs: 2/3 Does not protect against STIs

Contraceptive implant Effective for at least 3 years Side effects: irregular bleeding US MEC for all ages: 1 Does not protect against STIs

Injectable (DMPA) Pill Patch Ring Tier 2 Methods Effective

Contraceptive injection: Depo medroxyprogesterone acetate (DMPA) One injection every 3 months Reliable contraception for 3 months, but effects may last up to 9 months Side effects: irregular bleeding US MEC for ages < 18: 2 Bone mineral density Weight Does not protect against STIs

Contraceptive pills Combined pills contain estrogen and progestin US MEC for age < 40: 1 Side effects: hormone-related side effects Progestin-only pills contain only progestin US MEC 1 for all ages Side effects: irregular bleeding Do not protect against STIs

Contraceptive patch Releases estrogen and progestin, so similar to combined pills One patch per week for 3 weeks, then 1 patch-free week Side effects: similar to COCs US MEC for age < 40: 1 Does not protect against STIs

Contraceptive vaginal ring Releases estrogen and progestin, so similar to combined pills One ring for 3 weeks, then 1 ring-free week Side effects: similar to COCs US MEC for age < 40: 1 Does not protect against STIs

Tier 3 Moderately Effective Condoms (male and female) Diaphragms, cervical cap, sponge Fertility awareness-based methods

Tier 4 Less Effective Withdrawal Spermicides

DUAL PROTECTION

Condoms US MEC for all ages: 1 Male latex condoms reduce risk of STIs, including HIV, when used correctly and consistently

Chlamydia Age- and sex-specific rates: United States, 2008 Men Rate (per 100,000 population) Women 3500 2800 2100 1400 700 0 Age 0 700 1400 2100 2800 3500 CDC, 2008 10-14 15-19 20-24 25-29 30-34 35-39 13.9 129.9 701.6 3275.8 1056.1 3179.9 565.9 1240.6 271.7 498.9 140.8 205.6 78.3 40-44 85.8 34.4 45-54 30.9 10.4 8.4 55-64 2.7 2.1 65+ Total 211.7 585.6

Dual Protection Use of dual methods (condom and hormonal method) among 15-19 year olds, who had sex in 3 months prior to interview 40 35 30 25 20 15 10 Females Males 5 0 1995 2002 2006-10 Abma et al., NSFG, 2010.

Emergency contraceptive pills Take up to 120 hours after unprotected sex Current products: levonorgestrel Without prescription: ages 17+ Prescription: ages < 17 New formulation: ulipristal acetate Marketed in late 2011 May be more effective than levonorgestrel beyond 48 hours Prescription only

Take Home Messages Rates of adolescent pregnancy in the US are decreasing, but remain high Adolescents who are at risk of unintended pregnancy need access to highly effective contraceptive methods Adolescents are eligible to use all methods of contraception there is no contraceptive method that an adolescent cannot use based on age alone Long-acting, reversible contraception (LARCs) may be particularly suitable for many adolescents IUDs Implants Dual protection should be encouraged among adolescents

Resources US MEC published in CDC s Morbidity and Mortality Weekly Report (MMWR): http://www.cdc.gov/mmwr/preview/mmwrhtml/rr5904a1.htm?s_cid =rr5904a1_w CDC evidence-based family planning guidance documents: http://www.cdc.gov/reproductivehealth/unintendedpregnancy/usm EC.htm

Use of trade names and commercial sources is for identification only and does not imply endorsement by the US Department of Health and Human Services. The findings and conclusions in this presentation have not been formally disseminated by the Centers for Disease Control and Prevention and should not be construed to represent any agency determination or policy.