Hompes Method Prac00oner Training Level II Lesson Forty Eight PMS, PCOS, Menopause Health for the People Ltd not for reuse without expressed permission Hompes Method is a trading name of Health For The People L< Registered in England & Wales Company # 6955670 VAT # 997294742
PMS: premenstrual syndrome A ra4 of symptoms associated with luteal phase imbalances: Low progesterone (mostly) Estrogen dominance Possibly the sudden drop in hormones before period En=re luteal phase, or just a few days Very common Believed to be normal or worse, all in your head
PMS: premenstrual syndrome Up to 80% women report having some symptoms prior to menstruayon. These symptoms qualify as PMS in 20 to 30% of premenopausal women. haps://en.wikipedia.org/wiki/premenstrual_syndrome
hap://www.mygynae.co.uk/tag/premenstrual-syndrome/
PMS: premenstrual syndrome Estrogen too high? Food Blood sugar imbalances High insulin Alcohol (aromatase) Estrogenic toxins Cosme=cs? Pes=cides? The pill, injec=on, patch NOTE: estrogen may be too low in follicular phase and not trigger ovula=on, thus leading to low progesterone (high insulin can cause this). Progesterone too low? Food Nutrient deficiencies Blood sugar imbalances Circadian rhythm Emo=onal stress Inflamma=on (GI, liver) Low T3 Anything that s=mulates the HPA axis Each molecule of cor=sol is made from a molecule of progesterone
PMDD premenstrual dysphoric disorder Premenstrual dysphoric disorder (PMDD) is a severe and disabling form of premenstrual syndrome affecyng 3 8% of menstrua0ng women. [3] The disorder consists of a "cluster of affecyve, behavioral and somayc symptoms" that recur monthly during the luteal phase of the menstrual cycle. [3] haps://en.wikipedia.org/wiki/premenstrual_dysphoric_disorder
Key PMS symptoms Mood changes: Altered sex hormone levels Possible interac=ons of these hormones with neurotransmiaers Progesterone calms an=-anxiety Estrogen an=-depression Testosterone pro-irritable/aggression
Key PMS symptoms Fibrocys=c breasts: Tissue that feels lumpy or rope-like in texture Tenderness, nipple discharge Usually luteal phase Generally related to unchecked estrogen, i.e. not enough progesterone Possible iodine deficiency, which increases =ssue sensi=vity to estrogen
Key PMS symptoms Bloa=ng/weight gain: Unchecked estrogen causes water reten=on (i.e. elevated estrogen, or low progesterone) May be worse when aldosterone is also imbalanced (high aldosterone due to stress reduces water excre=on)
Key PMS symptoms Menstrual cramps: Uterine lining tears away because the hormone balance is not op=mal to enable smooth shedding (especially progesterone)
Key PMS symptoms Cyclical headaches/migraines: Could be a sudden drop in estrogen and / or progesterone at the onset of period Could be normal prostaglandin release at onset of period Possible role for omega-3/6 therapy May also be related to magnesium, electrolyte, B6 status B6 deficiency can masquerade as omega-3 deficiency (Ray Peat) May even be related to H. pylori or possibly other infec=ons
Key PMS symptoms Acne/oily skin: Elevated androgens Possibly due to insulin-gene=c combina=on Stress Androgens may increase if estrogen and progesterone are low (have seen skin issues clear up on suppor=ng estrogen)
Key PMS symptoms Fa=gue Estrogen dominance (suppresses energy produc=on and thyroid func=on) Low progesterone (progesterone is pro-metabolic) Obvious interac=ons with between HPA, HPT and HPG
Are PMD and PMDD normal? If they were normal, why do some women not have any symptoms? God did not create women to live in pain ~ Prof. Rebecca Murray
PCOS: polycys=c ovary/ovaries syndrome PCOS is caused by anovula=on The forma=on of cysts in the ovary due to the lack of ovula=on. The cysts accumulate like a string of pearls haps://www.researchgate.net/publica=on/ 264813715_Automated_ovarian_classifica=on _in_digital_ultrasound_images
PCOS: polycys=c ovary/ovaries syndrome haps://www.indiasopinion.in/polycys=covarian-syndrome-epidemic-in-india/
PCOS: polycys=c ovary/ovaries syndrome What causes anovula=on? Insulin messes up the FSH:LH ra=o LH: FSH ra=o usually 1:1 A surge of LH mid-cycle induces ovula=on and release of the follicle When there is a chronically elevated LH:FSH ra=o, slight rise in LH does not s=mulate ovula=on
PCOS: polycys=c ovary/ovaries syndrome
PCOS: polycys=c ovary/ovaries syndrome Common symptoms on the PCOS spectrum: Irregular menses PMS symptoms Heavy periods with clots Acne (improves with BCPs) / history of acne Hirsu=sm (hidden a4er laser treatment) Nega=ve ovulatory tests despite having periods Acanthosis nigricans Increasing abdominal girth Inability to lose weight Difficulty conceiving
PCOS Diagnosis NIH (Na=onal Ins=tutes for Health): Hyperandrogenism and oligomenorrhoea (no ovarian ultrasound US) RoAerdam consensus 2003 - any two of these three: Hyperandrogenism Oligomenorrhoea Ovarian ultrasound demonstra=ng mul=ple superficial small cysts (< 10mm) Androgen Excess Society 2006: Hyperandrogenism AND oligomenorrhoea OR String of pearls PCOS
Why insulin is so important - cancer
Why insulin is so important - cancer
From PMS to perimenopause According to Dr. Uzzi Reiss, while PMS is associated with low progesterone, symptoms of perimenopause are associated more with lower estrogen. Hot flushes Foggy thinking Low sex drive Vaginal dryness Painful intercourse UTI Dry skin/thinning skin
From perimenopause to menopause Key considera=ons: Are symptoms more related to: Low progesterone Estrogen dominance Low estrogen Low androgens High androgens Thyroid Adrenals
From perimenopause to menopause Estrogen declines significantly Depression, brain fog, vaginal/sexual, UTI, thin skin, flushes Progesterone declines even more Anxiety, fa=gue, insomnia, weight gain, bloa=ng Androgens decline significantly Low sex drive, muscle weakness, fa=gue, poor memory Adrenals have to take up the slack Thyroid is significantly affected by other hormones If there isn t enough T3, however, the steroid cascade won t funcyon opymally
It s confusing I don t blame you if you re a liale confused I was. There s so much to learn with the hormones, paaerns and pathways. Let s begin to simplify things
Introduc=on to hormone assessment Hormone assessment isn t that difficult: Assess symptoms Use symptom lists (provided separately) Assess history Big clues: Chemical contracep=on Use labs Hysterectomy Miscarriages, fer=lity, etc. Serum, dried urine, saliva
Summary PMS and PMDD are very common and are usually down to low progesterone (absolute or rela=ve) PCOS is a partly gene=c, mostly insulin related disorder that messes up FSH/LH and causes anovula=on Perimenopause is o4en related to declining estrogen. Several paaerns can play a role a4er menopause. Adrenals and thyroid are o4en involved (you could reasonably assume they are always involved)
Thanks and next up Thanks for watching or listening. Next up, we re going to look at men for a change: it won t take long as we re fairly simple J