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Instructions for completing orders Complete pages 1-3 for General Inpatient Orders. All pathway compatible orders (indicated by ) within the General Inpatient Orders will be followed automatically. Optional orders (indicated by ) can be given by selecting the corresponding check boxes. To cancel pre-selected orders, strike through and initial. Determine entry phase on admission as per the AHS Pediatric Asthma Clinical Pathway for Inpatient Care and complete orders for entry into Phase I (page 4) or Phase II (page 6). Complete orders for each subsequent phase when patient is ready to be moved from Phase I to II, or from Phase II to III. General Inpatient Orders (page 1 of 3) Admit to hospital Diagnosis: Status Asthmaticus Isolation: Droplet and contact isolation Determine height and weight on admission Height cm Weight kg Diet: Clear fluids while in Phase I, diet as tolerated once in Phase II and III Monitor intake and output, q8h Vital signs: respiratory rate, heart rate with each modified PRAM assessment, blood pressure q4h, O 2 saturation q4h and PRN before each dose of salbutamol, temperature q4h Asthma education: Arrange for asthma education. (Best done in Phase II or III) Referrals: Social Work referral Respiratory Therapy referral Investigations (indicate timing for labs) (Continued on next page) Complete Blood Count (CBC) Creatinine Electrolytes (Na, K, Cl, CO 2 ) Glucose Random Urea Page 1 of 8

General Inpatient Orders (page 2 of 3) Investigations (continued) Bedside spirometry (pre-bronchodilators) once daily, in patients greater than or equal to age 6 Physician: Please ensure the Patient is well enough to do a 10 sec breath hold, repeatable Vital Capacity maneuvers and tolerate being off O 2 for up to 30 min. Testing will only be performed on patients who are not on ISOLATION and are negative for TB TESTING. Oral/IV corticosteroids PredniSONE/prednisoLONE liquid mg PO daily for 5 days. (Recommended dosing 1-2 mg/kg/day. Max dose 60 mg) PredniSONE tab mg PO daily for 5 days. (Recommended dosing 1-2 mg/kg/day. Max dose 60 mg) Dexamethasone liquid mg PO, daily for days. (Recommended dosing 0.15-0.3 mg/kg/dose. Max dose 10 mg) Consider if emesis with prednisone MethylPREDNISolone IV mg loading dose once if loading dose is not already given in ED. (Only if patient is not tolerating oral). (Recommended loading dose 2 mg/kg. Max 80 mg/dose for load) MethylPREDNISolone IV mg q6h. (Only if patient not tolerating oral; assumes loading dose has been given prior.) (Recommended maintenance dose 1 mg/kg/day. Max 80 mg/day for maintenance) Inhaled corticosteroids Beclomethasone inhaler, puffs bid. (100 microgram per puff; usual dosing 2 puffs) Fluticasone inhaler, puffs bid. (125 microgram per puff; usual dosing 2 puffs) Fluticasone Diskus, puffs bid. (250 microgram per puff; usual dosing 1 puff) Budesonide Turbuhaler, puffs bid. (200 microgram per puff; usual dosing 2 puffs) Ciclesonide inhaler, puffs daily. (100 microgram per puff; usual dosing 1 puff) Ciclesonide inhaler, puffs daily. (200 microgram per puff; usual dosing 1-2 puffs) Ciclesonide inhaler, puffs bid. (100 microgram per puff; usual dosing 1 puff) Ciclesonide inhaler, puffs bid. (200 microgram per puff; usual dosing 1-2 puffs) Maintenance Therapy (continued on next page) If patient is less than 6 years of age, montelukast CHEW tab, 4 mg PO, qhs If patient is 6-14 years of age, montelukast CHEW tab, 5 mg PO, qhs If patient is greater than 14 years of age, montelukast tab, 10 mg PO, qhs Page 2 of 8

General Inpatient Orders (page 3 of 3) Maintenance Therapy (continued) ADVAIR inhaler puffs bid. (Contains Fluticasone 125 microgram + Salmeterol 25 microgram per puff) ADVAIR Diskus puffs bid. (Contains Fluticasone 250 microgram + Salmeterol 50 microgram per puff) (Max suggested dose 1 puff bid due to Salmeterol dosing) SYMBICORT Turbuhaler puffs bid. (Contains Budesonide 100 microgram + Formoterol 6 microgram per puff) SYMBICORT Turbuhaler puffs bid. (Contains Budesonide 200 microgram + Formoterol 6 microgram per puff) IV Fluids Bolus 0.9% sodium CHLORIDE bolus infusion IV via peripheral line, 10 ml/kg once as fast as possible 0.9% sodium CHLORIDE bolus infusion IV via peripheral line, 20 ml/kg once as fast as possible IV Fluids Infusion D5W-0.45% sodium CHLORIDE with 20 mmol potassium CHLORIDE/Liter at ml/h IV via peripheral line D5W-0.45% sodium CHLORIDE with 40 mmol potassium CHLORIDE/Liter at ml/h IV via peripheral line D5NS with 20 mmol potassium CHLORIDE/Liter at ml/h IV via peripheral line D5NS with 40 mmol potassium CHLORIDE/Liter at ml/h IV via peripheral line Page 3 of 8

Phase I Orders Admit into Phase I of AHS Pediatric Asthma Clinical Pathway for Inpatient Care All orders that are pathway compatible (indicated by ) will be followed automatically. Optional orders (indicated by ) can be given by selecting the corresponding check boxes. To cancel orders, strike through and initial. Assessment by modified PRAM score q30min to q1h as per pathway; modified PRAM assessment 15 minutes post each dosing of salbutamol as per pathway O 2 Therapy (Titrate to Saturation) Maintain SpO 2 at 93%. If O 2 requirements are rising rapidly, please call the physician Continuous oxygen saturation monitoring CardioRespiratory monitor with central monitoring; reassess after 24 hours Salbutamol inhaler via MDI/Spacer Salbutamol solution via nebulizer via oxygen If less than 20 kg, 5 puffs q30-60min PRN as per Phase I of Asthma Pathway If 20 kg or greater, 10 puffs q30-60min PRN as per Phase I of Asthma Pathway If less than 20 kg, 2.5 mg q30-60min PRN as per Phase I of Asthma Pathway If 20 kg or greater, 5 mg q30-60min PRN as per Phase I of Asthma Pathway Once modified PRAM score is less than 3 when assessed 1 hour after last salbutamol, or if in Phase I for 6 hours, call MD to consider transfer to Phase II Page 4 of 8

Orders if patient is clinically deteriorating while in Phase I Chest X-ray, AP and Lateral STAT Chest X-ray, PA portable STAT Capillary blood gas, once, STAT on current therapy Venous blood gas, once, STAT on current therapy Arterial blood gas, once from radial artery, STAT on current therapy Salbutamol inhaler via MDI/Spacer Salbutamol solution via nebulizer Continuous salbutamol solution via nebulizer via oxygen If less than 20 kg, 5 puffs q20min, times 3 doses If 20 kg or greater, 10 puffs q20min, times 3 doses If less than 20 kg, 2.5 mg in 3 ml saline via oxygen q20min, times 3 doses If 20 kg or greater, 5 mg in 3 ml saline via oxygen q20min, times 3 doses If less than 20 kg, 2.5 mg in 3 ml saline via oxygen If 20 kg or greater, 5 mg in 3 ml saline via oxygen Ipratropium inhaler via MDI/Spacer, 4 puffs q20min, times 3 doses with salbutamol Ipratropium solution via nebulizer via oxygen, 250 mcg q20min, times 3 doses with salbutamol MethylPREDNISolone Na succinate mg IV injection, once. (Recommended 2 mg/kg loading dose, max 80 mg/dose) MethylPREDNISolone Na succinate mg IV injection, q6h. Start 6h after loading dose. (Recommended 1 mg/kg/day, max 80 mg/day) Magnesium SULPHATE mg IV bolus injection over 20 minutes. (Dosing 40 mg/k/dose over 20 minutes; max 2000 mg) Cardiorespiratory monitoring recommended 0.9% sodium CHLORIDE bolus infusion via peripheral line, 10 ml/kg as fast as possible 0.9% sodium CHLORIDE bolus infusion via peripheral line, 20 ml/kg as fast as possible Page 5 of 8

Phase II Orders Admit / Transfer into Phase II of AHS Pediatric Asthma Clinical Pathway for Inpatient Care All pathway compatible orders (indicated by ) within this order will be followed automatically. Optional orders (indicated by ) can be given by selecting the corresponding check boxes. To cancel pre-selected orders, strike through and initial. Assessment by modified PRAM score q1h to q2h as per pathway; modified PRAM assessment 15 minutes post each dosing of salbutamol as per pathway O 2 Therapy (Titrate to Saturation) Maintain SpO 2 at 93%. If O 2 requirements are rising rapidly, please call the physician Salbutamol inhaler via MDI/Spacer Salbutamol solution via nebulizer via oxygen If less than 20 kg, 5 puffs q1-2h PRN as per Phase II of Asthma Pathway If 20 kg or greater, 10 puffs q1-2h PRN as per Phase II of Asthma Pathway If less than 20 kg, 2.5 mg q1-2h PRN as per Phase II of Asthma Pathway If 20 kg or greater, 5 mg q1-2h PRN as per Phase II of Asthma Pathway based on modified PRAM score Once in Phase II for 4 hours and modified PRAM score is less than 3 on assessement 2 hours after last salbutamol, and respiratory rate and O 2 needs are stable, RN/RT may direct transfer to Phase III. If modified PRAM score is less than 3 on assessment 2 hours after last salbutamol but directed transfer criteria are not met or patient has been in Phase II for 24 hours, call MD to consider transfer to Phase III. Return to Phase I of Asthma Pathway. Please use a new set of Phase I orders. Page 6 of 8

Phase III Orders Transfer to Phase III of AHS Pediatric Asthma Clinical Pathway for Inpatient Care All orders that are pathway compatible (indicated by ) will be followed automatically. Optional orders (indicated by ) can be given by selecting the corresponding check boxes. To cancel orders, strike through and initial. Assessment by modified PRAM score q4h as per pathway; modified PRAM assessment 15 minutes post each dosing of salbutamol as per pathway O 2 Therapy (Titrate to Saturation) Maintain SpO 2 at 90%. If O 2 requirements are rising rapidly, please call the physician Salbutamol inhaler via MDI/Spacer 5 puffs q4h as per Phase III of Asthma Pathway based on modified PRAM score Salbutamol solution via nebulizer via oxygen 2.5 mg q4h as per Phase III of Asthma Pathway based on modified PRAM score Consider using patient s usual home therapy for B 2 agonist [specify here] puffs q4h as per Phase III of Asthma Pathway. Salbutamol Diskus and Terbutaline Turbuhaler may be used in Phase III instead of Salbutamol MDI if the patient will be using a dry powder inhaler at home; dosing equivalency is 1 dose Salbutamol Diskus = 2 doses Salbutamol MDI 1 dose Terbutaline Turbuhaler = 2 doses Salbutamol MDI Return to Phase II of Asthma Pathway. Please use a new set of Phase II orders. Page 7 of 8

Discharge Instructions Follow up: MD: Refer for further asthma education: Give Childhood Asthma Essentials handout to family If site does not have a mandated medicine reconcilliation process, complete Pediatric Asthma Discharge Prescription and Short-Term Plan, give to family and fax to: MD: Page 8 of 8