August NHS could save 517.6m. Diabetes is on the rise.

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August 2017 Monthly service Commercial bulletin Special points of interest: This bulletin is free to Interested people in Pharma & Healthcare Please send names of new subscribers to Jackie@wavedata.co.uk If you have articles, comments or story ideas, please send them to the email above www.wavedata.co.uk Inside this issue NHS could save 517.6m Pharmacy Show and CPHI Diabetes is on the rise Are you comfortable speaking in public? Cancer drugs now approved for routine use Price Watch UK - Quetiapine rises take over from olanzapine Forthcoming Conferences and events WaveData Top ten searched products where the focus was to August 2017 NHS could save 517.6m A scheme that was launched back in 2011 by the Department of health to help patients stick to their drug routines has been so successful, that the NHS England will save 517.6m in the first 5 years. A Lead researcher from the University of Manchester says that the New Medicine Service, a free scheme where community pharmacists help patients take new medicines - has improved medicines adherence by 10%. Even in the short term, say the team, the scheme where pharmacists are paid 24.60 each time they look after a patient as part of NMS has saved the NHS 75.4m. The team used self-reported adherence at 10 weeks, considered the minimum time required to demonstrate behavioral change in a sample of 503 patients. http://www.manchester.ac.uk/discover/news/pharmacy-service-will-save-nhs-5176m-finds-study/ Pharmacy Show and CPHI Our MD Charles Joynson will be exhibiting at the Pharmacy Show on 8 th and 9 th October, and will be visiting CPHI this year in Frankfurt on the 24 th and 25 th October. Please let him know if you d like to meet up by emailing info@wavedata.co.uk Diabetes is on the rise According to new figures diabetic medicine usage is exceeding the rise in overall prescribing. The figures show that prescription items for the treatment of diabetes in primary care have rocketed 80.1 percent over the last decade, compared with a 46 percent rise across all primary care prescribing. The number of people diagnosed with diabetes has risen by 54 percent in the last decade. http://practicebusiness.co.uk/diabetes-prescriptions-rocket-80-in-a-decade/ Please contact me if you would like to add or suggest any articles/comments for the next issue

Page 2 Newsletter Title Are you comfortable speaking in public? The answer is that many people aren't and that it can cause serious damage to their careers. For many people is even more frightening than bungee jumping or swimming with sharks. There are courses run by professional trainers which can help, but they can be very expensive and fail to deal with the underling fear. Like most phobias the only answer is repeated exposure over long periods, which is exactly what the Toastmasters organisation was set up to do. Toastmasters was set up by an America Ralph C. Smedley in 1905 to help people learn how to speak, conduct meetings, plan programs and work on committees. Since then it has expanded to over 15,000 voluntary clubs and 370,000 members around the world. Clubs hold meetings every couple of weeks, generally in the evenings and work through a standard programme which helps people become familiar with speaking in public. Visitors are welcome and are only asked to join once they begin to find the meetings helpful. Additionally visitors do not need to speak at their first meeting and may prefer to remain silent as they become familiar with how the club works. The process of becoming comfortable with public speaking may take months or years, and is run at the speaker's speed, so there is no need to feel pressured to 'perform'. To find a club in your area and begin making yourself promotable, please visit https://www.toastmasters.org/find-a-club Cancer drugs now approved for routine use Three quarters of the drug s use in the cancer care fund have now been approved for routine use by the National Institute for Health and Care Excellence (NICE). The CDF was established by the government in 2010 as a temporary solution to help patients access cancer drugs that were not widely available on the NHS. However, the fund quickly exceeded its budget, and in 2016 reforms were put in place which required NICE to carry out appraisals for the drugs in the existing fund and all newly licensed cancer drugs. https://www.nice.org.uk/news/article/patients-getting-faster-access-to-cancer-drugs-as-nice-approves-three-quarters-of-the-cancer-drugs-fund

Page 3 Forthcoming events Organizer Date Venue Link or Email Findacure is hosting 'The Cambridge Rare Disease Showcase' 24th Aug 17 Symposium on Trial Design in Rare Diseases - Asterix End Symposium 18th - 19th Cambridge Netherlands https://www.eventbrite.co.uk/e/the-cambridge-rare-disease-showcase-tickets- 35405225984 EMIG Quarterly Meeting 4th http://www.delegant.co.uk/emig/ EMIG Wales 6th Gwent QuintilesIMS Event 'The Future of Pharma and Life Sciences in the UK 7th http://www.cvent.com/events/question-time-the-future-of-pharma-and-life-sciencesin-the-uk/event-summary-218eb8ed4ca14284a0fb033cfb359538.aspx EMIG HR Group 12th EMIG Scotland 14th Scottish Medicines Consortium (SMC) Industry Engagement Event 20th Glasgow https://www.eventbrite.com/e/smc-industry-engagement-event-tickets-32254908299 Mental Health 2017 20th http://mentalhealth2017.govconnect.org.uk/index.php?option=com_reg EMIG Market Access Group 21st 13th Pharmacovigilance 2017 (Conference) 27th - 28th USA saket (a/t) viconferences.co.uk XIII International Pharma Licensing Symposium International Health Partners - Request for Assistance + Free Sharing Best Practice in Product Donations workshop 28th - 29th 3rd Oct 17 Madrid www.plg-group.com/events/xiii-ipls-madrid https://drive.google.com/file/d/0b1-7ji8sxrzpa1v0u0lsdgjvtms/view EMIG Regulatory, Safety & Quality Group Source Transfers, with TRAC Services 11th Oct 17 Delivering the Long-term Sustainability of the NHS, Policy-UK Forum 11th Oct 17 http://policy-uk.com/booking/2531/?g=2937443 A Global Gathering of Supply Chain Experts 16th - 17th Geneva meetings (a/t) hda.org EMIG BD meeting 19th Oct 17 Oxfordshire Next steps for eye care services and treating visual impairment: quality, innovation and STPs Morning 24th Oct 17 Next steps for delivering the new models of care and vanguard sites 25th Oct 17 http://www.westminsterforumprojects.co.uk/book/new-models-of-care-2017 Competitive/Market Intelligence Basics 26th - 27th Oct 17 https://www.researchandmarkets.com/publication/msc83wg/4367994 EMIG Regulatory, Safety & Quality Group 1st Nov 17 Asian Pharma Packaging Conference 2nd - 3rd Nov 17 India pwaghmare (a/t) acieu.net EMIG Quarterly Meeting 6th Nov 17 EMIG Parliamentary Dinnner 6th Nov 17 Conference on corporate governance - shareholder influence, boardroom composition & reform options - keynote: Financial Reporting Council - Westminster 7th Nov 17 http://www.westminsterforumprojects.co.uk/book/corporate-governance-2017 Priorities for primary care in Northern Ireland 8th Nov 17 Belfast http://www.policyforumforni.co.uk/book/primary-care-in-northern-ireland-2017 Action Duchenne Annual Conference 10th - 12th Nov 17 Birmingham Statistics Fundamentals for Clinical Trials for Non- Statisticians (or How to speak stats in a day! ) 14th Nov 17 Reading http://www.psiweb.org/events/psi-events/2017/11/14/default-calendar/statisticsfundamentals-for-clinical-trials-for-non-statisticians-(or-how-to-speak-stats-in-a-day!-)

Monthly service Page 4 Organizer Date Venue Link or Email Policy conference on specialised services and commissioning - discussion relevant to pharmaceutical industry - contributions from NHS England South, NAO, ABPI and Muscular Dystrophy UK 15th Nov 17 http://www.westminsterforumprojects.co.uk/book/specialised-commissioning-17 Next steps for health and social care in Greater Manchester: collaboration, innovation and the future for devolved 22nd Nov 17 Manchester http://www.westminsterforumprojects.co.uk/book/health-and-social-care-in- Manchester-2017 Conference on the reform of healthcare in Ireland 23rd Nov 17 Ireland http://www.policyforumforireland.com/book/healthcare-in-ireland-2017 priorities for the NHS in Scotland - keynotes: The Scottish Government, BMA Scottish Council and NHS National 23rd Nov 17 Central http://www.scotlandpolicyconferences.co.uk/book/nhs-spc-17 Beyond 2019: UK Trade in Goods Post-Brexit 28th Nov 17 http://www.policy-uk.com/booking/2728/?g=2937443 EMIG Scotland 30th Nov 17 EMIG HR Group 5th Dec 17 EMIG Wales 5th Dec 17 Gwent EMIG N Ireland Group Metting 6th Dec 17 Belfast EMIG Market Access Group 7th Dec 17 Christmas Networking Drinks Reception 7th Dec 17 The future for general practice in England 7th Dec 17 http://www.westminsterforumprojects.co.uk/book/general-practice-17 EMIG BD meeting 14th Dec 17 Oxfordshire Policy conference on personalised and genomic medicine 14th Dec 17 http://www.westminsterforumprojects.co.uk/book/personalised-medicine-andgenomics Policy conference on the future of NICE in health and social care - relevant for data and digital technology - with 11th Jan 18 http://www.westminsterforumprojects.co.uk/book/nice-2018 Dementia 2020 The Next Phase 17th Apr 18 http://2018.dementia2020.co.uk/agenda Price Watch UK Quetiapine rises take over from olanzapine Quetiapine was not on the list of price concessions to pharmacists in June. Pharmacists were not compensated for dispensing products whose prices had risen far above those in the Drug Tariff of reimbursement prices. All the talk was of olanzapine, whose June price increases dominated Figure 2 last month, reaching over 1,000% in the case of olanzapine 20mg (Generics bulletin, 14 July 2017, page 14). To see more go to http://www.wavedata.co.uk/newinfo.asp and view our article from this month s Generics Bulletin. WaveData Subscribe to the industry's comprehensive source of news and analysis. www.generics-bulletin.com

WaveData Top ten searched products where the focus was to August 2017 According to WaveData, these were the most commonly investigated products in searches of the online pricing data Wavedata Live at http://www.wavedata.net Both uk and pi prices were viewed for each product, giving some indication of where the focus was to August 2017 WaveData prices in the top 10 article are averages. Product 17-May 17-Jun 17-Jul 17-Aug Gabapen n Caps 300mg 100 2.16 2.17 2.73 7.08 Pregabalin Caps 75mg 56 6.00 4.63 12.62 11.94 Carbocisteine Caps 375mg 120 7.27 6.22 5.52 5.06 Prednisolone Soluble Tabs 5mg 30 44.83 39.89 36.96 32.41 Januvia Tabs 100mg 28 30.71 30.85 30.59 31.67 Olanzapine Tabs 10mg 28 15.93 65.46 67.15 60.22 Leve racetam Tabs 250mg 60 3.33 3.04 11.35 22.35 Citalopram Tabs 20mg 28 0.24 0.25 0.48 0.83 Sumatriptan Tabs 50mg 6 11.73 27.58 26.67 23.33 Hydrocor sone Tabs 10mg 30 39.62 36.01 32.51 32.95 This bulletin now goes out to 4800 plus people. If you would like to add or suggest any articles/comments, please let me know by the 20th September 2017, as I will be issuing the next bulletin on the 27th September 2017 If you have any colleagues who would like to receive this, please let them know about it. You can view all copies of the Bulletin at http://www.wavedata.co.uk/newinfo.asp Jackie Moss WaveData Ltd E-mail: Jackie@wavedata.co.uk We re on web www.wavedata.co.uk