Venturi versus peristaltic pumps 33 vitrectomy dynamics 34 Fluorescein, vitreous staining 120

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Subject Index Accurus 35, 83 Aflibercept, diabetic macular edema management 167, 168 Air-forced infusion, Stellaris PC 12, 13 Alcon Constellation, see Constellation system Autoclave sterilization lens 89 Bausch & Lomb Stellaris PC, see Stellaris PC Bevacizumab diabetic macular edema management 167 pharmaco adjuvant therapy 129 132 retinopathy of prematurity management 230 submacular hemorrhage surgery adjuvant 216 220 Binocular Indirect Ophthalmo Microscope 88, 115 Brilliant blue G, internal limiting membrane staining 122, 123 Cataract, see Intraocular lens, Nucleus drop/retained lens material Chandelier, endoillumination 84, 88, 160 Chromo advantages in microincision surgery 123, 124 internal limiting membrane staining with vital dyes 122, 123 overview 120, 121 triamcinolone acetate staining of vitreous 121, 122 Closure, 74, 75 Colchicine, proliferative vitreoretinopathy Conjunctival sac, disinfection 68 Constellation system aspiration systems 35 duty cycle control 4 6 high-speed cutting 1 3, 35 illumination 80 82 integrated laser and gas mixing 6 intraocular pressure control 6, 32 small-gauge vitrector probes 3, 4 27-gauge 60 UltraVit 35 Dexamethasone, diabetic macular edema management 167 Diabetic macular edema classification 164, 165 medical therapies 165, 167, 168 optical coherence tomography 165, 166, 170 pathogenesis 164 role in management 168 technique 168, 169 timing 169, 170 Diabetic retinopathy, see Proliferative diabetic retinopathy Disinfection, agents 65 67 conjunctival sac 68 eyelid skin 67, 68 surgical field 68 70 Duty cycle, equation 5 Endoillumination brightness 83 chandelier 84, 88 Constellation system 80 82 Enhancing Visual Acuity system 26 overview 77, 78 prospects 85 requirements 83, 84 safety 78 82 243

Stellaris PC 14, 15 tissue visualization 84, 85 Endophthalmitis, microincision surgery complication 75 Endoscopic cyclophotocoagulation 115 Enhancing Visual Acuity System accessories 28 combined procedures 27, 28 comparison with other systems 30 development 23, 24 duty cycle control 26 ergonomics 28 fluidics 24 26 foot pedal 28 high-speed cutting 26 illumination 27 infusion control 27 laser 27 outcomes 28 prospects 29, 30 service and support 30 small-gauge instrumentation 26 training 29 23-gauge 43 Entry site alignment, Stellaris PC 10 12 Epiretinal membrane indications for surgery 160, 162 internal limiting membrane peeling 160 overview 159 postoperative management 160, 161 prognostic factors after surgery 161, 162 removal 160 small incision techniques and advantages 35, 36 25-gauge 48 systems 160 Etoposide, proliferative vitreoretinopathy Eyelid skin, disinfection 67, 68 Flow rate, equation 3 Fluidics aspiration fluidics and vitreous cutting 32, 33 efficiency concerns 34 Enhancing Visual Acuity system 24, 25, 28 infusion system 31, 32 phaco technique versus 34 Stellaris PC 12 23-gauge 42, 43 Venturi versus peristaltic pumps 33 dynamics 34 Fluorescein, vitreous staining 120 Giant retinal break microincision surgery technique 183 186 suprachoroidal buckling management 142, 144 treatment overview 182, 183 25-gauge management 50 Hagen-Poiseuille law 3, 56 Hypotony, microincision surgery complication 75 Illumination, see Endoillumination Incisions closure 74, 75 oblique or angled incision 73, 74 stab or straight incision 72, 73 Indocyanine green, internal limiting membrane staining 120, 122 InnoVit 35 Internal limiting membrane inverted peeling technique 154 peeling 48, 49, 138, 139, 145, 151, 153, 160, 206 208, 210 staining 120, 122, 123 Intraocular gas, see Tamponade substances Intraocular lens dislocation 239 241 nucleus drop/retained lens material considerations 236, 237 phaco 105 Intraocular pressure control 6, 32 intraocular gas effects 96 perfluorocarbon liquid effects 93, 94 Length of traction, equation 1 Macular buckling, macular hole retinal detachment management 210 Macular edema, see Diabetic macular edema Macular hole classification 150, 151 complications of surgery 157 ocriplasmin studies 156, 157 244 Subject Index

photocoagulation 210 postoperative imaging 155 preoperative evaluation 151, 152 suprachoroidal buckling management 138 141 surgical technique core 152 fluid-air exchange 153, 154 internal limiting membrane peeling 153, 154 posterior hyaloid separation 152 wound construction 152 27-gauge 155, 156 Macular hole retinal detachment, management 208 210 Microincision surgery, see also specific indications and systems complications 75 criticisms 55, 71 globe fixation and site preparation 72 historical perspective 54, 55 incisions, see Incisions instrumentation 72 tamponade, see Tamponade substances Minocycline, proliferative vitreoretinopathy Myopic traction maculopathy macular hole retinal detachment 208 210 myopic foveoschisis 204, 205 overview 204 suprachoroidal buckling management 138, 139, 145 complications 209, 210 outcomes 207 tamponade 210 technique 205 207 Myringovitreoretinal blade 39 N-acetylcysteine, proliferative vitreoretinopathy Nucleus drop/retained lens material anterior segment management 235, 236 complications 232 incidence in cataract surgery 234 intraocular lens dislocation 239 241 placement decision 236, 237 pars plana 237, 238 risk factors 232 Ocriplasmin macular hole studies 156, 157 vitreomacular adhesion syndrome treatment 127 Office-based, limitations 18, 19 Optical coherence tomography diabetic macular edema 165, 166, 170 intraocular imaging 147 149 macular hole 150 152 macular hole retinal detachment 209 myopic foveoschisis 204, 205, 207, 209 postoperative imaging 155 Optical fiber-free intravitreal surgery system 88, 89 Perfluorocarbon liquids, see Tamponade substances Phaco complications 106 overview 102, 103 technique capsulorhexis 104 corneal incision 104 dilation 103 intraocular lens 105 phacoemulsification 104, 105 sclerostomy 103, 104 trocars 103 106 Pharmaco adjuvant agents antiangiogenic agents 129 triamcinolone acetate 132 prospects 132, 133 vitreolysis 126 129 Photon 1 light source 82, 84 Photon 2 light source 85 Povidone-iodine disinfection 65 69 solution preparation 70 Prinomastat, proliferative vitreoretinopathy Proliferative diabetic retinopathy, complications 200 difficult cases 200, 202 overview 196, 197 25-gauge 51 Proliferative vitreoretinopathy classification 190 Subject Index 245

etiology 188 natural history 189, 190 pathophysiology 188, 189 pharmacological treatment 193, 194 risk factors 189 surgical management goals 190, 191 instrumentation 191, 192 membrane removal 192 peripheral cleaning 192 posterior hyaloid membrane traction release 192 tamponade 192, 193 25-gauge management 50, 51 Pump, Venturi versus peristaltic pumps 33 Ranibizumab, diabetic macular edema management 167 RESIGHT system 88, 89, 91 Retinal detachment, see also Macular hole retinal detachment, Tractional retinal detachment postoperative care 180 proliferative vitreoretinopathy after surgery, see Proliferative vitreoretinopathy anesthesia and prepping 175, 176 gas injection 180 heavy liquid removal 179 instrumentation 175 overview 174 pearls 180 posterior vitreous detachment induction 177 retina flattening 178, 179 retinopexy 179 sclerotomy closure 180 technique 176 25-gauge 49, 50 vitreous shaving 177, 178 Retinopathy of prematurity pathophysiology 223, 224 surgical management aggressive posterior disease and early surgery 225, 227, 228 anti-vegf therapy 230 dye staining 231 enzymatic vitreolysis 230 gauge selection for 225 lens-sparing 224, 225 outcomes 224, 226, 227, 229 principles 224 scleral buckling 224 sclerotomy 225 steroid therapy 230, 231 tamponade 228, 230 techniques 225 viewing systems 225 Setup, 63 66 Silicone oil, see Tamponade substances Stellaris PC controls and foot pedal 9, 10 fluidics 12 high-speed cutter 12 14 illumination 14, 15 lasers 15 overview 8, 9, 16 trocar/cannula system 10 12 Submacular hemorrhage natural history 213, 214 surgery anti-vegf adjuvant therapy 217 220 gas tamponade 216, 217 pneumatic displacement subretinal pneumatic displacement 216 tissue plasminogen activator combination 215, 216 prospects 220 technique 215 tissue plasminogen activator use 214 216 Suprachoroidal buckling devices and materials 136 138 macular hole management 138 141 myopic traction maculopathy management 138, 139, 145 overview 136 peripheral break management 140, 142 144 suprachoroidal space 136 Suramin, proliferative vitreoretinopathy Synergetics VersaVIT, see VersaVIT Tacrolimus, proliferative vitreoretinopathy Tamponade substances ideal properties 92, 93 intraocular gases complications 96 246 Subject Index

contraindications 95 postoperative management 95 submacular hemorrhage 216, 217 technique 94, 95 myopic traction maculopathy surgery 210 perfluorocarbon liquid applications 93, 94, 183 186 retinopathy of prematurity surgery 228, 230 silicone oil complications 100 giant retinal tear surgery 183, 184, 186 indications 99, 100 injection and removal 97 99 proliferative vitreoretinopathy surgery 192, 193 properties 96, 97 Taxol, proliferative vitreoretinopathy Tissue plasminogen activator, submacular hemorrhage surgery use 214 216 Tractional retinal detachment bevacizumab induction 129 132 combined tractional and rhegmatogenous retinal detachment 199, 200 complications 199, 200 indications 197 overview 196 198 technique 199 Tranlisat, proliferative vitreoretinopathy Triamcinolone acetate pharmaco adjuvant 132 staining of vitreous 121, 122, 206 23-gauge advantages efficiency 40 hospitalization time 41 postoperative comfort 40, 41 risks 40 speed 40 sutureless surgery 39, 40 antibiotics 43 applications 39 development 38, 39 endoscopic image leveling 116 image optimization 117, 118 indications and outcomes 111 115 instrumentation 109 learning curve 118 optical properties of endoscopy anterior segment opacity 109, 110 reflected versus transmitted light 110, 111 overview 108 pediatric surgery 116 setup 116 fluid-air exchange 43 high-speed cutting 43 instrumentation light probe 43 vitrectome 43 limitations complications 42 costs 41, 42 flow control 42 training 42 utility 42 prospects 44 wound architecture 42, 43 25-gauge cannula removal 46 challenging cases 51, 52 complications 52 diabetic retinopathy management 51 epiretinal membrane removal 48 giant retinal break 50 high-speed cutting 47 indications 45, 46 instrumentation 46 internal limiting membrane peeling 48, 49 proliferative vitreoretinopathy management 50, 51 retinal detachment 49, 50 sclerotomy construction 46 technique 47, 48 27-gauge development 55 efficiency 56, 57 fragility studies 57, 58 indications 58 61 macular hole 155, 156 prospects 61, 62 UltraVit 35 Subject Index 247

Vacuflow Valve Timing Intelligence 23, 24 VersaVIT disadvantages 21 machine pairing 19, 20 office-based limitations 18, 19 surgical aspects 20, 21 Vit 100, proliferative vitreoretinopathy Wide-angle viewing system historical perspective 88, 89 overview 87, 88 types contact lens 89, 90 noncontact lens 90, 91 248 Subject Index