ASICO CATALOG SINGLE USE SURGICAL INSTRUMENTS. SINGLE USE CANNULAS for EFFICIENT Hydrodissection VERSION 1.13

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ASICO SINGLE USE SURGICAL INSTRUMENTS CATALOG VERSION 1.13 SINGLE USE CANNULAS for EFFICIENT Hydrodissection ASICO LLC 26 Plaza Drive Westmont,IL 60559 USA Phone: +1 630-986-8032 Fax: 630-986-0065 Customer Service: 1-800-628-2879 www.asico.com E-mail: info@asico.com 2013 ASICO LLC

SHARP PENETRATION SQUARE WOUND CONSTRUCTION Chemically etched rather than ground to stay sharp Advancut TM Sharpness 27% sharper than BD 45% sharper than Alcon 2 S Clear Corneal Sharpness Squared Sharpness is only half the picture, Consistency is also superior! 2 www.asico.com * Testing at ASICO laboratory

SHARP PENETRATION SQUARE WOUND CONSTRUCTION Why Square? Superior sealing Faster healing The unique geometry bevels on the edge of the blade help to create the perfect square incision for self sealing construction and to prevent wound leakage Photo courtesy of David M. Lubeck, MD Homewood, IL The sharpness of this blade and the square incision make me feel like I am using a diamond knife. James Katz, MD Des Plaines, IL The uniquely designed edge of this keratome is exquisitely sharp and produces exact and square incisions. David M. Lubeck, MD Homewood, IL 2 S These blades are incredibly sharp, provide just the right amount of tissue feel, and create a beautiful long tunnel with remarkable consistency. Douglas Koch, MD Houston, TX Clear Corneal Sharpness Squared Innovation for Better Outcomes 3

SINGLE USE OPHTHALMIC SURGICAL BLADE SHARP & SQUARE Clear Corneal Blade - Double Bevel 2.5mm 2.65mm 2.8mm 3.0mm 2.2mm ASICO Safety Blade CC 2.2mm CC 2.5mm CC 2.65mm CC 2.8mm CC 3.0mm AS-8313ASB AS-8316ASB AS-8318ASB AS-8321ASB AS-8324ASB Clear Corneal Blade - Double Bevel 2.4mm 2.5mm 2.65mm 2.75mm 2.8mm 3.0mm 2.2mm CC 2.2mm CC 2.4mm CC 2.5mm CC 2.65mm CC 2.75mm CC 2.8mm CC 3.0mm Advancut TM AS-8313 AS-8315 AS-8316 AS-8318 AS-8320 AS-8321 AS-8324 Stab 15 4 Stab 15 AS-8210 15 1.7mm -----------------100 µm -------------1 µm S 2 Clear Corneal Sharpness Squared

SINGLE USE CANNULAS PATHOGEN FREE OUTCOMES RETAINED TRYPAN BLUE IN CANNULA FROM CASE 3 DAYS BEFORE! http://webeye.ophth.uiowa.edu/eyeforum/cases-i/case85/ tass-vid.htm TASS Incidents TASS Report Around the World Uncontrollable 1.87% TASS 1.87% of patients develop TASS following anterior segment surgery. The global incidence rate of TASS for these surgeries was 15/801 (1.87%)*. * Korean J Ophthalmology 120,000 CASES About 12 million procedures, even at 1% incidence, could mean 120,000 patients per year, affected by TASS which is a potentially sight threatening disease (EyeNet). And, as indicated, not all cases are captured or reported. Non-Cleaning Instruments The conclusion can be that there are many causes for this problem, but the biggest uncontrollable variable, so far, has been the inability to properly clean reusable instruments. The specific incidence is underreported, however, it is fair based on the above specific information, to ascribe a rate of about 1%. Future studies are necessary to determine the true incidence so that recognition and treatment is given the attention it deserves. Innovation for Better Outcomes 5

EXPERIENCE THE MOST INNOVATIVE TECHNOLOGY DISPOSABLE CANNULAS Hydrodissection Cannulas AS-7627: Disposable Kellan Hydrodissection 25G Cannula, curved Vertical flow, flattened tip for efficient hydrodissection. AS-7629: Disposable Kellan Hydrodissection 25G Cannula, angled Horizontal flow, flattened tip for efficient hydrodissection. AS-7636: Disposable Akahoshi Hydrodissection 27G Cannula Beveled tip can be easily inserted beneath the capsulorrhexis edge. Tapered design easily assists sealing the wound. Most popular design in the product line. AS-7638: Disposable Chang Hydrodissection 27G Cannula Single port at 90 degrees, 1mm tip. The right angle facilitates placement beneath the sub-incisional capsulorrhexis edge to preferentially loosen the sub-incisional cortex. Air injection Cannulas AS-7000: Disposable Rycroft air injection 30G Cannula, 30 gauge 7/8 (22mm) AS-7001: Disposable Rycroft air injection 27G Cannula, 27 gauge 7/8 (22mm) AS-7539: Disposable Terry capsule polisher 27G 27 gauge, Angle to tip: 7.0mm and with silicone sleeve for polishing posterior capsule. Retrobulbar Cannulas AS-7070: Disposable Atkinson Retrobulbar Needle 23G Cannula, 23 gauge 1 1/2 (38.0mm) AS-7071: Disposable Atkinson Retrobulbar Needle 25G Cannula, 25 gauge 1 1/2 (38.0mm) 19 gauge, Angle to tip: 7.0mm 6 www.asico.com SINGLE USE CANNULAS

EXPERIENCE THE MOST INNOVATIVE TECHNOLOGY DISPOSABLE CANNULAS Irrigating Cannula AS-7200: Disposable Bishop-Harmon Irrigating 19G Cannula Cortex Removal Cannulas AS-7208: Disposable J-Shaped 27G Cannula, 27 gauge and tip width: 1.5mm AS-7209: Disposable J-Shaped 25G Cannula, 25 gauge and tip width: 1.75mm AS-7430: Disposable Simcoe Cortex Extractor 23G Cannula, curved 23 gauge, Curved with 0.3mm port, Ideal for removing 12 o clock cortex from side port. Innovation and Quality in Ophthalmic Products and Service Since 1983. ASICO precision ophthalmic surgical instruments are used and trusted by leading surgeons throughout the world. We constantly research the requirements of today s surgeon, to better provide dependable products for the very latest procedures. If we can be of special assistance of you, please contact us. Quality Control We follow the strictest of standards to ensure precision performance and consistency in each instrument. Reseach and Development/Instrument Design Continuous testing of new materials, finishes and concepts leads us to the development of new instruments for new procedures or to improve existing procedures. We welcome your thoughts on the development of new instruments. Our Guarantee All ASICO ophthalmic instruments are unconditionally guaranteed against manufacturing defects in material and workmanship when used for their intended surgical purpose and cared for in accordance with recommended procedure. In the event any ASICO instrument does not meet your requirement as a result of a manufacturing defect in material or workmanship, it will be replaced at no charge. Gauge Conversion Chart Gauge ID (in.) ID (mm) OD (in.) OD (mm) 19g.028.70.043 1.10 20g.024.60.036.90 21g.020.51.032.80 22g.016.41.028.70 23g.013.33.025.60 24g.012.30.022.55 25g.010.25.018.45 26g.010.25.018.45 27g.008.20.016.40 30g.006.15.012.30 Scan to Watch Advancut TM Blade Video SINGLE USE CANNULAS Innovation for Better Outcomes 7

ASICO s Ophthalmic Instruments Available at your local distributor ASICO LLC 26 Plaza Drive Westmont, IL USA 60559 Ph. +1 630-986-8032 Fax. +1 630-986-0065 email: info@asico.com www.asico.com BR539-13