Biomechanical Effects of Femoral Component Axial Rotation in Total Knee Arthroplasty (TKA)

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Biomechanical Effects of Femoral Component Axial Rotation in Total Knee Arthroplasty (TKA) Mohammad Kia, PhD, Timothy Wright, PhD, Michael Cross, MD, David Mayman, MD, Andrew Pearle, MD, Peter Sculco, MD, Geoffrey Westrich, MD, Carl Imhauser, PhD

Disclosures Timothy Wright, PhD receives royalties from and owns stock in Exactech, Inc. Michael Cross, MD is a paid consultant for Exactech, Inc. Geoffrey Westrich, MD is a paid consultant and speaker for Exactech, Inc.

Total Knee Replacement (TKR) Osteoarthritis TKR After Femoral component Tibial insert

Patient Dissatisfaction Following TKR http://www.gregorymartinmd.com

Femoral Component Alignment Femoral cuts Femoral component

Femoral Component Rotation Tibiofemoral kinematics Patellofemoral kinematics Articular contact force Collateral ligament tension

Excessive Internal Rotation of the Femoral Component Qualitatively increases medial collateral ligament (MCL) tension Knee pain and stiffness Anouchi YS, et al. Clin Orthop Relat Res. Feb 1993

External Rotation medial sulcus lateral epicondyle TEA 3-4 PCA

Variability from Patient to Patient

Research Questions How does external rotation alter collateral ligament tensions and tibiofemoral contact forces across a subpopulation of knees? What anatomic factors of the femoral condyle explain variations in maximum MCL tension among knees?

Computational Model Kia et al. J Biomech Eng 2016

Role of Modeling in Ideation Apply Forces Control Ligament Properties Predict Loads -Contact -Ligament Sensitivity Femoral Component Rotation Ideation Implant Placement

Model Development recipe

Bony Geometries Three neutrally aligned, nonarthritic, male cadaveric legs Ages: 20,21, 42 Obtained from CT scans 0.6 mm slice thickness, 0.6x0.6 mm 2 in-plane pixel dimensions

Implant Design Optetrak Logic TM Posterior Stabilized (PS) Knee Exactech Inc. 8mm 9mm 8mm

Implant Placement via Measured Resection Proximal tibial cut Perpendicular to mechanical axis Max 9 mm bone resection Distal femoral cut Perpendicular to mechanical axis Max 8 mm bone resection

Posterior Femoral Cut Long axis 3 PCA

Model of Soft Tissue Envelope

Medial Collateral Ligament (MCL) Proximal Transverse Distal

Force Ligament Properties Slack length Toe region Linear region Elongation Kia et al. J Biomech Eng 2016

Contact Force F c = Ax b

Method to Address Question One Input Flexion Arc 0-90 500N Femoral component external rotation 0 3 6 9 Output Force Collateral ligaments Contact

Representative Simulations 0 9 MCL LCL

MCL tension (N) Medial Collateral Ligament Knee 1 Knee 2 Knee 3 Flexion ( ) Flexion ( ) Flexion ( )

LCL tension (N) Lateral Collateral Ligament Knee 1 Knee 2 Knee 3 Flexion ( ) Flexion ( ) Flexion ( )

Medial Contact (N) Medial Compartment Contact Knee 1 Knee 2 Knee 3 Flexion ( ) Flexion ( ) Flexion ( )

Lateral Contact (N) Lateral Compartmental Contact Knee 1 Knee 2 Knee 3 Flexion ( ) Flexion ( ) Flexion ( )

Method to Address Question Two Posterior cut r p Medial sulcus TEA ratio = r p r d r d Distal cut

Max MCL Tension vs. TEA ratio

Method to Address Question Two Posterior cut r p Proximal MCL insertion MCL ratio = r p r d r d Distal cut

Max MCL Tension vs. MCL ratio

Discussion

Clinical Implications MCL tension = Subfailure damage Difference in compartmental contact forces = Patient satisfaction

Patent Pending

Acknowledgements Clark and Kirby Foundations Hospital for Special Surgery Adult Reconstruction and Joint Replacement Service Research Grant

Thank you

Appendix

External ( ) Internal/External Tibial Rotation Knee 1 Knee 2 Knee 3 Flexion ( ) Flexion ( ) Flexion ( )

Varus ( ) Varus/Valgus Rotation Knee 1 Knee 2 Knee 3 Flexion ( ) Flexion ( ) Flexion ( )

Ligament property Toe region Linear region F(l, l, l 0 ) = 1 n f l + c d lb 1 B 2 + K l l 0 + Δ t + f l 0 + Δ t + c d lb 1 B 3 B 1 = step l, 0, 0, l + 0.1, 1 B 2 = step l, l 0, 0, l 0 + 0.1, 1 step l, l 0 + Δ t, 1, l 0 + Δ t + 0.001,0 B 3 = step l, l 0 + Δ t, 0, l 0 + Δ t + 0.001,1

Optimization 9 a min F i,j m l, l, l 0 2 1 2 F i e 4 i=1 j=1 a = number of fibers for each ligament with 9 ligaments included in the optimization F i m = ACL, smcl, LCL, FFL, OPL, POL, MPC, LPC, PCL PM F e i = 37, 4, 20, 1, 10, 18, 1, 4, 10 N a = 6, 6, 1, 1, 2, 3, 3, 3, 4 fibers l 0 = l e 100 x % 10 x +10

Ligament Force F Optimization Ligament force at full extension (F e )- from the experiment F e Ligament length at full extension (l e )- from the model l e l 0 Ligament length l

Ligament Force Optimization F e F Ligament force at full extension (F e ) Ligament length at full extension (l e ) l 0 l e Ligament length l

Ligament Force Optimization F Ligament force at full extension (F e ) F e Ligament length at full extension (l e ) 0. 9 l e l 0 l e 1. 1 l e Ligament length l

Lateral Contact (N) Medial Contact (N) Lateral vs. Medial Contact Force Knee 3 Knee 3 Flexion ( ) Flexion ( )

Method to Address Question Two Medial sulcus Posterior cut Medial sulcus r p stea ratio = r p r d r d Distal cut

Force (N) Contact Force Experiment Power function R 2 = 0.995 Displacement (mm)

Method to Address Question Two r p Proximal MCL insertion r d MCL ratio = r p r d

Medial Collateral Ligament (MCL) MCL Proximal Transverse Distal