Demystifying the Cell Biology of Cancer

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Demystifying the Cell Biology of Cancer Saturday, September 25, 2010 8:00 AM 12:00 noon Presented by: Linda Workman, PhD, RN, FAAN The Christ Hospital; A Level; Classroom 4 2139 Auburn Avenue; Cincinnati, Ohio 45219

Are you interested in broadening your knowledge base of cell biology of cancer, including: Membrane receptors? Signal transduction pathways? Genetic factors influencing malignant transformation? Targeted therapies for cancer therapy?? Then this course is for you!! FACULTY: Linda Workman, PhD, RN, FAAN, graduated from the University of Cincinnati with her BSN and MSN in Nursing, and with her PhD in Developmental Biology. She completed her postdoctoral work in Cancer Genetics at Children s Hospital Medical Center. During the last 30 years, Linda has honed her ability to effectively teach complex biology-based information to many levels of nursing curriculum. Recently, Linda was the PI for an extensive R25 grant from the National Cancer Institute, and was responsible for developing and implementing a five year program for enhancing genetic knowledge among advanced practice nurses for the Oncology Nursing Society. Linda Workman has published extensively in peer reviewed journals and has written numerous book chapters related to genetics and cancer. Linda has received many awards, including being inducted as a Fellow in the American Academy of Nursing (FAAN, 1992) and receiving the Excellence in Teaching Award (Case Western Reserve University, 1995, 2004, 2005; University of Cincinnati, 2001). She has presented locally, nationally and internationally on the topic of genetics and cancer. COURSE OBJECTIVES: 1. Compare the characteristics and responses of normal cells, early embryonic cells, and transformed cells. 2. Analyze the influences of membrane receptors, signal transduction pathways, and transcription factors in the regulation of cell division. 3. Examine genetic factors influencing malignant transformation, including mutational events in suppressor genes and oncogenes. 4. Differentiate the mechanisms of current and proposed targeted therapies use to disrupt cancer cell division.

LOCATION: The course will be held in Classroom 4 on A level at The Christ Hospital. The Christ Hospital is located at: 2139 Auburn Avenue; Cincinnati, Ohio 45219. TARGET AUDIENCE: Physicians, Pharmacists, Nurses, and other Healthcare Professionals who are interested in gaining a clearer and more thorough understanding of the cellular biology of cancer. CONTACT HOURS For additional information about contact hours for physicians or nurses, contact Gigi Robison at email: Jeanene.robison@thechristhospital.com. REGISTRATION: There are 2 options for registering for this course: Option A - Mail: - Complete the Registration Form (which is part of this brochure) - Return the Registration form and check ($25.00) via mail to Gigi Robison at: 4-West; The Christ Hospital; 2139 Auburn Avenue; Cincinnati, Ohio 45219. Option B - email: - Complete the Registration Form (which is part of this brochure) - Return form to Gigi Robison via FAX at (513) 585-1649 or at email address: Jeanene.robison@thechristhospital.com. - Bring a check ($25.00) to the program on Saturday, September 25th. REGISTRATION FEE: Registration fee includes all handouts, breakfast, lunch, and continuing education hours. This fee is: Free to physicians, pharmacists, nurses, and other healthcare providers who practice at The Christ Hospital $25.00 for all other participants Make checks payable to: Oncology Education Fund REGISTRATION DEADLINE: Friday, September 17, 2010

DEMYSTIFYING THE CELL BIOLOGY OF CANCER: Sat, 9/25/10 Presented by: Linda Workman, PhD, RN, FAAN Time Topic 7:30 8:00 AM Registration and Breakfast 8:00 8:05 AM Welcome and Discussion of Significance of Topic Dr. Leming 8:05 8:10 AM Overview 8:10 9:00 AM Cell Biology A. Normal Cell Biology B. Embryonic Cell Biology C. Cancer Cell Biology 9:00 9:05 AM Break 9:05 9:55 AM Cell Division A. External and internal influences B. Signal transduction C. Apoptosis D. Genetic control 9:55 10:05 AM Break 10:05 11:00 AM Genetic Origin of Cancer A. Molecular Genetics 1) Genetic structure and function 2) Protein synthesis 3) Mutational events and their consequences B. Malignant transformation 1) Initiation 2) Promotion 3) Oncogenes 4) Suppressor genes 11:00 11:05 AM Break 11:05 11:55 AM Molecular Targets A. Generic Targets B. Personal Targets 11:55 12:00 noon Evaluation and Awarding of CE credits

REGISTRATION FORM: Demystifying the Cell Biology of Cancer Saturday, September 25, 2010 Name: Address: City: State: Zip Code: Home Phone: Cell Phone: Work Phone: Employer: Email Address: RN License#: RN License State: Check the applicable Registration Fees: $ 25.00 / participant FREE to The Christ Hospital MDs, Pharmacists, RNs, and other Health Care Providers Make check payable to: Oncology Education Fund OPTION 1: Mail Registration Form and Check to: Gigi Robison, RN, Oncology CNS; 4-West; The Christ Hospital 2139 Auburn Avenue; Cincinnati, OH 45219 OPTION 2: Fax Registration Form to 513-585-1649 Bring the check to course on September 25, 2010. REGISTRATION DEADLINE: Fri, September 17, 2010