Advances in Oncology th Annual. October 10-11, 2014 Hyatt Regency Sacramento, CA CONFERENCE DIRECTORS

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15 th Annual Advances in Oncology 2014 October 10-11, 2014 Hyatt Regency Sacramento, CA (The October 10th conference is held at the Cancer Center Auditorium ) CONFERENCE DIRECTORS Helen K. Chew, M.D. Department of Internal Medicine Primo Lara, Jr., M.D. Department of Internal Medicine PRESENTED BY COMPREHENSIVE CANCER CENTER SPONSORED BY: THE MEDICAL EDUCATOR CONSORTIUM

COURSE DESCRIPTION The 15th Annual Advances in Oncology program will bring together academic and community oncologists for the purpose of educating participants on the state-ofthe-art clinical management of a wide variety of solid and hematologic malignancies. The program is designed to update physicians and other cancer healthcare providers on recent advances and new diagnostic and treatment modalities in hematologic, breast, lung, gastrointestinal, and genitourinary cancers. This course is intended for physicians and cancer health care providers, including medical, surgical and radiation oncologists, nurses, physician assistants, pharmacists and other interested health care professionals. The conference includes didactic sessions from national oncology leaders and case-based panel discussions involving academic and community oncologists. EDUCATIONAL OBJECTIVES At the conclusion of this symposium, you should be able to: 1. Discuss advances in prognostic and predictive biomarkers and potential applications in therapeutic decision making. 2. Integrate targeted and traditional therapeutic modalities in the treatment of cancer. 3. Assess newly validated treatment options for patients with solid tumors or hematologic malignancies 4. Apply data from recent clinical trials to determine the optimal course of therapy in defined patient populations, with emphasis on novel agents including mtor inhibitors, ALK inhibitors, monoclonal antibodies, multi-targeted tyrosine kinase inhibitors, and bone-targeting agents, among others. NEEDS ASSESSMENT The diagnosis, risk stratification, and multi-modality state-of-the-art treatment of hematologic and solid malignancies are rapidly evolving. The development of molecular prognostic assays and novel targeted therapies provides promising tools for personalized medicine. As a result of prior course participant evaluations and needs assessment surveys, the need for cutting edge information on prognostic markers and appropriate application of novel therapies has been identified. This year s conference will specifically address these needs in the common malignancies identified by past participants as essential to their practice, including solid and hematologic cancers. The timing of this meeting in the fall allows for the latest findings in clinical cancer research from major hematology and oncology conferences to be presented and discussed. This educational activity also meets a unique need for the Northern California Sacramento Valley to provide a group of networked and collaborating oncologists a forum to discuss the most recent developments in oncology care in the context of local treatment approaches, patient populations, and open clinical trials. The course is designed to change physician competence in oncology care. State of the art lectures and panel discussions from local and national oncologists will provide ample discussions on the applications and challenges of new prognostic tools and targeted and cytotoxic therapies. Pre-lecture and post-lecture audience response systems (evaluations) will be used in outcome measures. ACCREDITATION The Medical Educator Consortium is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians. CREDIT HOURS The Medical Educator Consortium designates this live activity for a maximum of 7.0 AMA PRA Category 1 Credit(s). Physicians should only claim credit commensurate with the extent of their participation in the activity. DISCLOSURE The Medical Educator Consortium (MEC) adheres to the ACCME Standards for Commercial Support. All persons that will be in a position to control the content of the CME Activity are required to disclose all relevant financial relationships. Faculty disclosure forms outlining this information will be made available to all participants prior to educational activity. MEC has also implemented a mechanism to identify and resolve all conflicts of interest prior to the education activity being delivered to learners. The source of all support from commercial interests will also be disclosed to learners prior to the beginning of the educational activity. NURSING CONTINUING MEDICAL EDUCATION Continuing Medical Education is acceptable for meeting RN continuing education requirements, as long as the course is AMA PRA Category 1 Credits, and has been taken within the appropriate time frames.

FACULTY AND PANELISTS Mehrdad Abedi, M.D. Associate Kristie Bobolis, M.D. Medical Oncologist Capitol Hematology-Oncology Richard Bold, M.D. and Division Chief Division of Surgical Oncology Helen K. Chew, M.D. David Cooke, M.D. Assoc. Program Director, Cardiothoracic Surgery Residency Division of Cardiothoracic Surgery UC Davis Medical Center Marc Dall Era, M.D. Department of Urology UC Davis Medical Center Megan Daly, M.D. Department of Radiation Oncology Lawrence H. Einhorn, M.D. Distinguished Lance Armstrong Professor Medicine Indiana University School of Medicine Indianapolis, Indiana Tim Grennan, M.D. Hematologist-Oncologist Kaiser Permanente Medical Group, Morse Richard Guy, M.D. Hematologist-Oncologist Kaiser Permanente Medical Group, Roseville Kendra Hutchinson, M.D. Associate Professor Brian Jonas, M.D. UC Davis Medical School Karen Kelly, M.D. Associate Director for Clinical Research Primo Lara, Jr., M.D. Associate Director for Translational Research Luko Laptalo, M.D. Sacramento Center for Hematology/Medical Oncology Radiological Associates of Sacramento Tianhong Li, M.D., Ph.D. Gilbert L. Mandell, M.D. Chief, Hematologist-Oncologist Chief, Pharmacy and Therapeutics The Permanente Medical Group South Sacramento Kim A. Margolin, M.D. University of Washington School of Medicine Fred Hutchinson Cancer Research Center Seattle Cancer Care Alliance Seattle, Washington Aminder Medhi, M.D. Hematologist-Oncologist Stockton Hematology-Oncology Brady Miller, M.D. Associate Physician Diplomate Fremont Rideout Cancer Center in Marysville Division of Hematology Oncology Chong-xian Pan, M.D., Ph.D. Associate Professor Jonathan Riess, M.D. Thomas Semrad, M.D. Samer Shihabi, M.D. Sacramento Center for Hematology/Medical Oncology Radiological Associates of Sacramento Joseph Tuscano, M.D. Ted Wun, M.D. Chief, Associate Dean for Research UC Davis Medical Center

AGENDA FRIDAY, OCTOBER 10 TH 11:00 AM Registration and Lunch 11:45 AM Welcome and Introduction (Lois O Grady Lectureship) Ted Wun, M.D. 11:50 AM Opening Lecture: Translational Medicine in Oncology Chong-Xian Pan, M.D., Ph.D. 12:00 PM Introduction of 2014 Lois O Grady Lecture Chong-Xian Pan, M.D., Ph.D. 12:05 PM O Grady Keynote Lecture - Curing Germ Cell Cancer: Lessons Learned and Impact on Solid Tumor Drug Development Lawrence H. Einhorn, M.D. 12:55 PM Question and Answer Session 1:00 PM Faculty Panel Lawrence H. Einhorn, M.D., Chong-Xian Pan, M.D., Ph.D., Ted Wun, M.D. SATURDAY, OCTOBER 11 TH 6:45 AM Registration, coffee, visit exhibits 7:15 AM Breakfast Symposia (non CME) 8:00 AM Welcome Remarks Helen Chew, M.D. and Primo Lara, Jr., M.D. 8:05 AM Pre-Session Survey 8:10 AM Keynote Lecture #1: The Lois O Grady Lectureship Modern Management of Testis Cancer for the Practicing Clinician Lawrence H. Einhorn, M.D. 8:50 AM New Developments in Lung Cancer Therapeutics Jonathan Riess, M.D. 9:10 AM Panel Discussion: Translating Results of Lung Cancer Trials into Clinical Practice Moderator: Megan Daly, M.D. Panelists: David Cooke, M.D., Karen Kelly, M.D., Tina Li, M.D., Samer Shihabi, M.D. 9:40 AM Q&A (Interactive Audience Participation): Lung Cancer 9:45 AM Keynote Lecture #2 State of the Art in Malignant Melanoma Therapy: Bench to Bedside Kim A. Margolin, M.D. 10:15 AM Refreshment Break, visit exhibits 10:30 AM Navigating Breast Cancer Therapeutics: Early and Late Stage Disease 10:50 AM Panel Discussion: Challenging Cases of Breast Cancer Moderator: Helen Chew, M.D. Panelists: Kendra Hutchinson, M.D.,, Kristie Bobolis, M.D. Gilbert Mandell, M.D., Richard Bold, M.D. 11:20 AM Q&A (Interactive Audience Participation): Breast Cancer 11:25 AM Optimal Management of Castration Resistant Prostate Cancer Primo Lara, M.D. 11:45 AM Panel Discussion: Clinical Management of Kidney, Prostate, and Bladder Cancers Moderator: Marc Dall era, M.D. Panelists: Luko Laptalo, M.D., Megan Daly, M.D., Tim Grennan, M.D. Chong-Xian Pan, M.D., Ph.D., Primo Lara, M.D. 12:15 PM Lunch, visit exhibits 1:15 PM New and Emerging Therapeutics in Hematologic Malignancies (Lymphomas/Leukemias) Brian Jonas, M.D. 1:35 PM Panel Discussion: Optimizing Therapy for Patients with Lymphoma or Leukemia Moderator: Joseph Tuscano, M.D. Panelists: Brian Jonas, M.D., Ted Wun, M.D., Richard Guy, M.D. Aminder Mehdi, M.D., Mehrdad Abedi, M.D., Brady Miller, M.D. 2:05 PM Q&A (Interactive Audience Participation): Hematologic Malignancies 2:10 PM Evolving Standards of Care in Gastrointestinal Cancers Tom Semrad, M.D. 2:30 PM Post Session Survey/Closing Remarks

REGISTRATION FORM 15 th Annual Advances in Oncology 2014 Register online at www.meccinc.com or FAX to 305/675-2718. October 10-11, 2014 Hyatt Regency Sacramento, CA Name Degree Address City State Zip Telephone ( ) FAX ( ) Email address Specialty Type of Practice: q Private q Academic q Hospital q Resident/Fellow I will be attending q BOTH days October 10 and 11 q ONLY Friday October 10 at the Auditorium q ONLY Saturday, October 11 at the Hyatt Regency Registration fee $150 Physicians $75 Nurses, Fellows, Residents and Allied Health Care $250 Industry Professionals Refunds must be provided in writing prior to September 10, 2014. After September 10, 2014, No Refunds will be provided. A $50.00 administrative fee is charged on all refunds. Enclosed is my check i/a/o of for registration of this course. I authorize MECC to charge my credit card i/a/o $ for registration of this course using the following credit card. Name on Card Exp. Date Card number Authorized signer CONFERENCE LOCATION This conference is held at two locations. No transportation will be provided from the host hotel. Friday, October 10th Cancer Center Auditorium South Building 4501 X Street, Suite 3016 Sacramento, Ca 95817 Saturday, October 11th HYATT REGENCY 1209 L Street Sacramento, CA 95814 Parking is available in the lot adjacent to the Cancer Center. For more information contact: CONFERENCE MANAGEMENT MEC 1550 S Dixie Highway Suite 202, Coral Gables, FL 33146 Telephone 305/663-1628 Office Fax 305/675-2718 Or visit our website at www.meccinc.com Email: tvalls@meccinc.com

15 th Annual Advances in Oncology 2014 October 10-11, 2014 HYATT REGENCY 1209 L Street Sacramento, CA 95814 MECC, Inc. 1550 South Dixie Highway, Suite 202 Coral Gables, Florida 33146 PRSRT STD U.S. POSTAGE PAID MIAMI, FLORIDA PERMIT NO. 1429