CHAPTER ONE: EXECUTIVE SUMMARY Introduction Scope and Methodology Total Size and Growth of the Market Issues and Trends Affecting Market Leading Competitors CHAPTER TWO: INTRODUCTION AND INDUSTRY TRENDS Overview Introduction to Pathogens Demographics of the World Life Expectancy Infections and Drug Resistance Causes of Drug Resistance Drug Resistance in Select Populations Measures for Reducing Resistance HIV Trends Manufacturer and Marketer Trends Trends in Partnerships and Alliances Developers Trends Aradigm ARD-3100 Phase II Cystic fibrosis ARD-3150 Phase II Bronchiectasis ARD-1100 Preclinical Inhalation anthrax Trends in Rx-to-OTC Switches CHAPTER THREE: ANTIFUNGAL DRUGS Overview Types of Fungal Infections Superficial Systemic General Fungal Infection Statistics Fungal Infection Risk Description of Antifungal Products Systemic Antifungals Topical Antifungals
Market Overview Total Market Size and Forecast Antifungal Market by Product Type Antifungal Market by Geographical Region Market Analysis by Treated Condition Competitive Analysis Leading Products CHAPTER FOUR: ANTIBACTERIAL DRUGS Overview Classification of Antibacterial Organisms Antimicrobial Spectrum Bacterial Resistance Principles of Anti-bacterial Therapy Combination Therapy and Prophylactic Use Bacterial Infection Statistics Bacterial Infection Risk Classifications of Antibacterial Products Aminoglycosides Carbapenems Cephalosporins Macrolides Penicillins Quinolones Sulfonamides Tetracyclines Market Overview Total Market Size and Forecast Antibacterial Market by Product Type Antibacterial Market by Geographical Region Market Analysis by Treated Condition Competitive Analysis Leading Products CHAPTER FIVE: ANTIVIRAL DRUGS Overview: Introduction to Viruses Examples of Pathogenic Viruses Virus Function and Life History Replication in DNA Viruses Replication of RNA Viruses Replication in Retroviruses Host Defenses Against Viruses 8 Viral Ploys to Invade Host Cells and Circumvent Host Responses Invasion of Host Cells
Subversion of the Immune Response Avoidance of Immune Detection and Attack by Killer Cells HIV and AIDS Viral Infection Statistics Description of Antivirals Products Nucleoside Analogs, Transcriptase Inhibitors and DNA Polymerase Inhibitors Protease Inhibitors Other Antivirals Market Overview Total Market Size and Forecast Antiviral Market by Product Type Antiviral Market by Geographical Region Market Analysis by Treated Condition Competitive Analysis Leading Products CHAPTER SIX: MARKET SUMMARY Market by Product Segment (Antifungals, Antibacterials, Antivirals) CHAPTER SEVEN: CORPORATE PROFILES Introduction Abbott Laboratories Astellas AstraZeneca Bayer Healthcare Pharmaceuticals (Bayer Schering Pharma) Bristol-Myers Squibb Cubist Daiichi Sankyo Gilead Sciences GlaxoSmithKline Johnson & Johnson Merck Novartis Pfizer Roche APPENDIX: COMPANY DIRECTORY TABLE OF EXHIBITS CHAPTER ONE: EXECUTIVE SUMMARY Table 1-1: The Global Market for Anti-Infectives by Product Segment, 2007-2015
Figure 1-1: The Global Market for Anti-Infectives by Product Segment, 2011 Figure 1-2: World Market for Anti-Infectives Estimated Market Share of Leading CHAPTER TWO: INTRODUCTION AND INDUSTRY TRENDS Table 2-1: World Population by Selected Geographical Region, 2010-2050 Table 2-2: Average Life Expectancy in Years by Country 1980, 2004 and 2009 Figure 2-2: Average Life Expectancy in Years by Country 1980 and 2009 Table 2-3: Worldwide HIV/AIDS Infections Table 2-4: Women Living with HIV/AIDS, by Region 2001 to 2009, Number Table 2-5: Antiretroviral Access for HIV Infected Individuals in Low- and Middle- Income Countries, 2009 based on 2010 WHO Guidelines Table 2-6: Antiretroviral Access for HIV Infected Individuals in Low- and Middle- Income Countries, by Selected Countries, 2009 based on 2010 WHO Guidelines Table 2-7: Anti-Infective Drugs in Development by Developer Table 2-8: Anti-infectives Ingredients Transferred from Rx-to-OTC Status Figure 2-3: Anti-infectives Ingredients Transferred from Rx-to-OTC by Year CHAPTER THREE: ANTIFUNGAL DRUGS Table 3-1: Incidence of Infections by Type, 2010 Figure 3-1: Incidence of Infections by Type, 2010 Table 3-2: World Population at Risk for Fungal Infections, Secondary to Chronic Diseases by Selected Geographical Region, 2010 Figure 3-2: World Population at Risk for Fungal Infections, Secondary to Chronic Diseases by Selected Geographical Region, 2010 Table 3-3: Treatment Options for Fungal Infections, (Type, Brand, and Manufacturer) Table 3-4: The World Market for Antifungal Drugs 2007-2015 Figure 3-3: The World Market for Antifungal Drugs 2007-2015 Table 3-5: Antifungal Drug Market by Type 2007-2015, (Allylamines, Azoles, Polyene Macrolides, Other Antifungals) Figure 3-4: The World Market for Antifungal Drugs Revenues by Type 2007-2015, (Allylamines, Azoles, Polyene Macrolides, Other Antifungals) Figure 3-5: The World Market for Antifungal Drugs Revenues by Type 2011 and 2015, (Allylamines, Azoles, Polyene Macrolides, Other Antifungals) Table 3-6: The World Market for Antifungal Drugs Estimated Products Sales by Figure 3-6: The World Market for Antifungal Drugs Estimated Product Sales by Table 3-7: World Antifungal Market Estimated Products Sales by Infection Type, (Candida Infections, Seborrheic Dermatitis, Onychomycosis, Other Infections) Figure 3-7: World Antifungal Market Estimated Distribution of Products Sales by Infection Type, 2011 Candida Infections, Seborrheic Dermatitis, Onychomycosis, Other Infections)
Table 3-8: World Market for Antifungal Drugs Estimated Revenues and Market Share of Leading Suppliers 2007-2011 Figure 3-8: World Market for Antifungal Drugs Estimated Revenues of Leading Suppliers, 5-year Comparison 2007-2011 Figure 3-9: World Market for Antifungal Drugs Estimated Market Share of Leading Table 3-9: World Market for Antifungal Drugs Estimated Sales of Select Products 2007-2011 Figure 3-10: World Market for Antifungal Drugs Estimated Sales of Select Products 2007-2011 CHAPTER FOUR: ANTIBACTERIAL DRUGS Table 4-1: Antibiotics with Difficult Penetration Table 4-2: Estimated World and U.S. Incidence of Bacterial Infections, 2010 Figure 4-1: Estimated World and U.S. Incidence of Bacterial Infections Table 4-3: World Population at Risk for Serious Bacterial Infections, Secondary to Chronic Diseases by Selected Geographical Region, 2010 Figure 4-2: World Population at Risk for Serious Bacterial Infections, Secondary to Chronic Diseases by Selected Geographical Region, 2010 Table 4-4: Treatment Options for Bacterial Infections, (Type, Brand, and Manufacturer) Table 4-5: The World Market for Antibacterial Drugs 2007-2015 Figure 4-3: The World Market for Antibacterial Drugs 2007-2015 Table 4-6: Antibacterial Drug Market by Type 2007-2015 Figure 4-4: The World Market for Antibacterial Drugs Revenues by Type, 2007-2015, (Aminoglycosides, Carbapenems, Cephalosporins, Macrolides, Penicillins, Quinolones, Sulfonamides, Tetracyclines, Others) Figure 4-5: The World Market for Antibacterial Drugs Revenues by Type 2011 and 2015, (Aminoglycosides, Carbapenems, Cephalosporins, Macrolides, Penicillins, Quinolones, Sulfonamides, Tetracyclines, Others) Table 4-7: The World Market for Antibacterial Drugs Estimated Products Sales by Figure 4-6: The World Market for Antibacterial Drugs Estimated Product Sales by Table 4-8: World Antibacterial Market Estimated Products Sales by Infection Type, (Upper and Lower Respiratory Tract Infections, Ear, Sinus Infections, Skin & Skin Structure Infections Gynecological Infections; Sexually Transmitted Infections, Urinary Tract Infections, Abdominal Infections, Other Infections) Figure 4-7: World Antibacterial Market Estimated Distribution of Products Sales by Infection Type, 2011, (Upper and Lower Respiratory Tract Infections, Ear, Sinus Infections, Skin & Skin Structure Infections Gynecological Infections; Sexually Transmitted Infections, Urinary Tract Infections, Abdominal Infections, Other Infections) Table 4-9: World Market for Antibacterial Drugs Estimated Revenues and Market Share of Leading Suppliers 2007-2011 Figure 4-8: World Market for Antibacterial Drugs Estimated Revenues of Leading Suppliers 2007-2011
Figure 4-9: World Market for Antibacterial Drugs Estimated Market Share of Leading Table 4-10: World Market for Antibacterial Drugs Estimated Sales of Select Products 2007-2011 CHAPTER FIVE: ANTIVIRAL DRUGS Table 5-1: Host Cell Receptors Table 5-2: Estimated World and U.S. Incidence of Viral Infections, 2010 Figure 5-1: Estimated World and U.S. Incidence of Leading Viral Infections Table 5-3: Treatment Options for Viral Infections, (Type, Brand, and Manufacturer) Table 5-4: The World Market for Antiviral Drugs 2007-2015 Figure 5-2: The World Market for Antiviral Drugs 2007-2015 Table 5-5: Antiviral Drug Market by Type 2007-2015 Figure 5-3: The World Market for Antiviral Drugs Revenues by Type, (Nucleoside Analogs, Transcriptase Inhibitors, DNA Polymerase Inhibitors, Protease Inhibitors, Other Antivirals) 2007-2015 Figure 5-4: The World Market for Antiviral Drugs Revenues by Type, (Nucleoside Analogs, Transcriptase Inhibitors, DNA Polymerase Inhibitors, Protease Inhibitors, Other Antivirals) 2011 and 2015 Table 5-6: The World Market for Antiviral Drugs Estimated Products Sales by Figure 5-5: The World Market for Antiviral Drugs Estimated Product Sales by Table 5-7: World Antiviral Market Estimated Products Sales by Infection Type (HIV, Hepatitis, Other Infections, Total) Figure 5-6: World Antiviral Market Estimated Distribution of Products Sales by Infection Type, 2011 (HIV, Hepatitis, Other Infections, Total) Table 5-8: World Market for Antiviral Drugs Estimated Revenues and Market Share of Leading Suppliers 2006-2009 Figure 5-7: World Market for Antiviral Drugs Estimated Revenues of Leading Suppliers 2007-2011 Figure 5-8: World Market for Antiviral Drugs Estimated Market Share of Leading Table 5-9: World Market for Antiviral Drugs Estimated Sales of Top Products 2007-2011 Figure 5-9: World Market for Antiviral Drugs Estimated Sales of Top Products 2007-2011 CHAPTER SIX: MARKET SUMMARY Table 6-1: The Global Market for Anti-Infectives by Product Segment, 2007-2015 Figure 6-1: The World Market for Anti-Infective Drugs 2007-2015 Figure 6-2: The Global Market for Anti-Infectives by Product Segment, 2011 Figure 6-3: The Global Market for Anti-Infectives by Product Segment, 2015