DEMOGRAPHICS IMPACT FACTOR / SPECIALTY FIELD

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2018 MEDIA KIT EPILEPSY CURRENTS Volume 17 Issue 4 Current Status of Treatments for Children with Electrical Status in SlowWave Sleep (ESES/CSWS)... How Closely Should We Monitor for Nocturnal Seizures?... Resting Connectivity in Non-lesional Temporal Lobe Epilepsy... Prime Time for Language Mapping?... Depression and Epilepsy: We Are No Longer One Direction... Deeper, But How?... Hijacking Plasticity During Sleep... How Have We Come This Far? Epilepsy Classification Through the Ages... 214 217 219 221 223 225 227 229 The Big Picture: Systems Biology Approach to Antiepileptic Drug Discovery... Specificity of Anti-Epileptic Drugs... Angelman Syndrome... Phenotype... Degrading Seizures (or, Playing Tag with Nedd4-2)... Pluripotent Stem Cell Neurons: Can Everyone Be Right?... 232 235 237 239 241 244

DEMOGRAPHICS Epilepsy Currents, published by the American Epilepsy Society, is a comment and review journal for clinicians, researchers and care providers. Each issue contains commentaries that interpret and critique recently published original research articles of particular interest as well as short topical scholarly reviews written by experts. Epilepsy Currents is a bi-monthly current-awareness journal providing reviews, commentaries and abstracts from the world s literature on the research and treatment of epilepsy. Epilepsy Currents surveys and comments on all important research and developments in a format that is easy to read and reference. Each issue is divided into two main sections, Basic Science and Clinical Science. An outstanding Editorial Board reviews the literature and assigns topics and articles to world experts for comment. In addition, the Editors commission authoritative review articles on important subjects. MARKETS SERVED Clinical neurologists, pharmacologists, researchers, nurses, psychologists, neurochemists, EEG technicians. and other professionals interested in epilepsy. Readership includes members of the American Epilepsy Society and International League Against Epilepsy. IMPACT FACTOR / 5.625 CIRCULATION / 4,000 3% 2% SPECIALTY FIELD 4% 6% 7% 10% 44% Adult Neurology / Epileptology 44% Pediatric Neurology / Epileptology 26% Electroencephalography / Clinical Neurophysiology 23% Basic Science Research 14% Clinical Science Research 7% 14% Nursing / Advanced Practice 6% Pharmacology 4% 23% 26% Other 10% Neuroimaging 3% Psychology / Neuropsychology 2%

EPILEPSY CURRENTS PRINT MEDIA ISSUANCE BI-MONTHLY ISSUE RESERVATION MATERIAL DUE Volume 17 Issue 4 Current Status of Treatments for Children with Electrical Status in Slow- Wave Sleep (ESES/CSWS)... 214 How Closely Should We Monitor for Nocturnal Seizures?... 217 Resting Connectivity in Non-lesional Temporal Lobe Epilepsy... 219 Prime Time for Language Mapping?... 221 Depression and Epilepsy: We Are No Longer One Direction... 223 Deeper, But How?... 225 Hijacking Plasticity During Sleep... 227 How Have We Come This Far? Epilepsy Classification Through the Ages... 229 The Big Picture: Systems Biology Approach to Antiepileptic Drug Discovery... 232 Specificity of Anti-Epileptic Drugs... 235 Angelman Syndrome... 237 Phenotype... 239 Degrading Seizures (or, Playing Tag with Nedd4-2)... 241 Pluripotent Stem Cell Neurons: Can Everyone Be Right?... 244 Jan/Feb 12/27/17 1/3/18 Mar/Apr 2/23/18 3/2/18 May/June 4/26/18 5/1/18 July/Aug 6/26/18 7/3/18 Sept/Oct 8/24/18 8/31/18 Nov/Dec 9/27/18 10/2/18 2018 ADVERTISING RATES / PER INSERTION BLACK/WHITE 1 3 6 12 COLOR Full Page $2,255 $2,080 $2,010 $1,875 + $1,000 Half Page $1,750 $1,630 $1,450 $1,380 IN ADDITION Quarter Page $940 $880 $815 $750 TO B/W RATE COVER / PREFERRED POSITIONS* PREMIUM OVER EARNED B/W PAGE RATE Inside Front Cover (C2) 35% Inside Back Cover (C3) 25% Outside Back Cover (C4) 50% Other Preferred Positions 15% * Non-cancellable INSERTS 1 LOOSE INSERT PER ISSUE 2-page Insert 3 B/W earned rate +15% 4-page Insert 5 B/W earned rate +15% DISPLAY AD SIZES / DIMENSIONS ARE WIDTH HEIGHT IN INCHES. Trim Size: 8.25 10.875 Epilepsy Currents trims 0.125 off top, bottom and outside edge. Live area should be a minimum of 0.375 inside trimmed edges. LIVE AREA 7.75 x 10.375 QUARTER PAGE 3.5 4.75 FULL PAGE BLEED 8.5 11.125 FULL PAGE 7 10.125 HALF PAGE HORIZONTAL 7.5 4.75 HALF PAGE VERTICAL 3.5 10.125

EPILEPSY CURRENTS DIGITAL MEDIA EPILEPSYCURRENTS.ORG 7,600 MONTHLY PAGE VIEWS 4,500 MONTHLY SESSIONS 3,700 MONTHLY USERS ONLINE RATES 1 MONTHS 3 MONTHS 6 MONTHS 12 MONTHS Leaderboard* / 728 90 pixels $1,500 $1,400 $1,300 $1,200 Top Banner 1 / 468 60 pixels $900 $800 $700 $500 Top Banner 2 / 468 60 pixels $900 $800 $700 $500 Skyscraper / 160 600 pixels $1,100 $1,000 $900 $800 Tile 1 & 2 / 180 150 pixels $700 $650 $500 $400 *Leaderboard available, space permitting LEADERBOARD TOP BANNER 2 OR TOP BANNER 1 TOP BANNER 2 TILE 1 SKYSCRAPER TILE 2

TECHNICAL SPECIFICATIONS Volume 17 Issue 4 Current Status of Treatments for Children with Electrical Status in Slow- Wave Sleep (ESES/CSWS)... 214 How Closely Should We Monitor for Nocturnal Seizures?... 217 Resting Connectivity in Non-lesional Temporal Lobe Epilepsy... 219 Prime Time for Language Mapping?... 221 Depression and Epilepsy: We Are No Longer One Direction... 223 Deeper, But How?... 225 Hijacking Plasticity During Sleep... 227 How Have We Come This Far? Epilepsy Classification Through the Ages... 229 The Big Picture: Systems Biology Approach to Antiepileptic Drug Discovery... 232 Specificity of Anti-Epileptic Drugs... 235 Angelman Syndrome... 237 Phenotype... 239 Degrading Seizures (or, Playing Tag with Nedd4-2)... 241 Pluripotent Stem Cell Neurons: Can Everyone Be Right?... 244 PRINT ADS RESOLUTION / Image resolution for all graphics should be 300 dpi or higher for color or grayscale images and 1200 dpi for bitmap line art. No RGB or Indexed color mode graphics. FORMAT / High-Resolution PDF files are preferred. PDFs should be created using the Press Optimized settings, and all fonts must be embedded. Please verify journal trim and bleeds. File must be set up for correct journal trim, and bleeds must be set at 0.125 beyond the trim. It is recommended that you submit files 1 week prior to the material due date. ONLINE ADS Acceptable file formats include:.gif, Animated.gif,.jpg, and.png. AGENCY COMMISSION There is a standard 15% commission to recognized agencies. Color and position fees are commissionable. TERMS AND CONDITIONS Epilepsy Currents reserves the right to refuse materials and require publication prepayment. Epilepsy Currents does not accept advertising for credit/debit cards, insurance or travel. The advertiser agrees to assume all liability for content of ads printed and must be fully authorized for use of ad s content, including, but not limited to, names, pictures, testimonials, and any copyrighted or trademarked material. In consideration of the publication of advertisements, the advertiser will indemnify and hold the publisher harmless from any loss or expense arising from an advertisement. All claims for errors in advertisements must be made in writing and received within ten days of publication and will be considered only for the first insertion of the advertisement containing the error. An error that does not materially affect the value or content of an advertisement will not qualify for a credit, nor will any credit be allowed if the customer has seen and approved a proof, or a proof was not supplied.