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DEDICATED TO CURING NEUROENDOCRINE CANCER FOCUS ON HEALTH FREE EDUCATIONAL CONFERENCE Friday, May 5, 2017 8 am 2:30 pm Attend in Person or View Livestream PennMedicine.org/Abramson/NETs OPEN TO THE PUBLIC Law Auditorium // Jordan Medical Education Center // Perelman Center for Advanced Medicine 3400 Civic Center Boulevard // Philadelphia, PA 19104

6 TH ANNUAL FOCUS ON NEUROENDOCRINE TUMORS DATE Friday, May 5, 2017 TIME 8 am 2:30 pm LOCATION Law Auditorium Jordan Medical Education Center Perelman Center for Advanced Medicine 3400 Civic Center Boulevard Philadelphia, PA 19104 FREE Parking! FOLLOW US PennCancer NETResearchFoundation @PennCancer @CURENETS #PhillyNETS WHO SHOULD ATTEND: Newly diagnosed, currently in treatment or long-term survivor of: Gastrointestinal Tract NETs including: Pancreatic NETs (hereditary or sporadic) Zollinger-Ellison syndrome (gastrinomas) Insulinomas Alimentary tract NETs (foregut, midgut or hindgut) Functional (carcinoid syndrome) Non-functional Bronchial, Thymic and Carcinoid in other locations Pheochromocytomas and Paragangliomas including hereditary and sporadic forms Hereditary Syndromes associated with Neuroendocrine Tumors If you are a family member or caregiver REGISTRATION To register or for more information, call 800.789.PENN (7366) or visit PennMedicine.org/Abramson/NETs. Parking will be validated Parking information can be found at PennMedicine.org/Abramson/NETs. $25 suggested donation (non-tax deductible) to support the Focus On Neuroendocrine Tumors Conference.Credit cards accepted with on-line registration. Cash, check, money order or credit card accepted the day of the conference.

AGENDA 8:00 am Check In Continental Breakfast, Visit Exhibits and Experts in Integrative Approaches and Survivorship 8:40 am Welcome and Opening Remarks Debbie Cohen, MD, Conference Co-Chair Joseph R. Carver, MD, Chief of Staff, Abramson Cancer Center Ronald Hollander, Executive Director, Neuroendocrine Tumor Research Foundation 8:45 am News from the Neuroendocrine Tumor Research Foundation Ronald Hollander, Executive Director, Neuroendocrine Tumor Research Foundation 8:55 am Genes and NETS: An Evolving Story An update from the SDHB Pheo-Para Coalition Inc. 9:05 am News from the Abramson Cancer Center Dorothy Mejia-Smith, Major Gift Officer, Abramson Cancer Center MORNING SESSION 9:15 am Management of NETs Overview David C. Metz, MD, Gastroenterology Debbie Cohen, MD, Medicine, Nephrology 9:45 am Research and Clinical Update from the Penn NET Center Promising Studies including Car T and Pheo/Para Bryson Katona, MD, PhD, Gastroenterology 10:05 am Interventional Approaches for NETs Michael C. Soulen, MD, Interventional Radiology 10:25 am Nuclear Imaging and Therapy for NETs. Daniel Alexander Pryma, MD, Radiology 10:45 am Break CONFERENCE CO-CHAIRS: David C. Metz, MD, Professor of Medicine, Gastroenterology, Co-Director, Neuroendocrine Tumor Center Debbie Cohen, MD, Associate Professor of Medicine, Director of Clinical Hypertension Programs, Co-director of Neuroendocrine Tumor Program Ronald Hollander, Executive Director, Neuroendocrine Tumor Research Foundation

11:00 am KEYNOTE ADDRESS: Surgery for Metastatic NETs James R. Howe MD, Surgical Oncology and Endocrine Surgery 11:30 am PANEL DISCUSSION: Multidisciplinary Team Approach for Managing NETs 1:00 pm Lunch MODERATORS David C. Metz, MD and Debbie Cohen, MD PANEL MEMBERS Julia N. Kharlip, MD, Endocrinology Jason Brant, MD, Otorhinolaryngology Joseph R. Carver, MD, Cardiology Keith A. Cengel, MD, PhD, Radiation Oncology Nevena Damjanov, MD, Medical Oncology M. Sean Grady, MD, Chair, Neurosurgery James R. Howe, MD, Endocrine and Oncologic Surgery Arturo Loaiza-Bonilla, MD, FACP, Hematology Oncology Daniel Alexander Pryma, MD, Radiology, Nuclear Medicine Kristen M. Stashek, MD, Pathology & Laboratory Medicine Robert E. Roses, MD, Surgery, Endocrine & Oncologic Anna Raper, MS, CGC, Medical Genetics Michael C. Soulen, MD, Interventional Radiology Ursina R. Teitelbaum MD, Medical Oncology AFTERNOON SESSION 1:45 pm Patient Power It Take Guts Neal Niznan, MSW, LCSW, Social Worker Bonnie Bennett, BSN, RN, Clinical Nurse, Neuroendocrine Tumor Center 2:30 pm Conference Closing

James R. Howe, MD KEYNOTE ADDRESS James R. Howe, MD is Professor of Surgery and Director of Surgical Oncology and Endocrine Surgery at the University of Iowa Hospitals & Clinics in Iowa City, IA. He earned his medical degree at the University of Vermont College of Medicine, trained in General Surgery at Barnes Hospital/Washington University, and did a Surgical Oncology fellowship at Memorial Sloan-Kettering Cancer Center in New York, NY. His clinical interest is in the surgical management of primary small bowel and pancreatic neuroendocrine tumors and management of their hepatic metastases. His research interests include clinical studies of NET patients, and understanding the molecular genetics of neuroendocrine tumors at the basic science level. ABOUT Neuroendocrine Tumor Research Foundation NETRF.org The mission of the Neuroendocrine Tumor Research Foundation is to fund research to discover cures and more effective treatments for carcinoid, pancreatic, and related neuroendocrine cancers. ABOUT Abramson Cancer Center PennMedicine.org/Abramson At the Abramson Cancer Center our mission is to reduce the burden of cancer throughout our region, the nation and the world through the development of an integrated program of laboratory, clinical and population based research. The Abramson Cancer Center has been continuously designated as a Comprehensive Cancer Center by the National Cancer Institute (NCI) since 1973. One of only 45 such Centers in the country the Abramson Cancer Center was rated EXCEPTIONAL by the NCI at our last competitive review the highest possible rating a Center can receive. Comprehensive Cancer Center The Focus on Neuroendocrine Tumors Conference is being held in collaboration with the Penn Medicine Development Office and the NET Research Foundation. Attendees will receive communication from the PENN Medicine Development Office regarding their research and programs. Participation in this conference is optional and patient privacy has been maintained. If you would prefer not to receive development materials, we will make reasonable efforts to honor such a request. Please send a written request with your name, and address to Tricia Bruning, Abramson Cancer Center Development Office, 3535 Market Street, Suite 750, Philadelphia, PA 19104 and to NET Research Foundation, 20 Park Plaza, Ste. 478, Boston MA 02116.