Cardiac and Lung Surgical Robots: Market Shares, Strategies, and Forecasts, Worldwide,

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Cardiac and Lung Surgical Robots: Market Shares, Strategies, and Forecasts, Worldwide, 2015-2021 Table of Contents Cardiac and Lung Surgical Robots: Executive Summary The study is designed to give a comprehensive overview of the Cardiac and Lung Surgical Robots equipment market segment. Research represents a selection from the mountains of data available of the most relevant and cogent market materials, with selections made by the most senior analysts. Commentary on every aspect of the market from independent analysts creates an independent perspective in the evaluation of the market. In this manner the study presents a comprehensive overview of what is going on in this market, assisting managers with designing market strategies likely to succeed. Table of Contents Heart and Lung Surgical Robot Executive Summary 21 Heart and Lung Surgical Robot Market Driving Forces 21 Surgical Robotics Market Driving Forces 22 Cardiac Surgical Robot Key Procedures As Elements Of Strategy 24 Cardiac and Lung Surgical Robots Market Share Analysis 25 Cardiac and Lung Surgical Robot Market Forecasts 27 1. Cardiac Surgical Robot Market Description and Market Dynamics 30 1.1 Cardiac Robotic Surgical Clinical Applications 30 1.1.1 Robotic Cardiothoracic Surgery 33 1.1.2 Mitral Valve Repairs Are Preferred Over Mitral Valve Replacement 33 1.1.3 Mitral Valve Repair 34 1.1.4 Mitral Valve Replacement Possible Complications 36 TOC-1 /blog

1.2 Interventional Cardiologists Treatments and Procedures 39 1.3 Robotic Internal Thoracic Artery Dissection 40 1.3.1 Robotic Thoracoscopy 41 1.3.2 Cardiothoracic Surgery 42 1.4 Surgical Robotic Lobectomy 42 1.5 Robotic Coronary Artery Bypass 43 2. Heart and Lung Surgical Robot Market Shares and Market Forecasts 45 2.1 Heart and Lung Surgical Robot Market Driving Forces 45 2.1.1 Surgical Robotics Market Driving Forces 46 2.1.1 Cardiac Surgical Robot Key Procedures As Elements Of Strategy 49 2.2 Cardiac and Lung Surgical Robots Market Share Analysis 50 2.2.1 Intuitive Surgical da Vinci Surgical System Is Food and Drug Administration (FDA) Approved Cardiac and Lung Robotic System 53 2.2.2 Corindus 54 2.2.3 MedRobotics 55 2.3 Cardiac and Lung Surgical Robot Market Forecasts 56 2.4 Cardiac and Lung Surgical Robot Installed Systems and Procedure Volumes by Country 60 2.5 Key Players In The Global Medical Surgical Robots Market 66 2.6 Robotic Surgery Equipment Prices 66 2.1.2 Intuitive Surgical da Vinci Surgical System Prices 67 2.7 Cardiac and Lung Robotic Surgery Equipment Regional Market Segments 68 2.7.1 Intuitive Surgical Regional Revenue 71 2.7.2 Intuitive Surgical European Demand 72 2.7.3 Intuitive Surgical in Japan 72 2.7.4 U.S. Robotic Surgical Procedures 72 TOC-2 /blog

2.7.5 BRIC (Brazil, Russia, India, China) countries 73 2.7.6 Aging Taiwanese Population 73 2.7.7 Korea Focusing On Creating A Growth Engine In Research & Development 74 2.7.8 Korea 74 2.7.9 Brazil 75 2.7.10 Chinese Imported Surgical Robots 75 2.7.11 Chinese Development of Surgical Robots 76 2.8 Chinese Robotic Cardiac Surgery 77 2.8.1 Chinese Robotic Cardiac Team Recognized As One Of World's Best 77 3. Cardiac Surgical Robots Product Descriptions 80 3.1 Intuitive Surgical Cardiothoracic Surgeries 80 3.1.1 Intuitive Surgical da Vinci Surgical System 82 3.1.2 Intuitive Surgical Da Vinci Minimally Invasive Surgical Product 83 3.1.3 Intuitive Surgical Cardiac Surgery 84 3.1.4 Intuitive Surgical da Vinci Surgical System Components 90 3.1.5 Intuitive Surgical Patient-Side Cart and Electromechanical Surgical Arms 94 3.1.6 Intuitive Surgical 3-D Vision System 94 3.1.7 Intuitive Surgical Firefly Fluorescence Imaging 95 3.1.8 Intuitive Surgical. da Vinci Surgical System EndoWrist Instruments 96 3.1.9 Intuitive Surgical Instruments and Accessories 98 3.1.10 Intuitive Surgical da Vinci Single-Site 99 3.1.11 Intuitive Surgical EndoWrist One Vessel Sealer 99 3.1.12 Intuitive Surgical da Vinci Skills Simulator 104 3.2 Titan Medical 105 TOC-3 /blog

3.3 Johnson & Johnson 109 3.3.1 Johnson & Johnson Ethicon 110 3.4 MedRobotics 112 3.4.1 Medrobotics Flex Retractor 114 3.4.2 Medrobotics Flexible Robot Platform 115 3.4.3 Medrobotics Snakelike Robots for Oropharynx, Hypopharynx and Larynx Surgery 116 3.5 Corindus 119 3.5.1 CorPath Robotic Angioplasty 120 3.5.2 Corindus Command. Control CorPath 200 System 121 3.5.3 Corindus Standard in Precision PCI 123 3.5.4 Robotic Angioplasty / Interventional Cardiology 127 3.6 Changzhou Kangxin Medical Instruments Co., Ltd. 128 3.7 Guangzhou Baitang Medical Instrument Co., Ltd. 128 4. Cardiac Surgical Robots Technology and Research 129 4.1 Intuitive Surgical Da Vinci Computerized Technology For Surgery 129 4.2 Intuitive Surgical da Vinci Xi Surgical System Minimally Invasive Surgery 130 4.2.1 Intuitive Surgical da Vinci Surgical System 131 4.3 Third Party Reimbursement 132 5. Cardiac and Lung Surgical Robots Company Descriptions 135 5.1 Chinese Surgical Robots 135 5.2 Corindus 139 5.2.1 Corindus Benefits of CorPath Robotic-Assisted PCI 142 5.2.2 Corindus Improves Staff Position in the Room 143 5.3 Freehand 144 5.3.1 Freehand 2010 / Prosurgics 145 TOC-4 /blog

5.4 Intuitive Surgical 145 5.4.1 Intuitive Surgical Robotics da Vinci Surgical System 151 5.4.2 Intuitive Surgical Robotics da Vinci Surgical System Xi 152 5.4.3 Intuitive Surgical Business Strategy 154 5.4.4 Intuitive Surgical Systems 157 5.4.5 Intuitive Surgical Patient Value As Equal To Procedure Efficacy / Invasiveness 157 5.4.6 Intuitive Surgical Business Model 158 5.4.7 Intuitive Surgical Revenue 159 5.4.8 Intuitive Surgical Regulatory Activities 161 5.4.9 Intuitive Surgical Economic Environment. 161 5.5 Johnson and Johnson / DePuy Synthes 161 5.5.1 Google Collaborating With Johnson & Johnson To Develop Surgical Robots 162 5.5.2 DePuy 162 5.5.3 Johnson & Johnson 163 5.5.4 Johnson & Johnson / Ethicon 163 5.6 Medrobotics 165 5.6.1 Medrobotics Closes On $10 Million Financing 167 5.6.2 Medrobotics Several Generations Of Snake Robot Platforms 168 5.6.3 Medrobotics Advances Clinical Development of Snake Robot for Surgery 168 5.6.4 Medrobotics Positioning 168 5.6.5 Medrobotics Cardiac Surgery Gold Standard 169 5.6.6 Medrobotics Snake Robot Technologies For Use In A Wide Range Of Surgical And Interventional Applications 170 TOC-5 /blog

5.6.7 Medrobotics Technology & Research Center 173 5.7 Medtronic 173 5.7.1 Medtronic PLC 175 5.7.2 Medtronic O-arm Surgical Imaging System 177 5.8 Meerecompany / Eterne 181 5.9 Titan Medical 182 5.9.2 Titan Medical General Surgery Robot Market Opportunities 188 5.9.3 Titan Medical Robotic Surgery Target Opportunity 189 5.10 TransEnterix Acquires the ALF-X Surgical Robotic System 191 5.10.2 TransEnterix Strategic Positioning 191 5.10.3 TransEnterix 193 5.10.4 TransEnterix / Sofar 193 5.11 Surgical Robot Companies 198 List of Tables and Figures TOC-6 /blog

Table ES-1 26 Innovative Surgical Robot Features 26 Table ES-2 27 Surgical Robotics Market Driving Forces 27 Table ES-3 28 Surgical Robot Market Positioning 28 Table ES-4 30 Cardiac and Lung Surgical Robot Medical Sub-Specialties 30 Figure ES-5 31 Cardiac and Lung Surgical Robots Market Shares, Shipments, Dollars, Worldwide 2014 31 Figure ES-6 34 Cardiac and Lung Surgical Robot Systems Forecasts, Dollars, Worldwide, 2015-2021 34 Table 1-1 35 Cardiac Conditions Requiring Surgery 35 Table 1-2 36 Intuitive Surgical Robotic Cardiac Procedures 36 Table 1-3 38 Robotic Surgery Surgical Specialty Focus 38 Table 1-4 40 Mitral Valve Problem Description 40 Table 1-5 41 Causes Of Mitral Valve Problems 41 Table 1-6 41 Mitral Valve Replacement Possible Complications 41 TOC-7 /blog

Table 1-7 42 Factors That May Increase The Risk Of Complications With Heart Surgery 42 Table 1-8 43 Physician-Patient Mitral Valve Heart Valve Assessment Program Aspects 43 Table 1-9 44 Catheter-Based Valve Disease Procedures 44 Table 1-10 45 Cardiac Surgeon Open Surgical Procedures: 45 Table 2-1 50 Innovative Surgical Robot Features 50 Table 2-2 52 Surgical Robotics Market Driving Forces 52 Table 2-3 53 Surgical Robot Market Positioning 53 Table 2-4 55 Cardiac and Lung Surgical Robot Medical Sub-Specialties 55 Figure 2-5 56 Cardiac and Lung Surgical Robots Market Shares, Shipments, Dollars, Worldwide 2014 56 Table 2-6 57 Cardiac and Lung Surgical Robot Market Shares, Dollars, Worldwide, 2014 57 Figure 2-7 63 Cardiac and Lung Surgical Robot Systems Forecasts, Dollars, Worldwide, 2015-2021 63 Table 2-8 64 Heart and Lung Surgical Robot Market Segment Forecasts, Dollars and Units, Worldwide, 2015-2021 64 Table 2-9 65 TOC-8 /blog

Number Intuitive Surgical Cardio/Thoracic Robotic Procedures, 65 Regional Analysis by Procedure Type, 2014 65 Table 2-10 66 Open and Robotic Surgeries: Cardio Thoracic Procedure Forecasts, Number US and Worldwide, 2015-2021 66 Table 2-11 67 Cardio Thoracic Robotic Surgery Procedures By Country, 2014 67 TOC-9 /blog

Abdominal and Cardio Thoracic Robotic Surgery Procedures By Country Installed Procedures in Thousands % Systems % US 11.2 70.0 73.9 Europe 1.9 11.9 22.3 Direct Sales France 0.3 1.9 2.8 Germany 0.3 1.9 2.4 UK 0.3 1.9 1.7 Belgium 0.2 1.3 1.1 Switzerland 0.1 0.6 0.9 Sweden 0.0 0.0 0.8 Netherlands 0.0 0.0 0.6 Denmark 0.0 0.0 0.5 Norway 0.0 0.0 0.4 Chez Republic 0.0 0.0 0.2 Austria 0.0 0.0 0.2 Finland 0.0 0.0 2.4 Iceland 0.0 0.0 1.7 Other 0.0 0.0 0.1 Europe Sold By Distributors Italy 0.2 1.3 2.7 Turkey 0.2 1.3 1.1 Spain 0.2 1.3 1.0 Russia 0.1 0.6 0.8 Greece 0.0 0.0 0.3 Romania 0.0 0.0 0.2 Other 0.0 0.0 0.4 add 1.9 11.9 6.4 Table 2-11 (Continued) 68 Abdominal / Cardio Thoracic Robotic Surgery Procedures By Country, 2014 68 Table 2-12 69 67 TOC-10 /blog

Cardio Thoracic Robotic Surgery Procedure Forecasts, Lobectomy, Mitrial Valve Repair, Vascular Surgery, Number of Procedures, Worldwide, 2015-2021 69 Figure 2-13 74 Cardiac and Lung Surgical Robot Regional Market Segments, Dollars, 2014 74 Figure 2-14 75 Cardiac and Lung Surgical Robot Regional Market Segments, 2014 75 Figure 2-15 82 China Robotic Cardiac Surgery 82 Figure 3-1 86 Intuitive Surgical Integrated Sub Systems 86 Figure 3-2 87 Intuitive Surgical da Vinci Surgical System 87 Figure 3-3 88 Intuitive Surgical Da Vinci Surgery 88 Table 3-4 89 Intuitive Surgical Da Vinci Surgical System Components 89 Table 3-5 90 Intuitive Surgical Cardiac Conditions Addressed 90 Table 3-6 91 Minimally Invasive Da Vinci Surgery Benefits To Cardiac Patients 91 Figure 3-7 92 Intuitive Surgical da Vinci System State-Of-The-Art Robotic Surgical Platform 92 Table 3-8 92 Intuitive Surgical da Vinci Si Surgical System Core Benefits: 92 Figure 3-9 93 Intuitive Surgical da Vinci SI Surgical System Dual Console Used For Training And Collaboration 93 Figure 3-10 94 TOC-11 /blog

Intuitive Surgical. da Vinci Surgical System Vision System 94 Table 3-11 96 Intuitive Surgical da Vinci Xi Surgical System Surgeon Console Features 96 Figure 3-12 97 Intuitive Surgical. da Vinci Surgical System Surgeon Console 97 Figure 3-13 98 Intuitive Surgical. da Vinci Surgical System Patient-Side Cart 98 Figure 3-14 101 Intuitive Surgical. da Vinci Surgical System EndoWrist Instruments 101 Table 3-15 102 Intuitive Surgical da Vinci Surgical System Features 102 Table 3-16 105 Advantages of Intuitive Surgical Cardio Thoracic Robotic Surgery 105 Table 3-17 107 Surgical Robot Cardiothoracic Conditions Treated 107 Figure 3-18 107 Intuitive Surgical da Vinci Surgical System, Surgeon Operates Seated Comfortably At A Console 107 Figure 3-19 108 Intuitive Surgical da Vinci Surgical System Patient Side Cart 108 Figure 3-20 110 Titan Single Port Orifice Robotic Technology SPORT Surgical System 110 Figure 3-21 111 Titan SPORT Surgical System: 111 Table 3-22 113 Titan MedicalSPORT Surgical System Patient Benefits: 113 Table 3-23 114 TOC-12 /blog

Titan MedicalSPORT Surgical System Surgeon Benefits: 114 Table 3-24 116 Johnson & Johnson Ethicon Minimally Invasive Procedures As They Apply To Specific Conditions 116 Figure 3-25 119 Medrobotics Flex Retractor 119 Figure 3-26 122 Medrobotics Snakelike Robot Tested for Heart Surgery 122 Table 3-27 123 Medrobotics Medical Field Target Markets 123 Figure 3-28 125 Corindus CorPath Robotic Angioplasty 125 Figure 3-29 127 Corindus Command. Control CorPath 200 System 127 Figure 3-30 128 Corindus Precise Robotic Movement And Device Fixation 128 Table 3-31 129 Corindus Robotic-Assisted Control Benefits 129 Figure 3-32 130 Occupational Hazards in Cath Lab 130 Figure 3-33 131 Corindus Robotic Assisted PCI 131 Figure 4-1 136 Intuitive Surgical da Vinci Surgical System 136 Figure 5-1 141 Tianjin Municipality Micro Hand A Chinese Surgical Robots 141 Figure 5-2 143 TOC-13 /blog

China's First Surgical Robot For Minimally Invasive Surgery At Tianjin Municipality 143 Table 5-3 145 Benefits of Corindus CorPath Robotic-Assisted PCI 145 Figure 5-4 146 Corindus CorPath Benefits 146 Table 5-5 147 Corindus Benefits of CorPath Robotic-Assisted PCI 147 Figure 5-6 148 Corindus Step Away From Radiation Source During Robotic PCI 148 Table 5-7 149 Corindus CorPath Robotic-Assisted PCI Mean Radiation Dose (per procedure) By Position (μsv)2 149 Figure 5-8 157 Intuitive Surgical Platform, davinci Xi 157 Table 5-9 160 Intuitive Surgical Strategy To Improve Candidate Surgical Procedures 160 Table 5-10 166 Johnson and Johnson Family of Companies Comprises: 166 Table 5-11 170 Medrobotics Positioning 2015 170 Table 5-12 175 Medrobotics Cardiac Surgery Improvements 175 Table 5-12 176 Medrobotics Snake Robot Technologies For Use In A Wide Range Of Surgical And Interventional Applications 176 Table 5-13 177 Medrobotics Snake Robot Technologies Specialist Areas Served 177 TOC-14 /blog

Table 5-14 180 Medtronic O-arm Surgical Imaging StealthStation Navigation Functions 180 Table 5-15 181 Medtronic O-arm Surgical Imaging System Benefits 181 Table 5-16 183 Medtronic O-arm Surgical Imaging System 183 Table 5-17 184 Medtronic O-arm Surgical Imaging System Benefits 184 Figure 5-18 185 Medtronic Lumbar Imaging 185 Table 5-19 188 Titan Medical Investment Summary 188 Figure 5-20 189 Titan Medical Business Goals and Timetable 189 Figure 5-21 193 Titan Medical Describes Robotic General Surgery Market Potential 193 Figure 5-22 195 Titan Medical Robotic Surgery Target Opportunity 195 Table 5-23 197 TransEnterix Strategic Positioning 197 Figure 5-24 199 TELELAP Robotic Surgical Unit 199 Figure 5-25 201 Telelap ALF-X Robotic Surgery 201 Figure 5-26 202 TELELAP ALF-X Breaking Barriers Supporting Precision 202 TOC-15 /blog

TOC-16 /blog