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Serving Hoosier Healthwise and Healthy Indiana Plan November 5, 2015 Provider update: Quarterly pharmacy formulary change notice Effective December 1, 2015, the preferred formulary changes detailed in the table below will apply to Anthem Blue Cross and Blue Shield (Anthem) members enrolled in Hoosier Healthwise and Healthy Indiana Plan. Additionally, effective December 1, 2015 there will be changes to the nonpreferred and prior authorization requirements of these formulary items as well. These formulary changes were reviewed and approved at the second quarter Pharmacy and Therapeutics (P&T) committee meetings held on June 23, 2015. Therapeutic Class www.anthem.com Anthem Blue Cross and Blue Shield is the trade name of Anthem Insurance Companies, Inc. Independent licensee of the Blue Cross and Blue Shield Association. ANTHEM is a registered trademark of Anthem Insurance Companies, Inc. The Blue Cross and Blue Shield names and symbols are registered marks of the Blue Cross and Blue Shield Association. AINPEC-0563-15 November 2015 Formulary changes effective December 1, 2015 Medication Formulary Status Change ANALGESICS IBUDONE 5-200 MG TABLET ANALGESICS RHINOFLEX 500 MG-50 MG TABLET RHINOFLEX-650 TABLET ANALGESICS CHILDREN'S TYLENOL 160 MG/5 ML ANALGESICS ANALGESICS CHILD'S TYLENOL 80 MG MELTAWAY JR. TYLENOL 160 MG MELTAWAYS TYLENOL 325 MG CAPLET TYLENOL 325 MG TABLET TYLENOL 8 HOUR 650 MG CAPLET TYLENOL ARTHRITIS ER 650 MG TB TYLENOL ES FOR ARTHRITIS PAIN TYLENOL EX-STR 500 MG TYLENOL X-STR 500 MG/15 ML LIQ Potential alternatives (preferred products) HYDROCODONE IBUPROFEN ACETAMINOPHEN IBUPROFEN NAPROXEN LITTLE REMEDIES FEVER 160 MG/5ML CHILD TACTINAL 80 MG TAB CHW ACETAMINOPHEN IBUPROFEN NAPROXEN ANALGESICS MENSTRUAL COMPLETE CAPLET PAMPRIN ANTICOAGULANTS ANTICOAGULANTS SAVAYSA 15 MG TABLET SAVAYSA 30 MG TABLET SAVAYSA 60 MG TABLET ELIQUIS 2.5 MG TABLET ELIQUIS 5 MG TABLET XARELTO 15 MG TABLET XARELTO 20 MG TABLET XARELTO STARTER PACK REMOVE PRIOR AUTHORIZATION (PA) AND QUANTITY LIMIT () REMOVE PA AND

ANTIDIABETIC AGENTS ANTIDIABETIC AGENTS ANTIDIABETIC AGENTS ANTIDIARRHEALS AGENTS PRADAXA 75 MG CAPSULE PRADAXA 150 MG CAPSULE GLYXAMBI 10 MG-5 MG TABLET GLYXAMBI 25 MG-5 MG TABLET JENTADUETO 2.5 MG-500 MG TAB JENTADUETO 2.5 MG-850 MG TAB JENTADUETO 2.5 MG-1000 MG TAB TRADJENTA 5 MG TABLET KOMBIGLYZE XR 5-500 MG TABLET ONGLYZA 2.5 MG TABLET ONGLYZA 5 MG TABLET LOPERAMIDE 2 MG (OTC AND RX) LOPERAMIDE 1 MG/5 ML SOLUTION /LIQUID (OTC) LOPERAMIDE 1 MG/7.5 ML SUSPENSION/LIQUID (OTC) Anthem Blue Cross and Blue Shield Page 2 of 6 STEP THERAPY (ST) PREFERRED ANTIFUNGAL AGENTS VFEND 40 MG/ML SUSPENSION ANTIMIGRAINE AGENTS ANTINEOPLASTICS AGENTS ANTINEOPLASTICS AGENTS DIHYDROERGOTAMINE 1 MG/ML AM DIHYDROERGOTAMINE 1 MG/ML VL GLEOSTINE 10 MG CAPSULE GLEOSTINE 100 MG CAPSULE GLEOSTINE 40 MG CAPSULE SYLATRON 200 MCG KIT SYLATRON 200 MCG 4-PACK SYLATRON 600 MCG KIT SYLATRON 300 MCG KIT SYLATRON 300 MCG 4-PACK FARYDAK 10 MG CAPSULE FARYDAK 15 MG CAPSULE FARYDAK 20 MG CAPSULE IBRANCE 75 MG CAPSULE IBRANCE 100 MG CAPSULE IBRANCE 125 MG CAPSULE LENVIMA 24 MG DAILY DOSE LENVIMA 14 MG DAILY DOSE LENVIMA 10 MG DAILY DOSE LENVIMA 20 MG DAILY DOSE (CURRENT UTILIZERS WILL BE GRANDFATHERED) JANUMET JANUVIA TRADJENTA JENTADUETO JANUMET JANUVIA TRADJENTA JENTADUETO VORICONAZOLE SUSPENSION SUMATRIPTAN NARATRIPTAN ANTINEOPLASTICS AGENTS SUTENT 37.5 MG CAPSULE CARDIOVASCULAR AGENTS CORLANOR 5 MG TABLET CORLANOR 7.5 MG TABLET CARDIOVASCULAR AGENTS NITROGLYCERIN LINGUAL 0.4 MG NITROGLYCERIN PATCH NITROSTAT TABLET SL

CARDIOVASCULAR AGENTS METHYCLOTHIAZIDE 5 MG TABLET HIV ANTIRETROVIRAL AGENTS IMMUNOSUPPRESSANTS INFLAMMATORY BOWEL DISEASE INFLAMMATORY BOWEL DISEASE AGENTS MISCELLANEOUS NEUROLOGICAL THERAPY MISCELLANEOUS PSYCHOTHERAPEUTIC AGENTS NARCOTIC ANALGESIC NARCOTIC ANALGESIC Anthem Blue Cross and Blue Shield Page 3 of 6 CHLORTHALIDONE METOLAZONE SPIRONOLACTONE All HIV MEDICATIONS REMOVE COSENTYX 150 MG/ML SYRINGE COSENTYX 300 MG DOSE-2 SYRINGE COSENTYX 150 MG/ML PEN INJECT COSENTYX 300 MG DOSE-2 PENS ADD ST APRISO ER 0.375 GRAM CAPSULE PREFERRED ASACOL HD DR 800 MG TABLET DELZICOL DR 400 MG CAPSULE PENTASA 500 MG CAPSULE PENTASA 250 MG CAPSULE EXELON 2 MG/ML ORAL SOLUTION (CURRENT UTILIZERS WILL BE GRANDFATHERED) ASACOL BALSALAZIDE APRISO RIVASTIGMINE CAPSULES ERGOLOID MESYLATES 1 MG TAB FENTANYL 25 MCG/HR PATCH FENTANYL 50 MCG/HR PATCH FENTANYL 75 MCG/HR PATCH FENTANYL 100 MCG/HR PATCH FENTANYL 12 MCG/HR PATCH FENTANYL 62.5 MCG/HR PATCH FENTANYL 87.5 MCG/HR PATCH FENTANYL 37.5 MCG/HR PATCH BUTRANS 5 MCG/HR PATCH BUTRANS 10 MCG/HR PATCH BUTRANS 20 MCG/HR PATCH BUTRANS 15 MCG/HR PATCH BUTRANS 7.5 MCG/HR PATCH EXALGO ER 12 MG TABLET EXALGO ER 32 MG TABLET EXALGO ER 16 MG TABLET EXALGO ER 8 MG TABLET NUCYNTA ER 50 MG TABLET NUCYNTA ER 100 MG TABLET NUCYNTA ER 150 MG TABLET NUCYNTA ER 200 MG TABLET NUCYNTA ER 250 MG TABLET OPANA ER 7.5 MG TABLET OPANA ER 15 MG TABLET OPANA ER 5 MG TABLET OPANA ER 10 MG TABLET OPANA ER 20 MG TABLET OPANA ER 30 MG TABLET OPANA ER 40 MG TABLET ZOHYDRO ER 10 MG CAPSULE ST MORPHINE SULFATE ER FENTANYL PATCH METHDONE

Page 4 of 6 ZOHYDRO ER 15 MG CAPSULE ZOHYDRO ER 20 MG CAPSULE ZOHYDRO ER 30 MG CAPSULE ZOHYDRO ER 40 MG CAPSULE ZOHYDRO ER 50 MG CAPSULE HYSINGLA ER 20 MG TABLET HYSINGLA ER 30 MG TABLET HYSINGLA ER 40 MG TABLET HYSINGLA ER 60 MG TABLET HYSINGLA ER 80 MG TABLET HYSINGLA ER 100 MG TABLET HYSINGLA ER 120 MG TABLET NARCOTIC ANALGESIC EMBEDA ER 20-0.8 MG CAPSULE EMBEDA ER 30-1.2 MG CAPSULE EMBEDA ER 50-2 MG CAPSULE EMBEDA ER 60-2.4 MG CAPSULE EMBEDA ER 80-3.2 MG CAPSULE EMBEDA ER 100-4 MG CAPSULE ADD ST MORPHINE SULFATE ER FENTANYL PATCH METHDONE NARCOTIC ANALGESIC TREZIX CAPSULE NASAL STEROIDS OPHTHALMIC ANTIHISTAMINE QNASL CHILDREN'S 40 MCG SPRAY FLONASE ALLERGY RELIEF SPRAY (OTC) NASACORT ALLERGY 24HR SPRAY (OTC) PAZEO 0.7% EYE DROPS ADD ST AND CROMOLYN KEOTIFEN AZELASTINE PRENATAL VITAMINS PRENATE PIXIE SOFTGEL PRENATAL VITAMINS BY MANUFACTURER: PRENATAL VITAMINS PRENATAL VITAMINS 21ST CENTURY HE, AMERISOURCEBERG, A-S,MEDICATION,AVKARE CHAIN DRUG,CHAIN DRUG CONS, CVS, EQUALINE VITAMINS, FREEDA VITAMINS,GOOD NEIGHBOR,KAISER FOUNDATI, KIRKMAN SALES,LEADER MAGNO-HUMPHRIES MAJOR PHARMACEU ME PHARM,MEDICINE SHOP NAT'L VIT. CO.,NNODUM CORP PD-RX PHARM,PLUS PHARMA;INC PRIME MARKETING,RITE AID CORP.,RUGBY,SUNMARK TODAY'S HEALTH; ACELLA PHARMACE AMNEAL PHARMACE BOCAGREENMD INC BRECKENRIDGE BUREL PHARMACEU CENTURION LABS,CYPRESS PHARM.,HEALTH MART,MACOVEN PREFERRED (CURRENT UTILIZERS WILL BE GRANDFATHERED) Listed above

Page 5 of 6 SKELETAL MUSCLE RELAXANTS PHARMAC,NATIONWIDE LABO PATRIN PHARMA,PHARMASSURE, PHARMAVITE,PRUGEN PHARMACE, PURETEK CORPORA R.A.MC NEIL CO.,SANCILIO & COMP,SETON PHARMACEU TRIGEN LABORATO,VIRTUS PHARMACE,VITAMEDMD WALGREEN CO.,WH NUTRITIONALS,ABBOTT NUTRITION,ACTAVIS U.S. BR ADVANCED MED AMBI PHARMACEUTICALS AVION PHARMACEUTICALS BAYER INC.,BOCA PHARMACAL CARWIN ASSOC.,CENTRIX PHARMAC,CONTRACT PHARM DISPENSING SOLN ECKSON LABS; LL,EVERETT G.M. PHARM,GIL PHARM JAYMAC PHARM KMM PHARMACEUTICALS LANNETT CO. INC,LASER; INC. LLORENS PHARM,MARNEL PHARM.,MEDA PHARMACEUTICALS MEDECOR PHARMA METHOD PHARMAC MIDLOTHIAN LABO, MISSION PHARM.,MJ NUTRITIONAL NIVAGEN PHARMACEUTICALS PAN AMERICAN,PFIZER CONS HLT PHARMICS,PHYSICIAN PARTN,PHYSICIANS TC. PRONOVA CORP,PRO-PHARMA LLC,PUBLIX SUPERMARKET R3 PHARMACEUTICALS ROCHESTER PHARM,SEYER INC. THERALOGIX; LLC TRIMARC LABORATORIES,UPSHER SMITH,US PHARMACEUTICALS VERTICAL PHARM,WOMEN'S CHOICE,XANODYNE PHARM ZERXIS PHARMA CYCLOBENZAPRINE ER 15 MG AND 30 TABLET CYCLOBENZAPRINE ER 30 MG TABLET CYCLOBENZAPRINE 7.5 MG TABLET CYCLOBENZAPRINE IR 5 MG AND 10 MG VITAMIN SUPPLEMENTS VP CH ULTRA SOFTGEL

Page 6 of 6 What action do I need to take? Please review these changes and work with your patients to transition them to formulary alternatives. If you determine preferred formulary alternatives are not clinically appropriate for specific patients, you will need to obtain prior authorization to continue coverage beyond the applicable effective date. What if I need assistance? We recognize the unique aspects of patients cases. If, for medical reasons, your patient cannot be converted to a formulary alternative, call our Pharmacy department at 1-866-398-1922 and follow the voice prompts for pharmacy prior authorization. You can find the preferred drug list on our provider website at www.anthem.com via the following steps: Select OTHER ANTHEM WEBSITES: Providers Under Providers Spotlight, select State Sponsored Plans Indiana Hoosier Healthwise and Healthy Indiana Plan Under State Sponsored Plans, select Indiana Hoosier Healthwise and Healthy Indiana Plan On the Provider Resources page, scroll down to Additional Programs and Services and select Pharmacy Information If you need assistance with any other item, contact your local Provider Relations representative or call Provider Services at 1-866-398-1922.