08/10/2010 Kit Components Product code AD0116 Description DELFIA EuTDA Cytotoxicity reagents Components: 13804319 BATDA Reagent, 50 ul 13804314 Europium solution 13804732 Lysis Buffer
Page 1/5 1 Identification of substance Product details Trade name: BATDA Reagent, 50 ul Product number: 13804319 Application of the substance / the preparation Laboratory chemicals Manufacturer/Supplier: PerkinElmer Life and Analytical Sciences 710 Bridgeport Avenue Shelton, CT 06484 Information department: Technical Support 800-762-4000 Emergency information: If inside, call CHEMTREC at 1-800-424-9300 If outside, call CHEMTREC at 1-703-527-3887 2 Composition/Data on components Chemical characterization Description: Mixture of the substances listed below with nonhazardous additions. Dangerous components: Void Additional Components 67-68-5 dimethyl sulfoxide Warning: 3.2/2, 3.3/2A <0.1% 1310-58-3 potassium hydroxide Danger: 3.2/1A <0.1% Warning: 3.1.O/4 3 Hazards identification Hazard description: Not applicable. Information pertaining to particular dangers for man and environment: The product does not have to be labelled due to the calculation procedure of international guidelines. Classification system: The classification was made according to the latest editions of international substances lists, and expanded upon from company and literature data. NFPA ratings (scale 0-4) 0 0 0 Health = 0 Fire = 0 Reactivity = 0 HMIS-ratings (scale 0-4) HEALTH FIRE REACTIVITY 0 0 0 Health = 0 Fire = 0 Reactivity = 0 GHS label elements Void 4 First aid measures General information: No special measures required. (Contd. on page 2)
Page 2/5 Trade name: BATDA Reagent, 50 ul After inhalation: Supply fresh air; consult doctor in case of complaints. After skin contact: Generally the product does not irritate the skin. After eye contact: Rinse opened eye for several minutes under running water. After swallowing: If symptoms persist consult doctor. (Contd. of page 1) 5 Fire fighting measures Suitable extinguishing agents: CO2, extinguishing powder or water spray. Fight larger fires with water spray or alcohol resistant foam. Protective equipment: No special measures required. 6 Accidental release measures Person-related safety precautions: Not required. Measures for environmental protection: Dilute with plenty of water. Measures for cleaning/collecting: Absorb with liquid-binding material (sand, diatomite, acid binders, universal binders, sawdust). Additional information: No dangerous substances are released. 7 Handling and storage Handling: Information for safe handling: No special measures required. Information about protection against explosions and fires: No special measures required. Storage: Requirements to be met by storerooms and receptacles: No special requirements. Information about storage in one common storage facility: Not required. Further information about storage conditions: None. 8 Exposure controls and personal protection Additional information about design of technical systems: No further data; see item 7. Components with limit values that require monitoring at the workplace: The product does not contain any relevant quantities of materials with critical values that have to be monitored at the workplace. Additional information: The lists that were valid during the creation were used as basis. Personal protective equipment: General protective and hygienic measures: The usual precautionary measures for handling chemicals should be followed. Breathing equipment: Not required. Protection of hands: The glove material has to be impermeable and resistant to the product/ the substance/ the preparation. Selection of the glove material on consideration of the penetration times, rates of diffusion and the degradation Material of gloves The selection of the suitable gloves does not only depend on the material, but also on further marks of quality and varies from manufacturer to manufacturer. As the product is a preparation of several substances, the resistance of the glove material can not be calculated in advance and has therefore to be checked prior to the application. (Contd. on page 3)
Page 3/5 Trade name: BATDA Reagent, 50 ul (Contd. of page 2) Penetration time of glove material The exact break through time has to be found out by the manufacturer of the protective gloves and has to be observed. Eye protection: Goggles recommended during refilling. 9 Physical and chemical properties General Information Form: Color: Odor: Change in condition Melting point/melting range: Undetermined. Boiling point/boiling range: Undetermined. Flash point: Not applicable. Fluid According to product specification Characteristic Auto igniting: Product is not selfigniting. Danger of explosion: Product does not present an explosion hazard. Density: Not determined. Solubility in / Miscibility with Water: ph-value: N/A Solvent content: Organic solvents: 0.0 % Fully miscible. 10 Stability and reactivity Thermal decomposition / conditions to be avoided: No decomposition if used according to specifications. Materials to be avoided: Dangerous reactions No dangerous reactions known. Dangerous products of decomposition: No dangerous decomposition products known. 11 Toxicological information Acute toxicity: Primary irritant effect: on the skin: No irritant effect. on the eye: No irritating effect. Sensitization: No sensitizing effects known. Additional toxicological information: The product is not subject to classification according to internally approved calculation methods for preparations: When used and handled according to specifications, the product does not have any harmful effects according to our experience and the information provided to us. (Contd. on page 4)
Page 4/5 Trade name: BATDA Reagent, 50 ul (Contd. of page 3) 12 Ecological information Other information: N/A 13 Disposal considerations Product: Recommendation: Smaller quantities can be disposed of with household waste. Uncleaned packagings: Recommendation: Disposal must be made according to official regulations. Recommended cleansing agent: Water, if necessary with cleansing agents. 14 Transport information DOT regulations: Hazard class: - Land transport ADR/RID (cross-border): ADR/RID class: - Maritime transport IMDG: IMDG Class: - Marine pollutant: No Air transport ICAO-TI and IATA-DGR: ICAO/IATA Class: - UN "Model Regulation": - Transport/Additional information: Not dangerous according to the above specifications. 15 Regulations Sara Section 355 (extremely hazardous substances): Section 313 (Specific toxic chemical listings): TSCA (Toxic Substances Control Act): All ingredients are listed. Proposition 65 Chemicals known to cause cancer: Chemicals known to cause reproductive toxicity for females: Chemicals known to cause reproductive toxicity for males: (Contd. on page 5)
Page 5/5 Trade name: BATDA Reagent, 50 ul Chemicals known to cause developmental toxicity: (Contd. of page 4) Cancerogenity categories EPA (Environmental Protection Agency) IARC (International Agency for Research on Cancer) NTP (National Toxicology Program) TLV (Threshold Limit Value established by ACGIH) NIOSH-Ca (National Institute for Occupational Safety and Health) OSHA-Ca (Occupational Safety & Health Administration) Product related hazard informations: Observe the general safety regulations when handling chemicals. The product is not subject to identification regulations according to directives on hazardous materials. 16 Other information The information provided in this is based on our present knowledge, and believed to be correct at the date of publication. However, no representation is made concerning its accuracy and completeness. It is intended as guidance only, and is not to be considered a warranty or quality specification. All materials may present unknown hazards, and should be used with caution. Although certain hazards are described, we cannot guarantee that these are the only hazards which exist. PerkinElmer Life and Analytical Sciences shall not be held liable for any damage resulting from handling or from contact with the product. Department issuing MSDS: EHS Contact: Technical Support 800-762-4000 Abbreviations and acronyms: ADR: Accord européen sur le transport des marchandises dangereuses par Route (European Agreement concerning the International Carriage of Dangerous Goods by Road) RID: Règlement international concernant le transport des marchandises dangereuses par chemin de fer (Regulations Concerning the International Transport of Dangerous Goods by Rail) IMDG: International Maritime Code for Dangerous Goods DOT: US Department of Transportation IATA: International Air Transport Association IATA-DGR: Dangerous Goods Regulations by the "International Air Transport Association" (IATA) ICAO: International Civil Aviation Organization ICAO-TI: Technical Instructions by the "International Civil Aviation Organization" (ICAO) GHS: Globally Harmonized System of Classification and Labelling of Chemicals ACGIH: American Conference of Governmental Industrial Hygienists NFPA: National Fire Protection Association () HMIS: Hazardous Materials Identification System ()
Page 1/6 1 Identification of substance Product details Trade name: Europium solution Product number: 13804314, C135-100 Application of the substance / the preparation Laboratory chemicals Manufacturer/Supplier: PerkinElmer Life and Analytical Sciences 710 Bridgeport Avenue Shelton, CT 06484 Information department: Technical Support 800-762-4000 Emergency information: If inside, call CHEMTREC at 1-800-424-9300 If outside, call CHEMTREC at 1-703-527-3887 2 Composition/Data on components Chemical characterization Description: Mixture of the substances listed below with nonhazardous additions. Dangerous components: 64-19-7 acetic acid Danger: 3.2/1A Warning: 2.6/3 1-2.5% Additional Components 7732-18-5 Water 75-100% 3 Hazards identification Hazard description: Not applicable. Information pertaining to particular dangers for man and environment: The product does not have to be labelled due to the calculation procedure of international guidelines. Classification system: The classification was made according to the latest editions of international substances lists, and expanded upon from company and literature data. NFPA ratings (scale 0-4) 0 0 0 Health = 0 Fire = 0 Reactivity = 0 HMIS-ratings (scale 0-4) HEALTH FIRE REACTIVITY 0 0 0 Health = 0 Fire = 0 Reactivity = 0 GHS label elements Void 4 First aid measures After inhalation: Supply fresh air; consult doctor in case of complaints. (Contd. on page 2)
Page 2/6 Trade name: Europium solution After skin contact: Immediately wash with water and soap and rinse thoroughly. After eye contact: Rinse opened eye for several minutes under running water. After swallowing: Seek medical treatment. (Contd. of page 1) 5 Fire fighting measures Suitable extinguishing agents: CO2, extinguishing powder or water spray. Fight larger fires with water spray or alcohol resistant foam. Protective equipment: Wear self-contained respiratory protective device. 6 Accidental release measures Person-related safety precautions: Wear protective clothing. Measures for environmental protection: Dilute with plenty of water. Measures for cleaning/collecting: Absorb with liquid-binding material (sand, diatomite, acid binders, universal binders, sawdust). Additional information: No dangerous substances are released. 7 Handling and storage Handling: Information for safe handling: No special measures required. Information about protection against explosions and fires: No special measures required. Storage: Requirements to be met by storerooms and receptacles: No special requirements. Information about storage in one common storage facility: Not required. Further information about storage conditions: None. 8 Exposure controls and personal protection Additional information about design of technical systems: No further data; see item 7. Components with limit values that require monitoring at the workplace: 64-19-7 acetic acid PEL REL TLV 25 mg/m³, 10 ppm Short-term value: 37 mg/m³, 15 ppm Long-term value: 25 mg/m³, 10 ppm Short-term value: 37 mg/m³, 15 ppm Long-term value: 25 mg/m³, 10 ppm Additional information: The lists that were valid during the creation were used as basis. Personal protective equipment: General protective and hygienic measures: The usual precautionary measures for handling chemicals should be followed. Breathing equipment: Not required. Protection of hands: The glove material has to be impermeable and resistant to the product/ the substance/ the preparation. Selection of the glove material on consideration of the penetration times, rates of diffusion and the degradation (Contd. on page 3)
Page 3/6 Trade name: Europium solution (Contd. of page 2) Material of gloves The selection of the suitable gloves does not only depend on the material, but also on further marks of quality and varies from manufacturer to manufacturer. As the product is a preparation of several substances, the resistance of the glove material can not be calculated in advance and has therefore to be checked prior to the application. Penetration time of glove material The exact break through time has to be found out by the manufacturer of the protective gloves and has to be observed. Eye protection: Goggles recommended during refilling. 9 Physical and chemical properties General Information Form: Color: Odor: Change in condition Melting point/melting range: 0 C (32 F) Boiling point/boiling range: 100 C (212 F) Flash point: Not applicable. Fluid According to product specification Characteristic Auto igniting: Product is not selfigniting. Danger of explosion: Product does not present an explosion hazard. Vapor pressure at 20 C (68 F): 23 hpa (17 mm Hg) Density at 20 C (68 F): 1 g/cm³ (8.345 lbs/gal) Solubility in / Miscibility with Water: ph-value: N/A Fully miscible. Solvent content: Organic solvents: 1.7 % Water: 98.3 % VOC content: 1.7 % 10 Stability and reactivity Thermal decomposition / conditions to be avoided: No decomposition if used according to specifications. Materials to be avoided: Dangerous reactions No dangerous reactions known. Dangerous products of decomposition: No dangerous decomposition products known. 11 Toxicological information Acute toxicity: Primary irritant effect: on the skin: May cause skin irritation. on the eye: May cause eye irritation. Sensitization: No sensitizing effects known. (Contd. on page 4)
Page 4/6 Trade name: Europium solution (Contd. of page 3) Additional toxicological information: The product is not subject to classification according to internally approved calculation methods for preparations: When used and handled according to specifications, the product does not have any harmful effects according to our experience and the information provided to us. 12 Ecological information Other information: N/A 13 Disposal considerations Product: Recommendation: Must be specially treated adhering to official regulations. Uncleaned packagings: Recommendation: Disposal must be made according to official regulations. Recommended cleansing agent: Water, if necessary with cleansing agents. 14 Transport information DOT regulations: Hazard class: - Land transport ADR/RID (cross-border): ADR/RID class: - Maritime transport IMDG: IMDG Class: - Marine pollutant: No Air transport ICAO-TI and IATA-DGR: ICAO/IATA Class: - UN "Model Regulation": - Transport/Additional information: Not dangerous according to the above specifications. 15 Regulations Sara Section 355 (extremely hazardous substances): Section 313 (Specific toxic chemical listings): TSCA (Toxic Substances Control Act): All ingredients are listed. Proposition 65 Chemicals known to cause cancer: (Contd. on page 5)
Page 5/6 Trade name: Europium solution Chemicals known to cause reproductive toxicity for females: Chemicals known to cause reproductive toxicity for males: Chemicals known to cause developmental toxicity: (Contd. of page 4) Cancerogenity categories EPA (Environmental Protection Agency) IARC (International Agency for Research on Cancer) NTP (National Toxicology Program) TLV (Threshold Limit Value established by ACGIH) NIOSH-Ca (National Institute for Occupational Safety and Health) OSHA-Ca (Occupational Safety & Health Administration) Product related hazard informations: Observe the general safety regulations when handling chemicals. The product is not subject to identification regulations according to directives on hazardous materials. 16 Other information The information provided in this is based on our present knowledge, and believed to be correct at the date of publication. However, no representation is made concerning its accuracy and completeness. It is intended as guidance only, and is not to be considered a warranty or quality specification. All materials may present unknown hazards, and should be used with caution. Although certain hazards are described, we cannot guarantee that these are the only hazards which exist. PerkinElmer Life and Analytical Sciences shall not be held liable for any damage resulting from handling or from contact with the product. Department issuing MSDS: EHS Contact: Technical Support 800-762-4000 Abbreviations and acronyms: ADR: Accord européen sur le transport des marchandises dangereuses par Route (European Agreement concerning the International Carriage of Dangerous Goods by Road) RID: Règlement international concernant le transport des marchandises dangereuses par chemin de fer (Regulations Concerning the International Transport of Dangerous Goods by Rail) IMDG: International Maritime Code for Dangerous Goods DOT: US Department of Transportation IATA: International Air Transport Association IATA-DGR: Dangerous Goods Regulations by the "International Air Transport Association" (IATA) ICAO: International Civil Aviation Organization ICAO-TI: Technical Instructions by the "International Civil Aviation Organization" (ICAO) GHS: Globally Harmonized System of Classification and Labelling of Chemicals ACGIH: American Conference of Governmental Industrial Hygienists NFPA: National Fire Protection Association () (Contd. on page 6)
Page 6/6 Trade name: Europium solution HMIS: Hazardous Materials Identification System () VOC: Volatile Organic Compounds (, EU) (Contd. of page 5)
Page 1/7 1 Identification of substance Product details Trade name: Lysis Buffer Product number: 13804732, AD0117, CR15-100 Application of the substance / the preparation Laboratory chemicals Manufacturer/Supplier: PerkinElmer Life and Analytical Sciences 710 Bridgeport Avenue Shelton, CT 06484 Information department: Technical Support 800-762-4000 Emergency information: If inside, call CHEMTREC at 1-800-424-9300 If outside, call CHEMTREC at 1-703-527-3887 2 Composition/Data on components Chemical characterization: CAS No. Description Nonhazardous Materials Identification number(s) N/A Chemical characterization Description: Mixture: consisting of the following components. Dangerous components: 11024-24-1 digitonin Danger: 3.1.O/2 25-50% Warning: 3.9/2 67-68-5 dimethyl sulfoxide Warning: 3.2/2, 3.3/2A 10-25% Additional Components 7732-18-5 Water 50-75% 3 Hazards identification Hazard description: Toxic Information pertaining to particular dangers for man and environment: Toxic if swallowed. Danger of cumulative effects. Classification system: NFPA ratings (scale 0-4) 4 0 0 Health = 4 Fire = 0 Reactivity = 0 (Contd. on page 2)
Page 2/7 Trade name: Lysis Buffer HMIS-ratings (scale 0-4) (Contd. of page 1) HEALTH FIRE REACTIVITY 4 0 0 Health = 4 Fire = 0 Reactivity = 0 GHS label elements Warning 3.9/2 - May cause damage to organs through prolonged or repeated exposure. Warning 3.1/4 - Harmful if swallowed. 3.2/2 - Causes skin irritation. 3.3/2A - Causes serious eye irritation. Prevention: Do not breathe dust/fume/gas/mist/vapours/spray. Wear protective gloves/protective clothing/eye protection/face protection. Response: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Specific treatment (see on this label). Take off contaminated clothing and wash before reuse. Disposal: Dispose of contents/container in accordance with local/regional/national/international regulations. 4 First aid measures After inhalation: Supply fresh air. Seek medical treatment. After skin contact: Immediately wash with water and soap and rinse thoroughly. After eye contact: Rinse opened eye for several minutes under running water. After swallowing: Seek immediate medical advice. 5 Fire fighting measures Suitable extinguishing agents: CO2, extinguishing powder or water spray. Fight larger fires with water spray or alcohol resistant foam. Protective equipment: Wear self-contained respiratory protective device. 6 Accidental release measures Person-related safety precautions: Wear protective clothing. Measures for environmental protection: No special measures required. Measures for cleaning/collecting: Absorb with liquid-binding material (sand, diatomite, acid binders, universal binders, sawdust). (Contd. on page 3)
Page 3/7 Trade name: Lysis Buffer Additional information: No dangerous substances are released. (Contd. of page 2) 7 Handling and storage Handling: Information for safe handling: Ensure good ventilation/exhaustion at the workplace. Information about protection against explosions and fires: No special measures required. Storage: Requirements to be met by storerooms and receptacles: No special requirements. Information about storage in one common storage facility: Not required. Further information about storage conditions: None. 8 Exposure controls and personal protection Additional information about design of technical systems: No further data; see item 7. Components with limit values that require monitoring at the workplace: 67-68-5 dimethyl sulfoxide WEEL 250 ppm Additional information: The lists that were valid during the creation were used as basis. Personal protective equipment: General protective and hygienic measures: The usual precautionary measures for handling chemicals should be followed. Breathing equipment: Use suitable respiratory protective device in case of insufficient ventilation. Protection of hands: The glove material has to be impermeable and resistant to the product/ the substance/ the preparation. Selection of the glove material on consideration of the penetration times, rates of diffusion and the degradation Material of gloves The selection of the suitable gloves does not only depend on the material, but also on further marks of quality and varies from manufacturer to manufacturer. Penetration time of glove material The exact break through time has to be found out by the manufacturer of the protective gloves and has to be observed. Eye protection: Goggles recommended during refilling. 9 Physical and chemical properties General Information Form: Color: Odor: Change in condition Melting point/melting range: Undetermined. Boiling point/boiling range: Undetermined. Flash point: Not applicable. Fluid According to product specification N/A Characteristic Danger of explosion: Product does not present an explosion hazard. (Contd. on page 4)
Page 4/7 Trade name: Lysis Buffer Density: Not determined. Solubility in / Miscibility with Water: ph-value: N/A Solvent content: Organic solvents: 0.0 % Not miscible or difficult to mix. (Contd. of page 3) 10 Stability and reactivity Thermal decomposition / conditions to be avoided: No decomposition if used according to specifications. Materials to be avoided: Dangerous reactions No dangerous reactions known. Dangerous products of decomposition: No dangerous decomposition products known. 11 Toxicological information Acute toxicity: Primary irritant effect: on the skin: Irritant to skin and mucous membranes. on the eye: Irritating effect. Sensitization: No sensitizing effects known. Additional toxicological information: When used and handled according to specifications, the product does not have any harmful effects according to our experience and the information provided to us. The substance is not subject to classification. 12 Ecological information Other information: N/A 13 Disposal considerations Product: Recommendation: Must be specially treated adhering to official regulations. Uncleaned packagings: Recommendation: Disposal must be made according to official regulations. (Contd. on page 5)
Page 5/7 Trade name: Lysis Buffer (Contd. of page 4) 14 Transport information DOT regulations: Hazard class: 6.1 Identification number: UN3287 Packing group: I Proper shipping name (technical name): TOXIC LIQUID, INORGANIC, N.O.S. (digitonin) Label 6.1 Land transport ADR/RID (cross-border): ADR/RID class: 6.1 Toxic substances Danger code (Kemler): 66 UN-Number: 3287 Packaging group: I Label: 6.1 Description of goods: 3287 TOXIC LIQUID, INORGANIC, N.O.S. (digitonin) Maritime transport IMDG: IMDG Class: 6.1 UN Number: 3287 Label 6.1 Packaging group: I EMS Number: F-A,S-A Marine pollutant: No Propper shipping name: TOXIC LIQUID, INORGANIC, N.O.S. (digitonin) Air transport ICAO-TI and IATA-DGR: ICAO/IATA Class: 6.1 UN/ID Number: 3287 Label 6.1 Packaging group: I Proper shipping name: TOXIC LIQUID, INORGANIC, N.O.S. (digitonin) UN "Model Regulation": UN3287, TOXIC LIQUID, INORGANIC, N.O.S., 6.1, I (Contd. on page 6)
Page 6/7 Trade name: Lysis Buffer (Contd. of page 5) 15 Regulations Sara Section 355 (extremely hazardous substances): Section 313 (Specific toxic chemical listings): TSCA (Toxic Substances Control Act): Proposition 65 Chemicals known to cause cancer: Chemicals known to cause reproductive toxicity for females: Chemicals known to cause reproductive toxicity for males: Chemicals known to cause developmental toxicity: Cancerogenity categories EPA (Environmental Protection Agency) IARC (International Agency for Research on Cancer) NTP (National Toxicology Program) TLV (Threshold Limit Value established by ACGIH) NIOSH-Ca (National Institute for Occupational Safety and Health) OSHA-Ca (Occupational Safety & Health Administration) Product related hazard informations: Observe the general safety regulations when handling chemicals. Hazard symbols: Toxic Hazard-determining components of labelling: digitonin Risk phrases: Toxic if swallowed. Danger of cumulative effects. (Contd. on page 7)
Page 7/7 Trade name: Lysis Buffer Safety phrases: When using do not eat or drink. Do not breathe gas/fumes/vapour/spray (appropriate wording to be specified by the manufacturer). In case of accident or if you feel unwell, seek medical advice immediately (show the label where possible). This material and its container must be disposed of as hazardous waste. (Contd. of page 6) 16 Other information The information provided in this is based on our present knowledge, and believed to be correct at the date of publication. However, no representation is made concerning its accuracy and completeness. It is intended as guidance only, and is not to be considered a warranty or quality specification. All materials may present unknown hazards, and should be used with caution. Although certain hazards are described, we cannot guarantee that these are the only hazards which exist. PerkinElmer Life and Analytical Sciences shall not be held liable for any damage resulting from handling or from contact with the product. Department issuing MSDS: EHS Contact: Technical Support 800-762-4000 Abbreviations and acronyms: ADR: Accord européen sur le transport des marchandises dangereuses par Route (European Agreement concerning the International Carriage of Dangerous Goods by Road) RID: Règlement international concernant le transport des marchandises dangereuses par chemin de fer (Regulations Concerning the International Transport of Dangerous Goods by Rail) IMDG: International Maritime Code for Dangerous Goods DOT: US Department of Transportation IATA: International Air Transport Association IATA-DGR: Dangerous Goods Regulations by the "International Air Transport Association" (IATA) ICAO: International Civil Aviation Organization ICAO-TI: Technical Instructions by the "International Civil Aviation Organization" (ICAO) GHS: Globally Harmonized System of Classification and Labelling of Chemicals ACGIH: American Conference of Governmental Industrial Hygienists CAS: Chemical Abstracts Service (division of the American Chemical Society) NFPA: National Fire Protection Association () HMIS: Hazardous Materials Identification System ()