A Survey on Detection and Classification of Brain Tumor from MRI Brain Images using Image Processing Techniques

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A Survey on Detection and Classification of Brain Tumor from MRI Brain Images using Image Processing Techniques Shanti Parmar 1, Nirali Gondaliya 2 1Student, Dept. of Computer Engineering, AITS-Rajkot, Gujarat, India 2Assistant Professor, Dept. of Computer Engineering, AITS-Rajkot, Gujarat, India ---------------------------------------------------------------------***--------------------------------------------------------------------- Abstract - Brain tumor is an abnormal growth of brain cells within the brain. Brain tumor detection and segmentation and is one of the most challenging and time consuming task in medical image processing. MRI (Magnetic Resonance Imaging) is a visualization medical technique, which provides plentiful information about the human soft tissue, which helps in the diagnosis of brain tumor. The detection of brain tumor is complicated procedures in medical field. The algorithm incorporates steps for pre processing, image segmentation, feature extraction and image. Various data mining algorithms like k-means, SVM, FCM, k-nearest neighbor, neural network used for this purpose. In this review paper, the review of different brain tumor methods using the MR with pros and cons are given. It also gives comparative study of all the reviewed methods. Key Words: Brain Tumor, Classification, Disease Identification, Magnetic Resonance Imaging (MRI),, Tumor Detection. 1. INTRODUCTION detection and of brain cancer, based on common practices. Most of the technicians are slow, less responsible, and that's hard to quantify possess a degree of subjectivity. Detection of brain tumor from MRI involves various Phases such as Preprocessing, Feature extraction, and. Fig 1 shows different stages in brain tumor detection. Image Preprocessing techniques are applied to improve the quality of image [12]. Brain is the center of human central nervous system. The brain is a complex organ as it contains 50-100 billions neurons forming a gigantic network. A brain tumor is a mass of unnecessary and abnormal cell growing in the brain or it can be defined as an intracranial lesion which occupies space within the skull and tends to cause a rise in intracranial pressure. Brain tumors are mainly classified into two i.e. Benign and Malignant. Benign tumors are noncancerous and they seldom grows back where as malignant tumors are cancerous and they rapidly grows and invade to the surrounding healthy brain tissue. In medical practices, the early detection and recognition of brain tumors accurately is very vital. In literature, there are many techniques has been proposed by different researchers for the accurate segmentation of brain tumor. Some discoveries such as X-rays, ultrasound, radioactivity, magnetic resonance imaging (MRI) or computed tomography and the development of tools that can generate medical have facilitated the development of some of the most efficient exploration tools in medicine [11]. Magnetic resonance imaging (MRI) is high-quality medical imaging, particularly for brain imaging. MRI inside the human body is helpful to see the level of detail. Doctors have major technical and economic importance of reliable and fast Fig -1: Stages in Brain Tumor Detection MRI Image segmentation is based on set of process of brain tumor detection; pixel intensity based features are extracted. Image group pixels into regions and hence defines the object regions. uses the features extracted from image. Classification is the last step in process of brain tumor image into normal or abnormal and classifies the abnormality type whether it is benign or malignant. This study evaluates various techniques which are used in tumor detection from brain MRI. In this paper we are aiming to take review of different methods of brain tumor image segmentation. We are aiming to present the different MRI segmentation methods and provide comparative study of all methods. 2. LITERATURE SURVEY Objective of this review section is to present literature survey of image segmentation methods. The main goal is to highlight advantages and limitations of these methods. Key image 2018, IRJET Impact Factor value: 6.171 ISO 9001:2008 Certified Journal Page 162

processing techniques for brain MRI image segmentation is classified as k-means, SVM, FCM, k-nearest neighbor, neural network, adaboost, genetic and other methods etc. Parveen, Amritpal singh [2] purposed algorithm is a combination of SVM and fuzzy c-means, a hybrid technique for prediction of brain tumor. Here, the image is enhanced using contrast improvement, and mid-range stretch. Double thresholding and morphological operations are used for skull striping. Fuzzy c-means (FCM) clustering is used for the image segmentation. Grey level run length matrix (GLRLM) is used for extraction of feature. Then, Linear, Quadratic and Polynomial SVM technique is applied to classify the brain MRI. Real data set of 120 patients MRI brain have been used to detect 'tumor' and 'non-tumor' MRI. The SVM classifier is trained using 96 brain MRI, after that the remaining 24 brain MRI was used for testing the trained SVM. SVM classifier with Linear, Quadratic and Polynomial kernel function give 91.66%, 83.33% and 87.50% accuracy respectively and 100% specificity. Astina minz, Prof. Chandrakant Mahobiya [8] proposed an effective automatic method for brain MRI is projected using the Adaboost machine learning algorithm. The proposed system consists of three parts such as Preprocessing, Feature extraction and Classification. Preprocessing has removed noise in the raw data, it transform RGB image into grayscale, median filter and thresholding segmentation is applied. For feature extraction by using GLCM technique 22 features were extracted from an MRI. For boosting technique used (Adaboost). It gives 89.90% accuracy and result in normal brain or in Malignant or Benign type of tumor. In future work, we can work of quadratic and polynomial kernel function. The accuracy of the system will be increased by increasing training database. Also the system can be implement for different types of classes like Glioma and Meningioma. Garima Singh, Dr. M.A. Ansari [9] proposed, a novel technique which includes Normalization of Histogram and K-means. First, input image is pre-processed in order to remove the unwanted signals or noise from it. To de-noise filters such as Median filter, Adaptive filter, Averaging filter, Un-sharp masking filter and Gaussian filter is used in the MRI. The histogram of the pre-processed image is normalized and of MRI is done. Finally, the image is segmented using K-means algorithm in order to take out the tumor from the MRI. Efficient of the MRIs is done using NB Classifier and SVM so as to provide accurate prediction and. Naive Bayes and SVM Classifier give accuracy 87.23% and 91.49% respectively. SVM give better accuracy. For implementation MATLAB is used. The proposed method has some limitations that it could not find out the precise or accurate boundary of the tumor region. In the future, improvement in the proposed algorithm can be done by working on the limitations, the quality of the output can be improved by using better morphological operations. G Rajesh Chandra, Dr. Kolasani Ramchand, H Rao [4] proposed method in that MRI image of brain is de-noised using DWT by thresholding of wavelet co-efficient. Genetic algorithm is applied to detect the tumor pixels. A genetic algorithm is then used in order to determine the best combination of information extracted by the selected criterion. The present approach uses k-means clustering methods into Genetic Algorithms for guiding this last Evolutionary Algorithm in his search for finding the optimal or sub-optimal data partition. This method achieved segmentation accuracy from 82 percent to 97 percent of detected tumor pixels based on ground truth. The limitation of this work is that wavelet transform require large storage and its computational cost is high. Mukambika P. S., Uma Rani K. [1] Proposed Methodology in which Image is processed through: Preprocessing,, Feature extraction Classification stages. In preprocessing, Morphology technique using double thresholding is applied to remove the skull out of the MRI brain. The present work presents the comparison study of two techniques used for tumor detection of MRI. One is based on the Level set method that uses the non parametric deformable models with active contour to segment the brain tumor from the MRI brain. The other one is the K-means segmentation algorithm. After the segmentation decision making is performed in two stages: Feature extraction using Discrete Wavelet Transform and Gray Level Co-occurrence Matrix, and using the Support Vector Machine. Dataset of MRI brain tumor includes T2 weighted 17 benign and 24 malignant tumor of different patients. SVM with Level Set and K-Means segmentation classify image into normal brain, benign or Malignant tumor with 94.12% and 82.35% accuracy respectively. Level Set method gives better results than k- means segmentation. K. Sudharani, Dr. T. C. Sarma, Dr. K. Satay Rasad [6] Proposed Methodology include methods like Histogram, Re-sampling, K-NN Algorithm, Distance Matrix. First, Histogram gives the total number of specified value of pixels distributed in a particular image. Re-sampling re-size image to 629X 839 for proper geometrical representation. Classification and identification of brain tumor by using k-nn which is based on training of k. In this work Manhattan metric has applied and calculated the distance of the classifier. The algorithm has been implemented using the Lab View. Algorithm has been tested on 48. The identification score for all are about 95%. Ketan Machhale, Hari Babu Nandpuru2, Vivek Kapur3, Laxmi Kosta [13] proposes an intellectual system to recognize normal and abnormal MRI brain. Under these techniques, image preprocessing, image feature extraction and subsequent of brain cancer is successfully performed. In pre-processing MRI brain RGB 2018, IRJET Impact Factor value: 6.171 ISO 9001:2008 Certified Journal Page 163

are converted in grey scale image. Median Filter is applied to remove noise from mri image. Then Skull Masking is use to remove non-brain tissue from MRT brain image. Dilation and erosion are two elementary morphological operations used for skull masking. In feature extraction symmetrical, gray scale and texture features are extracted. When different machine learning techniques: Support Vector Machine (SVM), K- Nearest Neighbor (KNN) and Hybrid Classifier (SVM-KNN) is used to classify 50, it is observed from the results that the Hybrid classifier SVM-KNN demonstrated the highest accuracy rate of 98% among others. Rasel Ahmmed, Anirban Sen Swakshar, Md. Foisal Hossain, Md. Abdur Rafiq[14] proposed method which include stages like image pre-processing, segmentation, feature extraction, SVM and tumor stage using Artificial Neural Network(ANN). In pre-processing three contrast enhancement techniques like adjusted, adaptive threshold and histogram imaging using both weiner2 and median2 filter is applied. is done by TKFCM algorithm which is integration of the K-means and Fuzzy c-means with some modification. Feature extraction is done in two orders. In First order statistic features and in Second order region property based statistic features are derived. Then SVM classify brain MRI image into normal or tumor brain. Brain Tumor stage is classified by ANN classifier. The number of the used data for each MRI image of normal brain, malignant tumor, and benign tumor is obtained from 39 where 3 normal, 9 benign, 17 malignant I, 6 malignant II, 3 malignant II, and 1 malignant IV stage tumor brain MRI. The accuracy of proposed method is 97.44%. 3. COMPARATIVE STUDY OF DIFFERENT BRAIN TUMOR DETECTION AND CLASSIFICATION TECHNIQUES USING MRI IMAGES Comparative study of different brain tumor Detection and Classification techniques are summarized in compare table (Table I) with advantages and disadvantages. Most of the key features of methods are mentioned in Table I with respective limitations and benefits that make our work unique. Table -1: Comparison of Brain tumor detection and techniques-i Author Title Proposed Technique Parveen, Amritpal singh Astina Minz, Prof. Chndrakant Mahobiya Detection of brain tumor in MRI, using combination of FCM and SVM MR Image using Adaboost for brain tumor type FCM Adaboost & Neural Algorithms Dataset 120 MRI 50 MRI Garima Singh, Dr. M. A. Ansari tg Rajesh Chandra, Dr. Ramchand H Rao Mukambika P. S., Uma Rani K. K.Sudharani, Dr.T. Sarma, Dr. K. Rasad Ketan Machhale, Hari Babu Nandpuru, VivekKapur, Laxmi Kosta Rasel Ahmmed, Anirban Sen Swakshar, Md. Foisal Hossain, Md. Abdur Rafiq Efficient Detection of Brain Tumor from MRIs Using K-Means and Normalized Histogram Tumor detection in brain using genetic algorithm and Classification of MRI Brain Tumor Intelligent Brain Tumor Lesion Classification and Identification from MRI Images Using k- NN Technique MRI Brain Cancer Classification Using Hybrid Classifier (SVM- KNN) Classification of Tumors and It Stages in Brain MRI Using Support Vector Machine and Artificial Neural Network K-Means &Naïve Bayes DWT Filtering + Genetic Algorithm Level set method & k- Means classifier K Nearest Neighbor SVM & SVM- KNN TKFCM + SVM Classification + ANN 110 MRI 100 MRI 41 MRI 48 MRI 50 MRI 39 MRI Table -2: Comparison of Brain tumor detection and techniques-ii Author Accuracy Benefits Limitations Parveen, Amritpal singh Astina Minz, Prof. Chndrakant Mahobiya Garima Singh, Dr. M. A. Ansari 91.66% It combines clustering and algorithm Efficient method 89.90% & 74.00% 91.49 & 87.23% Minimize the error, Less time consuming Accurate results. Fast & efficient in Brain tumor type can t be classified Difficult to choose SVM kernel function It can maximize the margin with respect to features that have already been selected. It doesn t work well with clusters (in the original 2018, IRJET Impact Factor value: 6.171 ISO 9001:2008 Certified Journal Page 164

term of computational time and cost T.G. Rajesh Chandra, Dr. Ramchand H Rao Mukambika P. S., Uma Rani K. K.Sudharani, Dr.T. Sarma, Dr. K. Rasad Ketan Machhale, Hari Babu Nandpuru, VivekKapur, Laxmi Kosta Rasel Ahmmed, Anirban Sen Swakshar, Md. Foisal Hossain, Md. Abdur Rafiq 90.00% Uses the ability of GA to solve optimization problems with large data set 94.12% & 82.35% 4. CONCLUSIONS Increased Accuracy and Robust modeling 95.00 % Simple and flexible to implement, Handle multiclass cases 98.00% Handle multiclass cases Increased Accuracy 97.44%. Increased Accuracy Classify brain tumor with brain tumor affected stages input data) of different size and Different density Wavelet transform require large storage and its computational cost is high. Potential of misidentificat-ion of what is supposed to be categorized Large search problem to find nearest neighbor Storage of data When there is a change in dataset, fresh training dataset is required. Difficulty in selecting optimal features to distinguish different classes Time Consuming In this paper we have accomplished a partial survey of various techniques for MRI brain image as well their advantages and disadvantages. A comparative study is made on various techniques. After evaluation of well-known technique it is clearly shown the various methods which can detect the tumor efficiently and provide accurate result. Though some algorithms producing accurate and reasonable results, at the same time they are having some limitations like it is not suitable for large data set and having longer computation time. One of the principal reasons might be the lack of standardized procedures. Computational time will also be considered to compare this technique efficiently. As the diagnosis tumor is a complicated and sensitive task, accuracy and reliability are always assigned much importance. For the future work we suggest to present more accurate, efficient as well as faster method for early detection and of brain tumors. ACKNOWLEDGEMENT I would like to thank the all faculty members of the Institute who helped us lot in calculating the facts and Figures related to this review paper. I would also like to thank the researcher whom research on this field, provide important references for my paper. I am also thankful to all reviewers who gave their helpful review. REFERENCES [1] Mukambika P. S., Uma Rani K. and Classification of MRI Brain Tumor in International Research Journal of Engineering and Technology (IRJET) Volume: 04 Issue: 07 July -2017 [2] Parveen, Amritpal Singh Detection of Brain Tumor in MRI Images, using Combination of Fuzzy c-means and SVM in 2nd International Conference on Signal Processing and Integrated Networks (SPIN) 2015 [3] Sathees B. Kumar, Dr. Anbu R. Selvi Feature Extraction Using Image Mining Techniques to Identify Brain Tumors in IEEE Sponsored 2nd International Conference on Innovations in Information Embedded and Communication Systems ICIIECS 2015 [4] G Rajesh Chandra, Dr. Kolasani Ramchand H Rao TUMOR DETECTION IN BRAIN USING GENETIC ALGORITHM in 7th International Conference on Communication, Computing and Virtualization 2016 [5] Sanjana Chawla, Rajiv Sharma Application of Data Mining in Bioinformatics in International Journal of Engineering Science and Computing, June 2016 [6] K. SUDHARANI, Dr. T. C. SARMA, Dr. K. SATYA RASAD Intelligent Brain Tumor Lesion Classification and Identification from MRI Images Using k-nn Technique in International Conference on Control, lnstrumentation, Communication and Computational Technologies (lccicct) 2015 [7] Ashraf M. Said, Fatma S. Ibrahim Comparative Study of Techniques for Detection of Tumors Based on MRI Brain Images in International Journal of Bioscience, Biochemistry and Bioinformatics Issue September 2017 [8] Astina Minz, Prof. Chanddrakant Mahobiya MR Image using Adaboost for brain tumor type in IEEE 7th International Advance Computing Conference (IACC) 2017 [9] Garima Singh, Dr. M. A. Ansari Efficient Detection of Brain Tumor from MRIs Using K-Means and Normalized Histogram in IEEE Issue 2016 [10] S.U.ASWATHY, Dr G.GLAN DEVA DHAS, Dr. S.S.KUMAR A Survey on Detection of Brain Tumor from MRI Brain Images in International Conference on Control, Instrumentation, Communication and Computational Technologies (ICCICCT) 2014 2018, IRJET Impact Factor value: 6.171 ISO 9001:2008 Certified Journal Page 165

[11] Ruchi D., Deshmukh et al Study of Different Brain Tumor MRI Image Techniques in International Journal of Computer Science Engineering and Technology( IJCSET) Vol 4, Issue 4,133-136 April 2014 [12] Mr.Deepak.C.Dhanwani, Prof. Mahip M.Bartere Survey on Various Techniques of Brain Tumor Detection from MRI Images in International Journal of Computational Engineering Research Vol, 04 Issue, 1 Issn 2250-3005, January-2014 [13] Ketan Machhale, Hari Babu Nandpuru, Vivek Kapur, Laxmi Kosta MRI Brain Cancer Classification Using Hybrid Classifier (SVM-KNN) in international conference on instrumentation and control (ICIC) MAY 28-30, 2015. [14] Rasel Ahmmed, Anirban Sen Swakshar, Md. Foisal Hossain, and Md. Abdur Rafiq Classification of Tumors and It Stages in Brain MRI Using Support Vector Machine and Artificial Neural Network in International Conference on Electrical, Computer and Communication Engineering (ECCE), Cox s Bazar, Bangladesh, February 16-18, 2017 2018, IRJET Impact Factor value: 6.171 ISO 9001:2008 Certified Journal Page 166