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COMMUNICABLE DISEASEE REPORT Quarterly Report Volume 32, Number 1 2014 Year End Summary March 2015 Hepatitis C in Newfoundland and Labrador Page 1 Enteric Outbreaks in 20144 Page 2 Vaccine Coverage Rates 2013 14 Page 4 Ebola Virus Disease (EVD) Preparedness Page 7 Year End Disease Report December 2014 Page 9 Hepatitis C in Newfoundland and Labrador Hepatitis C is a liver infection caused by a blood borne virus called the hepatitis C virus (HCV). It is estimated that between 2 3% of the world s population are infected with HCV (WHO, 2010). Nationally, about 0.8% of the population is estimated to have HCV (Remis, 2007). Over the past two years there has been an increase in laboratory confirmed cases of HCV in Newfoundland and Labrador. There were 128 laboratory confirmed cases of HCV reported in 2014 (Figure 1) ). A sharp increase was observed from 2012 (68 cases) to 2013 (106 cases). Case counts range from as low as 22 in 1994 to as high as 128 in 2014. Each year, more males were diagnosed with HCV than females in Newfoundland and Labrador. In 2014, approximately 61% of confirmed cases were male. The mean age of cases at the time of diagnosis was 34..4 years in 2014. 1

Number of Laboratory Confimed Cases 140 120 100 80 60 40 20 0 Male Female 34 34 33 36 50 22 30 29 12 31 22 18 16 31 28 27 35 33 28 33 29 37 50 52 61 60 68 56 70 78 10 7 12 15 14 22 25 26 26 11 14 11 7 11 6 37 37 42 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 2003 2004 2005 2006 2007 2008 2009 2010 2011 2012 2013 2014 Year of Diagnosis Figure 1: Number of Laboratory Confirmed Cases of Hepatitis C in NL, by Sex, 1991 2014 Source: Communicable Disease Surveillance System, Department of Health and Community Services Figure 2 presents the rate per 100,000 population of laboratory confirmed cases of HCV. The rate ranges from 3.8 per 100,000 in 1994 to 24.3 per 100,000 in 2014. Similar to case counts, a sharp increase was also observed in the rate of cases from 2012 to 2014 (12.9 per 100,000 to 24.3 per 100,000). Rate per 100,000 population 30.0 25.0 20.0 15.0 10.0 5.0 0.0 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 2003 2004 2005 2006 2007 2008 2009 2010 2011 2012 2013 2014 Rate 7.4 5.5 5.0 3.8 6.7 7.1 7.6 9.1 8.3 8.0 8.4 6.9 11.4 13.9 15.9 18.6 18.5 19.7 16.4 11.9 12.0 12.9 20.1 24.3 Year of Diagnosis Figure 2: Rate of Laboratory Confirmed Cases of Hepatitis C in NL, 1991 2014 Source: Communicable Disease Surveillance System, Department of Health and Community Services References Remis R. Modelling the incidence and prevalence of hepatitis C infection and its sequelae in Canada, 2007 final report. Public Health Agency of Canada. 2007. World Health Organization (WHO). Viral Hepatitis Resolutions from the 63rd World Health Assembly. 2010. 2

Enteric Outbreaks 2014 Enteric outbreaks are reported using the enteric, foodborne and waterborne disease module of the Canadian Network for Public Health Intelligencee (CNPHI) Outbreak Summaries application. From January 1, 2014 to December 31, 2014 there were 45 enteric outbreaks in Newfoundland and Labrador. Seventeenn of these outbreaks occurred in Eastern Health, 155 in Central Health, 9 in Western Health and 4 in Labrador Grenfell Health (Figure 3). These numbers are similar to previous years. Figure 3: Number of Enteric Outbreaks by Regional Health Authority, 2014 Source: Canadian Network for Public Health Intelligencee (CNPHI) Of the 45 outbreaks, 37 (82.2%) were transmitted throughh person to person contact (Figure 4). Two outbreaks were identified as foodborne and six were of unknown transmission type. Figure 4: Primary Mode of Transmission, Enteric Outbreaks, NL, 2014 Source: Canadian Network for Public Health Intelligencee (CNPHI) 3

The majority (64%) of outbreaks occurred at long term care settings (including personal care homes) (Figure 5) ). Outbreaks at schools and hospitals accounted for 13% and 11% of outbreaks, respectively. Enteric outbreaks were also reported at daycares/day homes (5%), catered events (5%) and other community settings (2%). Figure 5: Setting of Enteric Outbreaks, NL, 2014 Source: Canadian Network for Public Health Intelligencee (CNPHI) Vaccine Coveragee Newfoundland and Labrador has benefited from the high coverage ratess for the childhood and school to the based programs (Table 1). Figures 7, 8 and 9 outline the programs and coverage as compared national goal. Table 1: Vaccines used in the 2014 Newfoundland and Labradorr Childhood Programs Age 2 months 4 months 6 months 6 months and older 12 months 18 months 4-6 years Vaccine DTaP-IPV-Hib, Pneu C-133 DTaP-IPV-Hib, Pneu C-133 DTaP-IPV-Hib Inf (Fall & Winter only) Pneu C-13, MMR-Var andd Men-C-C DTaP-IPV-Hib and MMR-Var DTaP-IPV or Tdap-IPV 4

Grade 4 Grade 6 Grade 9 Men-C-ACYW-135 HB HPV (females only) Tdap KEY for abbreviations: DTaP IPV Hib: protects against diphtheria, tetanus, pertussis, polio and Haemophilus influenza b DTaP IPV: protects against diphtheria, tetanus, pertussis and polio Tdap IPV: protects against tetanus, diphtheria, pertussis and polio Pneu C 13: protects against 13 types of pneumococcal disease Inf: protects against influenza Men C C: protects against type C meningococcal disease Men C ACYW 135 protects against type A, C, Y and W 135 meningococcal disease MMRV: protects against measles, mumps, rubella, & varicella (chickenpox) HB: protects against hepatitis B (2 doses given over a 6 month period) HPV: protects against human papillomavirus (cervical cancer) (3 doses given over a 6 month period) Tdap: protects against tetanus, diphtheria and pertussis 100.0 National Goal Coverage Rate (%) 95.0 90.0 85.0 80.0 75.0 70.0 DTaP-IPV/HiB Pneumococcal MMR MMRV Men-C Eastern 97.0 98.0 96.0 98.0 98.0 Central 98.2 98.2 98.5 98.3 98.9 Western 99.0 99.0 99.0 99.0 100.0 Lab-Gren 99.7 100.0 99.2 100.0 100.0 Prov Avg. 98.5 98.8 98.2 98.8 99.2 Figure 7: Age 2 Years Vaccine Coverage Rates, 2013-2014 5

National Goal 100 Coverage Rate (%) 95 90 85 80 75 70 DTaP-IPV/HiB DTaP-IPV Pneumococcal MMR Men C Varicella Eastern 94 91 92 94 93 94.0 Central 97.1 94.0 96.6 97.5 97.4 97.3 Western 98.0 98.0 98.0 98.5 99.0 98.0 Lab-Gren 98.0 93.4 98.3 98.8 99.0 98.3 Prov Avg. 96.8 94.1 96.2 97.2 97.1 96.9 Figure 8: Kindergarten Age 4-6 Years Vaccine Coverage Rates, 2013-2014 Coverage Rate (%) National Goal 100 95 90 85 80 75 70 HPV 1 HPV 2 HPV 3 Hep B-Dose 1 Hep B-Dose 2 Eastern 90 93.0 90.0 97.0 94.0 Central 96.3 95.3 93.3 98.1 95.5 Western 92 91.0 88.0 96.0 94.0 Lab-Gren 93 95.6 83.4 93.8 83.6 Prov Avg. 92.8 93.7 88.7 96.2 91.8 Figure 9: Grade Six Vaccine Coverage Rates, 2013-2014 The immunization coverage rates for the grade 4 meningococcal A, C, Y W 135 and the grade 9 Tdap were 96.8% and 93.1%, respectively. 6

Immunization Programs and Vaccine Preventable Disease (VPD) The VPDs continue to be reported at very low numbers. The 13 cases of hepatitis B are between 24 to 58 years of age. The majority of which are in the non immunized population. Of the 10 pertussis cases the age range was 1 month to 44 years of age. Chickenpox circulated throughout 2014, most cases were 10 years of age and under. A second dose has been offered to all children born in 2013 and after. There were 2 cases of invasive Hib. Ebola Virus Disease (EVD) Preparedness in Newfoundland and Labrador There have been 27, 442 case reports of EVD and 11,220 deaths reported from the outbreak in West Africa between January 01 to June 28, 2015. Three countries have the majority of the cases: Guinea, Liberia and Sierra Leone. On September 30, 2015 the first case reported in North America created a sense of urgency in the preparation for a possible case in Canada. In Newfoundland and Labrador, the Department of Health and Community Services rose to this challenge and in October a Provincial Ebola Coordinating Committee (ECC) was engaged, led by the Deputy Minister of Health. Eight task groups were formed to focus on different areas of preparedness, including: Emergency Health Planning Infection Prevention and Control (IPAC) Waste Management Public Health Measures Human Resources Communications Paramedicine/transportation Ethics In each Regional Health Authority (RHA) similarly structured committees were established and followed principles of emergency incident management. In a very short time an all encompassing plan had been established for the management of a suspect or confirmed case of EVD. Two designated care centers were recognized, the Intensive Care Units at the General Hospital and the Janeway Hospital. Guidelines were developed for the protection of healthcare workers (HCWs) caring for the patient with EVD and the appropriate management of infectious waste. A plan was established for the transportation of the patient whether by road or air. Approximately four thousand HCWs were trained on enhanced IPAC measures required for the care of patients with EVD. Over the fall 2014 table top exercises and full scale exercises (to simulate a real event as closely as possible) were used to test the preparedness of the RHAs. In February 2015 the efforts of the Provincial ECC and the Regional ECC were recognized by the Public Health Agency of Canada s Ebola Rapid Response Team as having one of the most comprehensive provincial plans for caring for a patient with EVD. For more information on EVD see the Government of Newfoundland and Labrador website: http://www.health.gov.nl.ca/health/comm_diseases.html 7

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