IAEA/RCA Regional Training Course on Theragnostics and Dementias

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IAEA/RCA Regional Training Course on Theragnostics and Dementias

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International Atomic Energy Agency Department of Technical Cooperation And Nuclear Medicine and Diagnostic Imaging Section Division of Human Health TN-RAS6083-1702276 IAEA/RCA Regional Training Course on Theragnostics and Dementias December 4-8, 2017 Osaka University Graduate School of Medicine, Local Course Director HATAZAWA, Jun Osaka University Graduate School of Medicine Department of Nuclear Medicine and Tracer Kinetics 565-0871 Osaka Japan Tel: 81668793461 Fax: 81668793469 E-mail: hatazawa@tracer.med.osaka-u.ac.jp IAEA TECHNICAL OFFICER Mr. PASCUAL Thomas NB PROGRAM

Monday 4 December 2017 AM: Cancer board hall (Oncology center 5F) PM: Multimedia hall (CoMIT 1F) 10:00-10:30 Opening remarks Pre-Course Evaluation SESSION 1 Pascual, Thomas (Technical Officer, IAEA) Prof. Jun Hatazawa Course Director Chair: Dr. Frederik Giesel University Hospital Heidelberg Heidelberg, Germany 10:30-11:20 Introduction of theragnostics 1. Review the concept and overview of theragnostics. 2. Understand the basic principle of BNCT. 11:20-12:00 Basic principle of theragnostics 1. Recognize the significance of radiopharmaceuticals used in theragnostics. Prof. Jun Hatazawa Dr. Toru Shiga Hokkaido University, Sapporo, Japan 2. Integrate the concepts discussed in relation to best practices of theragnostics. 12:00-13:30 Lunch Break 13:30-14:20 Theragnostics: Neuroendocrine tumors and SPECT imaging for neuroendocrine tumors. Dr. Yuji Nakamoto, Kyoto University, Kyoto, Japan the therapy using radiopharmaceuticals for neuroendocrine tumors. End of session 1

SESSION 2 Chair: Prof. Jun Hatazawa 14:30-15:20 Brain perfusion SPECT for dementia 1. Summarize the radiopharmaceuticals and typical findings of each dementia in brain perfusion imaging. Dr. Hiroshi Matsuda National Center of Neurology and Psychiatry, Tokyo, Japan 15:20-15:40 Coffee Break 2. Recognize the typical pattern of dementia SPECT. 15:40-16:20 Statistical Parametric Analysis in Nuclear Medicine 1. Discuss the utilization of statistical image analysis in dementia. Dr. Hiroki Kato 2. Recognize the limitations of statistical image analysis and importance of visual analysis. 16:20-17:00 Case presentation of Brain perfusion SPECT 1. Discuss the key point of SPECT image interpretation in dementia. Prof. Eku Shimosegawa 2. Recognize the limitations of statistical image analysis and importance of visual analysis. End of session 2 17:30- Welcome Reception (Venue: Minerva, Second floor of Icho Kaikan)

Tuesday, 5 December 2017 AM: Multimedia hall (CoMIT 1F) PM: Cancer board hall (Oncology center 5F) SESSION 3 09:00-12:00 Parametric image analysis of brain images (including software practice): 1. Describe appropriate ways of report writing in neurological cases with CT or MR interpretation. Dr. Tadashi Watabe Dr. Hiroki Kato 12:00-13:00 Lunch Break 2. Discuss the role of Brain Imaging using clinical cases for image interpretation and its relevance in clinical practice. End of session 3 SESSION 4 Chair: Dr. Pascual, Thomas (Technical Officer, IAEA) 13:00-13:30 Theragnostics: Neuroendocrine tumors (2) 1. Recognize the radiopharmaceuticals used in diagnosis and radionuclide therapy for neuroendocrine tumors. 2. Learn from the clinical case presentation of DOTATOC imaging and Lu-Therapy. 13:30-14:20 Alzheimer s Disease 3. Understand the pathophysiology of Alzheimer s disease. Dr. Frederik Giesel (University Hospital Heidelberg, Heidelberg, Germany) Prof. Kazunari Ishii (Kinki University, ) 4. Discuss the role of nuclear medicine imaging in Alzheimer s diseases.

14:20-15:10 PET and SPECT in Dementias (other than Alzheimer s disease) 1. Understand the pathophysiology of dementias. Dr. Takashi Kato (National Center for Geriatrics and Gerontology, Aichi, Japan) 15:10-15:30 Coffee Break 2. Discuss the role of nuclear medicine imaging in dementias. 15:30-16:10 Case presentation of PET and SPECT about dementia (1) 1. Recognize the utility of PET and SPECT probes in dementias. Prof. Hiroshi Toyama (Fujita Health University, Aichi, Japan) 2. Discuss the role of PET and SPECT imaging in dementias. 16:10-16:50 Case presentation of PET and SPECT about dementia (2) 1. Understand the utility of nuclear medicine in dementias. 2. Discuss the clinical relevance of nuclear medicine imaging in dementias. Prof. Toshimitsu Momose (International University of Health and Welfare, Chiba, Japan) End of session 4

Wednesday, 6 December 2017 AM: Multimedia hall (CoMIT 1F) SESSION 5 09:00-12:00 Parametric image analysis of brain images (including software practice): Dr. Hiroki Kato 12:00-14:00 Lunch Break 14:00-17:00 Technical visit 1. Perform the statistical image analysis and write report by yourself. 2. Discuss the role of Brain Imaging using clinical cases for image interpretation and its relevance in clinical practice End of session 5

Chair: Prof. Jun Hatazawa Thursday 7 December 2017 AM: Multimedia hall (CoMIT 1F) PM: Meeting room B,C (Icho Kaikan 3F) SESSION 6: 9:30-10:10 Theragnostics: Brain tumor and SPECT imaging for brain tumor. Dr. Frederik Giesel (University Hospital Heidelberg, Heidelberg, Germany) the therapy using radiopharmaceuticals for brain tumor. 10:10-10:50 Theragnostics: gastrointestinal tumors and SPECT imaging for gastrointestinal tumors. Prof. UkihideTateishi (Tokyo Medical and Dental University, Tokyo, Japan) the therapy using radiopharmaceuticals for gastrointestinal tumors. 10:50-11:30 Theragnostics: lung cancer and SPECT imaging for lung cancer. Dr. Hirofumi Fujii (National cancer center, Tokyo, Japan) the therapy using radiopharmaceuticals for lung cancer. 11:30-13:10 Lunch Break END OF SESSION 6

SESSION 7: Chair: Dr. Frederik Giesel University Hospital Heidelberg Heidelberg, Germany 13:10-14:00 Theragnostics: thyroid and SPECT imaging for thyroid. Dr. Tatsuya Higashi (National Institute of Radiological Sciences, Chiba, Japan) the therapy using radiopharmaceuticals for thyroid. 14:00-14:40 Theragnostics: liver tumors (TACE and SIRT) and SPECT imaging for liver tumors. Dr. Keigo Osuga ( ) 14:40-15:00 Coffee Break the therapy using radiopharmaceuticals for liver tumors. 15:00-15:50 Theragnostics: malignant lymphoma and SPECT imaging for malignant lymphoma. Dr. Mitsuaki Tatsumi ( ) the therapy using radiopharmaceuticals for malignant lymphoma. END OF SESSION 7

Friday 8 December 2017 Multimedia hall (CoMIT 1F) CHAIR: Dr. Tadashi Watabe SESSION 8 09:00-09:40 Theragnostics: pediatric cancer and SPECT imaging for pediatric cancer. the therapy using radiopharmaceuticals for pediatric cancer. 09:40-10:30 Theragnostics: Prostate cancer and SPECT imaging for prostate cancer. Dr. Keiichiro Yoshinaga (National Institute of Radiological Sciences, Chiba, Japan) Dr. Frederik Giesel (University Hospital Heidelberg, Heidelberg, Germany) the therapy using radiopharmaceuticals for prostate cancer. 10:30-11:10 Future application of theragnostics Prof. Seigo Kinuya (Kanazawa University, Kanazawa, Japan) End of Session 8 11:10-12:00 Closing Remarks Post course evaluation Pascual, Thomas (Technical Officer, IAEA) Prof. Jun Hatazawa Course Director

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