Revision Date 15.11.2011 Version 17.2 SECTION 1. Identification of the substance/mixture and of the company/undertaking 1.1 Product identifier REACH Registration Number A registration number is not available for this substance as the substance or its use are exempted from registration according to Article 2 REACH Regulation (EC) No 1907/2006, the annual tonnage does not require a registration or the registration is envisaged for a later registration deadline. 1.2 Relevant identified uses of the substance or mixture and uses advised against Identified uses Reagent for analysis, Chemical production For additional information on uses please refer to the Merck Chemicals portal (www.merck-chemicals.com). 1.3 Details of the supplier of the safety data sheet Company Merck KGaA * 64271 Darmstadt * Germany * Phone:+49 6151 72-0 Responsible Department EQ-RS * e-mail: prodsafe@merckgroup.com 1.4 Emergency telephone number Please contact the regional company representation in your country. SECTION 2. Hazards identification 2.1 Classification of the substance or mixture Classification (REGULATION (EC) No 1272/2008) Skin corrosion, Category 1A, H314 Corrosive to metals, Category 1, H290 For the full text of the H-Statements mentioned in this Section, see Section 16. Classification (67/548/EEC or 1999/45/EC) C Corrosive R35 For the full text of the R-phrases mentioned in this Section, see Section 16. 2.2 Label elements Labelling (REGULATION (EC) No 1272/2008) Hazard pictograms Signal word Danger Page 1 of 9
Hazard statements H290 May be corrosive to metals. H314 Causes severe skin burns and eye damage. Precautionary statements P280 Wear protective gloves/ protective clothing/ eye protection/ face protection. P301 + P330 + P331 IF SWALLOWED: rinse mouth. Do NOT induce vomiting. P305 + P351 + P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P309 + P310 IF exposed or if you feel unwell: Immediately call a POISON CENTER or doctor/physician. Reduced labelling ( 125 ml) Hazard pictograms Signal word Danger Hazard statements H314 Causes severe skin burns and eye damage. Precautionary statements P280 Wear protective gloves/ protective clothing/ eye protection/ face protection. P301 + P330 + P331 IF SWALLOWED: rinse mouth. Do NOT induce vomiting. P305 + P351 + P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P309 + P310 IF exposed or if you feel unwell: Immediately call a POISON CENTER or doctor/physician. Index-No. 011-002-00-6 Labelling (67/548/EEC or 1999/45/EC) Symbol(s) C Corrosive R-phrase(s) 35 Causes severe burns. S-phrase(s) 26-37/39-45 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable gloves and eye/face protection. In case of accident or if you feel unwell, seek medical advice immediately (show the label where possible). EC-No. 215-185-5 EC Label 2.3 Other hazards None known. SECTION 3. Composition/information on ingredients Formula NaOH HNaO (Hill) CAS-No. 1310-73-2 Index-No. 011-002-00-6 EC-No. 215-185-5 Molar mass 40,00 g/mol Page 2 of 9
Hazardous components (REGULATION (EC) No 1272/2008) Chemical Name (Concentration) CAS-No. EC-No. / Registration number Index-No. Classification sodium hydroxide (<= 100 % ) 1310-73-2 215-185-5 / *) 011-002-00-6 Skin corrosion, Category 1A, H314 Corrosive to metals, H290 *) A registration number is not available for this substance as the substance or its use are exempted from registration according to Article 2 REACH Regulation (EC) No 1907/2006, the annual tonnage does not require a registration or the registration is envisaged for a later registration deadline. For the full text of the H-Statements mentioned in this Section, see Section 16. Hazardous components (1999/45/EC) Chemical Name (Concentration) CAS-No. EC-No. Index-No. Classification sodium hydroxide (<= 100 % ) 1310-73-2 215-185-5 011-002-00-6 C, Corrosive; R35 For the full text of the R-phrases mentioned in this Section, see Section 16. SECTION 4. First aid measures 4.1 Description of first aid measures After inhalation: fresh air. Get medical attention. After skin contact: wash off with plenty of water. Swab with polyethylene glycol 400. Immediately remove contaminated clothing. Consult a physician. After contact with eyes: Rinse with plenty of water keeping eyelids open, protecting the unaffected eye (at least 10 minutes). Seek medical advice immediately! After swallowing: make victim drink water (two glasses at most), avoid vomiting (risk of perforation). Call a physician immediately. Do not attempt to neutralise. 4.2 Most important symptoms and effects, both acute and delayed Irritation and corrosion, collapse, death Risk of blindness! 4.3 Indication of any immediate medical attention and special treatment needed SECTION 5. Firefighting measures 5.1 Extinguishing media Suitable extinguishing media Use extinguishing measures that are appropriate to local circumstances and the surrounding environment. Unsuitable extinguishing media For this substance/mixture no limitations of extinguishing agents are given. 5.2 Special hazards arising from the substance or mixture Not combustible. Ambient fire may liberate hazardous vapours. Page 3 of 9
5.3 Advice for firefighters Special protective equipment for firefighters Stay in danger area only with self-contained breathing apparatus. Prevent skin contact by keeping a safe distance or by wearing suitable protective clothing. Further information Prevent fire extinguishing water from contaminating surface water or the ground water system. SECTION 6. Accidental release measures 6.1 Personal precautions, protective equipment and emergency procedures Advice for non-emergency personnel: Avoid substance contact. Avoid inhalation of dusts. Ensure adequate ventilation. Evacuate the danger area, observe emergency procedures, consult an expert. Advice for emergency responders: Protective equipment see section 8. 6.2 Environmental precautions Do not empty into drains. 6.3 Methods and materials for containment and cleaning up Cover drains. Collect, bind, and pump off spills. Observe possible material restrictions (see sections 7.2 and 10.5). Take up dry. Dispose of properly. Clean up affected area. Avoid generation of dusts. 6.4 Reference to other sections Indications about waste treatment see section 13. SECTION 7. Handling and storage 7.1 Precautions for safe handling Observe label precautions. 7.2 Conditions for safe storage, including any incompatibilities Tightly closed. Dry. Requirements for storage areas and containers No aluminium, tin, or zinc containers. Store at +5 C to +30 C. 7.3 Specific end uses Apart from the uses mentioned in section 1.2 no other specific uses are stipulated. SECTION 8. Exposure controls/personal protection 8.1 Control parameters 8.2 Exposure controls Engineering measures Technical measures and appropriate working operations should be given priority over the use of personal protective equipment. See section 7.1. Page 4 of 9
Individual protection measures Protective clothing needs to be selected specifically for the workplace, depending on concentrations and quantities of the hazardous substances handled. The chemical resistance of the protective equipment should be enquired at the respective supplier. Hygiene measures Immediately change contaminated clothing. Apply preventive skin protection. Wash hands and face after working with substance. Eye/face protection Tightly fitting safety goggles Hand protection full contact: splash contact: Glove material: Glove thickness: Break through time: Glove material: Glove thickness: Break through time: Nitrile rubber 0,11 mm > 480 min Nitrile rubber 0,11 mm > 480 min The protective gloves to be used must comply with the specifications of EC Directive 89/686/EEC and the related standard EN374, for example KCL 741 Dermatril L (full contact), KCL 741 Dermatril L (splash contact). The breakthrough times stated above were determined by KCL in laboratory tests acc. to EN374 with samples of the recommended glove types. This recommendation applies only to the product stated in the safety data sheet<(>,<)> supplied by us and for the designated use. When dissolving in or mixing with other substances and under conditions deviating from those stated in EN374 please contact the supplier of CE-approved gloves (e.g. KCL GmbH, D-36124 Eichenzell, Internet: www.kcl.de). Other protective equipment protective clothing Respiratory protection required when dusts are generated. Recommended Filter type: Filter B-(P3) The entrepeneur has to ensure that maintenance, cleaning and testing of respiratory protective devices are carried out according to the instructions of the producer. These measures have to be properly documented. Environmental exposure controls Do not empty into drains. SECTION 9. Physical and chemical properties 9.1 Information on basic physical and chemical properties Form solid Colour Odour Odour Threshold colourless odourless Page 5 of 9
ph ca. 14 at 50 g/l 20 C Melting point 323 C Boiling point/boiling range 1.390 C at 1.013 hpa Flash point Evaporation rate Flammability (solid, gas) Lower explosion limit Upper explosion limit Vapour pressure at 20 C Relative vapour density Relative density Water solubility Partition coefficient: n- octanol/water Autoignition temperature Decomposition temperature Viscosity, dynamic Explosive properties Oxidizing properties 9.2 Other data Ignition temperature Corrosion 2,13 g/cm³ at 20 C 1.090 g/l at 20 C May be corrosive to metals. SECTION 10. Stability and reactivity 10.1 Reactivity See section 10.3. 10.2 Chemical stability hygroscopic Page 6 of 9
10.3 Possibility of hazardous reactions Risk of explosion with: Metals, Light metals Formed could be: Hydrogen Violent reactions possible with: Nitriles, Alkaline earth metals, ammonium compounds, Cyanides, magnesium, organic nitro compounds, organic combustible substances, phenols, oxidisable substances, acids 10.4 Conditions to avoid Exposure to moisture. 10.5 Incompatible materials Aluminium, brass, Metals, metal alloys, Zinc, Tin 10.6 Hazardous decomposition products no information available When using appropriately hazardous decomposition products are not expected. SECTION 11. Toxicological information 11.1 Information on toxicological effects Acute oral toxicity Symptoms: If ingested, severe burns of the mouth and throat, as well as a danger of perforation of the oesophagus and the stomach. Acute inhalation toxicity Symptoms: burns of mucous membranes, Cough, Shortness of breath, Possible damages:, damage of respiratory tract Skin irritation rabbit Result: Causes burns. (RTECS) Causes severe burns. Eye irritation rabbit Result: Causes burns. (RTECS) Causes serious eye damage. Risk of blindness! Genotoxicity in vitro Mutagenicity (mammal cell test): micronucleus. Result: negative (Lit.) Ames test Result: negative (IUCLID) Teratogenicity Did not show teratogenic effects in animal experiments. (Lit.) Specific target organ toxicity - single exposure The substance or mixture is not classified as specific target organ toxicant, single exposure. Page 7 of 9
Specific target organ toxicity - repeated exposure The substance or mixture is not classified as specific target organ toxicant, repeated exposure. Aspiration hazard Based on available data the classification criteria are not met. 11.2 Further information Quantitative data on the toxicity of this product are not available. Further toxicological data: Systemic effects: collapse, death Further data: Handle in accordance with good industrial hygiene and safety practice. SECTION 12. Ecological information 12.1 Toxicity Toxicity to fish LC50 Oncorhynchus mykiss (rainbow trout): 45,4 mg/l; 96 h (50% solution) (IUCLID) Toxicity to daphnia and other aquatic invertebrates. EC50 Daphnia magna (Water flea): 76 mg/l; 24 h (50% solution) (External MSDS) 12.2 Persistence and degradability Biodegradability The methods for determining biodegradability are to inorganic substances. 12.3 Bioaccumulative potential 12.4 Mobility in soil 12.5 Results of PBT and vpvb assessment PBT/vPvB assessment not available as chemical safety assessment not required/not conducted. 12.6 Other adverse effects Additional ecological information Biological effects: Harmful effect due to ph shift. Forms corrosive mixtures with water even if diluted. Neutralisation possible in waste water treatment plants. Further information on ecology Discharge into the environment must be avoided. SECTION 13. Disposal considerations Waste treatment methods See www.retrologistik.com for processes regarding the return of chemicals and containers, or contact us there if you have further questions. SECTION 14. Transport information ADR/RID UN 1823 SODIUM HYDROXIDE, SOLID, 8, II Environmentally hazardous no Page 8 of 9
IATA UN 1823 SODIUM HYDROXIDE, SOLID, 8, II Environmentally hazardous no IMDG UN 1823 SODIUM HYDROXIDE, SOLID, 8, II EmS F-A S-B Marine pollutant no The transport regulations ADR/RID, IATA - DGR, IMDG -Code are cited according to international regulations and in the form applicable in Germany. Possible national deviations in other countries are not considered. SECTION 15. Regulatory information 15.1 Safety, health and environmental regulations/legislation specific for the substance or mixture EU regulations Major Accident Hazard Legislation 96/82/EC Directive 96/82/EC does not apply Occupational restrictions National legislation Storage class Take note of Dir 94/33/EC on the protection of young people at work. 8 B 15.2 Chemical Safety Assessment For this product a chemical safety assessment was not carried out. SECTION 16. Other information Full text of H-Statements referred to under sections 2 and 3. H290 H314 May be corrosive to metals. Causes severe skin burns and eye damage. Full text of R-phrases referred to under sections 2 and 3 R35 Causes severe burns. Training advice Provide adequate information, instruction and training for operators. Key or legend to abbreviations and acronyms used in the safety data sheet Used abbreviations and acronyms can be looked up at www.wikipedia.org. Regional representation This information is given on the authorised Safety Data Sheet for your country. The information contained herein is based on the present state of our knowledge. It characterises the product with regard to the appropriate safety precautions. It does not represent a guarantee of any properties of the product. Page 9 of 9